1.Ethical Thinking on Doctor's selling Activities in Consulting Room
Chinese Medical Ethics 1995;0(03):-
The paper expounds the ethics problems caused by doctor's selling activities in consulting room,which means the conflicts between doctors and patients, purchase pressure implied in seeking medical ad vice, disgrace to the aim of medical service etc. Furthermore puts forward some suggestions about strengthening management, stopping doctors' selling activities:1. to curb doctors' selling activities in consulting room; 2. to formulate health law and regulations, standardize medical behavior; 3. to deepen health reformation, improve investment mechanism.
2.Effects of Chinese herbal medicine Yiqi Huayu formula on substance P expression in skin ulcers of rats with diabetes mellitus.
Journal of Integrative Medicine 2011;9(12):1367-72
To investigate the effects of Chinese herbs for replenishing qi (Yiqi) and dissolving stasis (Huayu) on substance P expression in granulation tissue of skin ulcers in rats with diabetes mellitus.
4.Surgical treatment for rectal prolapse
International Journal of Surgery 2010;37(11):747-749
Rectal prolapse is a rare disease, has been attracting many surgeons to study it.Surgical treatment of rectal prolapse is currently more than 50 kinds, most of which are modifications of several basic modes treatment, depending on the doctor' s grasp on the patient anatomy.Currently comprehensive treatment of a variety of therapies is a more ideal way for the treatment of rectal prolapse.
5.Effect of uncoupling protein 2 on activation of hepatic stellate cell in liver fibrosis of rats
Jianduo AN ; Ying JIANG ; Yunfei BAI ; Xuejiang WANG
Acta Anatomica Sinica 2014;(4):480-484
Objective To explore the role of uncoupling protein 2 ( UCP2) in the development of hepatic fibrosis and its molecular mechanism .Methods The CCl4-induced liver fibrosis rat model in vivo was established to observe the pathological changes of rat livers .The expression levels of UCP2 and p38 mitogen activated protein kinase (p38 MAPK) were detected by using the techniques of Western blotting , Real-time PCR and immunohistochemistry .The hepatic stellate cells ( HSC) were stimulated by CCl 4 and UCP2-specific inhibitor Genipin to mimic liver fibrosis in vitro.The expression levels of UCP2 and p38MAPK were determined by using Western blotting .Results We found that UCP2 and α-SMA expression levels increased significantly (P <0.05, n =10) in the liver of rats with CCl4-induced liver fibrosis when compared with that of the normal control rats in vivo.Similarly, the expression levels of UCP2 and p38 MAPK were up regulated (P <0.05, n=6) in CCl4-treated HSC cells in vitro.However, the expressions of UCP2 and p38 MAPK were down regulated (P <0.05, n=6) in genipin-treated HSC cells in vitro.Conclusion UCP2 is involved in liver fibrosis, and probably contributed to the activation and proliferation of hepatic stellate cells .
6.Mechanism on symbiosis of Oncomelania hupensis and Schistosoma j aponicum
Sijia LVQIU ; Yunfei ZHOU ; Shiping WANG
Chinese Journal of Zoonoses 2014;(12):1239-1244
ABSTRACT:As the only intermediate host of Schistosoma j aponicum ,Oncomelania hupensis is an important link of schis‐tosomiasis .It plays an important role in the transmission of schistosomiasis .This article mainly demonstrates the following as‐pects :the invasion of schistosome miracidium into O .hupensis ,the growth of sporocyst ,and the mature and escape of cercari‐ae ,which would provide laboratory data from literatures for revealing the symbiotic relationship between O .hupensis and S . japonicum .However ,the symbiotic relationship between O .hupensis and S .japonicum is too complex to description com‐pletely .Therefore ,the symbiotic relationship will be the focus of future research .
7.Clinic application of fetal testis transplantation with main vessel segment
Yunfei HU ; Linglong WANG ; Sixing YANG
Chinese Journal of Microsurgery 1998;0(01):-
Objective To investigate the value of the clinical application of fetal testis transplantation with main vessel segment. Methods The testicular transplantation were performed to cure 9 patients suffered from male hyponadism with the fetal testis with main vessel segment as donor tissue. Results Except one, 8 patients had a significantly increased level of serum testosterone, the male secondary sexual characteristics and the sexual desire were improved. The size of testis was larger than before operation. Conclusion Fetal testis transplantation with main vessel segment is a effective method to cure male hyponadism and has great value of clinical application.
8.Effects of adiponectin against hydrogen peroxide induced myocardial injury in cultured rat neonatal cardiomyocytes
Yunfei BIAN ; Hui WANG ; Chuanshi XIAO
Chinese Journal of Pathophysiology 2000;0(08):-
AIM:To observe the effects of adiponectin on injury of the 3-4 d SD rat cardiomyocytes induced by the intervention of H2O2.METHODS:Primary cardiomyocytes were obtained from neonatal rat and were cultured by enzymatic digestion methods.The molecular marker was observed by ?-actin immunocytochemistry.Primary cultured 3-4 d cells were used in experiment,and the injury model was established by H2O2,and adiponectin and Ara-A were used for pre-treatment before cell culture.The morphological change of cardiomyocytes was observed under electron microscope.The contents of LDH,MDA and the activity of SOD were measured.The apoptosis of cardiomyocytes was detected by agarose gel electrophoresis and Annexin V/PI staining with flow cytometry.RESULTS:Adiponectin pretreatment significantly decreased the release of LDH(P
9.Application of fingertip photoplethysmogram assessment of endothelial function in screening coronary heart disease patients
Yunfei WANG ; Daoyuan SI ; Ping YANG
Journal of Jilin University(Medicine Edition) 2016;42(5):1014-1018
Objective:To investigate the application of photoplethysmogram in analyzing the fingertip pulse amplitude volume (PAV)to evaluate the endothelial function in diagnosing coronary heart disease,and to clarify its relationship with the risk factors of cardiovascular diseases.Methods:Total 409 patients with chest pain accepted coronary angiography (CAG)were selected and diveded into positive group (CAG+)(n=288)and negative group (CAG-) (n = 121)according to angiographic results.Fingertip photoplethysmogram was used to analyze the fingertip PAV by the way of applying endothelial function diagnostic after reactive ischemia,and the relationship between the PAV value and the risk factors of coronary heart diseases was analyzed,and the critical reference value of prediction index of coronary heart disease was determined.The risk factors such as age,gender,serum total cholesterol (TC ), low density lipoprotein (LDL ), high density lipoprotein (HDL ), non-HDL, serum triglyceride (TG),hypertension,diabetes,smoking,family history of coronary heart disease,body mass index (BMI)of the subjects in various groups were analyzed,and the relationship between the risk factors of coronary heart disease and PAV was analyzed by Logistic regression analysis.Results:The PAV of patients in CAG+group was significantly lower than that in CAG-group (P <0.01).The peak point of PAV was<1.37,if PAV<1.37 was used to predict the coronary heart disease,the predictive sensitivity,the specificity,the positive prediction and the negative prediction were 74.65%,44.63%, 76.24%, and 42.52%.The Logistic regression analysis showed that PAV was negatively associated with hypertension,smoking history,TG (OR= 1.476,OR=2.002, OR = 1.844;P < 0.01 ). Conclusion: PAV is associated with coronary heart disease and its risk factors (hypertension,smoking history,TG),and PAV=1.37 can be used as the peak point to predict the coronary heart disease.
10.Clinical Observation on Hyperthrombinemia in Nephrosis Treated with Huangqi Xianlingpi Decoction Plus Hirudal Gelatin Pill
Yunfei GUO ; Xiaoping GE ; Yongjun WANG
Journal of Traditional Chinese Medicine 1993;0(05):-
The biochemical and other lab indices of blood in 35 cases of nephrosis syndrome (NS) treated with Huangqi Xianlingpi Decoction plus Hirudo (HQXL) were observed. The results that HQXL was capable of decreasing urine protein, increasing plasma protein, lowering blood lipids (P