Surgical treatment of postinjection injury of peripheral nerve in 62 patients are reported, 50 patients were followed-up for 3 years in average. Neurolysis is an effective method in the treatment of such injuries with 64 percent of excellent and good result observed in this series. The results of operation were related to the degree of severity of nerve injury, timing of operation, and extent of adhesion of the injured nerve. The result of early operation is better than late operation.

Objective To establish the genetic and biochemical loci in Mesocricetus auratus and its albino mua-tant.Methods Protein isozyme cellulose acetate electrophoresis was used to determine the genetic and biochemical loci in Mesocricetus auratus and its albino mutant, using the genetic and biochemical loci of mice and rats.Results 25 biochemi-cal markers of Mesocricetus auratus and albino mutant were established, and polymorphism of their genetic biochemical loci was analyzed.Conclusions Polymorphism of biochemical loci is present in Mesocricetus auratus.Some differences exist between the genetic biochemical loci of Mesocricetus auratus and their albino mutant.These results laid the foundation for further study on genetic mechanism of albino mutation in Mesocricetus auratus.

OBJECTIVE To optimize the drying methods of Compound Scutellaria baicalensis extract powder. METHODS Compound S. baicalensis extract powder was prepared by atmospheric pressure drying， decompression drying and spray drying respectively， and high-performance liquid chromatography （HPLC） fingerprint of the extract powder was established. The physical fingerprint of the extract powder was established by 13 secondary indexes， such as particle size， particle size distribution and bulk density. HPLC fingerprints and physical fingerprints of 3 kinds of extract powders were compared by similarity evaluation method； through the conversion of the secondary indexes， five primary indexes of homogeneity， stacking， compressibility， fluidity and stability were calculated， and the physical properties of 3 kinds of extract powder were evaluated. The compressibility parameters of 3 kinds of extract powder such as index of parameter （IP）， index of parametric profile （IPP） and index of good compression （IGC） were calculated by the secondary index to evaluate the compression formability of the powder. RESULTS The similarity means of HPLC fingerprint of the extract powder obtained by atmospheric pressure drying， decompression drying and spray drying were 0.74， 0.90 and 0.94， respectively， and the similarity means of physical fingerprint were 0.74， 0.83 and 0.92， respectively. The overall similarity of spray drying extract powder was higher. The results of physical fingerprint analysis showed that the physical properties of the extract powder obtained by different drying methods were different. The 3 kinds of extract powder showed poor stability but good stacking. The homogenity and compressibility of extract powder by spray drying and decompression drying were better than those by atmospheric pressure drying， but the fluidity was worse than that by atmospheric pressure drying. The results of further compression formability analysis showed that the IP of spray drying extract powder was 0.54， IPP was 5.23， IGG was 5.03， and the spray drying extract powder could be directly pressed after adding a small amount of lubricant. CONCLUSIONS There are differences in HPLC and physical fingerprints of Compound S. baicalensis extract powder obtained by different drying methods. The spray drying extract powder possesses better Δ 基金项目 四川省公益性科研院所基本科研项目 （No.2022- 4-720） overall quality， which is more suitable for the drying of ＊第一作者副主任药师。研究方向：临床药学、药事管理、药物研 Compound S. baicalensis extract powder. 究。E-mail：hyptotti@163.com