1.The Revenue and Expenditure Accounting of Hospital Financial Project Subsidy Funds
Chinese Health Economics 2013;(9):91-92
Objective: Discuss the revenue and expenditure accounting of hospital finance project subsidy funds. Methods: The methods can be divided into direct ( authorization) payment, a ( multiple) completed fixed assets accounting processing. Results:Clearly reflect the sources and spending of hospital’s financial aid project funding. Conclusion:An all-round finance process of hospital assets of project funding is presented to meet the budget funds management and the needs of hospital accounting.
2.Variability of Pyramidal Neurons in Hippocampal CA1 Area with Time after Heat Stroke in Rats
Mingsheng WAN ; Yun ZHANG ; Shiwen WU
Chinese Journal of Rehabilitation Theory and Practice 2016;22(7):793-796
Objective To observe the pyramidal neurons in the hippocampal CA1 area varying with time after heat stroke in rats. Meth-ods Sprague-Dawley rats were divided into sham group (n=5) and heat stroke group (n=14), and the heat stroke group was divided into 7-day subgroup and 21-day subgroup (n=7 at each group) after heat stroke. Heat stroke group was established model of heat stroke. The brain tissues of rats were observed with Nissl staining to count the living pyramidal neurons in hippocampal CA1 area. Results The number of living pyramidal neurons in hippocampal CA1 area decreased in the heat stroke group (F=11.80, P<0.01), and decreased more in the 21-day subgroup than in the 7-day subgroup (P<0.05). Conclusion Pyramidal neurons in hippocampal CA1 area decrease with time after heat stroke, which may be associated with the learning and memory impairment.
3.Clinical Observation of Ambroxol Hydrochloride in the Adjuvant Treatment of Elderly Patients with Chronic Obstructive Pulmonary Disease
Hong LIU ; Yun WAN ; Hongju ZHONG
China Pharmacy 2016;27(15):2048-2050
OBJECTIVE:To observe the clinical efficacy and safety of ambroxol hydrochloride in the adjuvant treatment of el-derly patients with chronic obstructive pulmonary disease. METHODS:94 elderly patients with chronic obstructive pulmonary dis-ease were randomly divided into control group(48 cases)and observation group(46 cases). Control group was given oxygen inha-lation,antispasmodic asthma,expectorant and antitussive,antibiotics against infections,bronchodilation drugs,glucocorticoids and other conventional treatment;observation group was additionally given 30 mg Ambroxol hydrochloride injection,adding into 200 ml 5% glucose injection by intravenous infusion,twice a day. The treatment course for both groups was 2 weeks. The clinical efficacy,improvement of cough and sputum volume before and after treatment in 2 groups were observed,and incidence of ad-verse reactions was recorded. RESULTS:The clinical efficacy in observation group was significantly higher than control group,re-ducing degree of cough and sputum volume were significantly superior to control group,the differences were statistically significant (P<0.05);and there were no significant differences in the incidence of total adverse reactions,nausea,stomach heartburn,rash and indigestion between 2 groups(P>0.05). CONCLUSIONS:Based on the conventional treatment,ambroxol hydrochloride can effectively relieve symptoms and improve efficacy in the adjuvant treatment of elderly patients with chronic obstructive pulmonary disease,with no obvious adverse reactions and reliable safety.
4.Reaction between antineoplastic nitidine chloride and sodium hydroxide solution
Hongqin YANG ; Weiqin WAN ; Yun ZHOU ;
Academic Journal of Second Military Medical University 2000;0(08):-
Objective: To challenge the previously proposed anticancer mechanism of nitidine chloride, which suggest there exist anti tumor C(6)=N(5) double bond structure. Methods: An antitumor alkaloid, nitidine chloride, was treated in aqueous sodium hydroxide solution without the presence of certain kinds of amino acids and oxygen. Results and Conclusion: It had been revealed that virtually equal amount of 5, 6 dihydronitidine and oxynitidine was produced under such circumstances. The results suggest the anticancer mechanism of nitidine chloride need further investigation. [
5.Plasma Levels of Dehydroepiandrosterone Sulfate ( DHEA - S ) and Total Testosterone in the Patients with Female androgenetic Alopecia.
Seok Kweon YUN ; Hong Yong KIM ; Chull Wan IHM
Korean Journal of Dermatology 1995;33(6):1060-1065
BACKGROUND: It has been known that androgenetic alopecia in both male and female is due to the role of the androgen hormone in the hair follicle, but the level of the androgen hormone in the plasma is controversial in relation with the development of the alopecia. OBJECTIVE: We have tried the clarify if there is any or no difference in the plasma levels of the hormones between the normal female and the patient with alopecia, because the range of the plasma DHEA-S and total testosterone in the normal female is very wide. METHODS: Plasma levels if the hormones were examined in 22 patients with female androgenetic alopecia and 20 normal females. RESULTS: 1. In DHEA-S, 21(95.5%) aut of 22 female androgenetic alopecia patients were in the normal range while 20(100%) of the 20 normal females were all within the normal range. However the mean value of the hormone(88.89+101.41 g/dl) in the patient group was significantly higher than that(82.18+44.03 g/dl) of the normal group(p<0.05). 2. In total testosterone, 17(94.4%) out of the 18 patents were in the normal range while 20 (100%) of 20 normal females were all within the normal range. However the mean value of the hormone(0.22+0.20ng/ml) in the patient group was significantly higher than that(0.08+0.09ng/ml) of the normal group(p<0.05). 3. As for distribution of DIEA S according to the age, the value of the patient group was higher than that of the normal group in all age groups studied. In the distribution of total testosterone according to age, there was no difference between the normal and the patient in the twenties. After the twenties, the testosterone levels were higher in the patients than the normal females. CONCLUSION: There were significant differences in mean values of plasma DHEA-S and total testosterone between the patients and the normal females although individuals in both groups were largely wit,hin normal range of the hormones.
Alopecia*
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Dehydroepiandrosterone Sulfate*
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Dehydroepiandrosterone*
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Female*
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Hair Follicle
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Humans
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Male
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Plasma*
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Reference Values
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Testosterone*
6.Detection of Hepatitis C Virus by RIA, Recombinant Immunoblot Assay and Nested RT-PCR.
Jae Soo KIM ; Jong Wan KIM ; Yun Tai LEE
Journal of the Korean Society of Virology 2000;30(2):151-159
No Abstract Available.
Hepacivirus*
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Hepatitis C*
;
Hepatitis*
7.A Case of Multiple Tubular Apocrine Adenoma.
Min Young YOU ; Seok Kweon YUN ; Chull Wan IHM
Korean Journal of Dermatology 2000;38(5):659-663
No Abstract Available.
Adenoma*
8.Exploration and Comparative Study on Mammography and MRI in Diagnosis of Breast Lesions after Breast Augmentation with PAG Injection
Yun WAN ; Yumei YOU ; Yuhui HUANG ; Weikang HUANG
Journal of Practical Radiology 1992;0(11):-
Objective To explore the value of mammography and MRI in the diagnosis of the breast lesions after breast augmentation with polyacrylamide gel(PAG) injection.Methods The mammographic and MRI findings of 26 patients with PAG augmentation mammoplasty retrospectively.Results The location and the form of PAG after augmentation mammoplasty could be detected by both mammography and MRI.The lesions in 4 cases with complications were detected by MRI but mammography.Conclusion MRI plays the more important role than mammography in the diagnosis of the complications or associated with breast lesions after augmentation mammoplasty with PAG.
9.The Treatment of de Qurvain's Disease
Duck Yun CHO ; Young Gil HAHM ; Chang Wan SEON
The Journal of the Korean Orthopaedic Association 1996;31(5):1099-1104
We treated the 90 wrists (83 patients) with de Quervain's disease, and studied retrospectively the factors affecting the result of treatment, and the results of several treatment modalities, compared with published series of this disease. There was significant association between outcome and duration of symptoms before treatment, but age, sex, associated disease, and hand dominance were not associated(chi-square test, p < 0.05). And 75 wrists received single injections of steroid and local anesthetic into the tendon sheaths with complete pain relief in 59 wrists (69%). Furthermore, an additional injection gave pain abatement in 6 wrists. And regardless of treatment method, 95% of the whole patients had satisfactory outcome at a mean of 54 months (minimum follow-up, 45 months). We concluded that injection of steroid is the preferred initial treatment in de Quervain's disease, giving complete and lasting relief in 87% of cases.
De Quervain Disease
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Follow-Up Studies
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Hand
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Humans
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Methods
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Retrospective Studies
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Tendons
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Wrist
10.Anti-liver fibrosis activities of the extracellular domain of transforming growth factor beta type II receptor fusion protein in vivo
Yanfei CAI ; Aini WAN ; Yun CHEN ; Jian JIN
Journal of China Pharmaceutical University 2019;50(2):246-252
This study is performed to analyze the anti-liver fibrosis effect of the fusion protein of human serum albumin and extracellular domain of transforming growth factor beta type II receptor(eTGFBR2)in vivo to looking for the more stable anti-liver fibrosis drug. The mice model of liver fibrosis was constructed by CCl4 induction and the following groups are included in the study: the control group, CCl4 model group, the positive control group, eTGFBR2 treatment group, HSA-eTGFBR2 treatment group, and HSA group. Hematoxylin eosin staining, serum liver function index detection, and western blot are used to identify the anti-liver fibrosis activities. The results showed that: (1)CCl4 caused liver structure disorder, hepatocellular necrosis, collagen fibers proliferation, and induced liver fibrosis at last; (2)HSA-eTGFBR2 and its monomer drug improved the symptoms of liver fibrosis significantly, as well as reduced the damage of liver cells and collagen deposition, and recovered the liver basic structure to normal. Both of HSA-eTGFBR2 and its monomer drug improved liver function and reduced the expression level of liver fibrosis marker α-SMA and COL I. Moreover, the anti-liver fibrosis effect of the fusion protein is comparable to the monomer drug. In contrast, the albumin had no effect on therapeutic effect; (3)Reducing the injection frequency of HSA-eTGFBR2 achieved the comparable effects to the monomer drug with the normal injection frequency. In summary, the fusion protein HSA-eTGFBR2 has good anti-liver fibrosis effect. In addition, reducing the injection frequency of the fusion protein could also achieve the comparable treatment with the monomer drug, indicating that the fusion protein is stable and has longer half-lives and then a relatively positive application prospect in future.