Objective: To explore and evaluate a simple and useful indicator for cardiopulmonary function assessment. Methods: College male students were enrolled and received leg lifting (in 30 s, 40 s, 60 s) test and t rhythm squat test (20 times/30 s, 30 times/30 s, 30 times/30 s). Exercise heart rate variability index (EHVI) and heart function index (HFI) was calculated and explored its association with vital capacity and to determine the validity and reliability of cardiopulmonary function indicators through Kappa-tests. Results: No significant associations were found between Leg lifting and squat with absolute and relative vital capacity. Correlation between HFI in rhythm squat test with VO-2max was below 0.2, with some being non-significant. Low but significant correlation was found between EHVI in leg lifting test, especially for EHVI of 60 s leg lifting(r=0.47, P<0.01). The Kappa test showed good consistency between the two measures(Kappa=0.76, P<0.01). Conclusion Exercise heart rate variability index (EHVI) from 60s leg lifting test can be used as a simple indicator for cardiopulmonary function assessment in male college students.