1.Effect of rehmaionoside A on cyclophosphamide induced leukopenia in mice
Zhen YU ; Jun WANG ; Gengsheng LI ; Yusheng WANG ;
Chinese Traditional and Herbal Drugs 1994;0(11):-
Object To observe the effects of rehmaionoside A on mice leukopenia models induced by cyclophosphamide. Methods Mice leukopenia models were prepared by ip cyclophosphamide and then treated with rehmaionoside A. The levels of body weight, peripheral hemogram, reticulocyte count, spleen index, bone marrow karyocyte count and contents of bone marrow DNA were determined. Results Rehmaionoside A could obviously raise the counts of white blood cell, red blood cell, platelet, reticulocyte and bone marrow karyocyte, contents of bone marrow DNA, and body weight of the leukopenia model. Conclusion Rehmaionoside A has apparent leukogenic and antianemic actions.
2.The prevention and treatment of unstable bladder after suprapubic prostatectomy by capsaicin instilled into the bladder combined with patient-controlled epidural analgesia
Hanguo JING ; Ruji SHI ; Zhen CHENG ; Huiqiu YAN ; Tengchun WANG ; Yusheng JLNG ; Lizhi HUO ; Yuxia ZHOU
Chinese Journal of Postgraduates of Medicine 2008;31(23):24-26
Objective To explore the effect of the prevention and treatment of unstable bladder after suprapubic prostaectomy by capsaicin instilled into the bladder preoperatively combined with patient-controlled epidural analgesia(PCEA)for benign prostatic hyperplasia(BPH).Methods Sixty patients with BPH underwent suprapubic prostatectomy under epidural anesthesia were randomly divided into control group (30 cases)and treatment group(30 cases),100 ml of 100 μmol/L capsaicin was instilled into the bladder preoperatively for 30 minutes combined with PCEA after operation in treatment group,the control group was only given PCEA.Observed the incidence and continuous time of unstable bladder after operation in two groups.Results Unstable bladder was found in 3 cases of treatment group and they were Ⅰdegree,12 cases happened unstable bladder in control group,3 cases Ⅰdegree,5 cases Ⅱdegree,3 cases Ⅲ degree,1 case Ⅳ degree.There was obvious significance between two groups (P<0.05).Conclusion Capsaicin instilled into the bladder combined with PCEA can cut off the reflex arc of detrusor contraction more completely and has obvious effect of decrease the incidence of unstable bladder after suprapubic prostatectomy and can be used widely.
3.Comparation of D_3 with D_2 lymphadenectomy for advanced right colon cancer
Yongbo HUANG ; Guangcheng LIU ; Zhen YUAN ; Jiansheng SHEN ; Qinghua ZHANG ; Guoqiang TAO ; Gangquan WU ; Yusheng ZHANG
Chinese Journal of General Surgery 1997;0(06):-
Objective To study the safety, reasonableness and feasibility of D 3 lymphadenectomy(LC) for advanced right colon cancer(ARCC). Methods 97 cases of ARCC were divided randomly into two groups: D 2.LC group (55cases) and D 3 LC group (42cases). The climical data between D 3 LC and D 2LC were compared. Results Comparing to D 2 LC,D 3 had higher operative invasive degree, but the incidence of postoperative complications did not increase, the ratio of the curable resection and the three-year and five-year survival rate after operation were significantly higher (88.1% and 73.8% vs 72.8% and 52.7%) (all P
4.Quality analysis of 2009 pandemic influenza A(H1N1) vaccines
Shuzhen LIU ; Ming SHAO ; Zhen CHEN ; Liyong YUAN ; Ping QIU ; Jianfeng WANG ; Zhifang YING ; Zhongyu HU ; Yusheng PEI ; Changgui LI
Chinese Journal of Microbiology and Immunology 2011;31(7):653-656
Objective To analyze the laboratory testing data of 2009 pandemic influenza A (H1N1) vaccines during lot release procedure, thus to know the overall quality status of this vaccines.Methods National Institutes for Food and Drug Control(NIFDC) carried out the laboratory test according to the specifications of each manufacture, and the results was analyzed and compared between manufacturer and NIFDC. Results 99.8% of vaccines batches were released by NIFDC, haemagglutinin contents were between 90% to 103 % of labeled values, and testing results slightly differ between manufactures and NIFDC,other items related to safety were all meet specifications. Conclusion The quality of H1N1 vaccines in China were satisfying, the lot release and independent test by NIFDC play important roles to ensure the vaccines' quality.
7.Expression of SleX in nasal epithelium with chronic rhinosinusitis.
Xuewei ZHU ; Dongdong ZHU ; Kewei SUN ; Yusheng WANG ; Zhen DONG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2008;22(20):917-919
OBJECTIVE:
To explore the expression of SleX in nasal epithelium in patients with chronic rhinosinusitis.
METHOD:
Nine nasal epitheliums from patients with chronic rhinosinusitis and 7 normal controls were stained with SleX antibody by immunohistochemistry, and its expression were analyzed.
RESULT:
Both nasal epithelial cells and neutrophils expressed SleX. Nearly 88.9% nasal epithelium from patients with chronic rhinosinusitis expressed SleX while 14.3% in normal control. Expression of SleX in nasal epitheliums from patients with chronic rhinosinusitis were higher than that in normal control. There were significant difference between two groups.
CONCLUSION
Nasal epithelium from patients with CRS is highly expressed SleX. It may involve the occurrence of chronic rhinosinusitis.
Adult
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Chronic Disease
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Female
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Humans
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Male
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Middle Aged
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Nasal Mucosa
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metabolism
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Neutrophils
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metabolism
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Oligosaccharides
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analysis
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Sinusitis
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metabolism
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Young Adult