1.The effect of scan position consistency on automatic registration of computer tomography-magnetic resonance images in patients with nasopharyngeal carcinoma
Zhanyu WANG ; Haixin HUANG ; Dongning HUANG ; Yusong LONG
Chinese Journal of Radiation Oncology 2009;18(6):435-437
Objective To study the effect of scan position consistency on computer tomography-magnetic resonance (CT-MR) images automatic registration in patients with nasopharyngeal carcinoma.Methods Fifteen patients with nasopharyngeal carcinoma were enrolled in this study and scanned with the same position to acquire CT images and MR-1 images. Then they were reacanned with different position for MR-2 images. Image registration of CT-MR-1 and CT-MR-2 was finished using mutual information method.The registration errors were evaluated by measuring the distances between marks. Results The error of au-tomatic CT-MR registration with consistent scan position was 1.32 nun, comparing with the minimum of 2.00 ram and the maximum of 3.83 mm with different positions. Conclusion Keeping consistent scan position can improve the accuracy of image registration.
2.Effects of Danqi Granules combined with Xianling Gubao Capsules on bone metabolism and bone mineral density in patients with postmenopausal osteoporotic vertebral compression fractures after surgery
Yusong CHEN ; Xiaotao HUANG ; Lve FANG ; Jinjin LAO ; Yekai DONG
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):33-34,37
Objective To observe the effects of Danqi Granules combined with Xianling Gubao Capsules on bone metabolism and bone mineral density (BMD) in patients with postmenopausal osteoporotic vertebral compression fractures (OVCF) after surgery. Methods 90 cases of postmenopausal women with OVCF were randomly divided into the control group and the observation group, 45 cases in each group. The two groups were treated by vertebroplasty (PVP), and after the surgery, the control group was treated with Xianling Gubao Capsules while the observation group was additionally given Danqi Granules. The serum markers of bone metabolism [(25 (OH) D, PINP, β-CTX] and BMD of L2-4 and left femoral neck were detected before and after treatment. Results The level of serum 25 (OH) D in the observation group after treatment was significantly higher while the levels of PINP and β-CTX were significantly lower than those in the control group (P<0.05), and the BMD of L2-4 and left femoral neck of the observation group were significantly higher than those of the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion Danqi Granules combined with Xianling Gubao Capsules can significantly accelerate fracture recovery, and improve bone mineral density in the treatment of postmenopausal women with OVCF.
3.The expression of anti-apoptosis gene bag-1 and its relation to the differentiation of intrahepatic cholangiocarcinoma
Qingguo YAN ; Wenyong WANG ; Yusong LI ; Peizhen HU ; Gaosheng HUANG ; Wenliang WANG
Chinese Journal of General Surgery 1993;0(02):-
Objective To investigate the expression of anti-apoptosis gene bag-1 and its relation to the differentiation of intrahepatic cholangiocarcinoma (ICC). Methods Immunohistochemical techniques were adopted to study the expression of bag-1 in ICC tissue ( n=48) and para-hepatocarcinoma bile duct ( control group, n=25). Results Expression of bag-1 in the ICC group was significantly higher than that in the control group. In the ICC group (P
4.Effect of extubation time of indwelling urinary catheters on postoperative recovery after cesarean section.
Bi ZHOU ; Zhihai LIN ; Yusong HUANG
Journal of Southern Medical University 2012;32(8):1221-1222
OBJECTIVETo study the effect of extubation time of indwelling urinary catheters on postoperative recovery after cesarean section.
METHODSA total of 138 parturients undergoing elective cesarean delivery were randomized into experimental group and control group to have the urinary catheters removed at 6-8 h and 24 h after cesarean section, respectively.
RESULTSCompared with the control group, the experimental group showed significantly decreased incidences of urinary tract infection and urethral irritation (P<0.05), with also a significantly increased rate of autonomous urination and a higher degree of comfort (P<0.05) after removing the catheter.
CONCLUSIONA shortened indwelling time of urinary catheters can promote postoperative recovery after cesarean section.
Adult ; Catheters, Indwelling ; Cesarean Section ; rehabilitation ; Device Removal ; Female ; Humans ; Postoperative Period ; Pregnancy ; Time Factors ; Young Adult
5.The study of characteristic of serum Lp(a)level in in patients with chronic kidney disease
Qijian HUANG ; Jin ZHANG ; Decai QIAN ; Hongfu ZHANG ; Liang CHEN ; Yajie WANG ; Qiang WANG ; Lamei LIAO ; Yusong LIU ; Rulan CHENG ; Weijun ZHAO ; Jihong LIU ; Sheng LUO ; Jun ZHENG ; Jun LIU ; Fangfang LI ; Jianping HUANG
Chinese Journal of Primary Medicine and Pharmacy 2017;24(2):161-164
Objective To investigate the characteristic of lipoprotein(a)[Lp(a)]in different phases of chronic kidney disease (CKD ),to provide the basis for clinical prevention and treatment of CKD.Methods 200 patients with CKD in the Republic Hospital of Shifang were collected as study group,including 5 phases (every phase had 40 cases),and 100 healthy people were selected as control group.Measured the serum Lp(a)of both study and control group,analyzed the correlations between Lp(a)and different phase of CKD.All data were analyzed by SPSS version 17.0.The significant level was established at 0.05.Results CKD1 [(146.0 ±95.5)mg/L]and all CKD group [(231.5 ±133.2)mg/L]had higher level of serum Lp(a)than the control group [(115.5 ±70.2)mg/L] (Z=-2.800,P<0.05 and Z=-7.922,P<0.05).CKD3 had higher Lp(a)level than CKD2(Z=-2.069,P<0.05 ),while there were no significant differences between each of the other two groups.CKD4 -5 [(325 .0 ± 194.7)mg/L]also had higher Lp(a)level than CKD1 -3 [(182.0 ±110.5)mg/L](Z=-4.439,P<0.05). Conclusion Patients with CKD always have high level of serum Lp(a),which have been slowly increased since CKD1 ,meanwhile the level of Lp(a)may have a certain correlation with the stage of CKD development,since Lp(a) is an important promoting factor in the progress of CKD.
6.A Cohort Study of Invigorating Qi and Dissipating Depression Herbs on Depressive Disorders in the Clinical Efficacy
Zehua ZHAO ; Yusong YANG ; Xile YANG ; Shijing HUANG ; Juhua PAN ; Yuxia CHEN
World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(12):3843-3850
Objective To evaluate the dynamic efficacy of Invigorating Qi and Dissipating Depression Herbs in the treatment of depressive disorders and its effect on recurrence rate and suicidal thoughts.Methods The prospective cohort study was used to divide the patients into three cohorts according to the different exposure factors(treatment regimens):Western medicine group,integrated traditional Chinese and Western medicine group,and Invigorating Qi and Dissipating Depression Herbs group,and followed up for 2 years,and the treatment effects of each cohort at half a year,one year,one and a half years,and two years were observed respectively,and the evaluation indicators were Montgomery Depression Scale(MADRS),Hamilton Anxiety Scale(HAMA)and Social Deficit Screening Scale(SDSS)reduction rates,and endpoint events(relapse,suicidal ideation)incidence;By comparing the efficacy and endpoint event rate of the three cohorts,the effect of Invigorating Qi and Dissipating Depression Herbs on improving depressive disorders was evaluated.Results A total of 409 patients(67 in the Western medicine group,131 in the integrated traditional Chinese and Western medicine group,and 211 cases in the Invigorating Qi and Dissipating Depression Herbs group)were enrolled,and the rate of score reduction after treatment with MADRS,HAMA and SDSS increased compared with the pre-treatment treatment with the extension of the drug taking time.The difference between the MADRS and SDSS reduction rates in the Invigorating Qi and Dissipating Depression Herbs group on taking the drug for half a year and the SDSS reduction rate on one year of taking the drug were statistically significant compared with the Western medicine group,and there was no significant difference compared with the integrated Chinese and Western medicine group.On one and a half years and two years of medication,the integrated Chinese and Western medicine group had more advantages in MADRS reduction rate than the Invigorating Qi and Dissipating Depression Herbs group.The recurrence rates of depression in the three groups within 2 years were 20.9%,30.5%and 36.0%,and the difference was not statistically significant,and the length of taking medication was used as a protective factor by logistic regression analysis.The incidence rates of suicidal thoughts were 44.8%,19.1%and 17.5%,and the differences were statistically significant,and the exposure factors and income level were the protective factors by logistic regression analysis.Conclusion Invigorating Qi and Dissipating Depression Herbs can significantly improve the depressive state of patients,promote the recovery of social function,reduce the occurrence of long-term suicidal ideation,and appropriately extend the time of taking medicine can increase the long-term efficacy and reduce recurrence.
7.Investigation of the application of nosocomial infection prevention and control measures as stipulated in COVID-19 pandemic emergency plans
Yang CAO ; Yinghong WU ; Xiulan CHANG ; Hui CHEN ; Liang GUO ; Jing HUANG ; Fengmin JI ; Gehong LI ; Huifang LI ; Kun LIU ; Rong LIU ; Cuiling WANG ; Hong WANG ; Yuxia WANG ; Xinbing XU ; Yanqiu YANG ; Yusong YANG ; Aihua ZHANG ; Wenyan ZHANG
Chinese Journal of Hospital Administration 2020;36(10):818-822
Objective:To learn the application of nosocomial infection prevention and control measures as stipulated in COVID-19 emergency plans by medical institutions at all levels in the region, for the purpose of strengthening epidemic prevention and control.Methods:During March 12-13, 2020, customized questionnaires were used to learn from 186 hospitals and medical institutions regarding the basics of their nosocomial prevention management departments, emergency plan application and revisions made. Comparison of the ratios or constituent ratios were tested with χ2 test, while the continuous variables analysis between groups was verified with one-way ANOVA. Results:77.53% of the medical institutions had set up independent nosocomial infection management departments, and 87.30% of the institutions were qualified. 80% of the medical institutions had in place emergency plans for respiratory infectious diseases, but 98.05% of them had revised their plans during the pandemic, with an average of 10.85 newly added and revised provisions. Only 30.11% of emergency planed provide for clearly graded early warning.Conclusions:Efforts should be upgraded to develop an emergency prevention and control system for infection prevention and control in epidemics, and improve technical support for infection prevention and control in the system; to strengthen the clearly-graded early warning and graded responses in a scientific manner; and conduct regular drills, revise plan to ensure its applicability.