1.Diagnosis of vertebrobasilar arterial insufficiency by transcranial color duplex sonography
Lin HE ; Yunhua GAO ; Song ZUO ; Hongmei XIA ;
Journal of Third Military Medical University 2003;0(08):-
Objective To evaluate the diagnostic value of transcranial color duplex sonography for vertebrobasilar arterial insufficiency (VBI). Methods Transcranial color duplex sonography was performed on 30 healthy controls and 30 VBI patients confirmed clinically to examine the flow velocities and wave form parameters of the main supra and infra tentorial basal cerebral arteries. The anterior, middle, and posterior cerebral arteries on either side of the cranium and the vertebrobasilar system were observed using a 2.0 MHz transducer of a computed sonographic system. Results The vertebral artery system resistance index and pulsitive index were significantly higher in VBI patients than those in the controls ( P
2.Relationship between blood ox-LDL levels in coronary sinus and impaired endothelium-dependent vasodilation in patients with coronary artery disease
Hongmei DONG ; Lan HUANG ; Yaoming SONG ; Aimin LI ; Xuejun YU ; Zhaohua GENG ; Jun JIN ; Jun QIN ; Gang ZHAO ; Xiaobo ZHOU ; Yunhua GAO ; Hongmei XIA
Journal of Third Military Medical University 2003;0(18):-
Objective To investigate the relationship between the oxidized low-density lipoprotein(ox-LDL) in the blood from the coronary sinus and impaired endothelium-dependent vasodilation in patients with coronary artery disease(CHD).Methods Four groups of patients were subjected,including acute myocardial infarction group(AMI,n=22),unstable angina group(UA,n=29),and stable angina group(SA, n=25) and control group(n=20) who was first suspected as CHD and then verified with normal coronary angiograms.Blood form the coronary sinus was collected through cardiac cathetering and the ox-LDL level was measured by Sandwich ELISA method.Brachial arterial hyperemia-induced flow mediated dilation(FMD) and sublingual nitroglycerin(NTG) mediated vasodilation were measured by high resolution ultrasound.Results The blood level of ox-LDL in patients with CHD was markedly higher than those in control group(P
3.Epidemiologic investigation of chronic kidney disease in adult urban population of Hezhou Guangxi
Yunhua LIAO ; Ling PAN ; Qingyun CHEN ; Li HUANG ; Dongmei HUO ; Yashan SONG ; Ying CHEN ; Xiping TANG ; Jianhao MA ; Yuhuan PENG ; Qiongwen CHEN ; Feiqun SU ; Cuiping ZHOU ; Shuilian LI
Chinese Journal of Nephrology 2008;24(10):701-705
Objective To investigate the prevalence and risk factors of chronic kidney disease (CKD) in the adult urban population of Hezhou Guangxi. Methods One thousand and two hundred urban residents (older than 18 years) from Hezhou Guangxi were randomly selected using a random sampling. All the residents were interviewed. Their morning spot urine were tested to determine albumin to ereatinine ratio (abnormal:≥30 mg/g), and renal function [abnomal: eMDRD <60 ml·min-1·(1.73 m2)-1] was assessed. Morning spot urine dipstick of hematuria (abnormal:≥1 +) was confirmed by microscopy (abnormal: 3 red blood cells/HP). The associations among demographic characteristics, health eharacteristies and indicators of kidney damage were examined. Results Eligible data of 1069 subjects were enrolled in the study. The prevalence of albuminuria was 7.5%, hematuria 4.8%, and reduced eGFR 3.6%. The prevalence of kidney disease was 14.4% and the recognition was 1.4%. Age (OR 1.022, 95%CI 1.008-1.035), gender (OR 2.249, 95%CI 1.502-3.367), diabetes mellitus (OR 7.422, 95%CI 3.985-13.825) and hypertension (OR 4.397, 95% CI 2.601-7.432) were independently associated with CKD. Conclusions The prevalence of chronic kidney disease is 14.4% and the recognition is 1.4% in adult urban population of Hezhou Guangxi. Independent risk factors associated with chronic kidney disease are age, gender, diabetes mellitus and hypertension which is similar to those in developed countries and domestic big cities.
4.Determination of aromadendrin in Euonymus alatus by HPLC.
Yunhua CHEN ; Muxin GONG ; Chao ZHANG ; Yafang SONG ; Ping YU
China Journal of Chinese Materia Medica 2010;35(19):2565-2567
OBJECTIVETo establish a HPLC method to determine the content of aromadendrin in Euonymus alatus.
METHODKromasil 100-5C18 column was used with a mobile phase composed of acetonitrile-0.3% glacial acetic acid (24:76) at a flow rate of 1.0 mL x min(-1). The detection wavelength was 292 nm and the temperature of column was 30 degrees C.
RESULTThe calibration curve was linear in the range of 0.051-2.04 microg for aromadendrin. The correlation coefficient of the calibration curve was 0.999 9. Twenty batches of the crude E. alatus purchased from different areas were determined and the contents of aromadendrin in the twigs of E. alatus were fluctuated from 0.001 57% to 0.041 6%.
CONCLUSIONThis method is simple, repeatable and can be used for determination of aromadendrin.
Chromatography, High Pressure Liquid ; methods ; Drugs, Chinese Herbal ; chemistry ; Euonymus ; chemistry ; Flavonoids ; isolation & purification ; Plant Extracts ; chemistry ; Plant Stems ; chemistry
5. Evaluation of the right ventricular function in patients with pneumoconiosis by echocardiography
Wei WANG ; Wenli CHEN ; Cuiqiao JIA ; Xiaoliang WU ; Hongjuan SHEN ; Si CHEN ; Xiaodan SONG ; Yunhua LU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2018;36(3):224-226
Objective:
To investigate right ventricular function in patients with pneumoconiosis, and to provide a basis for quantitative diagnosis and treatment of pneumoconiosis in clinical practice.
Methods:
A total of 43 patients with pneumoconiosis who were hospitalized consecutively in Shijiazhuang Prevention and Treatment Center for Occupational Diseases from May 2015 to May 2016 were enrolled, and according to the stage of pneumoconiosis, they were divided into stage I group with 16 patients, stage II group with 14 patients, and stage III group with 13 patients. A total of 16 healthy subjects were enrolled as control group. Echocardiography was performed and the relevant parameters were recorded, i.e., right ventricular transverse diameter (RVTD), tricuspid annular plane systolic excursion (TAPSE), and right ventricular myocardial performance index(Tei index).
Results:
There were significant differences in Tei index and TAPSE between all groups (
6.Video assisted application in minimally invasive cardiac surgery
Chunsheng LI ; Zhong LU ; Zhongya YAN ; Yu YAN ; Yunhua SHEN ; Ru ZHANG ; Xiaorong SONG ; Cheng WANG
Chinese Journal of Postgraduates of Medicine 2019;42(5):457-460
Objective To investigate the short-term efficacy and safety through analyzing the results of 11 cases of video assisted minimally invasive cardiac surgery. Methods Eleven patients who had underwent video assisted minimally invasive cardiac surgery in the second hospital of Anhui medical university from November 2017 to August 2018 were retrospectively analyzed. One patient underwent simple atrial septal defect repair, 6 patients underwent atrial septal defect repair+tricuspid valve repair, 3 patients underwent mitral valve replacement, and 1 patient underwent mitral valve repair + tricuspid valve repair. Results All patients underwent video cardiac surgery without death, with no major bleeding (need secondary thoracotomy to stop bleeding) and no neurological complications. One patient of incision fat liquefaction healed after dressing change. One patient developed lower limb artery stenosis, which was treated conservatively and discharged after hospitalization. Conclusions Video assisted minimally invasive cardiac surgery can be safely applied to simple congenital heart disease and valve surgery as long as patients are strictly screened. Due to the advantages of small trauma, less bleeding, and quick recovery, it is worth promoting.
7.Research progress of intestinal dysbacteriosis in colorectal cancer and metastasis
Feng LI ; Jinzhou ZHENG ; Jianfeng YANG ; Yunhua QIU ; Xiaoyun SONG ; Xiqiu ZHOU
Chinese Journal of Primary Medicine and Pharmacy 2019;25(6):759-761
Colorectal cancer is one of the most common gastrointestinal malignancies with high incidence rate and mortality rate. Human intestinal microbiota play crucial roles in multiple aspects including immune function, digestion and metabolism.Current research literature suggests that there is a significant connection between intestinal dysbacteriosis and colorectal cancer.However,it is not clear how intestinal dysbacteriosis is involved in the initiation, progress and metastasis of colorectal cancer.In this paper,the influence discussed from three aspects.
8.Exploration of undergraduate practice teaching method for nursing internal medicine based on BOPPPS teaching model
Na LI ; Ruolin HAN ; Yunhua SONG ; Ying TIAN ; Xiumei ZHANG ; Weijian CHEN ; Hongmin LIANG
Chinese Journal of Medical Education Research 2023;22(4):636-640
Objective:To explore the feasibility of applying BOPPPS (B-bridge in, O-objective, P-pre-assessment, P-participatory learning, P-post-assessment, S-summary) course design mode in the teaching of internal medicine practice for nursing undergraduates.Methods:A total of 73 nursing interns of Kunming Medical University were selected as subjects and divided into the experimental group ( n=30) and the control group ( n=43). The experimental group adopted the practice teaching method based on BOPPPS model, while the control group adopted the traditional teaching method. Students' evaluation was collected by questionnaire. The students' comprehensive reasoning ability, holistic nursing skills ability and clinical nursing evaluation ability were evaluated by taking out questions from the question bank. And the results of teachers' evaluation on the participation of case study and problem solving in the process of students' internship were collected. SPSS 20.0 was used for t-test. Results:The students' evaluation of the practice process in the experimental group (86.81±2.85) was significantly better than that in the control group (82.61±3.82) ( P<0.001). The experimental group was significantly better than the control group in comprehensive reasoning of clinical thinking and assessment of holistic nursing ability ( P <0.001). Teachers' evaluation in the experimental group was better than that in the control group ( P <0.05). The overall effect of the experimental group (20.60±1.73) was significantly better than that of the control group (17.84±1.70) ( P <0.001). Conclusion:BOPPPS mode is helpful for teachers to carry out and demonstrate holistic nursing teaching with symptoms as the core according to the overall teaching objectives of nursing internal medicine, optimize the time arrangement and knowledge structure, improve the practice efficiency, and promote the establishment of holistic nursing thinking mode of students.
9.The application of individual open fenestrated stent graft in type A aortic dissection
Chunsheng LI ; Zhongya YAN ; Zhong LU ; Yunhua SHEN ; Yu YAN ; Ru ZHANG ; Xiaorong SONG
The Journal of Practical Medicine 2018;34(3):393-396
Objective To observe the recent clinical effect of application of individual open fenestrated stent graft in type A aortic dissection without developing the greater curve of the arch. Method From December 2014 to November 2016,15 patients of type A aortic dissection without developing the greater curve of the arch un-derwent endovascular total arch replacement using individual open fenestrated stent graft in the Anhui Province Hospital.Among them,8 cases were only operated with open fenestrated stent graft in aortic arch, 7 cases with open fenestrated stent graft in aortic arch added 1 or 2 small stent graft.Result There was 1 postoperative death caused by severe low cardiac output. The rest of the patients were successfully discharged from the hospital, without ner-vous system and related complications. Follow-up computerized tomographic angiography showed all implanted stents were wide expansion and in a good position. No endoleaks and thrombus obliterated of the corresponding false lumen was found. Conclusion Individual open fenestrated stent graft is suitable for type A aortic dissection without developed the greater curve of the arch.Its significantly simplify the total arch replacement operation steps, reduce anastomotic and shorten the lower body arrest time. Consequently, reduce the risk of operation difficulty, postoperative blood loss and other viscera damage probability significantly. The early and middle term clinical re-sults is satisfactory.
10. Comparison between metabolic syndrome and framingham risk score as predictor of cardiovascular disease among Kazakhs population
Shuxia GUO ; Wenwen YANG ; Rulin MA ; Xianghui ZHANG ; Heng GUO ; Jia HE ; Lei MAO ; Lati MU ; Kui WANG ; Yunhua HU ; Yizhong YAN ; Jingyu ZHANG ; Jiaolong MA ; Jiaming LIU ; Xinping WANG ; Yanpeng SONG
Chinese Journal of Endocrinology and Metabolism 2019;35(12):1037-1042
Objective:
To compare metabolic syndrome(MS)with Framingham risk score as predictors of cardiovascular disease(CVD)among Kazakhs population.
Methods:
The participants were the residents who had been followed up for more than 5 years in representative areas of Kazakhs in Xinjiang. We assigned MS a continuous risk score for predicting the development of CVD based on the weights of MS components. MS and Framingham risk score were compared in terms of their ability in predicting years in representative areas of Kazakhs in Xinjiang. We assigned MS a continuous risk score for predicting the development of CVD based on the weights of MS components. MS and Framingham risk score were compared in terms of their ability in predicting development of CVD using Cox regression and receiver operating characteristic curve.
Results:
The incidence of CVD was 13.87%. The incidence of CVD was higher in the MS group than it in the non-MS group(21.59%