1.Ischemic stroke following acute myocardial infarction
Yun LU ; Muhui LIN ; Xiaohong CHEN
International Journal of Cerebrovascular Diseases 2012;20(8):608-612
Myocardial infarction and ischemic stroke share many common risk factors.Their pathophysiological processes are also similar and the 2 diseases often occur at the same time.Coronary artery disease is one of the important causes of embolic stroke in the elderly population.However,there are a few reported stroke events available after myocardial infarction.This article reviews ischenic stroke following acute myocardial infarction.
2.Comparison of coronary artery bypass graft with percutaneous coronary intervention with bare mental stents or sirolimus eluting stents for left main coronary artery disease
Yun LIN ; Yundai CHEN ; Xiantao SONG
Chinese Journal of Interventional Cardiology 1996;0(04):-
Objective To evaluate the clinical outcomes of consecutive unselected patients treated with coronary artery bypass graft surgery or percutaneous coronary intervention with bare mental stents or sirolimus eluting stents for left main artery disease。Methods From 1995 to 2005,415 patients with left main artery disease received revascularization therapies in which 196 subjects received CABG procedure,and 97 subjects received BMS therapies from October,1995 to August,2003,and 122 subjects received SES therapies from September,2003 to May,2005.Results Rate of diabetes mellitus cormorbidity in CABG group was higher than that in BMS group and SES group,but the cormorbidity rates of renal insufficiency,stroke and pulmonary insufficiency in CABG group were lower than those in BMS group and SES group.The 30-day major adverse cardiac and cerebrovascular events in BMS group,SES group and CABG group was 3.09%,4.01% and 10.71% respectively(P
3.Outcome of donor bone after vascularized allograft bone transplantation
Yun XIE ; Zhenguang CHEN ; Jianhua LIN
Chinese Journal of Tissue Engineering Research 2007;0(04):-
AIM: To observe the outcome of donor bone after vascularized allograft bone transplantation under immunoregulation. METHODS: The experiment was conducted at the Microsurgery Institute, Medical College, Wuhan University from December 2002 to March 2004. Totally 21 male flap-eared Japanese rabbits were selected as donor and 42 female ones as recipients. Recipients were composed of 21 rabbits in the experimental group and 21 rabbits in the control group. ①Anastomotic vascularized massive shaft of femur allograft was performed in Japanese flap-eared rabbits of either sex. ②The experimental animals were assigned into experimental group (treated with ciclosporin A, 25 mg orally, once a day, for 3 weeks) and control group (no any immunosuppressive agent). ③X-ray and histology examinations were performed at months 1, 4 and 9 after operation. Bone grafts were analyzed with Sry semi-quantitative polymerase chain reaction. RESULTS: A total of 42 rabbits were involved in the result analysis. ①X-ray manifestation at different time points after rabbit transplantation in the two groups: X-ray showed typical fracture healing mode at different phases after operation in the experimental group, whereas the increase of bone graft density, and around by a mass of bony callus in the control group. ②Histology manifestation of rabbits in the two groups after operation: At different time phases it showed typical fracture healing mode in the experimental group after operation, and 9 months later the marrow cavity was filled with myeloid tissues, and the internal and external cortex was flat; Haversian canal had revered to the normal size; Bone cells appeared in the bone lacuna; Peripheral cortex was wrapped with fibrous tissues. In the control group, it showed inflammatory cell infiltration with rejection, bone marrow necrosis in marrow cavity, formation of fibra tissues, bone cell loss in bone lacuna, and the bone grafts were wrapped with woven bone that was from recipients. ③Outcome of Sry semi-quantitative PCR analysis: The Sry semi-quantitative PCR analysis showed that the relation between the ratio of male DNA and the postoperative period was positive; the ratio of experimental group at month 9 postoperative was near to 100%, while control group only reached 11.8%. CONCLUSION: Under the immunoregulation, bone graft can unite with the recipient bone in an earlier postoperative period and replace by recipient bone rapidly in vascularized allograft bone transplantation.
4.Clinical study of pancreatic lymphoma presenting as acute pancreatitis
Shuang QU ; Lisheng LIAO ; Yun LIN ; Biyun CHEN ; Weimin CHEN
Journal of Leukemia & Lymphoma 2013;22(11):665-667,670
Objective To analyze the clinical features and diagnosis-treatment of pancreatic lymphoma presenting as acute pancreatitis.Methods The clinical records of 7 patients including laboratory findings were retrospectively reviewed.Some related medical literatures were reviewed.Results Seven patients presented acute abdominal pain.Laboratory findings revealed significant increase of serum amylase and lipase levels.CT scan of the abdomen or PET-CT showed a diffuse swelling of the pancreas or masses in the body or tail.Extrapancreatic spread such as bone,bone marrow,spleen infiltrate was found out in 5 patients.Of the 7 patients,6 were diagnosed as the diffuse large B-cell lymphoma,1 as the anaplastic large cell lymphoma.Six patients underwent systematic chemotherapy.Two died and the others received complete or part remission.Conclusion Pancreatic lymphoma is uncommon and represents a rare cause of acute pancreatitis.It needs to be confirmed by histopathologic examination.The standard treatment is not only for acute pancreatitis,but also for NHL including CHOP or CHOP-like chemotherapy.
5.Eleven cases of drug-induced arsenic poisoning.
Da-wei LIN ; Yan-jie PENG ; Chen-yun YANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2005;23(3):227-227
Adult
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Aged
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Arsenic Poisoning
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drug therapy
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etiology
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Drugs, Chinese Herbal
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adverse effects
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Female
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Humans
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Male
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Middle Aged
8.Effect of xingding injection on platelet coagulation and fibrinolysis activity in patients with advanced stage chronic pulmonary heart disease.
Bi-yun SUN ; Jing-lin YANG ; Xue-ying CHEN
Chinese Journal of Integrated Traditional and Western Medicine 2004;24(2):154-155
Aged
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Aged, 80 and over
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Drugs, Chinese Herbal
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therapeutic use
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Female
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Fibrin Fibrinogen Degradation Products
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metabolism
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Fibrinolysis
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drug effects
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Glycoproteins
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blood
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Humans
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Injections
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Male
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Middle Aged
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Phytotherapy
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Plasminogen Activator Inhibitor 1
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blood
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Platelet Aggregation
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drug effects
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Pulmonary Heart Disease
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blood
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drug therapy
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Tissue Plasminogen Activator
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blood
9.Study on determining method of dl-tetrahydropalmatine by TLCS
Xin LIU ; Yu LIN ; Yun CHEN ; Junxuan YANG ; Wenyin PEN
Chinese Traditional Patent Medicine 1992;0(01):-
AIM: To study the determination of dl-tetrahydropalmatine (THP) in Chi nese traditional patent medicines by TLC-Scanning from the viewpoint of the pro cess control of manufacture. METHODS: To select the 5 kinds of representative drugs and its prep arations contained, THP was extracted with solvent method. The mobile phase contains diethylamine. THP w as separated with high-efficiency silica gel plate or handcrafted silica gel p late. Iodine was used for chronogenic agent and fluorescence defectiion for dete rmination. TLC-Scanning results were compared with HPLC. RESULTS: The method is practicable, the result is correlative with the HPLC. CONCLUSION: TLC-Scanning is fit for the quality control of the Chi nese traditional patent medicine in the process of manufacture.
10.Survey and analysis on medical expenses of inpatients in Haikou city
Lin CHEN ; Guojun LIU ; Qionghua XU ; Jianhong LI ; Tianzhen YUN
Chongqing Medicine 2015;(10):1383-1385
Objective To understand the basic situation and the influencing factors of medical expenses of the inpatients in Haikou city for the government to developing a scientific control policy of medical expense or improving the existing measures for controlling the medical expense.Methods Totally 463 inpatients from 10 hospitals were conducted the questionnaire survey and the survey data were analyzed.Results The difference of medical costs constituent existed in different medical institutions and the me-dian of drug costs to the total medical costs in general hospital was 42.13%.30.02% (139/463)of the surveyed inpatients thought that the use of “new techniques,new drugs and new equipments”was the primary cause of medical costs rising.51.19%(237/463) of patients thought that the primary considered factor is “cure”when seeing a doctor.24.84%(115/463)of patients did not known the modification of medical insurance policy.46.00%(213/463)and 28.51%(132/463)of patients thought that the main responsi-bility main body for controlling the medical costs rising is government and hospital respectively.Conclusion Increasing the medical insurance policy advocacy,promoting the reform of medical insurance payment methods,strengthening the dominant position of gov-ernment control medical costs and rationally allocating the medical resources conduce to reduce the medical costs rising.