Objective:To investigate the care burden of primary caregivers of young patients with brain tumor and to analyze the correlation between the care burden and social support level, in order to improve the mental health of caregivers, reduce the care burden and improve the quality of care for patients.Methods:Using the convenient sampling method, a total of 173 primary caregivers of young inpatients with brain tumor who were admitted to Department of Neurosurgery of Henan Provincial People's Hospital from December 2018 to November 2019 were selected as the research objects. General data questionnaire, Caregivers Burden Inventory (CBI) and Social Support Rating Scale (SSRS) were used to collect general information of caregivers, the care burden and the level of social support, Pearson correlation analysis of the correlation between care burden of the primary caregivers and social support level of young inpatients with brain tumor and use of the Logistic regression analysis to explore the influencing factors of care burden of the primary caregivers.Results:A total of 173 primary caregivers of young inpatients with brain tumor were investigated, and their CBI total score was (34.42±7.38) , which was at the medium burden level. Among them, a total of 13 (7.51%) had severe burden, 79 (45.66%) had moderate burden and 81 (46.82%) had mild burden. The total score of SSRS of caregivers was (43.61±8.46) , which was in the middle level of social support. Among them, a total of 71 (41.04%) had high level of social support, 92 (53.18%) had medium level of social support and 10 (5.78%) had low level of social support. Pearson correlation analysis showed that CBI score of caregivers was negatively correlated with SSRS score ( P< 0.05) . Logistic regression analysis showed that age, family monthly income per capita, daily care time, with or without a co-care, depression and social support level were the influencing factors of the caring burden of the caregivers of young inpatients with brain tumor ( P<0.05) . Conclusions:The primary caregivers of young patients with brain tumor generally have different levels of care burden, and their burden degree is closely related to the level of social support. Age, family monthly income per capita, daily care time, with or without a co-carer, depression and social support level are the main factors affecting the burden of caregivers. Clinical nurses should take corresponding measures for the factors affecting the care burden and relevant institutions should actively build a policy support system for the primary caregivers, so as to reduce the burden of caregivers and improve the quality of care.

Objective:To explore the correlations of neurological function recovery and intraoperative bone window parameters with intracranial pressure (ICP) changes at perioperative period in patients with large hemispheric infarction (LHI) after standard large bone flap decompression.Methods:Forty LHI patients accepted standard large bone flap decompression in Department of Neurosurgery, People's Hospital of Zhengzhou University from December 2020 to December 2023 were enrolled. ICP was measured before decompression, at the time of bone flap removal, during dural opening, and 24 h after decompression. Correlations of National Institutes of Health Stroke Scale (NIHSS), Extended Glasgow Outcome Scale (GOSE) and Glasgow Coma Scale (GCS) score changes, length and area of the bone window, bone window area/cranial bone area, infarct brain tissue volume/brain tissue volume with ICP changes were analyzed by Pearson's correlation. Length and area of bone window in patients with good neurological function recovery (NIHSS score decreased by≥5, GOSE score increased by≥3, or GCS score increased by≥3 before and after decompression) were calculated.Results:ICP at the time of bone flap removal, during dural opening, and 24 h after decompression was significantly lower than that before decompression ( P<0.05); ICP at the time of bone flap removal was higher than that at 24 h after decompression and during dural opening. Reduction between ICP before decompression and that during dural opening was more obvious than ICP reduction before and 24 h after decompression and ICP reduction before decompression and at the time of bone flap removal, with significant differences ( P<0.05). Postoperative NIHSS scores were significantly lower than preoperative ones ( P<0.05), and both postoperative GOSE and GCS scores were significantly higher than preoperative ones ( P<0.05). Decrease of NIHSS score, increase of GOSE and GCS scores before and after decompression were positively correlated with ICP reduction before and 24 h after decompression ( r=0.386, P=0.018; r=0.411, P=0.033; r=0.319, P=0.037); length and area of the bone window were positively correlated with ICP reduction before and 24 h after decompression ( r=0.461, P=0.028; r=0.536, P=0.034); bone window area/cranial bone area was positively correlated with ICP reduction before and 24 h after decompression ( r=0.438, P=0.027), while infarct brain tissue volume/brain tissue volume was negatively correlated with ICP reduction before and 24 h after decompression ( r=-0.371, P=0.031). Of the 40 patients, 25 had good neurological function recovery after decompression, with length of the bone window ranged 12.3-16.7 cm and area of the bone window ranged 54.5-91.9 cm 2. Conclusion:Standard large bone flap decompression can reduce ICP and improve prognosis in LHI patients; intraoperative bone window parameters are obviously correlated with ICP reduction before and 24 h after decompression; length of the bone window ranged 12.3-16.7 cm and area of the bone window ranged 54.5-91.9 cm 2 are suggested for decompression.