1.Pathologic diagnosis and prognosis of uterine leiomyosarcoma.
Chinese Journal of Pathology 2006;35(12):711-713
Female
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Humans
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Leiomyosarcoma
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diagnosis
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Mitotic Index
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Prognosis
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Uterine Neoplasms
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diagnosis
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Uterus
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pathology
2.Uterine smooth muscle tumors: relationship between morphology and biologic behavior.
Chinese Journal of Pathology 2011;40(8):505-507
Cell Nucleus Division
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Cyclin-Dependent Kinase Inhibitor p16
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metabolism
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Diagnosis, Differential
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Female
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Humans
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Leiomyoma
;
metabolism
;
pathology
;
physiopathology
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Smooth Muscle Tumor
;
metabolism
;
pathology
;
physiopathology
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Uterine Neoplasms
;
metabolism
;
pathology
;
physiopathology
4.Problems in the diagnosis of thyroid papillary and follicular carcinoma.
Chinese Journal of Pathology 2007;36(4):220-223
Adenocarcinoma, Follicular
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diagnosis
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pathology
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Adenoma
;
diagnosis
;
pathology
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Carcinoma, Papillary
;
diagnosis
;
pathology
;
Carcinoma, Papillary, Follicular
;
diagnosis
;
pathology
;
Cell Nucleus
;
pathology
;
Diagnosis, Differential
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Humans
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Neoplasm Invasiveness
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Thyroid Gland
;
pathology
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Thyroid Neoplasms
;
diagnosis
;
pathology
;
Thyroid Nodule
;
diagnosis
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Thyroiditis
;
diagnosis
5.Vulval intraepithelial neoplasia.
Chinese Journal of Pathology 2009;38(9):577-579
Carcinoma in Situ
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pathology
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virology
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Carcinoma, Squamous Cell
;
pathology
;
virology
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Diagnosis, Differential
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Female
;
Humans
;
Paget Disease, Extramammary
;
pathology
;
virology
;
Papillomavirus Infections
;
Precancerous Conditions
;
pathology
;
virology
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Vulvar Neoplasms
;
classification
;
pathology
;
virology
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Warts
;
pathology
;
virology
7.Modulatoin of Macrophage-Mediated Cytotoxic Activity Thibitory Effect of a Mycotoxin, Fusarin C, on Macrophage Activation in Mice
Zhong-Yun DONG ; You-Hui ZHANG ;
Chinese Journal of Immunology 1985;0(06):-
The effect of Fusarin C, a new mutagen extracted from Fusarium moniliforme,on murine peritoneal M? activation by measuring M?-mediated MTC ADCC and CS,Fusarin C could inhibit M? activation by both MAF and FDP. The inhibitory effect was dose-and time-dependent and the curves of dose-and time-response were similar in all three assays. There is, however, apparent difference in Fusarin C dose and time needed to induce significant in hibition among these assays. Significant inhibition occured at 0.4?g/ml and 0.5?g/ml for MTC and CS respectively, but 1.6?g/ml for ADCC. Similarly, the minimal period of time necessary to bring about significant inhibition was 2 hr for MTC, but 3 hr for ADCC. Finally, significance of the inhibitory effect of Fusarin C on M? anti-tumor activity in relation to carcinogenesis was discussed.
8.Modulation of macrophage-mediated cytotoxic activity Ⅱ.The Inhibitory effect of fusarin C on macrophage activation is reversible
Zhong-Yun DONG ; You-Hui ZHANG ;
Chinese Journal of Immunology 1985;0(01):-
The inhibitory effect of Fusarin C,a new mutagen isolated from Fusarium moniliforme,on M? activation was investigated.The inhibitory effect of Fusarin C disappeared partially after 24 hr culture in the absence of the mycotoxin and completely after 72 hr.In addition,it could be overcome by high concentrations of M? activating factor or anti-serum to the target cells.
9.Follow-up study on neuropsychological behavior development of preterm and low birth weight infants
Yanjuan WANG ; Qing PAN ; Nan ZHONG ; Yun LU ; Hui WANG
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(9):842-846
Objective To study the neuropsychological behavior development of preterm infants and low birth weight infants,and to provide a reference to the early prevention and intervention on developmental retardations.Methods A total of 101 preterm infants and/or low birth weight infants received the infant development test of 0 ~ 6 year-old children intelligence developmental scale for neurological development and autism behavior checklist(ABC).Results 25 boys and 5 girls suffered from different psychological mental disorders.The occurrences were as follows:10 cases with mental retardation,9 cases with the language development delay,9 cases with motor retardation,1 case with cerebral palsy and 1 case with autism spectrum disorder.The incidence of intelligence problems were that language retardation (18.9%),the fine motor (16.8%),the adapative ability (12.6%),social action (9.5 %) and the motor delay (3.2%).There were significant differences in the scores of social communication(x2=8.88,P=0.003),adaptive ability(x2=7.41,P=0.007),the fine motor(x2 =6.22,P=0.01) and total developmental quotient(x2 =5.58,P=0.02) between city children'and rural area.The behavioral problems more consisted in self-care ability and language retardation.Conclusion Preterm infants and low birth weight infants are exposed to language,fine motor,adaptive and communication ability problems,especially the children living in country.It is necessary to improve the early education and intervention for the rural preterm infants and low birth weight infants.
10.Effect of sodium houttuyfonate in enhancing imipenem's activity against Pseudomonas aeruginosa biofilms.
Hui-Juan CHENG ; Min YANG ; Chang-Zhong WANG ; Chang-Feng ZHANG ; Chun-Yun CHU
China Journal of Chinese Materia Medica 2014;39(2):296-299
OBJECTIVETo investigate the resistant effect of houttuyfonate sodium (SH) combined with imipenem (IMP) against Pseudomonas aeruginosa (Pa) biofilms.
METHODThe two-fold dilution method was used to examine the minimum inhibitory concentration (MIC) of the tested drug. The crystal violet staining was applied to detect the effect of the combination of 1/2MIC, 1MIC, 2MIC of SH, single IMP, 1/2MIC of SH and IMP of various concentrations on the clearance rate of adherent bacteria, growth of biofilms and alginate production. Fluorescein diacetate (FDA)-propidium iodide (PI) doubling staining assay was employed to observe the bacterial viability and morphological changes after membrane dispersion of each drug group.
RESULTSodium houttuyfonate could enhance the effect of IMP against pseudomonas aeruginosa biofilms. Particularly, the combination group with the concentration of 2MIC showed the highest effect, with P < 0.001 compared with the negative control group. The above results were proved by the bacterial viability and biofilm morphology under fluorescence microscope.
CONCLUSIONAfter being combined with imipenem, sodium houttuyfonate shows a higher effect against biofilms. It is expected that the combination of the two drugs could improve the clinical efficacy of associated infections.
Alkanes ; pharmacology ; Biofilms ; drug effects ; growth & development ; Drug Synergism ; Imipenem ; pharmacology ; Microbial Sensitivity Tests ; Microbial Viability ; drug effects ; Pseudomonas aeruginosa ; drug effects ; physiology ; Sulfites ; pharmacology