1.External Cardiopulmonary Rususcitation for Cardiac Arrest: Case Report.
Chung Kie PARK ; Yung Dal PARK
Korean Journal of Anesthesiology 1969;2(1):65-70
Nine cases of cardiac arrest caused by various conditions and circumstances has been reported. 1. All of them were resuscitated by external cardiac massage but one of them had very poor physical; conditions because of delay in management. 4 cases made an uncomplicated recovery and 5 cases expired. Acute and chronic hypoxia was suspected as the most commoncause of cardiac arrest in these cases. 3. Of the expired 5 cases, intravenous injection of potassium chloride was suspected as the cause in one case. Another one was due to spinal anesthesia. 4. External cardiac massage might be an excellent method of cardiopulmonary resuscitation.
Anesthesia, Spinal
;
Anoxia
;
Cardiopulmonary Resuscitation
;
Heart Arrest*
;
Heart Massage
;
Injections, Intravenous
;
Potassium Chloride
2.Epidural Hypertonie Saline for Intractable Pain Associated with Malignancies.
Korean Journal of Anesthesiology 1972;5(2):163-164
To two patients suffering from intractable upper abdominal pain associated with recurrent carcinomatosis following previous gastrectcmy, 10 per cent saline solution was administered through an indwelling epidural (T 7-8) catheter. The results are as follows: 1) The method effectively relieved the pain in both patients. 2) The durations of pain relief were variable. It is noteworthy, however, that the method is. remarkably effective in relieving intractable pain associated with incurable malignancies. 3) The pain accompanying saline injection could be modified by prior administration of xylocaine through the same catheter. 4) The method was simple without complications, hence ambulatory application was possible.
Abdominal Pain
;
Carcinoma
;
Catheters
;
Humans
;
Lidocaine
;
Methods
;
Pain, Intractable*
;
Sodium Chloride
3.Misread Partial Airway Obstruction as a Muscle Paralysis of Parathion Poisoning: A Case Report.
Chung Kie PARK ; Kyoo Sub CHUNG ; Yung Dal PARK ; Soon Hyo CHUNG
Korean Journal of Anesthesiology 1969;2(1):71-74
A case of parathion poisoning has been reported; in which the symptoms of hypoxia resulted from partial airway obstruction, however this was mistaken for parathion poisoning, and the correct diagnosis was proved by removal of hard blood clot in the bronchial bifurcation. Conclusions were as follows: Adquate administration of PAM and atropine presented impressive response of symptoms. 2. Careful and frequent removal of secretion might be the most important problem especially in this poisoning. 3. Massive administration of antibiotics could prevent pulmonary complications. 4. Pulmonary edema, the most common complication, was not present.
Airway Obstruction*
;
Anoxia
;
Anti-Bacterial Agents
;
Atropine
;
Diagnosis
;
Paralysis*
;
Parathion*
;
Poisoning*
;
Pulmonary Edema
4.A Phase Contrast Microscopic Study on the Induction of Cellular Deformation in Mast Cells.
Kum Duck CHOI ; Yung Keun OH ; Dal Uck PARK ; Kyu Soon RHIM ; Tong Hun CHO
Yonsei Medical Journal 1966;7(1):1-6
The influence of colchicine, colcemid, ginseng-alcohol extract, saponin, garlic alcohol-ether extract, and X-irradiation on free floating peritoneal mast cells were studied in rats by means of a phase contrast microscope. After the intraperitoneal injection of colchicine or colcemid the mast cells of the albino rat peritoneal fluid show an altered morphology. Ginseng-alcohol extract, allicin extracted from garlic, and X-irradiation do not elicit this cytological response.Mast cells exposed to saponin exhibit a severe destruction and degranulation. The relation of the mast cell-damaging agents, metabolic poisons, and X1-irradiation to the mast cell response is discussed with reference to the morphological changes. These are compared with the data of Padawer (1960, 1966).
Animals
;
Colchicine/*pharmacology
;
Mast Cells/*drug effects/*radiation effects
;
Microscopy, Phase-Contrast
;
*Panax
;
Plant Extracts/pharmacology
;
*Plants, Medicinal
;
*Radiation Injuries, Experimental
;
Rats
;
Saponins/*pharmacology
5.Comparative Study of Spinal Anesthesia with 0.5 % Isobaric Bupivacaine and Hyperbaric T-caine.
Yung Kee KIM ; Byung Sik YU ; Un Joo PARK ; Chong Dal CHUNG ; Yong Il KIM ; Chong Han CHAE
Korean Journal of Anesthesiology 1990;23(5):769-774
In our hospital we studied the effects of spinal anesthesia with 0.5% isobarie bupivacaine and hyperbaric T-caine in 60 patients undergoing operation of lower abdomen or lower limbs. The following results were obtained. 1) Maximum level of sensory loss were similar in both groups, the time taken to it was significantly faster in the T-caine group but the duration was significantly longer in the bupivacaine group. 2) Onset time of motor blockade was significantly faster in the T-caine group but the duration was significantly longer in the bupivacaine. 3) The fall in blood pressure appeared faster in the T-caine group but no significant value of difference between the two groups. No significant changes were noted in the pulse rates. 4) Post spinal headache developed in 5 patients out of 60 patients (8.3%). With the results, we can assume that 0.5% isobaric bupivacaine is a good local anesthetic agent for spinal anesthesia in operations of the lower abdomen and lower limbs.
Abdomen
;
Anesthesia, Spinal*
;
Anesthetics
;
Blood Pressure
;
Bupivacaine*
;
Headache
;
Heart Rate
;
Humans
;
Lower Extremity
6.Prognostic Significance of Bcl-2 Expression in Ovarian Cancers.
Gu KONG ; Young Ha OH ; Chan Pil PARK ; Do Soo NAH ; Yung Jin MOON ; Kyung Tai KIM ; Youn Yeoung HWANG ; Jung Dal LEE
Korean Journal of Obstetrics and Gynecology 1997;40(10):2262-2268
The protein encoded by the Bcl-2 proto-oncogene has been shown to prolong cell su-rvival by preventing cell death(Apoptosis) induced by many insults including cancer therap-eutic drugs. Recently many researches have elucidated the bcl-2 expression in several hu-man solid cancers. However, there is still a few avaiable data to determine the role of Bcl-2 expression in the ovarian carcinogenesis and its prognostic significance in ovarian can-cers. Hence, we examined the expression of Bcl-2 in 68 ovarian epithelial cancers using immunohistochemistry and determined whether Bcl-2 expression has prognostic significance in the ovarian epithelial cancers. We found Bcl-2 expression(>5% positive cell) in 31 patients(40%). Bcl-2 expression were exclusively negative in the mucinous type of the ovarian epithelial cancer. Bcl-2 exp- ression was not correlated with tumor stage(stage I & II vs III & IV, p=0.63). The patients with Bcl-2 positivity had lower recurrence rate than the patients with negativity at the se- cond look operation(p<0.01). Although there was a trend that the patients with Bcl-2 posi- tivity had better acturial survival than the patient with negativity, the stastical significance was not present(3 years acturial survival;+vs-;63%, 29%;p>0.05). These results sug- gest the Bcl-2 expression appears an early event in the ovarian carcinogenesis and has an inhibiting role in progression of ovarian tumor.
Carcinogenesis
;
Humans
;
Immunohistochemistry
;
Mucins
;
Ovarian Neoplasms*
;
Proto-Oncogenes
;
Recurrence
7.Two Cases of Tuberous Sclerosis Associated with Subependymal Giant Cell Astrocytoma.
Yong KO ; Kwang Myung KIM ; Hwan Yung CHUNG ; Nam Kyu KIM ; Suk Jun OH ; Chan Geum PARK ; Jung Dal LEE ; Seung Ro LEE ; Chang Gok HAHM
Journal of Korean Neurosurgical Society 1988;17(3):535-544
Neurosurgical intervention in the syndrome is discussed in the light of two recently treated cases, one of which was admitted due to acute hydrocephalic attack, the other was confirmed by the typical computed tomographic findings as well as the classic triad of adenoma sebaceum, mental retardation and epilepsy. There cases had no family historty and were probably the result of new mutations and variable penetrance. Transcallosal microsurgical excision of tumor was accomplished in both cases and subependymal giant cell astrocytoma was confirmed. The hydrocephalus resolved but subduroperitoneal shunt was required in one case.
Astrocytoma*
;
Epilepsy
;
Humans
;
Hydrocephalus
;
Intellectual Disability
;
Penetrance
;
Tuberous Sclerosis*