1.A Tentative Study of the Countermeasures and Management of College Students with Mental Illness
Chinese Medical Ethics 1994;0(05):-
Mental illness is prone to occur during adolescence,thus it is one major threat to the health of college students.However,it remains to be a serious medical problem and heated research subject to effectively treat mental-disordered students in students' management affairs.This article carries out a systematic case analysis of mental-disordered students in Shandong University at Weihai from 1996-2008,and puts forwards concrete approaches and countermeasures of prevention and treatment for those specific students.It concludes that an early diagnosis of the illness,retaining of school rolls during medical treatment,good management of medical records,prevention of potential accidental injuries,and promising employment prospect prove to be conducive for the treatment and prevention of college students' mental illness.
2.Sanqi-Tongshu capsule's effect on hemodynamics in patients with acute cerebral infarction
International Journal of Traditional Chinese Medicine 2011;33(9):786-787
ObjectiveTo observe the effects of Sanqi-Tongshu capsule on the hemodynamics in patients with acute cerebral infarction (blood rheology, blood lipids), and to explore the clinical efficacy.Methods60 patients diagnosed of cerebral infarction by clinical and CT scan were randomized into a contrast group and a treatment group, with 30 patients in each group. The contrast group was treated with conventional western medicine the treatment group was treated with Sanqi-Tongshu capsule based on the contrast group. Hemorheology and blood lipid changes were observed before and after treatment. Results After the treatment,the treatment group's blood rheology [high shear whole blood (3.89±0.16) mpa·s, low-shear whole blood (8.12±0.06) mpa·s, erythrocyte aggregation index (1.164±0.24), erythrocyte rigidity index (3.53±0.40) ] and blood lipids [cholesterol (5.84± 0.92) mmol/L, triglycerides (1.54± 0.23) mmmmol/L, low-density lipoprotein (2.12 ± 0.54) mmol/L] showed statistical significance(all P<0.05)compared with the contrast group.ConclusionSanqi-Tongshu capsule can effectively improve the blood theology and lipid metabolism It is an effective drug for the treatment of acute cerebral infarction.
3.Clinical Observation on 60 Cases of Chronic Tourette's Disease Treated with Integrated Chinese and Western Medicine
Journal of Traditional Chinese Medicine 1993;0(01):-
0.05),and with significant differences as the TCM group and the WM group compared with TCM plus WM group(P
4.Clinical application value of combined detection of Hcy,FA,VitB12 and CA15-3 in breast cancer patients
Chinese Journal of Immunology 2014;(10):1408-1409,1412
Objective:To evaluate the alternation of homocysteine (Hcy),folic acid(FA),CA15-3 and vitaminB12(VitB12) in patients with breast cancer and explore the correlation of them.Methods:The levels of FA ,CA15-3 and VitB12 in serum of 55 breast cancer and 35 benign tumor of breast and 50 controls were measured by electro-chemiluminescence immunoassay ( ECLI ) , the Hcy levels were measured by colorimetric method.Results:Compared with the normal controls and benign tumor of breast cancer ,there were some significantly changes in breast cancer patients including Hcy ,CA15-3 increased and FA ,VitB12 reduced ( P<0.05 ) ,there were no significant differences in Hcy,FA,CA15-3,VitB12 levels between benign breast tumors and normal controls (P>0.05).Companied with TNM stage increased ,the levels of FA breast cancer groups decreased ,the levels of Hcy,CA15-3 increased.The correlation analysis showed that Hcy was negatively correlated with FA and VitB 12,(r=-0.341,r=-0.540),CA15-3 was negatively correlated with FA, CA15-3 was postively correlated with Hcy (r=0.378,r=-0.361).Conclusion: Serum Hcy,CA15-3,FA and VitB12 detection in patients with breast cancer are helpful in the severity judgment and regimen prognosis .
5.Antibacterial Effect in vitro of Sanhuang Shaoshangling after Preparation Technology Change
Sumei LI ; Baiqing GAO ; Yuping ZHAO
China Pharmacist 2016;19(9):1686-1688
Objective: To study the antibacterial activity in vitro of Sanhuang Shaoshangling on several common bacteria after changing the preparation process. Methods:Using the new technology of ethanol reflux extraction and water extraction, Sanhuang Sha-oshangling was prepared. A micro-broth dilution method was used to determine the minimum inhibitory concentration ( MIC) of San-huang Shaoshangling for escherichia coli, pseudomonas aeruginosa, staphylococcus aureus and type B paratyphoid salmonella after chan-ging the preparation process. The antibacterial effect of Sanhuang Shaoshangling prepared by the new and the old technology was com-pared, and the inhibition zone was detected by a paper strip method. Results:The antibacterial effect of Sanhuang Shaoshangling pre-pared by the new technology on escherichia coli, pseudomonas aeruginosa, staphylococcus aureus and type B paratyphoid salmonella was better than that of the products prepared by the old technology with the minimum inhibitory concentration ( MIC) of 16 μg·ml-1 , 16μg·ml-1 , 8 μg·ml-1 and 16 μg·ml-1 , respectively, while that of the product prepared by the old technology was 32 μg·ml-1 , 64 μg·ml-1 , 16 μg·ml-1 and 64 μg·ml-1 , respectively. Conclusion: The antibacterial effect of Sanhuang Shaoshangling after changing the preparation process is more significant, which shows certain clinical significance.
6.Systemic inflammatory response and the prognosis of esophageal cancer
Sijun ZHAO ; Ditian LIU ; Yuping CHEN
Journal of International Oncology 2016;43(4):315-318
Systemic inflammatory response has a major role in the development and progression of cancer,and increased systemic inflammatory response usually correlates with poorer survival.Recently the evaluation index of systemic inflammatory response including neutrophil-lymphocyte ratio,C-reactive protein,glasgow prognostic score,platelet-lymphocyte ratio.Several previous studies show that these indexes are the independent prognostic factors for esophageal cancer.Research on the systemic inflammatory markers may also be valuable for the clinical treatment and prognosis of esophageal cancer.
7.Neuroprotective effect of BMSCs on the lactacystin rats model of Parkinson's disease
Kezhong ZHANG ; Yuping JIANG ; Yanxin ZHAO
Journal of Clinical Neurology 1995;0(04):-
Objective To evaluate the protective role of bone marrow stromal cells (BMSCs) to lactacystin-Parkinson's disease (PD) rats.Methods BMSCs were obtained from adult male SD rats and were expanded, isolated and purified. BMSCs were harvested from 4 to 6 passage and used for transplantation. PD rats that expressed Lewy body and presented lateral rotation were made by injecting 8?g lactacystin into one side of substantia nigra compact part of rat with stereotaxic technique. The rats were transplanted with BMSCs labelled by Brdu by stereotaxic unilateral injection into striatum and transplanted with normal saline as control. The behavior changes of rats and the expression of BDNF, migration, differentiation of BMSCs were examined.Results 71.43% of the rats displayed significant improvement of contralateral behavior after BMSCs transplantation, however there was no change in control group. BMSCs were found in several areas of the brain including striatum, corpus callosum and contralateral cortex. The implanted BMSCs expressed BDNF but no tyrosine hydroxylase.Conclusion BMSCs may play a neuroprotective role in lactacystin-PD rats by secreting BDNF.
8.Effect of comprehend intervention on physical and intellectual development of one orphanage's infants
Congmin ZHAO ; Yuping ZHANG ; Min XI
Journal of Third Military Medical University 2003;0(17):-
Objective To observe the effect of comprehend intervention on physical and intellectual development of homeless infants.Methods Forty-eight infants aged 8 to 9 months from an orphanage of Chongqing were randomly divided into control group and treatment group.The treatment group received swim,early training and massage every day.All infants were assessed by means of Gesell Development Scale before intervention and one month after intervention.Results Compared with that of the control group,the treatment group's scores significantly improved in all four ergoregion(P
9.The clinical research to diagnose ovarian endometrial cyst by comprehend evaluation
Junli LIU ; Xuan ZHAO ; Yuping LI
Cancer Research and Clinic 2007;19(z1):63-65,67
Objective To explore the clinical diagnositic code(CDC)in ovarian endometrial cysts (OEC).Methods 218 cases of pelvic masses were investigated by use of symptoms,signs,B mode sonography and CA125.172 cases were diagnosed with OEC out of 218 cases,While 46 cases were ruled out by combination exploratory laparotomy and laparoscopy.Meanwhile we compared it with revisional american fertility society(r-AVS)including diagnosis and staging.Results The operation results of 218 cases were compared with the results of CDC and its Diagnositic Sensitiveness;Specificness;Positive predictive value;Negative predictive value;Diagnositic accordance rate as well as Diagnositic index of CDC were 96.4%,79.6%.93.0%,90.0%,91.7% and 73.4% respectively(χ2=127.818,P<0.001).Further more,172 cases of OEC which diagnosed with CDC were further subdivided into three stages as 1,2,3 according to its score,mild;moderate;heavy and this stage category were compared with the category of AFS(Ⅰ-Ⅱ,Ⅲ,Ⅳ),the Diagnositic accordance rate of two categories were 95.6%,95.6% and 83.0% respectively,No significant difference were found in Var.mitis and medium-sized(χ2=0,P>0.05).but the Medium-sized and Gravis tape was significance(χ2=4.472,P<0.05).Conclusion CDC has a better coincidence with operation in the diagnosis of OEC which can be used in the non-traumatic diagnosis and staging of OEC in clinic.
10.The clinical efficiency of the delayed extubation for patients with myasthenia gravis after the extubation
Yaoguang JIANG ; Ruwen WANG ; Yuping ZHAO
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(04):-
0.05) in the two periods,the ratio of tracheostomy was significantly higher (P