1. Pharmacokinetics and clinical significance of drugs for improving nonalcoholic fatty liver disease
Shen MA ; Yushuo LIU ; Ling GAO ; Shen MA ; Yushuo LIU ; Ling GAO ; Shen MA ; Yushuo LIU ; Ling GAO ; Shen MA ; Yushuo LIU ; Ling GAO ; Hui TANG ; Wenbin CHEN ; Ling GAO
Chinese Journal of Clinical Pharmacology and Therapeutics 2022;27(8):908-918
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease in China. There is no specific drug approved for marketing at home and abroad. At present, some adjuvant drugs are mainly used to improve the progress of the disease. Being familiar with and mastering the pharmacokinetic characteristics is very important for the selection and use of drugs. According to the characteristics of drug absorption, distribution, metabolism and excretion, reasonable drugs are selected to improve the therapeutic effect and reduce adverse reactions. Therefore, this paper reviews the pharmacokinetics and clinical significance of drugs commonly used to improve nonalcoholic fatty liver disease in hope of providing basis for clinical medication.
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