1.Application of transitional care on prevention of scar hyperplasia after burn
Chinese Journal of Modern Nursing 2017;23(17):2262-2265
Objective To explore the application effects of transitional care on the prevention of scar hyperplasia after burn.Methods A total of 110 burn patients, who were treated in our hospital from February 2015 to February 2016, were divided into two groups according to the order of admission, 55 cases respectively. Patients in the control group were given regular discharge guidance and follow-up, while patients in the experimental group were given additional transitional care. The treatment compliance and the score of Vancouver Scale were compared between the two groups at six months after discharge.Results At six months post discharge, the proportions of patients who were prescribed medication, adhered to stress treatment, rehabilitation exercise, and on-time referral in the experimental group were 80.39%, 74.51%, 76.47% and 84.31% respectively, all of which were significantly higher than those in the control group (χ2=9.607, 7.985, 10.471, 11.411,P<0.05). At six months after discharge, the Vancouver scar scores were (6.03±1.98) in the experimental group and (7.56±2.03) in the control group, with statistically significant differences between the two groups (t=-3.815,P<0.05).Conclusions Transitional care can improve the treatment compliance of burn patients and reduce the degree of scar hyperplasia.
2.Endovascular versus Medical Management of Acute Basilar Artery Occlusion: A Systematic Review and Meta-Analysis of the Randomized Controlled Trials
Mohamad ABDALKADER ; Stephanos FINITSIS ; Chuanhui LI ; Wei HU ; Xinfeng LIU ; Xunming JI ; Xiaochuan HUO ; Fana ALEMSEGED ; Zhongming QIU ; Daniel STRBIAN ; Volker PUETZ ; James E. SIEGLER ; Shadi YAGHI ; Kaiz ASIF ; Piers KLEIN ; Yuyou ZHU ; Bruce C.V. CAMPBELL ; Hui-Sheng CHEN ; Simon NAGEL ; Georgios TSIVGOULIS ; Zhongrong MIAO ; Raul G. NOGUEIRA ; Tudor G. JOVIN ; Wouter J. SCHONEWILLE ; Thanh N. NGUYEN ;
Journal of Stroke 2023;25(1):81-91
Background:
and Purpose The optimal management of patients with acute basilar artery occlusion (BAO) is uncertain. We aimed to evaluate the safety and efficacy of endovascular thrombectomy (EVT) compared to medical management (MM) for acute BAO through a meta-analysis of randomized controlled trials (RCTs).
Methods:
We performed a systematic review and meta-analysis of RCTs of patients with acute BAO. We analyzed the pooled effect of EVT compared to MM on the primary outcome (modified Rankin Scale [mRS] of 0–3 at 3 months), secondary outcome (mRS 0–2 at 3 months), symptomatic intracranial hemorrhage (sICH), and 3-month mortality rates. For each study, effect sizes were computed as odds ratios (ORs) with random effects and Mantel-Haenszel weighting.
Results:
Four RCTs met inclusion criteria including 988 patients. There were higher odds of mRS of 0-3 at 90 days in the EVT versus MM group (45.1% vs. 29.1%, OR 1.99, 95% confidence interval [CI] 1.04–3.80; P=0.04). Patients receiving EVT had a higher sICH compared to MM (5.4% vs. 0.8%, OR 7.89, 95% CI 4.10–15.19; P<0.01). Mortality was lower in the EVT group (35.5% vs. 45.1%, OR 0.64, 95% CI 0.42–0.99; P=0.05). In an analysis of two trials with BAO patients and National Institutes of Health Stroke Scale (NIHSS) <10, there was no difference in 90-day outcomes between EVT versus MM.
Conclusion
In this systematic review and meta-analysis, EVT was associated with favorable outcome and decreased mortality in patients with BAO up to 24 hours from stroke symptoms compared to MM. The treatment effect in BAO patients with NIHSS <10 was less certain. Further studies are of interest to evaluate the efficacy of EVT in basilar occlusion patients with milder symptoms.