1.Susceptibility to Antivirals of a Human HBV Strain with Mutations Conferring Resistance to Both Lamivudine and Adefovi.
Yun Jung CHANG ; Myung Seok LEE
The Korean Journal of Gastroenterology 2005;46(4):316-317
No abstract availble
2.Biliary Tract & Pancreas; Effectiveness of Endoscopic Ultrasonography in Detecting the Extrahepatic Choledocholithiasis.
Im Hwan ROE ; Jung Taik KIM ; Il Han SONG ; Jung Won KIM ; Yun Soo YUN ; Chang Young LIM
Korean Journal of Gastrointestinal Endoscopy 1997;17(1):23-31
BACKGROUND/AIMS: Ultrasonography is the easiest, fastest procedure for the diagnosis of choledocholithiasis, but the diagnostic failure are mostly because of the intrapancreatic level of this condition and the absence of bile duct dillatation. Endoscopic ultrasonography is a promising procedure for the diagnosis of extrahepatic cholestasis due to noninvasiveness and accuracy in the digestive gas interposition. The aim of this study was to prospectively compare the diagnostic accuracy of endoscopie ultrasonography with abdominal ultrasonography and endoscopic retrograde cholangiography in 66 patients with suspected choledocholithiasis. METHODS: All of the patients had abdominal ultrasonography, endoscopic ultrasonography ~and endoscopie retrograde cholangiography within 72 hours and final diagnosis was determined by endoseopic retrograde cholangiography with sphincterotomy. RESULTS: (l) Choledocholithiasis was confirmed in 45 patients: Thirteen patients had nondilated common bile ducts and 20 patients had stones with diamerer < 1 cm. (2) Endoscopic ultrasonography was more sensitive(95.5%) than abdominal ultrasonography (44.4%: P<0.0001) and similar to endoscopic retrograde cholangiography (97.8%). Specificity was same as 100% in 3 diagnostic tools. (3) Endoscopic ultrasonography was superior to abdommal ultrasonography for the diagnosis of choledocholithiasis with nondilated common bile duct(100% vs 15.3%, P<0.0001) and with less than 1cm sized small stone(100% vs 10.0%, P<0.0001). Endoscopic ultrasonography results did not depend on stone diameter or common bile duct dilatation. CONCLUSIONS: Endoscopic ultrasonography could be an accurate and safe diagnostic tool for the diagnosis of choledocholithiasis and could be promising especially in the cases with difficult cannulation of bile duct and gal1 stone pancreatitis.
Bile
;
Bile Ducts
;
Biliary Tract*
;
Catheterization
;
Cholangiography
;
Choledocholithiasis*
;
Cholestasis, Extrahepatic
;
Common Bile Duct
;
Diagnosis
;
Dilatation
;
Endosonography*
;
Humans
;
Pancreas*
;
Pancreatitis
;
Prospective Studies
;
Sensitivity and Specificity
;
Ultrasonography
3.Erratum: Impact of Meconium Obstruction-Related Risk Factors on Surgical Intervention in Very Low Birth Weight Infants.
Hyun Sop KWON ; Ji Mi JUNG ; Yun Jung LIM ; So Hyun NAM ; Gina LIM ; Mi Lim CHUNG
Neonatal Medicine 2015;22(3):182-182
We found an error in this article.
4.A Pilot Survey of Difficult Intubation and Cannot Intubate, Cannot Ventilate Situations in Korea.
Jung Soo KIM ; Hyun Kyoung LIM ; Jeong Yun SONG ; Hyun Keun LIM ; Kyungchul SONG ; Jae Hwa CHO
Korean Journal of Critical Care Medicine 2016;31(3):202-207
BACKGROUND: There have been no studies of airway management strategies for difficult intubation and cannot intubate, cannot ventilate (CICV) situations in Korea. This study was intended to survey devices or methods that Korean anesthesiologists and intensivists prefer in difficult intubation and CICV situations. METHODS: A face-to-face questionnaire that consisted of a doctor's preference, experience and comfort level for alternative airway management devices was presented to anesthesiologists and intensivists at study meetings and conferences from October 2014 to December 2014. RESULTS: We received 218 completed questionnaires. In regards to difficult intubation, the order of preferred alternative airway devices was a videolaryngoscope (51.8%), an optical stylet (22.9%), an intubating laryngeal mask airway (11.5%), and a fiber-optic bronchoscope (10.6%). One hundred forty-two (65.1%) respondents had encountered CICV situations, and most of the cases were identified during elective surgery. In CICV situations, the order of preferred methods of infraglottic airway management was cricothyroidotomy (CT) by intravenous (IV) catheter (57.3%), tracheostomy by a surgeon (18.8%), wire-guided CT (18.8%), CT using a bougie (2.8%), and open surgery CT using a scalpel (2.3%). Ninety-eight (45%) of the 218 respondents were familiar with the American Society of Anesthesiologists' difficult airway algorithm or Difficult Airway Society algorithm, and only 43 (19.7%) had participated in airway workshops within the past five years. CONCLUSION: The videolaryngoscope was the most preferred device for difficult airways. In CICV situations, the method of CT via an IV catheter was the most frequently used, followed by wire-guided CT method and tracheostomy by the attending surgeon.
Airway Management
;
Bronchoscopes
;
Catheters
;
Congresses as Topic
;
Education
;
Intubation*
;
Intubation, Intratracheal
;
Korea*
;
Laryngeal Masks
;
Methods
;
Surveys and Questionnaires
;
Tracheostomy
5.A Clinical Study on Coenzyme Q10(Neuquinon(R)) in the Treatment of Congestive Heart Failure.
Jeong Hyun KIM ; Jong Yoon LIM ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1979;9(1):17-22
Coenzyme Q is concentrated in Golgi apparatus membranes and mitochondria, but not in other membranes. Although it is difficult to prove the metabolic action of coenzyme Q administered exogenously in clinical cases, the effect of this substance can be evaluated by criteria based on clinical findings. In an attempt to evaluate the effect of coenzyme Q for the treatment of 67 patients(male 26 cases, female 41 cases) of congestive heart failure, we administered Coenzyme Q1030mg daily for 4 to 8 weeks. Most of them were valvular heart disease(74.6%) and hypertension (14.9%). Clinical effects were evaluated at least 4 weeks later by the criteria using a scoring method of severity of congestive heart failure which was devised by Ishiyama, etc. In summary, a definite effect was found in 13 cases(19%) and a mild effect was observed in 46 cases(69%). During treatment there were no significant side effects, and also no significant changes in heart rate and blood pressure.
Blood Pressure
;
Estrogens, Conjugated (USP)*
;
Female
;
Golgi Apparatus
;
Heart
;
Heart Failure*
;
Heart Rate
;
Humans
;
Hypertension
;
Membranes
;
Mitochondria
;
Research Design
;
Ubiquinone
6.A Study on Relation betwen Red Cell Electrolyte Concentractions and Serum Digoxin Level.
Seong Yun KIM ; Jung Kun LIM ; Ye Hwe KIM ; Young Woo LEE ; Sung Ho LEE
Korean Circulation Journal 1981;11(1):69-86
For the purpose of elucidating relation between red cell electrolyte concentrations and serum digoxin level, measurement of red cell electrolyte concentrations and seum digoxin level by radioimmunoassay were done in 46 normal controls and 63 patients of CHF including 8 patients with digitalis intoxication. The results obtained were as follows: 1. Red cell sodium concentration and ratio of red cell sodium to red cell potassium concentration in normal males were significantly higher than those of females, and red cell potassium concentration in normal males was significantly lower than that of normal females. 2. Red cell potassium concentration in patients of CHF was significantly higher than that of normal controls, but there was no difference in the red cell sodium concentration between the groups. 3. There was no relation between red cell electrolyte concentrations and serum digoxin level, and red cell electrolyte concentration did not exactly estimate serum digoxin level. 4. Red cell electrolyte concentrations in the patient of CHF were valuable in detecting digitalis toxicity.
Digitalis
;
Digoxin*
;
Female
;
Humans
;
Male
;
Potassium
;
Radioimmunoassay
;
Sodium
7.Factors Influencing Intention for Human Papillomavirus Vaccination Among Parents with Elementary School Girls.
Journal of Korean Academic Society of Nursing Education 2017;23(4):367-377
PURPOSE: This descriptive research study aims to investigate influential factors on human papillomavirus vaccines, among parents who have elementary school daughters. METHODS: This study was conducted with 210 parents whose children are elementary school girls, aged 9 to 12 years, in G Metropolitan City. Data were collected from August 17 to September 12, 2015 using structured questionnaires. A descriptive statistical analysis, a t-test, a χ2-test, a Fisher's exact test, and a logistic regression using SPSS/WIN 21.0. RESULTS: The influential factors on the human papillomavirus vaccination intention were confirmed to be three variables: cervical cancer knowledge, perceived sensitivity, and perceived barriers. CONCLUSION: An intervention program, both to increase the sensitivity of vaccination and to decrease barriers, should be developed so as to improve parents' health beliefs towards human papillomavirus vaccination.
Child
;
Female*
;
Humans*
;
Intention*
;
Logistic Models
;
Nuclear Family
;
Papilloma
;
Papillomavirus Vaccines
;
Parents*
;
Uterine Cervical Neoplasms
;
Vaccination*
8.A Study on the Serologic Parameters in Petients with Anemia of Chronic Renal Failure-According to Erythropoietin Treatment.
Jong Sik LIM ; Ho Jung KANG ; Won Jong PARK ; Jun Young DO ; Kyeung Woo YUN
Yeungnam University Journal of Medicine 1994;11(1):82-93
Clinical study was carried out on the 64 hemodialysis patients(HD) with chronic renal failure who had been treated from December 1992 to July 1993 in Yeungnam University Hospital. The following results were obitained. In hematologic parameters, MCH was 28.8±2.0pg, and MCV was 92.4±4.7fl. Result revealed normochromic and normocytic anemia. Mean values of serum ferritin were 657.4±292.0ng/ml in men and 511.5±370g in women. Mean values of serum iron were 145.5±63.7µg/dl. Mean values of transferrin saturation was 61.6±28.4%. Serum frerritin, serum iron and transferrin saturation were higher in HD group than normal reference. In erythropoeitin treatment group, Hb and Hct were significantly higher than non-erythropoietin treatment group. Amount of transfusion was significantly higher in non-erythropoietin treatment group than erythropoeitin treatment group(p<0.05). Values of iron, transferrin saturation were significantly higher in abnormal liver function test(LFT0 hemodialysis group than normal LFT group(p<0.05). Transfusion amounts revealed positive correlation with ferritin(r=0.4675), transferrin satruation (r=0.3823) and iron(r=0.3386) (p<0.05).
Anemia*
;
Clinical Study
;
Erythropoietin*
;
Female
;
Ferritins
;
Humans
;
Iron
;
Kidney Failure, Chronic
;
Liver
;
Male
;
Renal Dialysis
;
Transferrin
9.The relationship between neonatal hypoglycemia and newborn iron status in hypoglycemic large-for-gestational age infants.
Myung Ja YUN ; In Ho SONG ; Hye Lim JUNG ; Dong Hyuck KUM
Journal of the Korean Pediatric Society 1992;35(12):1667-1673
No abstract available.
Humans
;
Hypoglycemia*
;
Infant*
;
Infant, Newborn*
;
Iron*
10.Clinical Outcomes of Initial Dexamethasone Treatment Combined with a Single High Dose of Intravenous Immunoglobulin for Primary Treatment of Kawasaki Disease.
Yonsei Medical Journal 2014;55(5):1260-1266
PURPOSE: To investigate the clinical effects of a single high dose intravenous immunoglobulin (IVIG) combined with initial dexamethasone as a primary treatment on Kawasaki disease (KD). MATERIALS AND METHODS: Between January 2008 and December 2010, we reviewed the medical records of 216 patients with complete KD patients that were admitted to a single medical center. 106 patients were treated with a single high dose of IVIG (2 g/kg) alone and 110 patients received IVIG and dexamethasone (0.3 mg/kg per day for three days). RESULTS: The combined IVIG plus dexamethasone patient group had a significantly shorter febrile period and duration of hospital stay (1.4+/-0.7 days vs. 2.0+/-1.2 days, p<0.001; 5.8+/-1.7 days vs. 6.9+/-2.5 days, p<0.001, respectively) than the IVIG alone group. The combined IVIG plus dexamethasone group required IVIG retreatment significantly less than the IVIG only group (12.7% vs. 32%, p=0.003). After completion of the initial IVIG, C-reactive protein levels in the combined IVIG plus dexamethasone group were significantly lower than those in the IVIG only group (2.7+/-4.0 mg/dL vs. 4.6+/-8.7 mg/dL, p=0.03). In the combined IVIG plus dexamethasone group, the incidence of coronary artery lesions tended to be lower without worse outcomes at admission after initial infusion of IVIG and in follow-up at two months; however, the differences were not significant (8.2% vs. 11.3%, p=0.22; 0.9% vs. 2.8%, p=0.29). CONCLUSION: Initial combined therapy with dexamethasone and a single high-dose of IVIG resulted in an improved clinical course, in particular a shorter febrile period, less IVIG retreatment, and shorter hospital stay without worse coronary outcomes.
Child, Preschool
;
Dexamethasone/administration & dosage/adverse effects/*therapeutic use
;
Female
;
Fever/drug therapy
;
Glucocorticoids/administration & dosage/adverse effects/*therapeutic use
;
Humans
;
Immunoglobulins, Intravenous/administration & dosage/adverse effects/therapeutic use
;
Immunologic Factors/administration & dosage/adverse effects/*therapeutic use
;
Infant
;
Length of Stay
;
Male
;
Mucocutaneous Lymph Node Syndrome/*drug therapy
;
Treatment Outcome