Objective To investigate the clinical application and value of polyethylene glycol(PEG)electrolyte powder in bowel preparation before CT virtual endoscopy on.Methods 120 cases underwent intestinal CT virtual endoscopy were randomly divided into control group and observation group.The control group (n =60) received oral Mannitol,the observation group (n =60) received oral administration of PEG electrolyte powder.Defecation during medication,bowel preparation for cleanliness,adverse reactions,the amount of water and other aspects were observed in two groups.Results (1) The intestinal preparing total efficiency of the observation group (96.7％) was higher than that of the control group (81.7％),the difference was statistically significant(P ＜ 0.05) ;(2)The patients in the two groups all started defecation in 1 ～5h after taking drugs;(3)In the process of taking the medicine,the incidence rate of adverse reactions such as abdominal distention,nausea and abdominal pain,fatigue and other aspects in the the observation group is lower than that of control group(P ＜ 0.01).Conclusion The clinical effect of PEG electrolyte powder in bowel preparation before CT virtual endoscopy is good.

ObjectivesTo study the current status of child neglect and its inlfuencing factors in children aged 3-6 years in rural Henan.MethodsScales and evaluation methods in the Chinese rural child aged 3-6 years neglected eval-uation model were applied in this study. The neglect rate and the neglect degree were used to describe the neglect status of rural children aged 3-6 years in Henan. The inlfuencing factors for child neglect were also analyzed. ResultsThe total neglect rate in 450 enrolled children was 37.1% (167/450). The total neglect degree was 51.9±6.5. The boys had signiifcant-ly higher neglect rate than girls (P<0.05). There was no significant difference in neglect degree between boys and girls (P>0.05). There were significant differences in neglect rate and neglect degree among the different age groups (P<0.05), the higher neglect rate and higher neglect degree over age. The neglect rate and neglect degree in nuclear families and fam-ilies with three generations were lower than those in single-parent families and remarried families (P<0.05). The neglect rate and neglect degree in non-only children were higher than those in only children (P<0.05). The left-behind children had signiifcantly higher neglect rate and neglect degree than children living with parents (P<0.05). Based on multivariate logis-tic regression analysis, the risk factors of child neglect were single-parent families (OR = 4.78, 95%CI : 2.10-10.87) and remarried families (OR=4.53, 95%CI : 1.99-10.01). The protective factors of child neglect were parents working on sci-ence (OR = 0.20, 95%CI : 0.10-0.67) and living with parents (OR = 0.03, 95%CI : 0.00-0.54).ConclusionsThe neglect status is serious in Henan rural children, particularly in left-behind children.

Objective:To investigate the clinical effect of linezolid combined with levofloxacin in the intensive treatment of tuberculous meningitis.Methods:Seventy-six patients with tuberculous meningitis who underwent intensive treatment from May 2015 to April 2018 in the Fourth People's Hospital of Taiyuan were included in this study. They were assigned to a control group ( n = 38) and an observation group ( n = 38) according to treatment methods. The control group was given conventional treatment (isoniazid + rifampicin + pyrazinamide + ethambutol). The observation group was given treatment with linezolid combined with levofloxacin based on conventional treatment. All patients were treated for 8 successive weeks. Clinical efficacy was compared between the two groups. Results:Total effective rate and the incidence of complications were 92.11% (35/38) and 5.26% (2/38) respectively in the observation group, and they were 68.42% (26/38) and 23.68% (9/38) respectively in the control group. There were significant differences in total effective rate and the incidence of complications between the two groups ( χ2 = 6.727 and 5.028, both P < 0.05). After treatment, white blood cell count, blood glucose level, and protein level were (30.21 ± 4.16) × 10 6/L, (3.65 ± 0.32) mmol/L and (0.79 ± 0.05) g/L, respectively in the observation group, while they were (54.28 ± 6.42) × 10 6/L, (2.18 ± 0.21) mmol/L, (0.98 ± 0.21) g/L, respectively in the control group. There were significant differences in white blood cell count, blood glucose level and protein level between the two groups ( t = 19.396, 23.675, 4.538, all P < 0.05). There was significant difference in the score of quality of life between the control and observation groups [(187.59 ± 4.11) points vs. (216.94 ± 3.90) points, t = 31.933, P < 0.05]. Conclusion:Linezolid combined with levofloxacin based on conventional treatment exhibits better clinical efficacy with high safety in the intensive treatment of tuberculous meningitis than conventional treatment.

Objective To discuss the effect of interferon ?-2a on the radiosensitivity and cell cycle for nasopharyngeal carcinoma cell line CNE-I. Methods Interferon ?-2a was given by different concentration. Then the cells were radiated with X-ray (6?MV) and the cell survival rate was calculated. The change of cell cycle dynamics was measured with flow cytometry. Results The cell survival fraction was 0.62, 0.43 and 0.20 respectively after the interferon ?-2a was given by different concentration(0.5?106, 1.0?106 and 1.5?106?IU/L). The radiosensitization ratio was 1.16, 1.57 and 1.93 respectively. Compared with the control group, increasing cell percentage in G_1 and G_2+M phage and decreasing cell percentage in S phage were observed on 24 h after the interferon ?-2a(1?106?IU/L) was given(P

To explore the effects of Quyu Xiaoban Capsule (QXC) on blood lipid level and platelet activity in coronary heart disease (CHD).A randomized single blinded trial was adopted in 62 cases of CHD. Thirty one cases (control group) were treated with routine western medicine and the rest (QXC group) with QXC added. Serum levels of total cholesterols (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL C) and platelet-activating ? granule membrane protein (GMP 140) were detected before and after treatment.After ten weeks of treatment, GMP 140, TC and TG levels were decreased to various degrees in QXC group, the differences being significant as compared with those in control group and those in QXC group before treatment (P0 05).[Conclusion]QXC can decrease the blood lipid level and improve platelet activity and has a certain effect in preventing and treating CHD.

Objective To formulate genuine case mix plans using medical record information available in China. Methods An account was given of the research background of case mix studies, the current status of the studies and applications at home and abroad, the case mix model for measuring medical "output", data sources and statistical methods of classification. Results Case mix plans for army inpatients, civilian inpatients and outpatients were respectively formulated, and software for calculating the case mix index of a hospital which can run on Windows 95/98 computer systems was developed. Conclusion The theoretical, methodological and data conditions necessary for the formulation of case mix plans based on the first pages of medical records in China are now ripe and the case mix plans formulated on the basis of data from large samples can now be used for the control of medical costs, the assessment of a hospital's medical "output" and the estimation of the financial compensations for hospitals.

Objective:To study the effect of retinoic acid(RA) which is used in malignant tumor therapy on the secretion of C3 and factor B in human lung cancer cell line A549 induced by TNF-? and IL-6.Methods:C3 and factor B in the culture medium were measured by ELISA and Western blot,the mRNA expression of C3 and factor B was analyzed by RT-PCR.Results:When using TNF-?(10 ?g/L),IL-6(50 ?g/L) and RA(1 ?mol/L),the results of ELISA,Western blot and RT-PCR showed that TNF-? and IL-6 promoted A549 cells excreting C3 and factor B and their mRNA expression;RA alone did not affect C3 and factor B;in TNF-? group and TNF-?+RA group,the amounts of C3 were 91.40?12.59 and 133.59?11.25(ng/10~6 cells) respectively(P0.05),and the amounts of factor B were 13.07?2.50 and 32.89?4.22(ng/10~6 cells) respectively(P

Objective To assess the predicting value of homocysteine ( HCY), low density lipoprotein cholesterin (LDL-C) and carotid intima-media thickness (IMT) for women with coronary artery disease (CAD). Methods To choose 115 patients with CAD and 102 patients of non-CAD;Homocysteine, LDL-C and IMT were assayed respectively;comparison and correlation analysis were performed based on genders. Results The rates for hyperhomocysteinemia and High Lipoproteinaemia in female CAD patients are 59. 6% and 75.0%,respectively,while they are 69. 9% and 78.6% for male CAD patients,which are both remarkably higher than 23.0% ,26.7%, 22. 2% and 23.6% in non-CAD patients ( Ps ＜ 0. 05 ). ROC curve shows that the best diagnostic boundary point is 0.953 mm for female IMT and 1. 021 mm for male IMT. At the boundary point,the sensitivity,specificity,positive predictive value and negative predictive value are 83.7% ,91.4% ,95.7% and 63. 8% in female, much higher than 62.9%, 65.3%, 76.2% and 53.3% in male. Conclusion hyperhomocysteinemia, high lipoproteinaemia are the important risk factors for women with coronary artery disease;IMT might be used as the predictor of CAD, which have more advantages for female than for male patients.

Objective To compare the dosemetry between helical tomotherapy (HT) and intensity-modulated radiotherapy (IMRT) for early-stage postoperative breast cancer and provide more valuable evidences to the clinical researches. Methods Clinical trails of dosimetric comparing between HT and IMRT for early-stage breast cancer were obtained from PubMed, Embase, Sciencedirect, CNKI, VIP and Wanfang databases, evaluated and analyzed with the Cochrane Collaboration's RevMan 5.2 software. Results 10 studies were included with a total of 135 patients. Compared to IMRT plans, HT plans provided a significantly better conformity index (P<0.000 1), mean (P<0.000 01) and maximal dose (P=0.003) of the planning target volume (PTV). HT plans had a lower heart maximal dose (P=0.005), V20 (P=0.05), V30 (P=0.003), and ipsilateral lung maximal dose (P=0.003), V20 (P=0.02), as while as had a higher contralateral breast V5 (P=0.01), mean (P=0.05) and maximal dose (P<0.000 01). There was no significantly difference between HT and IMRT plans for homogeneity index of PTV, heart V5, V10, mean dose, ipsilateral lung V5, V10, V30, mean dose, contralateral breast V10, contralateral lung mean and maximal dose (all P >0.05). Conclusion Compared to IMRT plans, HT plans have the dosimetry superiority for early-stage breast cancer with significantly better coverage and dose conformity while maintaining lower doses to high risk organs.

Objective To investigate the correlation among mammographic features, and estrogen /progesterone receptor(ER,PR) of the breast cancer.Methods The mammographic features of 60 cases of breast cancer confirmed by surgery and histology were analyzed retrospectively. The specimens of mastectomy of the breast cancer were stained with immunohistochemistry,the expression of estrogen receptor (ER) and progesterone receptor (PR) were measured .The relationship between the immunohistochemical pathologic results and mammographic features were analyzed. Results Among the 60 cases of breast cancers, X-ray types mass of breast cancer were correlated with the expression of PR (P