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Eosinophilic esophagitis (EoE) with adults, as a new disease emerging during the last decade, is a clinicopathologic disorder of the esophagus characterized by a dense esophageal eosinophilic infiltration and typical esophageal symptoms. As numerous studies about EoE had been reported during last several years, updated consensus of EoE was reported in July 2011. The conceptual definition of EoE is coming. EoE is defined as a chronic, immune/antigen-mediated esophageal disease characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominat inflammation. Other important addition is genotyping feature that implicates thymic stromal lymphopoietin genes or filagrrin as EoE susceptibility genes. The majority of patients has the concurrent allergic disease, especially food or aeroallergen sensitization. Main therapeutic options include topical steroids and dietary modification. Recent issues of EoE include a new concept for proton pump inhibitor-responsive esophageal eosinophilia that it should be excluded to diagnose EoE.
Diet ; Endoscopy, Gastrointestinal ; Eosinophilic Esophagitis/*diagnosis/pathology/therapy ; Esophagus/surgery ; Humans ; Hydrogen-Ion Concentration ; Hypersensitivity/immunology ; Immunoglobulin E/metabolism ; Proton Pump Inhibitors/therapeutic use ; Steroids/therapeutic use

7.Effect of Amitriptyline in Patients with Functional Dyspepsia.

Yunju JO

The Korean Journal of Gastroenterology 2015;66(4):245-247

8.Decreased Eradication Rates of Helicobacter pylori and Problem Solving.

Yunju JO

The Korean Journal of Gastroenterology 2014;63(2):63-65

9.The Role of Protease Activated Receptors and Proteases in Subtly Inflamed Diarrhea-Predominant Irritable Bowel Syndrome.

Yunju JO

The Korean Journal of Gastroenterology 2014;63(1):59-61

10.New Consensus on the Management of Barrett's Dysplasia and Early Stage Esophageal Adenocarcinoma: Limited Evidence, but Best Available Guidance (Gastroenterology 2012;143:336-346).

Yunju JO

Journal of Neurogastroenterology and Motility 2012;18(4):455-456

1.Chronic Gastric Volvulus by Diaphragmatic Hernia and Gastroparesis.

2.Gastric Emptying in Patients With Functional Dyspepsia and Patients With Migrain: Author's Reply.

3.Noncardiac Chest Pain in Young Patients.

4.Erratum: Gastric Emptying in Migraine: A Comparison With Functional Dyspepsia.

5.Marked Deposition of Eosinophil-Derived Neurotoxin in Adult Patients With Eosinophilic Esophagitis (Am J Gastroenterol 2010;105:298-307).

6.Eosinophilic Esophagitis: Update 2012.

7.Effect of Amitriptyline in Patients with Functional Dyspepsia.

8.Decreased Eradication Rates of Helicobacter pylori and Problem Solving.

9.The Role of Protease Activated Receptors and Proteases in Subtly Inflamed Diarrhea-Predominant Irritable Bowel Syndrome.

10.New Consensus on the Management of Barrett's Dysplasia and Early Stage Esophageal Adenocarcinoma: Limited Evidence, but Best Available Guidance (Gastroenterology 2012;143:336-346).

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