1.Studies on the Change of Pulmonary Artery Pressure in Early Neonatal Period.
Jung Ae KIM ; Yung Kyun OH ; Byung Kiu PARK ; Hee Shang YOUN ; Myung Kul YUM
Journal of the Korean Pediatric Society 1990;33(8):1081-1086
No abstract available.
Pulmonary Artery*
2.Modified Microsurgical and Standard Lumbar Discectomy ; Comparative Study.
Ho Kyun HA ; Suck Jun OH ; Hae Dong JHO ; Yung Rak YOO ; Nam Kyu KIM ; Hwan Yung CHUNG
Journal of Korean Neurosurgical Society 1983;12(4):583-588
To obtain wider versatility and greater reach in microsurgical lumbar discectomy, modified procedure has been performed on 263 patients in 1979-1983. It consisted of a smaller midline incision, removal of lateral half of the spinous process, partial but sufficient microdrilling of the lamina, use of a modified slender Taylor retractor, flavotomy, preservation of epidural adipose-areolar tissue etc. Particularly a slender Taylor-Chung retractor offered yielding surgical opening and therefore secured free of pituitary forceps to every direction. The microsurgical results including 72 bisegmental and 8 trisegmental discectomies were compared with those of standard operations of same number performed by same surgeon in 1972-1979, for the good contrast. Mean blood loss per operation was 94 ml with the standard discectomy and 46 ml with microsurgery. Dural tear occured in 17 cases undergoing standard operation and in 3 undergoing microsugery. The mean time until return to duty was 8.6 weeks with standard, compared with 4.2 weeks. In the microsurgical group, 3 patients had postoperative discitis while 2 had in the standard. In this series, the results of microsurgery surpasses the standard in the convalescent phase. Major advantages of this modified microsurgical technique were its ability to secure the greater reach to remove disc material as much as possible and to preserve the integrity of normal tissue better.
Discitis
;
Diskectomy*
;
Humans
;
Microsurgery
;
Surgical Instruments
3.Extirpated Intra- and Extracranial Metastasis of Hepatocellular Carcinoma: Case Report.
Ho Kyun HA ; Suck Jun OH ; Hae Dong JHO ; Young Rak YOO ; Nam Kyu KIM ; Hwan Yung CHUNG
Journal of Korean Neurosurgical Society 1984;13(3):491-495
A rare case of surgically extirpated intra- and extracranial metastasis of hepatocellular carcinoma is reported. This dumb-bell shaped tumor simulated malignant meningioma on computerized tomography brain scan and cerebral angiography. Removal of the mass was successfully achieved by external carotid ligation and CUSA dissection. We suggest that, when investigating patient with suspected cranial secondaries particulary if there is a bony involvement, serum alpha-fetoprotein and hepatic ultrasound should be carried out as screening procedures.
alpha-Fetoproteins
;
Brain
;
Carcinoma, Hepatocellular*
;
Cerebral Angiography
;
Humans
;
Ligation
;
Mass Screening
;
Meningioma
;
Neoplasm Metastasis*
;
Ultrasonography
4.A CLINICAL STUDY ON ORAL & MAXILLOFACIAL PATIENTS VISITING CHONNAM UNIV-HOSPITIAL EMERGENCY ROOM
Kyu Seung CHO ; Ki Yung KIM ; Sung Hun LEE ; Hong Ju PARK ; Kwang Sub SO ; Yong Ki CHO ; Hee Kyun OH ; Sun Youl RYU
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1997;19(4):435-446
5."Recovery Only" ST-Segment Depressions in an Exercise Treadmill Test and the Prediction of Coronary Artery Disease.
Namho LEE ; Seung Hyuk CHOI ; Woo Jung PARK ; Koo Yung CHO ; Yung Jin CHOI ; Dae Kyun PARK ; Kyung Soon HONG ; Young Cheoul DOO ; Kyoo Rok HAN ; Dong Jin OH ; Kyu Hyung RYU ; Chong Yun RHIM ; Kwang Hahk LEE ; Yung LEE
Korean Circulation Journal 2002;32(2):131-136
BACKGROUND AND OBJECTIVES: "Recovery only" ST-segment depressions are sometimes detected during an exercise treadmill test. We undertook this study in order to clarify the predictive value of exercise-induced ST-segment depression occurring in recovery only. SUBJECTS AND METHODS: The study included 931 patients who had both a sign or symptom -limited treadmill test. Of the 66 patients who demonstrated abnormal ST-segment responses, 43 experienced ST-segment depressions during exercise (Group A) and 23 displayed such responses only during recovery (Group B). RESULTS: The positive predictive value of an exercise treadmill test for significant angiographic disease in group A (81.3%) was statistically different from the predictive value in group B (30.4%). Horizontal ST-segment depression in recovery periods and female sex were statistically significant factors favoring negative coronary angiographic results. CONCLUSION: The occurrence of horizontal mild ST-segment depression during only the recovery periodgenerally represents a "false positive" response, particularly in female patients.
Coronary Artery Disease*
;
Coronary Disease
;
Coronary Vessels*
;
Depression*
;
Exercise Test*
;
Female
;
Humans
6.The Optimal Timing to Measure C-Reactive Protein to Predict Cardiac Events in Patients with Unstable Angina.
Young Cheoul DOO ; Woo Jung PARK ; Sung Hoon PARK ; Kyung Ho KIM ; Ji Yong CHOI ; Koo Yung CHO ; Yung Jin CHOI ; Dae Kyun PARK ; Kyung Soon HONG ; Kyoo Rok HAN ; Nam Ho LEE ; Dong Jin OH ; Kyu Hung RYU ; Chong Yun RIM ; Kwang Hahk LEE ; Yung LEE
Korean Circulation Journal 2001;31(3):290-296
BACKGROUNDS AND OBJECTIVES: C-Reactive protein (CRP) levels are powerful predictors of cardiac complications and death in patients with unstable angina unrelated with myocardial cell damage or myocardial ischemia. This study was performed to determine the optimal timing to measure CRP to predict cardiac events in patients with unstable angina. MATERIALS AND METHOD: The study was comprised 50 patients with unstable angina (Braunwald Class IIIb). We randomized the study subjects by the time of CRP elevation (> 8mg/L): Group A (on admission, 15 patients), Group B (during hospitalization, 19 patients), and Group C (at discharge, 19 patients). RESULTS: 1) CRP levels (median and range) of Group A, B, and C were 10.6 (8.2-24.2), 12.8 (8.1-33.7), and 10.3 (8.1-18.7) mg/L, respectively (p=S). 2) During clinical follow-up at a mean duration of 12 months, there were 1 death, 1 myocardial infarction, 6 revascularization therapy (PTCA or CABG) and 11 recurrent angina. 3) In Group A, 10 cardiac events (1 myocardial infarction, 4 revascularization therapy, and 5 recurrent angina) occurred. The elevated levels of CRP predicted cardiac events during clinical follow-up with sensitivity of 53%(10/19), positive predictive value of 67%(10/15), and negative predictive value of 74%(26/35). In Group C, 13 cardiac events were occurred. Sensitivity, positive and negative predictive value to predict cardiac events of elevated levels of CRP were 68%(13/19), 68%(13/19) and 81%(25/31), respectively. 4) Elevated levels of CRP (>8mg/L) were predictors for cardiac events in patients with unstable angina (Group A; p<0.05, Group B; p<0.05, Group C; p<0.001). However, by logistic regression analysis, CRP values > 8mg/L at discharge were only predictive of cardiac events with odd ratio of 6.01 (95% CI 1.50-44.3, p<0.05). CONCLUSIONS: CRP (> 8mg/L) was elevated in 38% of patients at discharge and elevated levels of CRP at discharge were only predictive of cardiac events in patients with unstable angina.
Angina, Unstable*
;
C-Reactive Protein*
;
Follow-Up Studies
;
Hospitalization
;
Humans
;
Logistic Models
;
Myocardial Infarction
;
Myocardial Ischemia
7.Retroperitoneal Hematoma Caused by Ruptured Pancreaticoduodenal Artery Aneurysm.
Yung Suk KIM ; In Kyu LEE ; Yoon Suk LEE ; Hae Myung JEUN ; Suk Kyun CHANG ; Soon Nam OH ; Sang Hun LEE
Journal of the Korean Surgical Society 2005;68(3):244-246
A ruptured aneurysm of the pancreaticoduodenal arteries is an emergency condition, with a high mortality rate. Therefore, early diagnosis and adequate management are needed. Recently, treatment with a transcatheter arterial embolization has decreased the mortality rate. A 68-year-old man presented with persistent abdominal pain and dyspnea. Contrast abdominal computed tomography revealed a large retroperitoneal hematoma, with an actively bleeding focus. An urgent celiac and superior pancreaticoduodenal arteriogram showed a contrast extravasation, about 15 X 8 mm in size, with a saccular aneurysm of the distal anterior superior pancreaticoduodenal artery; therefore transcatheter arterial embolization was performed. The patient's condition improved without complication after the embolization.
Abdominal Pain
;
Aged
;
Aneurysm*
;
Aneurysm, Ruptured
;
Arteries*
;
Dyspnea
;
Early Diagnosis
;
Emergencies
;
Hematoma*
;
Hemorrhage
;
Humans
;
Mortality
8.Comparison of an enzyme-linked immunosorbent assay with serum neutralization test for serodiagnosis of porcine epidemic diarrhea virus infection.
Jin Sik OH ; Dae Sub SONG ; Jeong Sun YANG ; Ju Young SONG ; Hyoung Joon MOON ; Tae Yung KIM ; Bong Kyun PARK
Journal of Veterinary Science 2005;6(4):349-352
An indirect porcine epidemic diarrhea (PED) virus (PEDV) enzyme-linked immunosorbent assay (ELISA) was compared with the serum neutralization (SN) test by testing 46 samples from experimentally infected sows, 73 samples from naive sows, and 1, 024 field sow samples from 48 commercial swine farms of undefined PED status. The SN test and the ELISA were performed using PEDV, KPEDV-9 strain. Viral proteins as a coating antigen of PEDV ELISA were extracted from the cytoplasm of PEDV-infected Vero cells using a non-ionic detergent, Triton X-100, and a simple protocol of PEDV ELISA was followed. The presence of antibodies in these experimental samples was confirmed by SN and ELISA in which the sensitivity of the ELISA was 89.1%, and the corresponding specificity was 94.5%. On testing 1, 024 field samples, an overall agreement of 84.2% was generated between the SN and ELISA. This study demonstrates that the PEDV ELISA is a useful serodiagnostic screening test at herd level for detecting swine antibodies against PEDV.
Animals
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Antibodies, Viral/blood
;
Coronavirus Infections/diagnosis/*veterinary/virology
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Diarrhea/diagnosis/*veterinary
;
Enzyme-Linked Immunosorbent Assay/veterinary
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Female
;
Neutralization Tests/veterinary
;
Sensitivity and Specificity
;
Swine
;
Swine Diseases/diagnosis/*virology
9.The Clinical Study on Marfan Syndrome.
Jung Sim KIM ; Dong Kyu JIN ; See Hwan KO ; Jee Yeon MIN ; I Seok KANG ; Kye Won JEON ; Yung Lan CHOI ; Heung Jae LEE ; Seung Woo PARK ; Won Ro LEE ; Chong Suh LEE ; Sei Yeul OH ; Chang Won KI ; Han Wook YOO ; In Sook PARK ; Jae Kon KO
Journal of the Korean Pediatric Society 1998;41(10):1411-1416
PURPOSE: The aim of this study was to assess the involvement of several organs patients with Marfan syndrome in Korea. Also the clinical features in childhood patients with Marfan syndrome were assessed. METHODS: Thirty-eight cases of Marfan syndrome were enrolled in this study. Clinical evaluations of the musculoskeletal, cardiovascular and occular system were performed in all cases. RESULTS: The musculoskeletal system was involved in 32 cases (84.2%) and occular system in 24 cases (63.1%). Cardiovascular abnormalities were found in 19 cases (50.0%) at initial evaluation. Family history was involved in 21 cases (55.2%). Ectopia lentis was found in 17 cases (70.8%). Severe myopia and iris abnormalities were also present in 14 cases (58.2%). The ascending aorta was dilated in 13 cases (34.2%). Emergency operation was performed in 3 cases (7.9%) because of a dissecting aorta. Mitral regurgitation and prolapse were found in 29 cases (76.4%) and other valve insufficiency was accompainied in 5 cases (13.1%). Of the 38 cases, 29 patients (79.3%) were less than 15 years of age and their major manifestations were occular problems in 23 cases (79.3%), and family history in 17 cases (58.6%). In one infant, severe heart failure was the predominant clinical feature. CONCLUSION: The clinical features of Korean patients with Marfan syndrome were summarized in this report. Heart failure was the main manifestaton in infantile Marfan syndrome. Early treatment with beta-blocker and valvular replacement can prevent fatality, i.e. aortic dissection, in this disease, concern and management should be advocated in the early detection of Marfan syndrome.
Aorta
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Cardiovascular Abnormalities
;
Ectopia Lentis
;
Emergencies
;
Heart Failure
;
Humans
;
Infant
;
Iris
;
Korea
;
Marfan Syndrome*
;
Mitral Valve Insufficiency
;
Musculoskeletal System
;
Myopia
;
Prolapse
10.Affecting Factors on Endothelial Dysfunction in Diabetic End Stage Renal Disease Patients on Hemodialysis.
Dong Ryeol RYU ; Hoon Young CHOI ; Shin Wook KANG ; Kyu Hun CHOI ; Ho Yung LEE ; Dae Suk HAN ; Ea Wha KANG ; Young Ah KIM ; Sung Jin OH ; Beom Seok KIM ; Sug Kyun SHIN
Korean Journal of Nephrology 2005;24(1):47-56
BACKGROUND: Non-traditional risk factors of cardiovascular disease such as endothelial dysfunction, inflammation and malnutrition may be significant contributors to the excessive cardiovascular mortality in end stage renal disease (ESRD) patients. This study was undertaken to evaluate endothelial function in diabetic ESRD patients on hemodialysis and correlation between endothelial dysfunction and clinical, biochemical parameters. METHODS: Twenty eight stable diabetic ESRD patients (M: F=1.3: 1, average age: 60.1+/-1.0 yr) on hemodialysis were included. flow-mediated dilation (FMD) of brachial artery was measured using Doppler ultrasonography with 10 MHz transducer. Subjective global assessment (SGA) was used to assess the nutritional status of patients. RESULTS: The FMD (%) (% change of brachial artery diameter between before and after cuff inflation) was 5.1+/-1.0%. Serum albumin and C-reactive protein (CRP) were independent factors influencing SGA. When the patients were divided into groups according to history of ischemic heart disease (IHD), systolic pressure was significantly higher and FMD (%) was significantly lower in the group of patients with IHD compared with the group of patients without IHD. The FMD (%) showed significant positive correlation with SGA, serum albumin, and significant negative correlation with CRP. On multiple regression analysis, however, only CRP was an independent factor affecting FMD (%). CONCLUSION: These findings suggest that CRP influenced the nutritional status of diabetic ESRD patients on hemodialysis, and endothelial dysfunction, estimated by FMD, was significantly correlated with CRP. Therefore, CRP can be a modifiable risk factor for endothelial dysfunction in diabetic ESRD patients on hemodialysis.
Blood Pressure
;
Brachial Artery
;
C-Reactive Protein
;
Cardiovascular Diseases
;
Humans
;
Inflammation
;
Kidney Failure, Chronic*
;
Malnutrition
;
Mortality
;
Myocardial Ischemia
;
Nutritional Status
;
Renal Dialysis*
;
Risk Factors
;
Serum Albumin
;
Transducers
;
Ultrasonography, Doppler