Objective To explore the application value of aspirin and clopidogrel dual antiplatelet treatment combined with ABCD3-Ⅰ scores in treatment of transient ischemic attack (TIA).Methods Risk factors were evaluated and imaging was performed in 48 h in one hundred and twenty patients with first attack of TIA [magnetic resonance imaging (MRI),magnetic resonance angiography (MRA),diffusion weighted imaging (DWI) scan].According to the ABCD3-Ⅰ evaluation method,the patients were divided into low risk group,moderate risk group and high risk group.Single resistance group was given aspirin 100 mg/d; double resistance group was given aspirin 100 mg/d combined with clopidogrel 75 mg/d.Then the incidence of ischemic stroke in each group within 7 days was observed,and the effects of dual anti-platelet and aspirin monotherapy were compared.Results Within 7 d after TIA,low-risk single resistance group and low-risk double resistance group had no stroke; 9 cases (42.9％,9/21) had stroke in moderate-risk single resistance group,2 cases (2/19) had stroke in moderate-risk double resistance group,and there was significant difference (P ＜ 0.05) ; 9 cases (9/18) had stroke in high-risk single resistance group,3 cases (15.0％,3/20) had stroke in high-risk double resistance group,and there was significant difference (P ＜ 0.05).Three patients in single resistance group and 4 cases in double resistance group showed gastrointestinal adverse reactions such as nausea,acid reflux,and there was no significant difference between 2 groups (P ＞ 0.05).Each group during treatment showed no bleeding tendency,and liver and kidney function in patients was normal.Conclusion In patients of the moderate risk and high risk of ABCD3-Ⅰ scores,dual anti-platelet may have an advantage over single druge in the prevention of ischemic stroke.

Objective To explore the effects of Taiji exercise on the psychology and the functions of the autonomic nervous systems of middle aged and elderly people. Methods Two hundred and seven middle aged and elderly Taiji exercisers and 166 age matched non Taiji exercisers were sampled. The Zung Self rating Anxiety Scale(SAS), Zung Self rating Depression Scale (SDS) and autonomic nervous system equilibrium index (ANSEI)were adopted to assess the subjects. Results Compared with those of the control group, the scores of SAS and SDS in Taiji group were significantly higher, and the equilibrium of autonomic nervous systems in Taiji group was also superior. There was no significant difference between the male and the female with regard to SAS, SDS and the equilibrium of autonomic nervous systems within Taiji group. The longer the exercise, the better the equilibrium of autonomic nervous systems. Conclusion Taiji exercise has positive effects on the psychology and the autonomic nervous system of the middle aged and the elderly.

The vascular depression is a subtype of depression.It has its specificity in clinical features,imaging,and treatment outcome etc.This article reviews the advances in research on the aspects of risk factors,pathogenesis,diagnosis,clinical features,and outcomes of vascular depression,particularly the vascular risk factors,steady-state changes in the neurovascular unit,immune cytokine activation,imaging characteristics of white matter damage and treatment of repetitive transcranial magnetic stimulation as well as its correlation with dementia and cardiocerebrovascular diseases.

Objective We aimed to translate the English version of Perceived Control of Asthma Questionnaire (PCAQ) into Chinese and to test the reliability and validity of the Chinese version of PCAQ in asthma patients.Methods Totally 125 patients with asthma were recruited and were investigated by the Chinese version of PCAQ.The results underwent reliability and validity test.Results The Cronbach's α coefficient of the Chinese version of PCAQ ranged from 0.815 to 0.904,higher than 0.7.The split half coefficient was 0.647; the test-retest reliability was 0.818,which showed that internal consistency of Chinese version of PCAQ was good.The content validity index was 0.952.Factor analysis got 3 factors,which explained 46.079％ of the total variance; the factor loading of each item was ＞0.4.Conclusions The Chinese version of PCAQ has been proved to be rehable and valid.It can be used as a valid tool for the measurement of perceived control in asthma patients.

Objective To explore the value of ABCD3-Ⅰ score in predicting prognosis of transient ischemic attack (TIA).Methods A total of 106 TIA patients were evaluated according to ABCD2,ABCD3 and ABCD3-Ⅰ criteria.The occurrence of cerebral infarction within 7 d and 90 d was observed.The patients with ABCD3-Ⅰ 0-3 scores were as low risk group (36 cases),the patients with ABCD3-Ⅰ 4-7 scores were as moderate risk group (36 cases),the patients with ABCD3-Ⅰ 8-13 scores were as high risk group (34 cases).Results The occurrence of cerebral infarction within 7 d and 90 d in high risk group was lower than that in low risk group and moderate risk group [within 7 d:23.5％(8/34) vs.2.8％(1/36) and 5.6％ (2/36),within 90 d:38.2％ (13/34) vs.2.8％ (1/36) and 11.1％ (4/36)],and there was significant difference (P ＜0.01).Symptom duration time ≥10 min in ABCD3-Ⅰ score,concomitant diabetes,double TIA,ipsilateral carotid artery stenosis ≥50％,high sign in diffusion weighted imaging were the risk factors for the occurrence of cerebral infarction within 7 d and 90 d in TIA patients (P ＜ 0.05).The area under the receiveroperating characteristic curve for predicting the occurrence of cerebral infarction within 7 d and 90 d in TIA patients by ABCD3-Ⅰ score was higher than that by ABCD2 and ABCD3 score (0.914 vs.0.614 and 0.877,0.869 vs.0.633 and 0.773).Conclusion The ABCD3-Ⅰ score is a simple and effective way to judge the short-term prognosis of TIA and can help to identify the different risk levels,so it is helpful in stratification treatment.

Objective To evaluate the efficacy of laparoscopic ovarian drilling for treating clomiphene-resistant polycystic ovary syndrome(PCOS).Methods Laparoscopic ovarian drilling,with pelvic adhesion release and salpingoplasty,was performed in 38 cases of clomipheneresistant PCOS from March 2001 to May 2005 in this hospital.Serum concentrations of luteinizing hormone(LH),follicle-stimulating hormone(FSH),androgen(T),and estradiol(E2) were measured before and after operation.Ovarian follicular development,pregnancy rate,and abortion rate were observed after operation. Results Postoperatively,there was a significant decline of levels of LH(from 22.36?3.17 U/L to 8.73?1.95 U/L;t=3.13,P

Objective: To develop the native Chinese Affective Picture System (CAPS) for future research on emotion. Methods: 852 pictures were screened out to make up of CAPS. 46 Chinese university students were collected to rate the valence, arousal and dominance by self-report in a 9-point rating scale for CAPS. Results: The standard deviations of scores on valence and dominance were greater than that on arousal. Scatter plot showed that the score distribution on the dimension of valence and arousal was wide in CAPS. Conclusion: Though IAPS (International Affective Picture System) is highly internationally-accessible, there are still significant differences between the two sources. The native Chinese Affective Picture System is necessary.

Objective To investigate the relationship of mental status,personality characterstics and TCM syndromes of spontaneous abortion(SA).Methods Symptom Checklist 90,Measure of Mental Health,Eysenck Personality Questionnaire and Diagnostic Questionnaire of TCM syndromes were adopted.Multifactorial analysis was fitted by non-conditional logistic regression model.Results In patients with SA,a positive correlation of somatization factors and kidney dificiency,spleen deficiency,blood heat and liver-qi stagnation.A positive correlation was also found between hostility factors and kidney deficiency,obsessive-compulsive factors and liver-qi stagnation.Patients with melancholic temperament tended to manifest as the syndromes of kidney deficiency,spleen deficiency and liver-qi stagnation,and choleric temperament tended to manifest as blood heat and liver-qi stagnation.Conclusion The syndromes of kidney deficiency,spleen deficiency,blood heat and liver-qi stagnation at least partially reflect the psychosomatic reaction or psychosomatic disorder induced by mental factors.TCM syndromes has a relationship with mental status and personality characteristics.The nature of their relationship needs to be studied further.

Purpose:To evaluate the therapeutic effect of paclitaxel and platinum containing chemotherapy (cisplatin or carboplatin) in women with epithelial ovarian cancer.Methods:We assigned 16 cases with advanced epithelial ovarian cancer after initial surgery to receive paclitaxel and cisplatin or carboplatin. Pcalitaxel (135 mg/m 2,over a period of 10 hours ) was administered iv once every 3 to 4 weeks, 24 control cases were treated with "CAP" or "CVP" regimen. Results:The overall median survival was significantly longer in the paclitaxel platinum group than in the cisplatin cyclophosphamide group (median, 35 vs. 22.5 months, P

Objective We tried to translate the English version of the Falls Efficacy Scale,Swedish version [FES (S)] into Chinese and test the reliability and validity of the Chinese version of FES (S) in patients after stroke.Methods Totally 145 patients after stroke were recruited and were investigated by the Chinese version of FES (S).The result underwent analysis of reliability and validity.Results The internal consistency coefficient of the Chinese version of FES (S) were 0.896.The Cronbach's α coefficient of two dimensions,which were Activity of Daily Living Ability and Instrumental Activity of Daily Living,were 0.863 and 0.872.The split half coefficient was 0.653,test-retest reliability was 0.743.The content validity index(CVI)was calculated according to related formulas,which was 0.896～1.000,the average CVI of all items was 0.925,CVI of each item was above 0.8.Factor analysis got two factors,which explained 40.852％ of the total variance.Except for item 5,other items showed factor loading ＞0.4 for its common factor.Conclusions The Chinese version of FES (S) has been proved to be reliable and valid.It can be used as a valid tool for assessing stroke patients with risk for falls and self-confidence.