1.Correction of vermilion border malformation with a sliding subcutaneous pedicle flap.
Sheng BI ; Zhen-xiang WANG ; Dong-yun YANG
Chinese Journal of Stomatology 2012;47(2):127-128
Adolescent
;
Adult
;
Cleft Lip
;
surgery
;
Female
;
Humans
;
Lip
;
injuries
;
surgery
;
Male
;
Middle Aged
;
Postoperative Complications
;
Reconstructive Surgical Procedures
;
methods
;
Surgical Flaps
;
Young Adult
2.Structural equation model analysis of risk factors for low back pain among greenhouse vegetable-planting farmers.
Hong-yun DONG ; Xi-wei YANG ; Sujang YU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2013;31(5):366-368
OBJECTIVETo explore the risk factors of low back pain (LBP) among greenhouse vegetable planting farmers and estimate the level of the effects.
METHODSA self-made questionnaire based on the Dutch Musculoskeletal Questionnaire and the Nordic Questionnaire was conducted to 639 greenhouse vegetable planting farmers and then structural equation model was used to analyze the risk factors of LBP in SmartPLS software.
RESULTSThe coefficient of determination of the model was 0.827, and the structural coefficients of dynamic loads, static loads, force exertion, ergonomic environment and repetitive loads on LBP were 0.21, 0.43,0.27, 0.045 and 0.034 respectively, and the total effects of the above latent variables on LBP were 0.21, 0.43,0.27, 0.33 and 0.034 respectively.
CONCLUSIONThe main risk factors of LBP among greenhouse vegetable planting farmers were static loads, ergonomic environment, force exertion and dynamic loads.
Adult ; Female ; Humans ; Low Back Pain ; etiology ; Male ; Middle Aged ; Occupational Diseases ; etiology ; Risk Factors ; Surveys and Questionnaires ; Vegetables
3.Hedgehog signaling pathway in chemocarcinogenesis and progression of breast cancer
Dong CUL ; Linqing YANG ; Yun HE ; Zhixiong ZHUANG
Chinese Journal of Pharmacology and Toxicology 2015;(2):328-332
The controversial results of several studies suggest that certain everyday-use chemicals may be linked to breast cancer. ln recent years, extensive researches have been carried out to under-stand breast carcinogenesis and the hedgehog(Hh) signaling pathway has emerged as a critical determi-nant of human breast cancer. Aberrant Hh signaling in adults results in carcinogenesis, angiogenesis, and metastasis. This review is focused on the Hh signaling pathway and chemicals in the regulation of breast cancer development and provide an updated survey of pre-clinical and clinical trials of novel strategies to target them.
4.Relationship between renal pathology and clinical manifestations in children with Henoch - Schonlein purpura nephritis
Daliang XU ; Yun WANG ; Qiaozhi YANG ; Xiaoshan SHAO ; Ying ZHU ; Shaohan FANG ; Yang DONG
Chinese Journal of Applied Clinical Pediatrics 2015;(21):1622-1625
Objective To investigate the correlations between the clinical manifestations based on pathologic grades and renal pathological features of Henoch - Schonlein purpura nephritis(HSPN)in children. Methods The clinical data of 77 patients with HSPN in the Department of Nephrology,Anhui Provincial Children's Hospital from Ja-nuary 2004 to March 2014 were retrospectively analyzed. The relationship between clinical manifestation and pathologi-cal features was analyzed. Results Among the 77 patients,21 cases(27. 3% )had both abdominal symptoms,and ar-thritis was reported in 15 cases(19. 5% ),28 cases(36. 4% )had abdominal symptoms and arthritis,and 13 cases (16. 9% )had no such symptoms. Hematuria and proteinuria were the most common clinical types[48. 1%(37 / 77 ca-ses)],followed by simple hematuria or proteinuria[27. 3%(21 / 77 cases)],nephrotic syndrome[23. 4%(18 / 77 ca-ses)],and chronic nephritis[1. 3%(1 / 77 cases)]. The major of pathological changes in HSPN were grade Ⅱ[46. 8%(36 / 77 cases)]and grade Ⅲ[45. 5%(35 / 77 cases)],the minority of them were grade Ⅰ[6. 5%(5 / 77 cases)]and grade Ⅳ[1. 3%(1 / 77 cases)]. The severity of urine protein was positively associated with pathologic classification (r s = 0. 472,P = 0. 000). According to the glomerular deposition of immune complex,there were 6 types. The percen-tage of deposition of IgA + IgM was 62. 3%(48 / 77 cases),IgA + IgG + IgM was 19. 5%(15 / 77 cases),IgA 14. 3%(11 / 77 cases),that of IgA + IgG 1. 3%(1 / 77 cases),and the IgM 1. 3%(1 / 77 cases),no Ig 1. 3%(1 / 77 cases). In these cases,76. 6%(59 / 77 cases)had complements C3 deposition;pathologic stage characterized by Ⅲ level and a-bove were common[54. 2%(32 / 59 cases)],Ⅱ level 42. 2%(25 / 29 cases),Ⅰ level 3. 4%(2 / 59 cases). Among the different types of immune complex depositions,there was no statistically significant difference in pathological types of distribution,while the clinical type and complements C3 deposition were significantly associated with pathologic classifi-cation(rs = 0. 361,P = 0. 001). Sixty - two cases were rated as level 1(80. 5% ),and 15 cases was level 2(19. 5% );in different clinical group,rating in glomeruli was statistically different(χ2 = 17. 2,P = 0. 004). Renal tubular interstitial rating of all the patients were level 1(100% ). Conclusions The severity of urine protein,complements C3 deposition is associated with pathologic classification. Pathologic classification can basically reflect the renal damage in HSPN.
5.Three Cases of Idiopathic Hypertrophic Subaortic Stenosis.
Sei Weon YANG ; Dong Gyoon KIM ; Jong Jin SEO ; Jung Yun CHOI ; Yong Soo YUN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1984;27(5):493-500
No abstract available.
Cardiomyopathy, Hypertrophic*
6.46 cases of aplastic anemia caused by benzene.
Yun-fang YANG ; Jun-bin GUO ; Wan-sao XIE ; Mei-yun SU ; Zai-you DAI ; You-ting DONG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2003;21(3):238-238
Adolescent
;
Adult
;
Anemia, Aplastic
;
etiology
;
therapy
;
Benzene
;
poisoning
;
Bone Marrow Cells
;
drug effects
;
pathology
;
Female
;
Humans
;
Male
;
Occupational Diseases
;
etiology
;
therapy
;
Occupational Exposure
;
adverse effects
8.Serum Ghrelin Concentrations in Type 2 Diabetes Mellitus.
Yong Seok JANG ; Dong Jin HWANG ; Yun Joung YANG ; Ji Hyun PARK ; Dae Yeol LEE
Journal of Korean Society of Pediatric Endocrinology 2004;9(1):59-65
PURPOSE:Ghrelin is an endogenous ligand of the growth hormone secretagogue receptor, and stomach is the major site of ghrelin secretion. The purpose of this study is to compare the serum ghrelin concentrations between patients with type 2 diabetes mellitus (DM) and normal adults. We studied also whether serum ghrelin levels in the patients with type 2 DM are correlated with body mass index (BMI), serum insulin, lipid profiles, and creatinine levels. METHODS:Forty patients with type 2 DM and forty normal adults were included in this study. We measured heights and weights of the subjects and calculated their BMIs. Blood samples were obtained to measure the ghrelin concentration and their sera were stored at -20degreeC until used. In all subjects, serum ghrelin levels were measured using the commercially available Ghrelin(human) EIA kit. RESULTS:No differences of mean values were detected between the control group and the type 2 diabetic group for age, body weight, BMI, and the levels of serum total cholesterol, triglyceride, HDL cholesterol, and creatinine. But ghrelin level of the type 2 diabetic group (71.1+/-30.5 ng/L) was significantly lower than the control group (139.7+/-36.9 ng/L). In the control group, the ghrelin level showed positive correlation with HDL cholesterol (Pearson's correlation coefficient=0.37, P<0.05). In the diabetic group, the ghrelin level showed weakly positive correlation with insulin concentration. However, there was no significant relationship between serum ghrelin and various parameters in the diabetic patients group. CONCLUSION: In this study, ghrelin concentration in type 2 diabetic patients was lower than that in the control group. In the control group, serum ghrelin concentrations were positively correlated with HDL cholesterol. In the type 2 diabetic group, there was no significant correlation between insulin and ghrelin concentrations.
Adult
;
Body Mass Index
;
Body Weight
;
Cholesterol
;
Cholesterol, HDL
;
Creatinine
;
Diabetes Mellitus
;
Diabetes Mellitus, Type 2*
;
Ghrelin*
;
Humans
;
Insulin
;
Receptors, Ghrelin
;
Stomach
;
Triglycerides
;
Weights and Measures
9.Risperidone-induced Ventricular Premature C omplexes: A Case Report.
Journal of Korean Neuropsychiatric Association 1998;37(2):400-405
Risperidone is a potent antipsychotic agent, used in the management of the manifestations of schizophrenia. And it has recently become one of the most popular antipsychotics. We experienced one case of ventricular premature complexes that occurred during the risperidone treatment in a 53-year-old female patient with schizophrenia. Abrupt aggravation of the cardiac arrhythmia and the associated symptoms suggest the possibility that the use of risperidone might have called them. Although other possibilities exist, risperidone cannot be ruled out as the cause of the patient's cardiac adverse effect.
Antipsychotic Agents
;
Arrhythmias, Cardiac
;
Female
;
Humans
;
Middle Aged
;
Risperidone
;
Schizophrenia
;
Ventricular Premature Complexes
10.Anti-fungal test of composite agastache lotion on seven pathogenic fungi and its clinical application.
Meng NA ; Lan-ying LI ; Yun-dong YANG
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(6):414-416
OBJECTIVETo study the effect of Chinese composite recipe in treating mycotic infection.
METHODSThe growth condition of 7 kinds of fungi cultured on the media containing composite agastache lotion (CAL, consisted of 5 Chinese drugs) of different concentration was observed. Result showed that CAL could inhibit 7 kinds of fungi. Based on the above anti-fungus test, 110 patients with skin tinea or genital candidiasis were treated separately with CAL, western medicine and combined (CAL and western) medicines, the therapeutic effects of the 3 groups were observed and compared.
RESULTSThe therapeutic effect in patients treated with combined medicine was significantly better than that in the other two groups (P < 0.05).
CONCLUSIONCombined use of CAL and western medicine could enhance the cure rate in treating skin tinea and genital candidiasis. Attention should be paid on studying Chinese anti-fungal agents.
Administration, Topical ; Adolescent ; Adult ; Agastache ; chemistry ; Aged ; Antifungal Agents ; pharmacology ; therapeutic use ; Candida albicans ; drug effects ; Candidiasis, Vulvovaginal ; drug therapy ; Child ; Child, Preschool ; Dermatomycoses ; drug therapy ; Drugs, Chinese Herbal ; pharmacology ; therapeutic use ; Female ; Humans ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Phytotherapy