OBJECTIVE: To provide reference to the service improvement of Chinese drug store. METHODS: The service in drugstores was classified into basic service, pharmaceutical service, medical service and health information service. Each category was analyzed specifically. RESULTS & CONCLUSIONS: Based on the practice, the drug store should choose the proper combination of service category, which are beneficial to drugstores to shape up their own competitive edge and promote sustainable development.

Objective To study the degradation of hepatitis C virus(HCV) genome before and after methylene blue photochemistry(MB-P) treatment of the plasma.Methods MB was added to HCV positive plasma to a final concentration of 1.0?mol/L.The plasma was then exposed to 30000 Lux fluorescence.Plasma samples were then collected at different times of exposure.Real-time PCR was used to quantitatively study the course of the HCV-RNA degradation.The whole genome was screened for integrity by RT-PCR with 8 pairs of specific primers which targeted sequential overlapping sections of HCV genome.Results Results of real-time PCR showed that the copy number of HCV-RNA was continuously decreasing during MB-P treatment.RT-PCR results showed that the reactivity of different sections of the HCV genome to MB-P was significantly different and indicated that the 5' end and 3' end were more stable. Conclusion MB-P treatment could degrade HCV RNA with various sensitivities to different sections of the genome.RNA degradation may play an important role in plasma virus inactivation.Detection of HCV genomic RNA might be clinically useful to monitor the process and efficiency of virus inactivation.

Objective To realize the contamination status of dental unit waterlines (DUWL)in general hospitals, and provide scientific evidence for making preventive measures.Methods Three hospitals were selected for study, water source adopted by hospital A,B and C was running water,reservoir water,and filtered water through reverse osmosis filtration system respectively,specimens of dental handpiece spray water and flushing water of dental chair units were collected quarterly,total bacterial colony in water were detected.Results The qualified rate of source wa-ter,handpiece spray water,and flushing water in hospital A was 75.00%(3/4),0 (0/40)and 0 (0/40)respectively,col-ony count of handpiece spray water and flushing water was (1.20×103 -5.53×104 )CFU/mL(M=3.80×104 CFU/mL) and (2.11×104 -1.66×105 )CFU/mL(M=4.80×104 CFU/mL)respectively.The qualified rate of source water,hand-piece spray water,and flushing water in hospital B was 50.00%(2/4),60.00%(24/40)and 72.50%(29/40)respectively, colony count of handpiece spray water and flushing water was (0.00 -3.71 ×106 )CFU/mL(M=83.00 CFU/mL)and (0.00-2.39×106 )CFU/mL(M=72.00 CFU/mL)respectively.The qualified rate of source water,handpiece spray wa-ter,and flushing water in hospital C was 100.00%(4/4),55.00%(22/40)and 65.00%(26/40)respectively,colony count of handpiece spray water and flushing water was (0.00-6.20×103 )CFU/mL(M=96.00 CFU/mL)and(0.00-1.63×103 )CFU/mL(M=87.50 CFU/mL)respectively.Conclusion Water of DUWL in general hospitals is seriously con-taminated,disinfection and standardized management of source water and DUWL must be strengthened.

Objective To investigate whether ultrasonic coupling agent (UCA)can produce shielding or antago-nistic effect on iodine disinfectant for preoperative skin disinfection.Methods Shielding or antagonistic effect of UCA on iodine disinfectant were detected by laboratory carrier immersion killing test and on-the-spot skin disinfec-tion test.Results Antagonistic effect:after the mixing of iodophor with UCA,the average killing rate of iodophor containing available iodine 2 500mg/L and 625 mg/L to Staphylococcus aureus decreased from 100.00% to 99.67%-99.78% and 96.85 % - 98.25 %,respectively;the average killing rate to Escherichia coli decreased from 100.00% to 99.71 %-99.82% and 95 .93 %-98.56%,respectively.Shielding effect:after smearing with UCA, the average killing rate of iodophor and iodine tincture + alcohol to Escherichia coli decreased from 100.00% to 30.76% and 100.00% to 94.48%,respectively;the average killing rate to Staphylococcus aureus decreased from 99.99% to 55 .55 % and 100.00% to 98.22%,respectively.On-the-spot skin disinfection test:the killing rate of io-dophor and iodine tincture +alcohol to natural bacteria on skin surface were both 99.99%,after skin was smeared with UCA,the killing rate decreased to 92.62% and 93 .57%,respectively.Conclusion UCA remained on the oper-ative field has shielding and antagonistic effect on iodine disinfectant.

Objective:To prevent the possible effects of population aging and find out countermeasures to ensure the sustainable development of basic medical insurance fund balances.Methods:Using system dynamics,by coupling the three subsystems of basic medical insurance fund income,basic medical insurance fund expenditure,and population size,a causal relationship diagram and stock flow diagram are drawn to construct a system dynamics model,and Vensim Software is used for simulation.Results:Under the predicted natural conditions,the balance of the basic medical insurance fund will show a trend of first increasing and then decreasing from 2023 to 2030.Adjusting and combining the three variables of retirement strategy,outpatient visits,and participation rate into four solutions,among which simultaneously implementing the prediction plan of delaying retirement,expanding basic medical insurance coverage,and strengthening elderly health management can significantly reduce the decline of the basic medical insurance fund.Conclusion:The aging population will be detrimental to the sustainable development of the surplus of the basic medical insurance fund.Based on this,the following suggestions are proposed:implement appropriate delayed retirement policies to increase the income of the basic medical insurance fund;further expand the coverage of insured individuals to enhance the risk resistance of the basic medical insurance fund;strengthen the health management of the elderly to control the excessively rapid growth of the basic medical insurance fund expenditures.

Objective:To prevent the possible effects of population aging and find out countermeasures to ensure the sustainable development of basic medical insurance fund balances.Methods:Using system dynamics,by coupling the three subsystems of basic medical insurance fund income,basic medical insurance fund expenditure,and population size,a causal relationship diagram and stock flow diagram are drawn to construct a system dynamics model,and Vensim Software is used for simulation.Results:Under the predicted natural conditions,the balance of the basic medical insurance fund will show a trend of first increasing and then decreasing from 2023 to 2030.Adjusting and combining the three variables of retirement strategy,outpatient visits,and participation rate into four solutions,among which simultaneously implementing the prediction plan of delaying retirement,expanding basic medical insurance coverage,and strengthening elderly health management can significantly reduce the decline of the basic medical insurance fund.Conclusion:The aging population will be detrimental to the sustainable development of the surplus of the basic medical insurance fund.Based on this,the following suggestions are proposed:implement appropriate delayed retirement policies to increase the income of the basic medical insurance fund;further expand the coverage of insured individuals to enhance the risk resistance of the basic medical insurance fund;strengthen the health management of the elderly to control the excessively rapid growth of the basic medical insurance fund expenditures.

Objective:To prevent the possible effects of population aging and find out countermeasures to ensure the sustainable development of basic medical insurance fund balances.Methods:Using system dynamics,by coupling the three subsystems of basic medical insurance fund income,basic medical insurance fund expenditure,and population size,a causal relationship diagram and stock flow diagram are drawn to construct a system dynamics model,and Vensim Software is used for simulation.Results:Under the predicted natural conditions,the balance of the basic medical insurance fund will show a trend of first increasing and then decreasing from 2023 to 2030.Adjusting and combining the three variables of retirement strategy,outpatient visits,and participation rate into four solutions,among which simultaneously implementing the prediction plan of delaying retirement,expanding basic medical insurance coverage,and strengthening elderly health management can significantly reduce the decline of the basic medical insurance fund.Conclusion:The aging population will be detrimental to the sustainable development of the surplus of the basic medical insurance fund.Based on this,the following suggestions are proposed:implement appropriate delayed retirement policies to increase the income of the basic medical insurance fund;further expand the coverage of insured individuals to enhance the risk resistance of the basic medical insurance fund;strengthen the health management of the elderly to control the excessively rapid growth of the basic medical insurance fund expenditures.

Objective:To prevent the possible effects of population aging and find out countermeasures to ensure the sustainable development of basic medical insurance fund balances.Methods:Using system dynamics,by coupling the three subsystems of basic medical insurance fund income,basic medical insurance fund expenditure,and population size,a causal relationship diagram and stock flow diagram are drawn to construct a system dynamics model,and Vensim Software is used for simulation.Results:Under the predicted natural conditions,the balance of the basic medical insurance fund will show a trend of first increasing and then decreasing from 2023 to 2030.Adjusting and combining the three variables of retirement strategy,outpatient visits,and participation rate into four solutions,among which simultaneously implementing the prediction plan of delaying retirement,expanding basic medical insurance coverage,and strengthening elderly health management can significantly reduce the decline of the basic medical insurance fund.Conclusion:The aging population will be detrimental to the sustainable development of the surplus of the basic medical insurance fund.Based on this,the following suggestions are proposed:implement appropriate delayed retirement policies to increase the income of the basic medical insurance fund;further expand the coverage of insured individuals to enhance the risk resistance of the basic medical insurance fund;strengthen the health management of the elderly to control the excessively rapid growth of the basic medical insurance fund expenditures.

Objective:To prevent the possible effects of population aging and find out countermeasures to ensure the sustainable development of basic medical insurance fund balances.Methods:Using system dynamics,by coupling the three subsystems of basic medical insurance fund income,basic medical insurance fund expenditure,and population size,a causal relationship diagram and stock flow diagram are drawn to construct a system dynamics model,and Vensim Software is used for simulation.Results:Under the predicted natural conditions,the balance of the basic medical insurance fund will show a trend of first increasing and then decreasing from 2023 to 2030.Adjusting and combining the three variables of retirement strategy,outpatient visits,and participation rate into four solutions,among which simultaneously implementing the prediction plan of delaying retirement,expanding basic medical insurance coverage,and strengthening elderly health management can significantly reduce the decline of the basic medical insurance fund.Conclusion:The aging population will be detrimental to the sustainable development of the surplus of the basic medical insurance fund.Based on this,the following suggestions are proposed:implement appropriate delayed retirement policies to increase the income of the basic medical insurance fund;further expand the coverage of insured individuals to enhance the risk resistance of the basic medical insurance fund;strengthen the health management of the elderly to control the excessively rapid growth of the basic medical insurance fund expenditures.

Objective:To prevent the possible effects of population aging and find out countermeasures to ensure the sustainable development of basic medical insurance fund balances.Methods:Using system dynamics,by coupling the three subsystems of basic medical insurance fund income,basic medical insurance fund expenditure,and population size,a causal relationship diagram and stock flow diagram are drawn to construct a system dynamics model,and Vensim Software is used for simulation.Results:Under the predicted natural conditions,the balance of the basic medical insurance fund will show a trend of first increasing and then decreasing from 2023 to 2030.Adjusting and combining the three variables of retirement strategy,outpatient visits,and participation rate into four solutions,among which simultaneously implementing the prediction plan of delaying retirement,expanding basic medical insurance coverage,and strengthening elderly health management can significantly reduce the decline of the basic medical insurance fund.Conclusion:The aging population will be detrimental to the sustainable development of the surplus of the basic medical insurance fund.Based on this,the following suggestions are proposed:implement appropriate delayed retirement policies to increase the income of the basic medical insurance fund;further expand the coverage of insured individuals to enhance the risk resistance of the basic medical insurance fund;strengthen the health management of the elderly to control the excessively rapid growth of the basic medical insurance fund expenditures.