1.A Case Report of Total Penile Skin Graft.
Young Joo KIM ; Yung Hoon PARK ; Uoon Hyung LEE
Korean Journal of Urology 1970;11(2):71-74
A case of complete loss of penile skin treated with scrotal skin graft was presented in a 26 year old male. This case was noted to be a complete loss of penile skin which was developed under local anesthesia with formalin 30 cc during circumcision. The implantation of the penis in the scrotum was performed by the scrotal tunnel method. Complete logs of penile skin was restored by implanting the denuded surface under the subcutaneous tissue of the scrotum.
Adult
;
Anesthesia, Local
;
Circumcision, Male
;
Female
;
Formaldehyde
;
Humans
;
Male
;
Penis
;
Scrotum
;
Skin*
;
Subcutaneous Tissue
;
Transplants*
2.Measurement and Comparison of Hydration and Lipid Levels between Patients with Acne vulgaris and Patients with Atopic Dermatitis.
Seung Hun LEE ; Tae Hyun PARK ; Yung Jae LEE ; Sang Hoon PARK
Korean Journal of Dermatology 1995;33(3):459-466
BACKGROUND: Skin surtice lipids increase and decrease in tints with acne vulgaris and in patients with atopic dermatis, respectively. Notably, hydratior. in decreased in patients with atopic dermatitis. Clinically it is common for the two diseases to occur together. OBJECTIVE: We would like to find out the rate, clinical cteristics, and hydration and lipid levels when acne vulgaris and atopic dermatitis concur. METHODS: We classific the clinical levels and measured the hydration and lipid levels of the face and forearm area of patients with acne vulgaris, patients phatopic dermatitis, and patients with both diseases, who visited the Youngdong Severance Hospital. RESULTS: 1) 13.8% (14/102) of patients with acne vulgaris had at, epidermatitis. 31.1% (14/45) of patients with atopic dermatitis had acne vulgaris. 2) Patients with acne vulgaris had increased lipid levels and normal hydration levels. 3) Patients with atopie dermatitis had decreased lipid and iylration levels. 4) Patients withoth cnevulgaris and atopic dermatitis a no severe grade of acne vulgaris, and showed decreased hydration but normal lipid levels. CONCLUSION: In patients with both arne vulgaris and atoic dermatitis, clinically acne vulgaris was not severe and hydation levels were lower than normal controls.
Acne Vulgaris*
;
Dermatitis
;
Dermatitis, Atopic*
;
Forearm
;
Humans
;
Skin
3.Field survey on the freshwater snails in Cheju Province(Quelpart lsland), Korea: Especially on presence or not of Parafossarulus manchouricus.
Suck Young KANG ; In Kyu LOH ; Yung Hoon PARK ; Byung Chan KIM ; Too Bong LIM
The Korean Journal of Parasitology 1964;2(3):183-188
The question of infectivity and prevalence of Clonorchis sinensis in Cheju province (Quelpart Island) was arisen to authors since the several surveys on the endemic diseases were performed in this island. Therefore, authors decided to solute this question. Then the survey on the possible second intermediate host of Clonorchis sinensis was performed and reported already with negative finding. At present time, authors carried out the collection of all kinds of fresh-water snails through all areas of this island, to confirm the presence or not of Parafossarulus manchouricus, the only first intermediate host of Clonorchis sinensis in Korea . And the following results were obtained. The fresh-water snails collected in the survey were Semisulcospira libertina Gould and Lymnaea ollula Gould. Parafossarulus manchouricus Bourguigant was not collected in this island. It is confirmed that the Clonorchis sinensis can not be prevalent in this island.
parasitology-helminth-trematoda-Clonorchis sinensis
;
life cycle
;
epidemology
;
Parafossarulus manchouricus
;
Semisulcospira libertina Gould
;
Lymnaea ollula Gould
4.Effects of Ischemic Preconditioning on Hypoxia-Reoxygenation Injury of Cardiac Myocyte in Culture.
Hoon Ki SUNG ; Jeong Hyun PARK ; Yung Chang LEE
Korean Journal of Anatomy 2000;33(4):433-446
Short period of ischemia and reperfusion protect heart against subsequent prolonged ischemia-reperfusion injury. This phenomenon was first described by Murry et al in 1986, who demonstrated that four 5-minute coronary artery occlusions followed by equal period of reflow at each time before a subsequent prolonged occlusion resulted in a reduction of infarct size in dog. Although the precise mechanism of preconditioning remains unknown, this phenome-non is present among different species of mammals, including dogs, rats, pigs, rabbits, and human. The objects of present study was to investigate effect of ischemic preconditioning on cell viability, structural changes and apoptosis during 60 min hypoxia and 60 min reoxygenation of the cell. In present study we investigated through cell culture system using myocyte of three days old neonatal rat cultured for three days. During hypoxia and reoxygenation, differences between preconditioned and nonpreconditioned of beating counts, morphological and structural changes are investigated through inverted phase contrast microscope and transmis-sion electron microscope. To detection of apoptotic cell, TUNEL (TdT-mediated dUTP-biotin nick end labeling) stain was accomplished, and through which we invesigate the effects of preconditioning on apoptosis. Viabiliy of each cell and it's mitochondria were measured quantitatively by MTT assay. After 60 min of hypoxia and 60 min of reoxygenation, beating rate decreased remarkably. But at the time of 60 min of reoxygenation, there was marked increase in beating count in pre-conditioned cell. Swollen mitochondria with amorphous granules in inner membrane, destroyed mitochondrial cristae, indented nuclear envelope, chromatin condensation, contracture of myofibril, fragmentation of myofilaments, cytoplasmic shrinkage were observed in both preconditioned cell and nonpreconditioned cell. But it is much less in pre-conditioned cell than in nonpreconditioned cell. MTT activity decreased in both experimental groups in compared with normal group, but in preconditioned group, MTT activity increased markedly in compared with nonpreconditioned group. And apoptosis is decreased by precontitioning in TUNEL staining. These results suggest that cardioprotective effects of ischemic preconditioning is mediated by attenuating structural destroy, increasing cell viability, decreasing apoptosis.
Animals
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Anoxia
;
Apoptosis
;
Cell Culture Techniques
;
Cell Survival
;
Chromatin
;
Contracture
;
Coronary Vessels
;
Cytoplasm
;
Dogs
;
Heart
;
Humans
;
In Situ Nick-End Labeling
;
Ischemia
;
Ischemic Preconditioning*
;
Mammals
;
Membranes
;
Mitochondria
;
Muscle Cells
;
Myocytes, Cardiac*
;
Myofibrils
;
Nuclear Envelope
;
Rabbits
;
Rats
;
Reperfusion
;
Reperfusion Injury
;
Swine
5.Clinical Application of Ambulatory Holter Electrocardiographic Monitoring.
Seog Won YANG ; Ja Cheon KIM ; Chung Kun PARK ; Chang Hoon LEE ; Young Bahk KOH ; Yung LEE
Korean Circulation Journal 1984;14(1):111-123
24-hour Holter ambulatory ECG monitoring has been examined for the cardiac evaluation during ordinary activities in 81 subjects with suspected or propostmyocardial infarction (PMI), 12-lead ECG and the 24-hour ECG tape showed similar basic rhythm, heart rates and conduction patterns, but ventricular premature contractions (VPCs) were more frequently recorded on the 24-hour tape. Of 17 PMI patients, one or more VPCs in 14 cases (82.4%), multifocal VPCs in 3 cases (17.6%) and bigeminy or paired VPCs in 5 cases (29.4%) and transient runs of ventricular tachycardia in 1 case (5.9%) were observed on the 24-hour monitoring. 2) Of 30 patients with typical or atypical chest pain, 20 examinees had changes in the ST segment and/or T wave, but 10 examinees did not have any pathological changes in the ST segment or in the T wave. 3) Of 26 patients with dizziness and palpitation during waking periods, sinus rates were 76.4+/-12.8/min. and the ranges were 134.1+/-15.1/min. and 58.7+/-9.1/min. Average sinus rates observed during sleeping periods were 61.6+/-10.3/min., the ranges were 92.7+/-11.4/min. and 51.5+/-8.7/min. In general, longer PR interval, QTc interval, QRS duration and high R amplitude were observed during sleeping periods than waking periods. 4) Of 64 patients without PMI, all subjects had episodes of normal sinus rhythm and brady-and-tachycardia syndrome in 5 cases, VPCs in 23 cases, APCs in 2 cases, AV block in 4 cases and W.P.W. syndrome in 2 cases were observed during 24-hour Holter ECG monitoring.
Atrioventricular Block
;
Chest Pain
;
Dizziness
;
Electrocardiography*
;
Heart Rate
;
Humans
;
Infarction
;
Tachycardia, Ventricular
6.Retroperitoneal cystic lymphangioma in an aged man: report of a case and review of the literature.
Seok Kil ZEON ; Seon Goo KIM ; Hee Jung LEE ; Yung Hoon WOO ; Soo Jhi SUH ; Kwan Kyu PARK
Journal of the Korean Radiological Society 1992;28(4):613-616
Retroperitoneal cystic lymphangioma is a rare benign tumor which had previously been difficult to diagnose preoperatively by conventional radiographic technique(1). Recent reports describe the computed tomographic and ultrasonographic findings in cystic lymphangioma(1,2). We report a case of retroperitoneal cystic lymphangioma, accurately diagnosed by lymphography, with computed tomographic findings and percutaneous drainage findings. To the best of out knowledge, this is the most aged case of retroperitoneal cystic lymphangioma of preoperatively diagnosed.
Drainage
;
Lymphangioma, Cystic*
;
Lymphography
7.Intravitary cardiac metastasis in primary hepatoma.
Kyu Hyung RYU ; Dai Young ZANG ; Shin Sung PARK ; Yung LEE ; Sang Hoon LEE ; Young Tak LEE ; Jin Suk SUH
Korean Circulation Journal 1993;23(1):123-128
Intracavitary metastasis is an uncommon secondary cardiac malignancy and metastasis to the right atrium and ventricle is even less common. Prior reports have demonstrated an association of this disease entity with sudden death. We report a recent experience of intracavitary cardiac metastasis of a primary hepatoma in a 24-year-old woman who presented with a exertional dyspnea and a syncopal episode.
Carcinoma, Hepatocellular*
;
Death, Sudden
;
Dyspnea
;
Female
;
Heart Atria
;
Humans
;
Neoplasm Metastasis*
;
Syncope
;
Young Adult
8.Relation Between Pulmonary Hypertension and Mitral Stenosis Severity in Patients Undergoing Balloon Mitral Commissurotomy.
Byung Jin KIM ; Yong Hyun PARK ; Yoong In PARK ; Jong Hoon LIM ; Hyun Myung OAH ; Joon Hoon JEONG ; Kook Jin CHUN ; Taek Jong HONG ; Yung Woo SHIN
Korean Circulation Journal 1997;27(5):523-531
BACKGROUND: In patients with mitral stenosis, the degree of pulmonary hypertension is expected to be related to the severity of mitral valve obstruction. However, some patients with severe mitral stenosis do not develop reactive pulmonary hypertension. MATERIALS AND METHODS: We evaluated 34 patients with symptomatic mitral stenosis undergoing percutaneous mitral valvuloplasty by clinical, echocardiographic, and invasive hemodynamic(cardiac cathrterization) data. Prevalvuloplasty data were available in 34 subjects[mean age 38+/-9 year ; women 74% ; NYHA class 1 (6 patients), class 2 (17 patients), class 3 (7 patients), class 4 (4 patients) ; in electrocardiography, NSR(23 patients), Atrial fibrillation(11 patients)]. RESULTS: 1) The pulmonary vascular bed gradient was significantly correlated with pulmonary vascular resistance(r=0.91), mean pulmonary artery pressure(r=0.82), transmitral mean pressure gradient(r=0.64) and mitral valve area(r=-0.48). The pulmonary vascular resistance was significantly correlated with mena pulmonary artery pressure(r=0.77), transmiral mean pressure gradient(r=0.61) and mitral valve area(r=-0.54), NYHA functional classification(r=0.36). However, the pulmonary vascular bed gradient and pulmonary vascular resistance was not significantly correlated with age, sex, cardiac output, the severity of mitral regurgitation and mean left atrial pressure. 2) The mean pulmonary artery pressure was significantly correlated with mean left atrial pressure(r=0.80), transmitral mean pressure gradient(r=0.72) and mitral valve area(r=-0.47). 3) When patients were divided into those with a pulmonary vascular bed gradient > 12mmHg and = 12mmHg, the two groups were significantly different for many of these measures-Pulmonary vascular resistance(p=0.004), mean pulmonary artery pressure(p=/p<0.0001), transmitral mean pressure gradient(p=0.008), mitral valve area(p=0.04). 4) The mean left atrial pressure was significantly correlated with mean pulmonary artery pressure but not with pulmonary vascular resistance and pulmonary vascular bed gradient as the index of reactive pulmonary hypertension. 5) Results of multiple regressin analysis of factors affecting pulmonary vascular bed gradient showed that transmitral mean pressure gradient was the most significant factor(op<0.0001). 6) The decrease in mean pulmonary artery pressure from immediate before to immediate after balloon commissurotomy was related to pulmonary vascular resistance(r=0.51), pulmonary vascular bed gradient(r=0.63), mean left atrial pressure(r=0.60), transmitral mean pressure gradient(r=0.50), mitral valve area(r--0.41). CONCLUSION: In patients with mitral stensis, the degree of reactive pulmonary hypertension was significantly related to the severity of mitral stenosis(transmitral mean pressure gradient, mitral valve area) but not to mean left artial pressure. In some patients the degree of mitral stenosis could not expect the development of reactive pulmonary hypertension. It is suggested that specific predictors of pulmonary hypertension on an individual patient cannot be identified based solely on the severity of mitral valve disease and must include many factors associated with pulmonary parenchymal diseases, other heart diseases, and duration of mitral stensis.
Atrial Pressure
;
Cardiac Output
;
Echocardiography
;
Electrocardiography
;
Female
;
Heart Diseases
;
Humans
;
Hypertension, Pulmonary*
;
Mitral Valve
;
Mitral Valve Insufficiency
;
Mitral Valve Stenosis*
;
Pulmonary Artery
;
Vascular Resistance
9.Evaluation of doppler echocardiographic patterns of left ventricular filling in the patients with recent acute myocardial infarction.
Sang Ho LEE ; Yung Hoon PARK ; Min Su SON ; Baek Sun HEUM ; Jai Woong CHOI ; Tae Hoon AHN ; Eak Kyun SHIN
Korean Circulation Journal 1993;23(2):223-229
BACKGROUND: Diastolic function can be assessed by Doppler-derived left ventricular(LV) filling patterns. E/A ratio<1 and prolongation of isovolumic relaxation time(IVRT) are diagnostic of impaired relaxation of left ventricle during diastole. In early stage of acute myocardial infarction, myocardial stiffness can normalize the E/A ratio and mask the Doppler indexes of abnormal relaxation in patients with acute myocardial infarction. METHODS: LV filling patterns were studied with Doppler echocardiography in 10 healthy subjects and 27 patients with recent acute myocardial infarction. Cardiac catherterization was performed in the 11+/-2 days after onset of acute myocardial infarction and left ventricular end-diastolic pressure(LVEDP) and myocardial stiffiness index(MSI) were studied. RESULTS: In patients with acute myocardial infarction, IVRT was significantly prolonged ; E/A ratio and deceleration time were decreased but not significantly different from those of normal subjects. In the patient's group of E/A>1,IVRT and atrial filling fraction(AFF) were significantly shortened, and LVEDP was significantly increased, compared to those of the patient's group of E/A<1. But ejection fraction was similar in both groups. In the patients with acute myocardial infarction, E/A ratio and LVEDP showed good correlation(r=0.64, p<0.05). MSI was increased in the patient's group of E/A>1 and also was well correlated with LVEDP(r=0.8, p<0.05). CONCLUSIONS: Thus we conclude that normal of increased E/A ratio in recent acute myocardial infarction may reflect increased LVEDP due to increased myocardial stiffness.
Deceleration
;
Diastole
;
Echocardiography*
;
Echocardiography, Doppler
;
Heart Ventricles
;
Humans
;
Masks
;
Myocardial Infarction*
;
Relaxation
10.The Occurrence of a Branchial Cleft Cyst in the Anterior Mediastinum: A Case Report.
Seong Hoon PARK ; Seong Hoon KIM ; Hyun Woong SHIN ; Hyun Chul JO ; Mi Yung SON ; Joon Hyuk GONG
Journal of the Korean Radiological Society 2008;59(2):107-110
Branchial cleft cysts and branchial anomalies develop from the branchial cleft apparatus that persists after fetal development. The most common anatomical site for the occurrence of branchial cleft cysts is in the cervical area, generally anterior to the sternomastoid muscle in the upper or middle portion of the neck. A mediastinal branchial cleft cyst is extremely rare and few cases have been reported. We report the case of branchial cleft cyst found in the anterior mediastinum with literature review.
Branchial Region
;
Branchioma
;
Fetal Development
;
Mediastinal Cyst
;
Mediastinum
;
Muscles
;
Neck
;
Thorax
;
Tomography, X-Ray Computed