The cochlea of children with congenital sensorineural hearing loss with normal inner ear structure was measured and analyzed by high-resolution temporal bone CT(HRCT) imaging technique,its application value before cochlear implantation was evaluated and the appropriate electrode was selected.We collected temporal bone HRCT images of 120 patients with congenital sensorineural hearing loss,according to gender divided into two groups,including 60 males and 60 females.We used the PACS software to measure the distance A(the largest distance from the round window to the lateral wall) and the distance H(height of the cochlea) and calculate the cochlear duct length. Reproducibility of these data were evaluated and the results between the different groups were compared.Measurement of parameter values between the intraobserver and interobserver showed great reproducibility. In the male children group,the measured values are shown as distance A［(8.55±0.31)mm］,distance H［(4.57±0.28)mm］and the cochlear duct length(CDL)［(27.59±1.23)mm］; and in the female children group, the measured values are shown as distance A［(8.45±0.32)mm］,distance H［(4.42±0.34)mm］and the cochlear duct length(CDL)［(27.20±1.17)mm.The A,H,and CDL of the male cochlea were greater than those of the female, the difference was statistically significant(<0.05).Measuring the distance A and distance H of the cochlea and calculating the cochlear duct length CDL can be used to select a suitable length of electrode or to customize a personalized electrode. This is a simple and effective assessment method before cochlear implantation..

OBJECTIVETo investigate the correlation of cytokeratin pan (CKP), vascular endothelial growth factor (VEGF) expression and microvessel density (MVD) to spiral CT manifestations of thymoma.

METHODSEighty-four thymoma patients were underwent spiral CT examination, and 40 of the patients also had enhanced CT examination. All the CT findings were carefully reviewed to analyze their correlation to the expressions of CKP, VEGF and MVD.

RESULTSThe enhancement on spiral CT images increased with the levels of VEGF expression and MVD counting (P<0.01). Significant correlations were observed between VEGF expression, MVD counting and such spiral CT findings as lobular contours, cusp-like or sawtooth-like margins and tumor invasions of the pleural membrane, pericardium and great vessels (P<0.05). CKP expression showed no obvious correlation to these findings by spiral CT.

CONCLUSIONSpiral CT can reflect the pathological characteristics of thymoma, and may serve as a noninvasive modality for preoperative evaluation of thymoma.

Adolescent ; Adult ; Aged ; Female ; Humans ; Keratins ; genetics ; metabolism ; Male ; Microvessels ; Middle Aged ; Thymoma ; blood supply ; diagnostic imaging ; metabolism ; Thymus Neoplasms ; blood supply ; diagnostic imaging ; metabolism ; Tomography, Spiral Computed ; Vascular Endothelial Growth Factor A ; genetics ; metabolism ; Young Adult

BACKGROUND: The Sensory Processing and Self-Regulation Checklist (SPSRC) is a parent or caregiver-reported instrument that measures a child’s self-regulation and sensory processing ability as they perform daily activities. The original version in Chinese and a more recent English version has reported favorable reliability and validity. While the SPSRC has undergone translation into a Tagalog version, its psychometric properties are unknown. OBJECTIVES: This study aims to examine the psychometric properties of the SPSRC-Tagalog. METHODS: Reliability and validity properties were tested among a sample of Filipino children with (n= 45) and without disability (n= 45), based on the reports of the parents or caregivers on the SPSRC-Tagalog. RESULTS: This study found that the SPSRC-Tagalog has good internal consistency, excellent test-retest reliability, and good crosscultural, discriminant, structural, construct, and criterion validity. CONCLUSION The psychometric properties of the SPSRC-Tagalog corroborate with its other language versions in its reliability and validity to measure the sensory processing and self-regulation abilities in Filipino children with and without a disability. The information obtained from the SPSRC-Tagalog may be useful in informing our understanding of sensory processing difficulties among children.