1.Long-Term Effects of Partial Axillary Dissection in Modified Radical Mastectomy of Breast Cancer
Chinese Journal of Bases and Clinics in General Surgery 2008;0(07):-
0.05).The incidence of upper limb edema and dysfunction was 4.2%(2/48) in PALD group and 16.0%(8/50) in TALD group(P0.05).Conclusion PALD may reduce upper limb dysfunction after operation in patients with stage Ⅰ and Ⅱ breast cancer,and does not increase prognostic risk.
2.A dynamic filter while using dual unipolar pulse excitation in digital ultrasound imapng system
International Journal of Biomedical Engineering 2009;32(2):95-98
Objective This paper analyzes the spectrum of ultrasonic echo and its change with depth when using dual unipolar pulse excitation.Methods According to the theory of matched filter,a group of aynmic filter was designed to ensure the near-field image resolution while maintaining the sensitivity of far-field image.Results This filter was accomplished in FPGA chip.Conclusion Higher image quality Can obtained applying this filter in the au-digital ultrasonic imaging system compared with those using constant filter.
3.Application and Immune Effect of Nutrison-5Fu on Perioperative Patients with Progressive Gastrointestinal Cancer
Lilin MA ; Yuquan CHEN ; Hongxing CHEN
Journal of Chinese Physician 2001;0(01):-
Objectives To investigate and evaluate the effect of Nutrison-5Fu on immune function of perioperative patients with progressive gastrointestinal cancer,and simultaneously we also recommended the methods of application of Nutrison-5Fu.Methods Seventy eight cases were equally divided at random into three groups,26 cases in each group.⑴Nutrison-5Fu group:the patients were treated with Nutrison-5Fu.⑵Chemotherapy group:the patients only received 5-Fu.⑶Control group:there were not any chemotherapy and immunetherapy during the perioperation.The values of CD 3,CD 4,CD 8 and NKCC were determined in all cases.Results Values of CD 3,CD 4,CD/CD 8 ratio and NKCC in most patients were distinctly low,but the condition rapid improved by giving them Nutrison-5Fu.On the contrary,the values declined further after chemotherapy alone.Conclusion The treatment of Nutrison-5Fu not only can repress the development of the tumor,but also can improve the dystrophic status and immune function of the patients with cancer.
4.Progress in megnetic nanobead preparation and application in bio-mediacal engineering
Zikai ZHAO ; Guohua HUI ; Yuquan CHEN
International Journal of Biomedical Engineering 2009;32(3):183-185,189
As a novel functional material with great application values, magnetic nanobead has been in fast development in recent years. Magnetic nanobead is provided with characteristics of beth polymeric and mag-netic particles, so it can be detected easily fi'om the medium and can be easily located since they can move di-rectionally when motivated by external electric field. The magnetic nanobead is widely used in biomedical engi-neering research due to its unique physical and chemical properties which simplify the complex experiments op-erations and shorten the testing period.
5.Advances in radio frequency identification sensor network
Hao YANG ; Xiaohe YANG ; Yuquan CHEN
International Journal of Biomedical Engineering 2006;0(06):-
Radio frequency identification sensor network, a technique integrating radio frequency identification (RFID) with wireless sensor network (WSN), is introduced. The basic structure of RFID sensor network is analyzed at first. Then components of RFID sensor and relevant supporting techniques including thin film battery, quartz crystal microbalance (QCM) and surface acoustic wave (SAW) are discussed. Research status and foregrounds of both domestic and international researches are introduced as well as applications in different fields.
6.THE EFFECTS OF COMPOUND ANTI-TUMOR GRANULES ON GROWTH INHIBITION AND EXPRESSION OF p53 AND PCNA IN MICE BEARING SARCOMA 180
Qingyong CHEN ; Yuquan WU ; Yongshen HE
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
To study the anti tumor effect of "Compound" granules on mice bearing sarcoma 180 and its possible mechanism, We observed the effect of "Compound" granules on tumor weight and expression of p53 and PCNA in mice bearing sarcoma 180 by means of immunohisto chemistry. After treatment with "Compound" anti tumor granules, anti tumor granules (Ⅰ,Ⅱ,Ⅲ) and CTX, the results showed that "Compound" granules and the other four drugs could inhibit sarcoma 180 growth to various extent, and the rates of inhibition were 20 31%, 6 56%, 15 0%, 19 06% and 30 3%, respectively. Meanwhile,we found the expression of p53 and PCNA in mice bearing sarcoma 180 was affected in various groups.It suggested that compound anti tumor granules had antitumor effect and its possible mechanism might be associated with inhibition the expression of mutate p53 and PCNA.
7.STUDY ON ICAM-1 EXPRESSION IN PERIPHERAL BLOOD OF ELDERLY PATIENTS WITH LUNG CANCER BEFORE AND AFTER CHEMOTHERAPY
Yuquan WU ; Qizhou SHEN ; Qingyon CHEN
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
To investigate the expression of ICAM 1 in peripheral blood lymphocyte in elderly patients suffering from lung cancer and the effect of chemotherapy on the expression of ICAM 1, peripheral blood ICAM 1 contents in 52 elderly patients with lung cancer were assayed with the method of immune flow cytometry before and after chemotherapy, and 32 normal elders and 35 patients with benign disease in lung served as controls. The results showed that the expression of ICAM 1 on lymphocyte in elders with lung cancer was significantly higher than that in patients with benign disease and normal controls. There was a significant difference between ICAM 1 expression in patients in stage Ⅲ, Ⅳ and that in patients in stage Ⅰ and Ⅱ. ICAM 1 in peripheral blood before chemotherapy was significantly higher than that after chemotherapy. It is suggested that the expression of ICAM 1 in peripheral blood lymphocyte might be useful to judge the efficacy of chemotherapy and evaluate prognosis in geriatric patients with lung cancer.
8.ROLE OF ADHESIVE MOLECULES IN MEDIATING HEMATOGENOUS METASTASIS OF DIFFERENT LUNG CARCINOMA CELL LINES AND THE REGULATION EFFECT OF TEA POLYPHENOLS
Qingyong CHEN ; Yuquan WU ; Xiaoxia JIANG
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Confocal microscope and flow cytometry were used to study the adhesion and the expression of adhesive molecules between different metastatic lung cancer cells and endothelial cells (EC) in vitro. Tea polyphenols (TP) were tested for their effect on tumor cell endothelial adhesion.The results showed that the adhesion and expression of CD44?CD54 were significantly higher in PG cells than those in D9 cells. Treatment of EC monolayers with LPS(0 5ug/ml) for six hours caused an increase in adhesion of PG to EC and adhesive molecules expression. TP could inhibit the adhesion of PG to EC and expressions of CD44 and CD54 in dose dependent manner. It suggested that adhesion molecules might play an important role in mediating the adhesion of lung carcinoma to EC and hematogenous metastasis; TP had an inhibitory effect on metastasis of lung cancer.
9.CLINICAL SIGNIFICANCE OF CD62P EXPRESSION IN PERIPHERAL BLOOD OF PATIENTS WITH NON-SMALL CELL LUNG CANCER BY FLOW CYTOMETRY
Qingyong CHEN ; Yuquan WU ; Li YAN
Medical Journal of Chinese People's Liberation Army 2001;0(10):-
To assess the expression of peripheral blood CD62P in patients with non-small cell lung cancer and its clinical significance, peripheral blood CD62P content in 75 patients with lung cancer was detected by immune-flow-cytometry. Among them 45 patients with lung cancer were subjected to comparison of the CD62P contents between pre-operation and post-operation, and comparison with those of 30 normal donors. The results showed that peripheral blood CD62P content in patients with lung cancer was significantly higher than that in normal con-trols(P