1.The Anatomy of Pulmonary Artery Determined by Angiography in Ventricular Septal Defect and Pulmonary Atresia.
Jung Yun CHOI ; Young Hwue KIM ; Yong Soo YUN
Journal of the Korean Pediatric Society 1989;32(12):1678-1685
No abstract available.
Angiography*
;
Heart Septal Defects, Ventricular*
;
Pulmonary Artery*
;
Pulmonary Atresia*
2.Two Cases of Double-Chambered Right Ventricle by Abnomal Muscle Bundles.
Hye Young KANG ; Jung Il NOH ; Jung Yun CHOI ; Yong Soo YUN
Journal of the Korean Pediatric Society 1994;37(5):712-717
The double-chambered right ventricle is congenital or acquired cardiac anomaly, which is characterized by aberrent hypertrophied muscular bands that divide the right ventriclar cavity into two different pressure chamber. This anomaly can complicate the natural history of patient with isolated ventricular septal defect. We experienced two cases of cases of acquired DCRV, which confirmed by two separate cardiac catherterization and angiography. The purpose of this report is to show that the aberrant muscular bands may be nonobstructive in early infancy and that the obstructive effect is developed with time as the bands become progressively more hypertrophied.
Angiography
;
Heart Septal Defects, Ventricular
;
Heart Ventricles*
;
Humans
;
Natural History
3.Clinical analysis on fetal and neonatal arrhythmia.
Young Ah LEE ; Chung Il NOH ; Jung Hwan CHOI ; Jung Yun CHOI ; Yong Soo YUN ; Chong Ku YUN
Journal of the Korean Pediatric Society 1991;34(4):507-514
No abstract available.
Arrhythmias, Cardiac*
4.A Study of the cPR Training Course for Nurse Teachers and Ambulance Drivers.
Kyung Hee KANG ; young Soo HAN ; Jung Yun HWANG
Journal of the Korean Society of Emergency Medicine 1997;8(3):353-361
No abstract available.
Ambulances*
;
Cardiopulmonary Resuscitation*
5.The value of 2-D echocardiography in diagnosis of CHD.
Sang Kyung YUN ; Young Woon BAEK ; Hyun Ki JUNG
Journal of the Korean Pediatric Society 1991;34(5):662-667
No abstract available.
Diagnosis*
;
Echocardiography*
6.Clinical Value of Demonstration of Estrogen and Progesterone Receptors using Paraffin Wax Sections in Breast Carcinoma.
Hye Kyung AHN ; Yun Jung KIM ; Young Euy PARK
Korean Journal of Pathology 1996;30(2):89-93
This study aimed at assessing the usefulness of paraffin wax sections for demonstration of ER(estrogen receptor) and PR(progesterone receptor), using brief microwave processing rather than proteolytic predigestion. The receptor status of a breast cancer is often into consideration when planning treatment nowadays. As biochemical receptor assays require large amount of fresh tumor tissue and are not always available for all tumors, pathologists are now increasingly asked to provide a service for the assessment of the receptor status in tissue routine sections. Until recently, immunohistochemical demonstration of receptors was used in frozen sections. Therefore, routinely processed paraffin wax sections of 25 cases of breast carcinoma with known ER and PR concentrations, estimated by the standard DCC(dextran-coated charcoal) biochemical assay, were examined using the ABC immunoperoxidase technique. The results were assessed semiquantitably, using a five grade scoring system. Of the 25 cases examined, with DCC cutoff point being <10 fmol,71% and 75% in positivity of each ER, PR receptor is concordant. Statistic analysis demonstrates high relationship between scoring system of IH method and DCC value in ER (R=0.6061, p=0.001) and PR (R=0.5832, p=0.001). The IH method can provide easily assessed reliable positive information about ER, PR status of breast carcinoma using routinely processed paraffin wax sections.
Breast Neoplasms
7.A simple reconstructive method in vertical deficiency of the lower eyelid with the chondrocutaneous composite graft.
Byeong Yun PARK ; In Seon JUNG ; Young Ho LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(6):993-1002
No abstract available.
Eyelids*
;
Transplants*
8.HLA-DQA1, HLA-DQB1 & HLA-DRB1 Alleles Distribution in Hepatitis B Vaccine Non-responder.
Il Tae KIM ; Yun Jung CHO ; Young Tae KIM
Korean Journal of Immunology 2000;22(2):81-86
No abstract available.
Alleles*
;
Hepatitis B Vaccines*
;
Hepatitis B*
;
Hepatitis*
;
HLA-DRB1 Chains*
10.Effects of Nocodazole on Extracellular Matrix Proteins of Cancer Cell Lines.
Byung Wook JUNG ; Joo Young KIM ; Yun Chanl LEE
Korean Journal of Anatomy 1997;30(5):521-534
Nocodazole is an anticancer agent, well-known for its antimetastatic activity that acts on microtubules, microfilaments and extracellular matrix proteins. Hela, Hep G2, A549, L929, and NIH/3T3 cell lines were cultivated in alpha-MEM with 3microM or 30microM nocodazole. To investigate the mechanism of nocodazole preventing tumor cell metastasis, the influences of nocodazole on the amounts of glycoprotein, fibronectin, laminin and actin were investigated using PAS staining and PAP technique at light microscopic level. Two designed models ; coverglass and 3-day-old rat heart fragments models, were used in observing the invasiveness of cancer cells. Partitularly the three-dimensional model coculturing cell lines and heart fragment was used in evaluating the migration and/or proliferation or the invasiveness of cell around the fragment, and observed under inverted or bright field light microscope. The amount of glycoprotein of all cell-lines increased in cells of groups treated with nocedazole for 1, 2 and 3 day. The amounts of fibronectin usually increased in cells of groups treated with nocodazole for 1, 2 and 3 day. The amounts of laminin increased in cells of groups treated with nocodazole. The amounts of actin usually increased in cells of groups treated with nocodazole for 1, 2 and 3 days. With the prolonging of nocodazole-treatment time in two dimensional model using coverglass, the cells of control group except Hep G2 cells formed monolayer in cell-free zone according to migration or proliferation of many cells. But only a few cells of experimental groups migrated or proliferated into cell-free zone. In rat heart fragment model the cells of control group showed the invasiveness into the fragment but few or none of the cells from experimental groups attached around the fragment. Taken together, nocodazole increased the synthesis of fibronectin and laminin in cells in place of depolymerizing microtubules. Therefore, the amounts of extracellular matrix proteins in the extracellular space increased. And the increase amounts of actin connected to the extracellular matrix proteins through the integrin of plasma membrane seemed to strengthen cell attachment because of accordance between the orientation of actin and extracellular matrix proteins. Since it is important for cancer cells` metastasis to secrete various enzymes to pass through extracellular matrix proteins, it is expected more difficult for the cells to metastasize into other regions due to the increase of extracellular matrix proteins. As a result of confirmation of antiinvasive actions using two kinds of model, nocodazole seems to be a valuable anti-metastatic agent by supressing the cell motility and consequently, the invasiveness into the fragment. Nocodazole at concentration of 3microM will be probably anticipated antimetastatic activity reflecting that the effects of nocodazole between 3microM and 30microM groups had no differences.
Actin Cytoskeleton
;
Actins
;
Animals
;
Cell Line*
;
Cell Membrane
;
Cell Movement
;
Extracellular Matrix Proteins*
;
Extracellular Matrix*
;
Extracellular Space
;
Fibronectins
;
Glycoproteins
;
Heart
;
Hep G2 Cells
;
Laminin
;
Microtubules
;
Neoplasm Metastasis
;
Nocodazole*
;
Rats