Malignant fibrous histiocytoma is a predominant pleomorphic sarcoma usually occurring in the deep soft tissue of adults. The tumor commonly occurs in the extremities or in the retroperitoneum. We report a case of malignant fibrous histiocytoma of the paratesticular tissue. A 59 year old man presented with a 7 month history of a painless right upper scrotal mass. Radical orchiectomy with high ligation of the spermatic cord and wide excision of surrounding tissue was performed and then he was received external beam radiation to the right inguinal area and scrotum. He was well 15 months later with no evidence of local recurrence or metastases at follow up study.
Adult ; Extremities ; Follow-Up Studies ; Histiocytoma, Malignant Fibrous* ; Humans ; Ligation ; Middle Aged ; Neoplasm Metastasis ; Orchiectomy ; Recurrence ; Sarcoma ; Scrotum ; Spermatic Cord

A previously healthy 22-year-old woman was admitted with a complaint of right upper quadrant abdominal pain for 2 weeks. Her past history was not remarkable. On admission, HBsAg and anti-HCV were negative and alpha-FP was within normal range. Abdominal sonography and CT showed a mass in liver measuring 10 11 cm with features of central necrosis and hemorrhage. On 6th hospital day, hemoperitoneum developed suddenly. She underwent emergency laparotomy and trisegmentectomy. Intraoperative finding revealed a hemoperitoneum with a tumor filled with liquefied necrotic tissues. Microscopically, the tumor was mostly composed of pleomorphic spindle cells with abundant anastomosing vascular channels and partly composed of tumor cells with trabecular arrangement. On immunohistochemical staining, tumor cells reacted with cytokeratin and vimentin, while CD34 and hepatocyte staining revealed negative. She died 2 months after the operation. We report a case of rapidly deteriorated primary sarcomatoid hepatocellular carcinoma in a young female without any risk factor.
Adult ; Carcinoma, Hepatocellular/diagnosis/*pathology ; Female ; Humans ; Liver Neoplasms/diagnosis/*pathology ; Sarcoma/diagnosis/*pathology