2.The independent predictors of 3-day mortality in patients with systemic inflammatory response syndrome in emergency department
Chinese Journal of Emergency Medicine 2009;18(8):864-867
Objective To study the independent predictors of 3-day mortality of patients with systemic in-flammatory response syndrome(SIRS) in emergency department. Method From Dec 2006 to Sep 2007, 640 pa-tients with SIRS admitted to emergency department were enrolled. Those died within one hour were excluded. Ev-ery patient was examined on plasma B-type natriuretie peptide (BNP) level and serum cardiac Troponin Ⅰ (cTNI) level. Early warning score (EWS) was calculated. Rank test was used to compare the difference of BNP,cTNI and EWS between survivors and non-survivors. Logistic regression analysis was used to determine the independent pre-dictors for death and receiver operator characteristic curve was used to determine the cutoff values. Results The mean levels of age, BNP, cTNI and EWS of patients died in 3 days were 73.5(65~80),468.5 pg/mL(161.5~1862.5 pg/mL),0.37 ng/mL(0.07~2.61 ng/mL) and 6(5~9), respectively. In survivors, the mean levels of age, BNP, cTNI and EWS were 71(60~77), 239 pg/mL(56.3~783.8 pg/mL), 0.07 ng/mL(0.03~0.26 ng/mL)and 4(3~6), respectively. There were significant difference in age, BNP, cTNI and EWS between two groups (P < 0.05). Age ≥ 76, BNP ≥ 115 pg/mL, cTNI ≥ 0.135 ng/mL and EWS ≥ 6 were independent predic-tors of death. Conclusions Levels of BNP,cTNI and EWS were predictors of death in SIRS patients during emer-gency department stay.
3.Comparison of the resistin levels between Mongolian and Han population in patients with metabolic syndrome and its related factors
Chinese Journal of Primary Medicine and Pharmacy 2013;20(11):1608-1610
Objective To explore the differences of resistin level between Mongol and Han population in patients with metabolic syndrome and to analyze its related factors.Methods According to the diagnostic criterion of metabolic syndrome,30 patients with metabolic syndrome in Mongol population (group 1) and 28 patients with metabolic syndrome in Han population(group 2) were randomly selected from health examination population.Radioimmunoassay kit was used to examine the serum resistin level in patients with metabolic syndrome.At the same time,their weight,height,blood pressure,blood glucose,blood lipid [high density lipoprotein (HDL),low density lipoprotein (LDL),total cholesterol (TC),glycerin three greases (TG)],blood uric acid (UA),leptin,insulin were measured,and body mass index(BMI) and insulin resistance index(HOMA-IR) were counted and compared.Results There were significant differences in systolic pressure,leptin,resistin,blood insulin and HOMA-IR between the two groups(all P < 0.05).There were no significant differences in age,diastolic pressure,BMI,HDL,LDL,TG,TC,UA and blood glucose between the two groups(all P >0.05).The increase of resistin level in group 1 was associated with UA,systolic pressure and HOMA-IR(r =0.357,0.427,0.582,all P < 0.05).Conclusion The serum resistin level of patients with metabolic syndrome in Mongol population is correlated with UA,systolic pressure and insulin resistance index,and maybe play an important role in the development of metabolic syndrome.
4.Treatment opportunity for early childhood caries
Journal of Practical Stomatology 2016;32(3):422-425
Objective:To estimate the effect of treatment opportunity for severe caries in primary molars on child dental fear and dent-al behavior.Methods:288 children aged 3 -6 years with primary molars caries were included on the first visit.The children in the ex-perimental group(n =144),with obvious clinical symptom,were initiative to see a dentist.Those in control group(n =144)without evident symptom were found with caries in conventional dental examination.The change of the children fear before and after the first treatment was assessed by MCDASf within the first week,the change of children's clinical behavior in their first and return visit was esti-mated by Venham Clinical Anxiety and Cooperation Behavior Measurement Scale.Data was statistically analyzed.Results:After the first treatment and during the return visit,the MCDASf average score of the experimental group was decreased(P <0.05),that of the control group was not(P >0.05).On their return visit,the behavior of the 2 groups was similar (P >0.05),and which was ameliora-ted in the experimental group during their own first and return visit,compared with the control group(P <0.05).Conclusion:Treat-ment of severe caries before acute symptom arising in young children may alleviatie the child dental fear.
5.Determination of Triptolide in Compound Tripterygium Wilfordil Syrups by HPLC
China Pharmacist 2014;(2):316-318
Objective:To establish a method for the content determination of triptolide in compound tripterygium wilfordil syrups by HPLC. Methods:The samples were analyzed on a Diamonsil C18 column(150 mm × 4. 6 mm,5μm), the mobile phase consisted of methanol and water (46∶54), the flow rate was 1. 0 ml·min-1, the detection wavelength was 224 nm, and the column temperature was kept at 30℃, and the injection volume was 10 μl. Results: The linear range of triptolide was 5. 66-33. 96 μg · ml-1 ( r =0. 999 8), and the average recovery was 99. 35% with RSD of 1. 02%(n=9). Conclusion:The method is simple and sensitive with good repeatability, and can be used to control the quality of triptolide in compound tripterygium wilfordil syrups.
6.Analysis of cancer incidence among 89906 person-times physical examination
Chinese Journal of Primary Medicine and Pharmacy 2013;20(19):2885-2886
Objective To reveal the characteristics of cancer incidence in subjects of routine physical examination in Huhehot,and provide a rehable basis for cancer prevention and health guidance.Methods The medical data of cancer incidence were analyzed in the first affiliated hospital of Inner Mongolia medical from September 2009 to September 2011.Results A total of 113 patients with malignant tumors were found,with the detection rate of 1.3%.The incidence of lung cancer was the highest (33.6%),followed by the incidence of Thyroid cancer (14.2%).Conclusion Routine medical examination is helpful to detect early stage malignant tumors.The thyroid should be detected as a priority one in the physical examination;the elderly should be checked as important crowd.
7.The effectiveness of XueBiJing injection in therapy of sepsis: a multicenter clinical study
Chinese Journal of Emergency Medicine 2013;22(2):130-135
Objective To evaluate the effectiveness and safety of Xuebijing (XBJ) injection in therapy of sepsis.Methods It is a prospective,randomized controlled trial conducted in multicenter.Totally 731 patients with sepsis were enrolled from January to December 2011 at 37 centers and randomly (random number) separated into the XBJ group (n =392) and the control group (n =339).Basic therapy was adoptd in the both groups,but XBJ injection was additionally used in the XBJ group.The effectiveness of XBJ injection was evaluated by comparing the differences of MEDS score,APACHE Ⅱ score,DIC score,SOFA score,coagulation parameters,duration of mechanical ventilation and antibiotic therapy between the two groups.The influence on the outcome of XBJ injection was assessed by mortalities of 28-day and 90-day.The side-effects of XBJ injection were recorded.Results The score of each system and the abnormal rates of coagulation parameters were significantly higher in the XBJ group than in the control group at admission (P < 0.05).After combined treatment of XBJ injection and basic therapy,the score values of the XBJ group decreased distinctly,and the differences of pre-therapy and post-therapy in the two groups had statistical significance (P<0.01).The abnormal rates of coagulation parameters in the XBJ group decreased after therapy.The 90-day mortality of the XBJ group was lower than the control group (P < 0.05).No severe side-effects were found during study.Conclusions This study proved that the severity of sepsis can be alleviated by XBJ injection.Meanwhile,the organ function and the coagulation status can be protected,and then the prognosis can be improved.The safety of XBJ injection was good.
8.The differences and its related factors of leptin levels between Mongol and Han population
Clinical Medicine of China 2013;29(11):1144-1147
Objective To investigate the differences of leptin (LEP) between Mongol and Han population with metabolic syndrome (MS) and its related factors.Methods According to the diagnostic criterion of MS,291 people with MS were selected as subjects,of which,146 were Han nationality(A group) and 145 were Mongol(B group).Radioimmunoassay kit was used to measure the serum leptin level.At the same time,the indices including weight,height,blood pressure,blood glucose,blood lipid,Serum uric acid (sUA),insulin (Fins),body mass index (BMI) and insulin resistance index (HOMA-IR) were measured.Results The following indices in B group including fasting plasma glucose (FPG),Low-density lipoprotein cholesterol (LDL-C),leptin,blood insulin,insulin resistance index were (6.2 ± 1.5) mmol/L,(3.1 ± 0.8) mmol/L,(4.3 ± 2.0) μg/L,(22.4-± 16.0) mU/L and (6.5 ± 0.5) respectively,significantly differed from that of A group ((6.7 ±1.7) mmol/L,(2.7 ±0.7) mmol/L,(3.4 ± 1.5) μg/L,(18.8 ±14.0) mU/L,(4.7 ±3.6)respectively;t =2.04,2.84,3.47,2.18,4.82 ;P < 0.01 or P < 0.05).There was no significant difference in terms of age((46.9 ±9.8) vs.(46.3 ± 8.4)),systolic blood pressure (SBP) ((146.8 ± 17.0) mm Hg vs.(149.1 ±19.2) mm Hg),diastolic blood pressure (DBP) ((90.5 ± 11.6) mm Hg vs.(92.5 ± 13.1) mm Hg),BMI ((27.4 ± 2.9) kg/m2 vs.(27.9 ± 3.2) kg/m2),total cholesterol (TC) ((5.5 ± 1.0) mmol/L vs.(5.5 ±0.9) mmol/L),triacylglycerol (TG) ((2.3 ± 1.4) mmol/L vs.(2.3 ± 1.4) mmol/L),high density lipid cholesterol (HDL-C) ((1.3 ±0.3) mmol/L vs.(1.2 ±0.4) mmol/L),and sUA (((320.7 ±93.6)μmol/L) vs.(308.7 ±86.9) μmol/L) between the patients with metabolic syndrome in Mongol population and in Han population(t =0.47,0.90,1.15,1.15,0,0,1.00,0.94 respectively,P > 0.05).The increase of leptin level in the patients with metabolic syndrome in B group was associated with blood glucose,blood insulin and insulin resistance index (r =0.108,0.146,0.183 ; P < 0.05).BMI,blood insulin and insulin resistance index may be the factors due to the higher of serum leptin levels.Conclusion The serum leptin of patients with metabolic syndrome in Mongol population are correlated with blood glucose,blood insulin and insulin resistance index,which plays an important role in the development of metabolic syndrome.
9.Pulmonary Hypertension in Pregnancy:Analysis of 53 Case
Journal of Medical Research 2006;0(09):-
Objective To analyze the pregnancy outcomes and measures to prevention and cure for pregnancy women with pulmonary hypertension.Methods Clinical data of 40 women with pulmonary hypertension were analyzed and they were divided into three groups on the basis of Doppler transthoracic echocardiography detections.Results(1)The proportions of rheumatic heart disease and congenital heart disease were 22.64% and 45.38%;8 cases appeared with the perinatal heart disease and 5 cases' hearts structure were normal.(2)49 cases applied cesarean section and 2 delivery naturally.2 women were induction of labour in second trimester.In midrange and severity groups,prematurity and small gestational age were significently higher than those of gentle group.(3)3 women died of congestive heart failure and pulmonary embolism.6 women were treated by SICU and physician because of serious illness.Conclusion Women with midrange and severely pulmonary hypertension should avoid pregnancy.Pregnant women with pulmonary hypertension needed monitor closely and being treated with pulmonary vasodilator added decoagulant would improve outcomes of mather and infant.
10.Orienting Independent Local medical colleges from the Perspective of Scientific Development
Chinese Journal of Medical Education Research 2005;0(06):-
The present paper analyses the current macro-setting independent regional medical colleges may face when setting their orientation.From the perspective of scientific development,the paper describes the principles independent regional medical colleges must follow in pursuit of their orientation: classifying accurately when orienting,service targeting correctly,considering both the function and benefit,and highlighting the advantages of the school.The paper also illustrates the connotation of the orientation of independent regional medical colleges in three respects: goal of schooling,type and level of the school,standard and characteristics of the school.