1.Prevalence pilot study on population who was born in 1959~1961 years in Chongqing
Journal of Chongqing Medical University 2007;0(11):-
Objective:Analysis health condition and dangerous factor to people who was born in 1959~1961.study the stratification chronic diseases associated risk factors.Methods:Collecting investigated objective average situation about health condition index and probably dangerous effection with questional paper and physical check-up.according ?2 test and non-prerequisite logistic regression analysis.Results:The three groups BMI BG &BP abnormorly rate hasn’t exist statistically valid significance difference.Conclusion: Although research results couldn’t prove those relationship directly between early life period malnutrition and organism situation in adulthood,retrospectie cohort study further.
2.Application of peer education teaching methods in nutrition propaganda and education
Chinese Journal of Medical Education Research 2003;0(04):-
In order to fit new plot proposed by medical education reform,by integrating interrelated resources,the author introduced peer education into the whole process of nutrition propa-ganda and education to promote the development of the whole social health education.
3.How to better increase the publication rate of medical paper from the perspective of editing
Chinese Journal of Medical Education Research 2006;0(08):-
With the experience of editing to summarize general or part requirements of the medical paper writing and to indicate the relative points for attention before contribution.
4.Value of critical care medicine scoring systems and procalcitonin in evaluation of severe multiple trauma
Xiangwei WU ; Yunliang CUI ; Yonghua XU ; Jun GUAN ; Wenfang LI ; Dechang CHEN
Chinese Journal of Trauma 2012;28(4):291-295
Objective To compare the value of acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ ),sequential organ failure assessment (SOFA) and procalcitonin (PCT) in assessment of severe multiple trauma. Methods A retrospective study was carried out on clinical data of patients with severe multiple trauma who were admitted to ICU from July 1 st 2010 to October 31 st 2011.PCT detection,APECHE Ⅱ and SOFA scoring were routinely performed for all the patients within 24 hours,and were performed again one week later for the patients who were complicated with sepsis within one week.Results The score of APACHE Ⅱ and SOFA in septic shock group was higher than that in severe septic and septic groups (P <0.01 ),while PCT level among septic,severe septic and septic shock groups had no statistical difference (P > 0.05).To determine the predicting accuracy of APECHE Ⅱ score,SOFA score and PCT,receiver operating characteristic curve (ROC) was constructed.The areas under the curve (AUC) for APECHE Ⅱ score,SOFA score and PCT in predicting the emergence of sepsis on admission was 0.615,0.663 and 0.160 respectively.AUC for APECHE Ⅱ score,SOFA score and PCT in predicting the occurrence of death among the severe multiple trauma patients on admission was 0.576,0.571 and 0.619 respectively.AUC for APECHE Ⅱ,SOFA and PCT in predicting the death of patients complicated with sepsis at one week after admission was 0.746,0.837 and 0.600 respectively. Conclusions Among the APACHE Ⅱ score,SOFA score and PCT,APACHE Ⅱ and SOFA score are better than PCT in assessing the infection severity of sepsis.SOFA score is the best in predicting the occurrence of sepsis,while PCT is the worst.PCT is the best in predicting the occurrence of death of severe multiple trauma patients,while SOFA score is the worst.SOFA score is better than APACHE Ⅱ score and PCT in predicting the occurrence of death of the patients complicated with sepsis.
5.Progress of myeloid-derived suppressor cells in hematological tumors
Yejing ZHU ; Yunliang HAO ; Yun GUAN
Journal of Leukemia & Lymphoma 2020;29(11):698-701
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that can regulate the immune response. They play an important role in the formation and progression of tumors and can suppress immune response in infections and inflammatory diseases. In recent years, MDSC have attracted a lot of attention in the field of tumor immunology, especially in solid tumors, but little is known about the role in hematological tumors. In this paper, the characteristics, functions and related clinical researches of MDSC in hematological tumors including multiple myeloma (MM), lymphoma, leukemia, and myelodysplastic syndrome (MDS) will be summarized to provide new ideas for the treatment of hematologic system tumors.