Objective:To investigate the status quo of mobile phone addiction, social anxiety, sleep quality, safe behavior and the influence of mobile phone addiction on safe behavior of nursing students in practice, so as to provide evidence for improving the safety behavior of nursing students in practice.Methods:A total of 700 nursing students from The First Affiliated Hospital of Zhengzhou University from March 1 to 20, 2023 were selected by cluster sampling method. A cross-sectional investigation was conducted using the general data questionnaire, the Smartphone Addiction Scale-Short Version, the Nurse Safety Behavior Scale, the Social Anxiety Scale and the Pittsburgh Sleep Quality Index.Results:A total of 678 valid questionnaires were collected, with an effective recovery rate of 96.9%. Among the 678 nursing students in practice, 87 were male and 591 were female, aged (21.25±1.16) years old. The scores of safety behavior, mobile phone addiction, social anxiety and sleep quality of 678 nursing students were (52.33±7.31), (28.21±9.86), (41.92±7.64) and (4.56±2.79) respectively. Mobile phone addiction had a statistically significant effect on the prediction of safety behavior ( β = - 0.178, P<0.01). Social anxiety had an intermediate effect between mobile phone addiction and safety behavior, and the indirect effect accounted for 25.5%. Sleep quality could buffer the influence of social anxiety on safety behavior ( β = 0.022, P<0.05). Conclusions:The safety behaviors of student nurses are good, and there are phenomena of mobile phone addiction and social anxiety. Nursing managers and educators can effectively manage the mobile phones of nursing studentsin practice, reduce their social anxiety and improve their sleep quality, so as to improve the safety behaviors of nursing students in practice and ensure the safety of patients.

Objective:To explore and analyze the application effects of multi-site Mini-clinical Evaluation Exercise (Mini-CEX) method in teaching of orthopedic nursing interns.Methods:From September 2019 to December 2019, a total of 97 nursing students who took an internship in 4 Orthopedic Wards of the First Affiliated Hospital of Zhengzhou University were selected as research objects. Among them, 45 nursing students who took an internship in the First Ward and the Second Ward of Orthopedics were set as the control group and other 52 nursing students who took an internship in the Third Ward and the Sixth Ward of Orthopedics were set as the observation group. The control group was given routine nursing instruction, while the observation group was given multi-site Mini-CEX method on the basis of the control group. Scores of all dimensions of Mini-CEX and scores of departmental rotation examination after the completion of teaching and the scores of teaching efficacy of teachers before and after the implementation of multi-site Mini-CEX method were compared between the two groups.Results:Scores of all dimensions and the total score of Mini-CEX of nursing interns in the observation group were higher than those in the control group, and the differences were statistically significant ( P<0.05) . The scores of theoretical assessment and practical operation of departmental rotation examination of nursing students in the observation group were higher than those of the control group, and the differences were statistically significant ( P<0.05) . After the implementation of multi-site Mini-CEX teaching program, the general teacher efficacy, personal teaching efficacy and total scores of nursing teachers were higher than those before the implementation, and the differences were statistically significant ( P<0.05) . Conclusions:Application of multi-site Mini-CEX method in surgical nursing practice teaching can improve clinical skills, comprehensive ability and learning interest of nursing students, and also help to improve the teaching efficacy of teachers, which is worthy of promotion and application.

Squamous cell carcinoma, which originates from squamous epithelium or tissue that undergoes squamous epithelial metaplasia, is one of the most common pathological types of solid human carcinoma. Although squamous cell carcinoma can occur in different anatomical locations, its pathogenesis has commonalities and distinctive features. Genetic mutations and abnormal expression of squamous differentiation markers, epigenetic modifications regulating target gene expression, and tumor microenvironment inducing immune escape of cancer cells are all involved in the development of squamous cell carcinoma. At present, great progress has been made in the research on the pathogenesis of squamous cell carcinoma. This article, combined with relevant research in recent years, reviews the pathogenesis of squamous cell carcinoma in terms of genome changes, epigenetic changes, non coding RNA regulation, tumor microenvironment changes and risk factor induction, so as to provide reference for the prevention and treatment of squamous cell carcinoma.