PURPOSE: The purpose of the study was to identify the prevalence, risk factors and clinical meanings of geriatric foot problems and to suggest implications for the future. METHODS: One hundred eighty nine elderly aged 60 and over from institution as well as community were investigated for their foot conditions by means of a questionnaire including general characteristics, self care capacity, risk factors, foot problem checklist, X-ray, podoscopy and foot scan. Descriptive statistics and chi-square-test was performed as appropriate utilizing SPSS version 14. Less than .05 of p-value was adopted as statistical significance level. RESULTS: All subjects had at least one kind of foot problem and the most prevalent ones were nail problems, foot deformities in order. Prevalence of foot pain and edema was relatively low. CONCLUSION: Foot problem in elderly is prevalent and geriatric foot is expected to emerge as one of the most important problems in the geriatric field. Therefore strategies to deal with geriatric foot should be developed and practiced for better quality of life in later life.
Aged ; Aged, 80 and over ; Female ; Foot Deformities/epidemiology ; Foot Diseases/*epidemiology/etiology ; Geriatric Assessment ; Health Status ; Humans ; Male ; Middle Aged ; Nails, Malformed/epidemiology ; Quality of Life ; Questionnaires ; Republic of Korea ; Risk Factors ; Self Care

PURPOSE: This study examined the effects of a mobile app-based program to reduce the dietary sugar intake according to the stages of the behavioral change in dietary sugar reduction in female college students. METHODS: The program used in this study can monitor the dietary sugar intake after recording the dietary intake and provide education message for the reduction of dietary sugar intake. In an eight-week pre-post intervention study, 68 female college students were instructed to record all the food they consumed daily and received weekly education information. At pre-post intervention, the subjects were asked to answer the questionnaire about sugar-related nutrition knowledge, sugar-intake behavior, and sugar-intake frequency. For statistical analysis, ANOVA and a paired t-test were used for comparative analysis according Precontemplation (PC), Contemplation ·Preparation (C ·P), and A ·M (Action ·Maintenance) stage. RESULTS: Significant differences were observed in the frequency of snacking, experience of nutrition education, and preference for sweetness according to the stages of behavior change in dietary sugar reduction. After finishing an intervention, the sugar-related nutrition knowledge score was increased significantly in the stages of Precontemplation (PC) and Contemplation ·Preparation (C ·P). The score of the sugar intake behavior increased significantly in all stages. The intake frequency of chocolate, muffins or cakes, and drinking yogurt decreased significantly in the PC stage and the intake frequency of biscuits, carbonated beverages, and fruit juice decreased significantly in the C ·P stage. Subjects in the PC and C ·P stages had an undesirable propensity in nutrition knowledge, sugar-intake behavior, and sugar-intake frequency compared to the A ·M stage, but this intervention improved significantly their nutrition knowledge, sugar-intake behavior, and sugar-intake frequency. CONCLUSION: This program can be an effective educational tool in the stages of PC and C ·P, and is expected to further increase the usability and sustainability of mobile application if supplemented appropriately to a health platform program.
Cacao ; Carbonated Beverages ; Drinking ; Education ; Female ; Fruit and Vegetable Juices ; Humans ; Mobile Applications ; Snacks ; Yogurt

High-intensity interval training (HIIT), characterized by alternating intense exercise with short recovery periods, has emerged as an effective and time-efficient approach for diabetes management. HIIT is particularly recommended for individuals who are physically capable and have limited time, as per guidelines from the Korean Diabetes Association (KDA) and the American Diabetes Association (ADA). Studies indicate that HIIT can enhance aerobic capacity, reduce insulin resistance, and improve glycemic control while potentially decreasing cardiovascular risks, such as high blood pressure and lipid imbalances. Moreover, HIIT may help mitigate diabetes-related complications by improving vascular function and insulin sensitivity. However, HIIT carries certain risks, such as episodes of hyperglycemia, hypoglycemia, and an increased risk of musculoskeletal injury, particularly in older adults or those with lower fitness levels. Therefore, it is crucial that HIIT regimens be individualized and guided by healthcare professionals to ensure safe and effective integration into diabetes management.

High-intensity interval training (HIIT), characterized by alternating intense exercise with short recovery periods, has emerged as an effective and time-efficient approach for diabetes management. HIIT is particularly recommended for individuals who are physically capable and have limited time, as per guidelines from the Korean Diabetes Association (KDA) and the American Diabetes Association (ADA). Studies indicate that HIIT can enhance aerobic capacity, reduce insulin resistance, and improve glycemic control while potentially decreasing cardiovascular risks, such as high blood pressure and lipid imbalances. Moreover, HIIT may help mitigate diabetes-related complications by improving vascular function and insulin sensitivity. However, HIIT carries certain risks, such as episodes of hyperglycemia, hypoglycemia, and an increased risk of musculoskeletal injury, particularly in older adults or those with lower fitness levels. Therefore, it is crucial that HIIT regimens be individualized and guided by healthcare professionals to ensure safe and effective integration into diabetes management.

High-intensity interval training (HIIT), characterized by alternating intense exercise with short recovery periods, has emerged as an effective and time-efficient approach for diabetes management. HIIT is particularly recommended for individuals who are physically capable and have limited time, as per guidelines from the Korean Diabetes Association (KDA) and the American Diabetes Association (ADA). Studies indicate that HIIT can enhance aerobic capacity, reduce insulin resistance, and improve glycemic control while potentially decreasing cardiovascular risks, such as high blood pressure and lipid imbalances. Moreover, HIIT may help mitigate diabetes-related complications by improving vascular function and insulin sensitivity. However, HIIT carries certain risks, such as episodes of hyperglycemia, hypoglycemia, and an increased risk of musculoskeletal injury, particularly in older adults or those with lower fitness levels. Therefore, it is crucial that HIIT regimens be individualized and guided by healthcare professionals to ensure safe and effective integration into diabetes management.

High-intensity interval training (HIIT), characterized by alternating intense exercise with short recovery periods, has emerged as an effective and time-efficient approach for diabetes management. HIIT is particularly recommended for individuals who are physically capable and have limited time, as per guidelines from the Korean Diabetes Association (KDA) and the American Diabetes Association (ADA). Studies indicate that HIIT can enhance aerobic capacity, reduce insulin resistance, and improve glycemic control while potentially decreasing cardiovascular risks, such as high blood pressure and lipid imbalances. Moreover, HIIT may help mitigate diabetes-related complications by improving vascular function and insulin sensitivity. However, HIIT carries certain risks, such as episodes of hyperglycemia, hypoglycemia, and an increased risk of musculoskeletal injury, particularly in older adults or those with lower fitness levels. Therefore, it is crucial that HIIT regimens be individualized and guided by healthcare professionals to ensure safe and effective integration into diabetes management.

High-intensity interval training (HIIT), characterized by alternating intense exercise with short recovery periods, has emerged as an effective and time-efficient approach for diabetes management. HIIT is particularly recommended for individuals who are physically capable and have limited time, as per guidelines from the Korean Diabetes Association (KDA) and the American Diabetes Association (ADA). Studies indicate that HIIT can enhance aerobic capacity, reduce insulin resistance, and improve glycemic control while potentially decreasing cardiovascular risks, such as high blood pressure and lipid imbalances. Moreover, HIIT may help mitigate diabetes-related complications by improving vascular function and insulin sensitivity. However, HIIT carries certain risks, such as episodes of hyperglycemia, hypoglycemia, and an increased risk of musculoskeletal injury, particularly in older adults or those with lower fitness levels. Therefore, it is crucial that HIIT regimens be individualized and guided by healthcare professionals to ensure safe and effective integration into diabetes management.

There have been few reports on chromosomal abnormalities in secondary hemophagocytic lym-phohistiocytosis (HLH) including Epstein-Barr virus-associated HLH (EBV-HLH). Clonality of HLH can be determined by karyotypic analysis, T-cell receptor or IgH rearrangement studies, and EBV genome terminal repeat investigation. Chromosome analysis in EBV-HLH is the most important tool currently available for assessment of case-by-case prognosis. We report a case of fatal EBV-HLH with clonal karyotype abnormality. A 57-year-old man was admitted with persistent high fever and hepatosplenomegaly. Laboratory data revealed pancytopenia, hypofibrinogenemia, coagulation abnormalities, and marked abnormalities of liver function tests. EBV-DNA was detected in the bone marrow by PCR. The bone marrow studies showed mature, benign-looking histiocytic hyperplasia with prominent hemophagocytosis and clonal chromosomal abnormality. Although the patient was treated with immunochemotherapy and antibiotics, he died of disseminated intravascular coagu-lopathy and sepsis. Considering this fatal clinical course, it is important to take intensive therapeutic measures if karyotype abnormality is noted in the treatment of EBV-HLH cases.
Anti-Bacterial Agents ; Bone Marrow ; Chromosome Aberrations ; Fever ; Genome ; Herpesvirus 4, Human ; Humans ; Hyperplasia ; Karyotype* ; Liver Function Tests ; Lymphohistiocytosis, Hemophagocytic* ; Middle Aged ; Pancytopenia ; Polymerase Chain Reaction ; Prognosis ; Receptors, Antigen, T-Cell ; Sepsis ; Terminal Repeat Sequences

The CD56 antigen is a cell adhesion molecule and its expression on tumor cells is thought to play a role in CD56-positive lymphomas and leukemias with unusual sites of involvement. As to chronic myelogenous leukemia (CML) and related blastic crisis, CD56 expression is not generally considered as a part of the CML phenotype and has rarely been reported in CML and other chronic myeloproliferative dirsorders (CMPD). We reported a case of CML expressing the CD56 antigen on the CD34-negative myeloid cells presented with extramedullary granulocytic sarcoma and examined the CD56 reactivity on bone marrow biopsy sections in 9 patients with CMPD. To assess the abnormal expression of the CD56 antigen on myeloid and progenitor cells from CMPD, immunohistochemical staining and flow cytometric analysis were performed on bone marrow biopsy sections and aspirate specimens, respectively. Of nine patients with CMPD, a case of CML in blastic crisis with extramedullary granulocytic sarcoma showed an abnormal expression of CD56 on CD34-negative myeloid cells. The expression of CD56 on CML myeloid elements seems to represent an aberrant phenomenon that could affect the pattern of tumor cell dissemination.
Antigens, CD56 ; Biopsy ; Bone Marrow ; Cell Adhesion ; Humans ; Leukemia ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive* ; Lymphoma ; Myeloid Cells* ; Phenotype ; Sarcoma, Myeloid ; Stem Cells

When treating trauma patients with severe hemorrhage, massive transfusions are often needed. Damage control resuscitation strategies can be used for such patients, but an adequate fresh frozen plasma: packed red blood cell (FFP:PRBC) administration ratio must be established. We retrospectively reviewed the medical records of 100 trauma patients treated with massive transfusions from March 2010 to October 2012. We divided the patients into 2 groups according to the FFP:PRBC ratio: a high-ratio (> or =0.5) and a low-ratio group (<0.5). The patient demographics, fluid and transfusion quantities, laboratory values, complications, and outcomes were analyzed and compared. There were 68 patients in the high-ratio and 32 in the low-ratio group. There were statistically significant differences between groups in the quantities of FFP, FFP:PRBC, platelets, and crystalloids administered, as well as the initial diastolic blood pressure. Bloodstream infections were noted only in the high-ratio group, and the difference was statistically significant (P=0.028). Kaplan-Meier plots revealed that the 24-hr survival rate was significantly higher in the high-ratio group (71.9% vs. 97.1%, P<0.001). In severe hemorrhagic trauma, raising the FFP:PRBC ratio to 0.5 or higher may increase the chances of survival. Efforts to minimize bloodstream infections during the resuscitation must be increased.
Acute Lung Injury/epidemiology/etiology ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bacterial Infections/epidemiology ; *Blood Transfusion/adverse effects ; *Erythrocyte Transfusion/adverse effects ; Female ; Hemorrhage/etiology/*prevention & control ; Hospital Mortality ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Patients ; Respiratory Distress Syndrome, Adult/epidemiology/etiology ; Resuscitation ; Retrospective Studies ; Wounds and Injuries/complications/mortality/*therapy ; Young Adult