With the improvement of the therapy and the drugs we known more results in a therapeutic ambitious goals of juvenile idiopathic arthritis.Selection of individualized sequential therapy is beneficial to the recovery of the disease.

OBJECTIVE: To study the protective effects of nimesulide, a COX- 2 selective inhibitor on experimental gastric ulcer in rats. METHODS: The gastric ulcer model was established in rats by intragastric administration them with indometacin, 5 min later, which were assigned to receive nimesulide at different dosages ( 200, 100, and 50mg? kg- 1) , 6h later, all the rats were sacrificed. The primary outcome measures were the area of ulcer, levels of SOD, MDA, and GSH in sera and gastric mucosa. RESULTS: As compared with model group, in nimesulide ( at different dosage) groups, the area of ulcer was markedly decreased, level of MDA was decreased while activities of SOD and GSH were increased ( P

The article is intended to introduce the readers to the concept and background of Web accessibility in the United States. I will first discuss different definitions of Web accessibility. The beneficiaries of accessible Web or the sufferers from inaccessible Web will be discussed based on the type of disability. The importance of Web accessibility will be introduced from the perspectives of ethical, demographic, legal, and financial importance. Web accessibility related standards and legislations will be discussed in great detail. Previous research on evaluating Web accessibility will be presented. Lastly, a system for automated Web accessibility transformation will be introduced as an alternative approach for enhancing Web accessibility.

Objective To investigate the curative effect of western combined with traditional Chinese medicine in treatment of acute lumbar disc herniation.Methods 200 patients with lumbar disc herniation were randomly divided into western combined with traditional Chinese therapy group(group A) and western medicine group(group B) ,each group 100 cases.B group was conducted with the general anti - inflammatory, dehydration, nerve pain and nutritional therapy,and A group was given the traditional Chinese medicine treatment on the base of B group.After 3 weeks treatment, the curative effect, VAS score and hospital stay were observed.Results A total effective rate 90.0% in group A was higher than B group 73.0% ( x2 = 3.987 ,P < 0.05); The scores of VAS after treatment 4 weeks[(1.1 ±1.23、0.9 ±0.6)/point]were lower than before treatment[(8.6 ± 1.43,8.8 ± 1.382)/point]in two groups(t =2.301,2.335,all P<0.05) ;The scores of VAS after treatment 3d and 1 week in group A[(5.5 ±0.92) point,(2.7±1.14) point] were lower than group B[(8.2 ±0.59) point,(5.3 ±0.91) point] (t =2.405,2.435,all P<0.05);The hospital days(20.1 ±3.5)d in group A was significantly lower than group B(27.6 ±4.3)d( t = 2.314,P <0.05).Conclusion Western combined with traditional Chinese medicine had better clinical efficacy in teatrent of patients with acute lumbar disc hemiation.

Pediatric allergy,immunology and rheumatology (PAIR) discipline is one of the important branch of pediatrics in China.It covers the pediatric allergic diseases,immunodeficiency diseases,rheumatic diseases and the clinical and research aspect which is associated with infection and immunity including inflammation,and inflammatory diseases,et al.Though it is an interdisciplinary discipline which has a long history and being paid great attention and construction rapidly in early a decade,but it is still in the early stages of development in China.How to promote its reasonable,scientific,and further development quickly to adapt to the high-speed social medical service growth of demand in this field is an important task which we have to face to.This article reviews the discipline development history,present situation and futue trend.

Objective To investigate the application effect of intensified nursing intervention in severe pneumonia complicated with ventilator-associated pneumonia. Methods 78 senile patients admitted to hospital with severe pneumonia complicated with ventilator-associated pneumonia from November 2009 to November 2010 were chosen as the research object.They were randomly divided into the observation group and the control group with 39 cases in each group.The control group was treated with conventional and comprehensive methods of care.The observation group was taken intensified intervention on the basis of the control group.The utility time of ventilator after complication with ventilator-associated pneumonia,hospital stay time,complications and mortality rate for the two groups were compared. Results The utility time of ventilator,hospital stay time,complications and mortality rate for the two groups were compared.The observation group had a clear advantage over the control group,there was significant difference. Conclusions Nursing intervention can be targeted to enhance the improvement of the overall respiratory status in severe pneumonia complicated with ventilator-associated pneumonia.It contributes to inflammation control,and can reduce utility time of ventilator and length of hospital stay,reduce the corresponding incidence of complications and mortality rate,it is worthy of clinical application.

The concept of autoinflammatory diseases and autoimmune diseases is different but similar.With the genetic background and inflammation pathways of many autoimmune diseases elucidated,some kinds of diseases are facing a new partition.The explaination of immunological disease continuum update the concept of some diseases and benefit from the treatment.

After the application of project-based teaching in medical information retrieval course for grade two un-dergraduates of Guangzhou Medical University Vocational Health Technology School was described , the examination records were compared between project-based teaching group and traditional teaching group with the problems sum-marized and measures proposed for their solution .

Objective To investigate the effect of the high school students' authenticity in the relationships with parents and friends on their behavior problems and loneliness.Methods A total of 619 high school students in Guangdong province participated in this study.The instruments included the Authenticity Scale,the Youth Self-Report and the State versus Trait Loneliness Scales.Results (1) Authentic self in the relationship with parents were significantly and negatively related to internalizing problems (depression/anxiety,social withdrawal and somatic complaints,standardized regression coefficients were-0.17,P ＜ 0.01 ;-0.10,P ＜ 0.05 ;-0.10,P ＜ 0.05),externalizing problems (aggression and delinquency,standardized regression coefficients were -0.16,P ＜ 0.01 ;-0.21,P ＜ 0.01) and loneliness (trait loneliness and state loneliness,standardized regression coefficients were-0.17,P ＜0.01 ;-0.17,P ＜0.01).(2) Authentic self in the relationship with friends was significantly and negatively related to internalizing problems (depression/anxiety,social withdrawal and somatic complaints,standardized regression coefficients were-0.24,P＜ 0.01 ;-0.28,P＜ 0.01 ;-0.10,P＜ 0.05) and loneliness(trait loneliness and state loneliness,standardized regression coefficients were-0.29,P ＜ 0.01;-0.34,P ＜0.01).Conclusion Authenticity in the relationships with parents and friends has the positive effect on adolescents' psychosocial adjustment.