1.Surgical Treatment of Traumatic Rib Fracture with Judet's Rib Struts.
Gang Bae HUH ; Dae Yun KIM ; Sung Rae CHO
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(10):1010-1014
Judet's rib struts which are designed for osteosynthesis are made of stainless steel. This report describes clinical analysis of our experiences of 30 cases with the operative stabilization of multiple rib fractures with Judet's rib struts from December, 1995, to December, 1996 in Chungmoo Hospital, Chounan. Our indications for operative stabilization were as follows: 14 cases in flail chest, 8 cases in severe displacement of rib including segmental fractures, 7 cases in additional procedures during intrathoracic operation, and 1 case in other cause. Postoperative artificial ventilation is needed in only 1 case for 5 days and posto- perative complications were few: 2 cases of hemopneumothorax, 2 cases of alcohol with- drawal delirium, and 1 case of postoperative hepatitis. Average duration of hospital admission who have limited thoracic injuries was 10.5 days. Though more comparative studies is necessary, we find this technique to be better than previously published methods, since it provides better stabilization and immobilization of the ribs and shortening the duration of hospital admission.
Delirium
;
Flail Chest
;
Hemopneumothorax
;
Hepatitis
;
Immobilization
;
Rib Fractures*
;
Ribs*
;
Stainless Steel
;
Thoracic Injuries
;
Ventilation
2.Immunohistochemical study of the endocrine cells in the gastrointestinal tract of the Korean native goat.
Sung Whan CHO ; Moo Kang KIM ; Si Yun RYU ; Min Do HUH
Korean Journal of Anatomy 1992;25(1):71-81
No abstract available.
Endocrine Cells*
;
Gastrointestinal Tract*
;
Goats*
3.Correlation between Clinical Outcome and Proliferation Index in Diffuse Large B-Cell Lymphoma.
Sung Shin PARK ; Joo ryung HUH ; Seung Sook LEE ; Yun Koo KANG ; Dae Seog HEO ; Chul Woo KIM
Korean Journal of Pathology 1999;33(7):475-482
The diffuse large B-cell lymphoma category of the Revised European American Classification of Lymphoid Neoplasms (REAL) encompasses different morphologic lymphoma subtypes in a single entity, especially the diffuse large cell (DLC) and the immunoblastic (IBL) subtypes by Working Formulation (WF). The aim of this study is to determine the influence of the morphologic subdivision within this category with respect to clinical outcome and proliferative index using Ki-67 immunostainig combined with image analysis. We retrospectively reviewed 74 patients from 1990 to 1996, who were diagnosed with diffuse large B-cell lymphoma. All cases were reclassified according to REAL and Working Formulation (WF), and Ki-67 immunostaining was performed in all the cases. Fifty-eight cases (78.4%) were classified as DLC and 16 cases (21.6%) as IBL, according to WF. Twenty one cases (28.4%) showed nodal involvement and 53 cases (71.6%), extranodal involvement. All cases were found to display a variable degree of nuclear Ki-67 staining. A proliferative index of 50% or higher identified a group of patients (77%) who had poor clinical results. Overall survival was significantly reduced in these patients displaying high Ki-67 associated proliferative index compared to those with a low proliferative index (p=0.007). 5-year survival estimates were 93% in the low proliferative index group and 55% in the high proliferative index group. A multivariate regression analysis incorporating commonly used clinical prognostic factors confirmed the independent effect of proliferation index on survival. Moreover, all of the 16 IBL cases showed Ki-67 positivity of 50% or higher, which correlates with the poor clinical outcome compared to 70.7% of DLC (p=0.014). We conclude that subdivision of the diffuse large B-cell lymphoma category of the REAL classification is necessary in terms of prognostic significance in correlation with Ki-67 proliferative index.
B-Lymphocytes*
;
Classification
;
Humans
;
Lymphoma
;
Lymphoma, B-Cell*
;
Lymphoma, Large B-Cell, Diffuse
;
Retrospective Studies
4.Three Cases of True Splenic Cyst.
Young Soo HUH ; Su Hwan KANG ; Sung Su YUN
Journal of the Korean Association of Pediatric Surgeons 1999;5(2):130-136
Cysts of the spleen are uncommon disease entities and can be classified as either primary (true) or secondary (pseudo-) depending on the presence of a true epithelial lining. True nonparasitic cysts of spleen are very rare, and the majority of the cases are classified as epidermoid cysts. True splenic cysts were found in three children during the last eleven years (1989~1999) in Yeungnam University Hospital. Two of the children were girls and one was boy. The age at diagnosis ranged from 7 to 15 years. Abdominal ultrasonography was utilized to the initial diagnosis, and computerized tomography was done for the detailed studies. Radionuclide scanning was performed in a patient. Surgical resection (one partial splenectomy and two total splenectomies) was performed. The cysts were from 4cm to 9cm in maximum diameter. Pathologic finding was epidermoid cyst of the spleen.
Child
;
Diagnosis
;
Epidermal Cyst
;
Female
;
Humans
;
Male
;
Spleen
;
Splenectomy
;
Ultrasonography
5.Evisceration for Intractable Endogenous Endophthalmitis.
Yun Sung HUH ; Hwa Sun CHUNG ; Jun Hyuck SON
Journal of the Korean Ophthalmological Society 2008;49(3):396-400
PURPOSE: To evaluate the clinical aspects of severe endogenous endophthalmitis requiring evisceration,particularly underlying disease, causative microorganisms, and infection focus, and to assess the outcome of evisceration. METHODS: The records of 13 patients who were diagnosed with endogenous endophthalmitis requiring evisceration and treated at Yeungnam University Hospital from July 1994 to April 2007 were retrospectively reviewed. RESULTS: Of the 13 patients, all patients had diabetes mellitus, five had advanced liver disease, and one had aplastic anemia. Infection foci were pyelonephritis, pneumonia, and liver abscess. Five cases were confirmed with positive culture of lebsiella pneumoniae. Ten cases underwent evisceration with hydroxyapatite implantation, and three cases were treated conservatively because the patient was in poor systemic condition. Of the 10 patients who underwent evisceration, ocular implants were exposed in five cases. CONCLUSIONS: This study suggests that evisceration with primary orbital implant insertion for endogenous endophthalmitis involves the risk of implant exposure, but after secondary repair, all patients have stable clinical courses.
Anemia, Aplastic
;
Diabetes Mellitus
;
Durapatite
;
Endophthalmitis
;
Humans
;
Liver Abscess
;
Liver Diseases
;
Orbital Implants
;
Pneumonia
;
Pyelonephritis
;
Retrospective Studies
6.Surgical Outcomes of Intermittent Exotropia as a Function of Strabismic Angle.
Jun Hyuk SON ; Yun Sung HUH ; Myung Mi KIM
Korean Journal of Ophthalmology 2006;20(4):230-233
PURPOSE: To analyze postoperative results of intermittent exotropia as a function of the difference in strabismic angles measured immediately and another time prior to the surgery. METHODS: We reviewed the clinical records of intermittent exotropia patients who received surgery and had differences greater than or equal to 10 prism diopters (PD) between the last preoperative measurement of strabismic angle and another previous measurement. After applying various exclusion criteria, 66 patients were entered into our study. At the last follow-up visit after surgery, we divided postoperative results into 3 categories: (1) poor; with greater than 10 PD of esotropia or angle of exodeviation of 20 PD or more (2) moderate; with 6-10 PD of esophoria/tropia or 10-19 PD exodeviation, or (3) good; with 1-5 PD of esophoria/tropia or an angle of exodeviation less than 10 PD, or orthophoria. RESULTS: Good results were higher in patients where the difference in strabismic angle was 10 PD or greater between the last measurement and any other earlier measurement. CONCLUSIONS: In cases of Intermittent exotropia where the last preoperative value of strabismic angle was greater than any previous preoperative measurement, surgical dosage based on the last preoperative measurement yielded better results.
Treatment Outcome
;
Severity of Illness Index
;
Retrospective Studies
;
Ophthalmologic Surgical Procedures/*methods
;
Oculomotor Muscles/*physiopathology/surgery
;
Male
;
Infant
;
Humans
;
Follow-Up Studies
;
Female
;
Eye Movements/*physiology
;
Exotropia/physiopathology/*surgery
;
Child, Preschool
7.Atypical pulmonary artery sling with diffuse-type pulmonary arteriovenous fistula.
June HUH ; Jung Yun CHOI ; Youn Woo KIM ; Chung Il NOH ; Yong Soo YUN ; Chang Sung SON ; Young Chang TOCKGO
Journal of Korean Medical Science 1999;14(1):80-84
The case of a cyanotic infant with a rare combination of atypical pulmonary artery sling, imperforate anus, absence of the left kidney, interruption of the inferior vena cava, left side hemihypertrophy and diffuse-type pulmonary arteriovenous fistula is described. The clinical features were confusing, because of compounding abnormalities involving the respiratory tract and pulmonary circulation. The diagnostic approach to the etiology of cyanosis is discussed and the embryonic origin of pulmonary artery sling is reviewed.
Arteriovenous Fistula/ultrasonography
;
Arteriovenous Fistula/pathology*
;
Case Report
;
Human
;
Infant
;
Male
;
Pulmonary Artery/pathology*
8.Clinical Experience of Transcatheter Coil Embolization in Children.
Jeong Jin YU ; Jae Young LEE ; Eun Jung CHEON ; June HUH ; Youn Woo KIM ; Ho Sung KIM ; Chung Il NOH ; Jung Yun CHOI ; Yong Soo YUN
Korean Circulation Journal 1998;28(5):691-699
BACKGROUND: Transcatheter coil embolization has been described as a method of nonsurgical closure of variable pathologic vascular structures. This study was aimed to evaluate the outcome of transcatheter coil embolization in variable clinical conditions. METHODS AND RESULTS: We collected data from patients' medical record and their cardiac angiography films. From January 1995 to June 1997, coil embolization was attempted in 51 patients who were 38 patients with systemic-pulmonary collaterals (5 patients have venous collaterals, too), six patients with venous collaterals, nine patients with patent ductus arteriosus (PDA), one patient with Blalok-Taussig shunt (BT shunt), one patient with coronary-right atrial fistula and one patient with coronary-right ventricular fistula. In 38 patients with systemic-pulmonary collaterals, 123 coils were inserted to 70 collaterals, therefore mean 1.79+/-0.77 coils were inserted to one collateral. The results were complete occlusions (74%), incomplete occlusions (21%), and partial occlusions (4%). In six patients with venous collaterals, the outcomes were complete occlusions (50%) and incomplete occlusions (50%). In a patient with BT shunt, hemolytic anemia occurred in 1st attempt and in 2nd attempt, shunt was incompletely occluded and one coil was carried away and embolized the peripheral pulmonary artery. In nine patients with PDA, ten cases of transcatheter coil embolization was executed. Mean minimum ductal diameter was 2.1+/-0.85 mm. The results were initial occlusion (30%), occlusion within one month (66%), and occlusion within one year (75%). Left pulmonary artery stenosis owing to coil insertion was not found. In one case of coil malposition, retrieval and reinsertion of coil was successful. In two patients who have coronary artery fistula, coil embolization was successfully executed without any complications. CONCLUSIONS: Transcatheter coil embolization executed in variable clinical conditions without significant complications. It was effective and safe nonsurgical method.
Anemia, Hemolytic
;
Angiography
;
Child*
;
Constriction, Pathologic
;
Coronary Vessels
;
Ductus Arteriosus, Patent
;
Embolization, Therapeutic*
;
Fistula
;
Humans
;
Medical Records
;
Pulmonary Artery
9.Clinical Experience of Transcatheter Coil Embolization in Children.
Jeong Jin YU ; Jae Young LEE ; Eun Jung CHEON ; June HUH ; Youn Woo KIM ; Ho Sung KIM ; Chung Il NOH ; Jung Yun CHOI ; Yong Soo YUN
Korean Circulation Journal 1998;28(5):691-699
BACKGROUND: Transcatheter coil embolization has been described as a method of nonsurgical closure of variable pathologic vascular structures. This study was aimed to evaluate the outcome of transcatheter coil embolization in variable clinical conditions. METHODS AND RESULTS: We collected data from patients' medical record and their cardiac angiography films. From January 1995 to June 1997, coil embolization was attempted in 51 patients who were 38 patients with systemic-pulmonary collaterals (5 patients have venous collaterals, too), six patients with venous collaterals, nine patients with patent ductus arteriosus (PDA), one patient with Blalok-Taussig shunt (BT shunt), one patient with coronary-right atrial fistula and one patient with coronary-right ventricular fistula. In 38 patients with systemic-pulmonary collaterals, 123 coils were inserted to 70 collaterals, therefore mean 1.79+/-0.77 coils were inserted to one collateral. The results were complete occlusions (74%), incomplete occlusions (21%), and partial occlusions (4%). In six patients with venous collaterals, the outcomes were complete occlusions (50%) and incomplete occlusions (50%). In a patient with BT shunt, hemolytic anemia occurred in 1st attempt and in 2nd attempt, shunt was incompletely occluded and one coil was carried away and embolized the peripheral pulmonary artery. In nine patients with PDA, ten cases of transcatheter coil embolization was executed. Mean minimum ductal diameter was 2.1+/-0.85 mm. The results were initial occlusion (30%), occlusion within one month (66%), and occlusion within one year (75%). Left pulmonary artery stenosis owing to coil insertion was not found. In one case of coil malposition, retrieval and reinsertion of coil was successful. In two patients who have coronary artery fistula, coil embolization was successfully executed without any complications. CONCLUSIONS: Transcatheter coil embolization executed in variable clinical conditions without significant complications. It was effective and safe nonsurgical method.
Anemia, Hemolytic
;
Angiography
;
Child*
;
Constriction, Pathologic
;
Coronary Vessels
;
Ductus Arteriosus, Patent
;
Embolization, Therapeutic*
;
Fistula
;
Humans
;
Medical Records
;
Pulmonary Artery
10.Rapid Expansion and Auto-Grafting Efficiency of Porcine Full Skin Expanded by a Skin Bioreactor Ex Vivo.
Man Il HUH ; Sun Hee AN ; Hwi Gang KIM ; Yun Jeong SONG ; Eun Chang CHOI ; Sang Hyun AN ; Woo Sung CHOI ; Jeung Soo HUH ; Jeong Ok LIM
Tissue Engineering and Regenerative Medicine 2016;13(1):31-38
Full skin auto-grafts are required for reconstruction of skin burns and trauma scars. However, currently available clinical approaches such as sheet skin graft, mesh skin grafts, artificial skin graft, and in vivo skin expansion have limitations due to their potential danger for secondary damage and scar formation at the donor site, and discomfort during skin expansion. We developed an advanced bioreactor system and evaluated its function in skin expansion using porcine full skin. The reactor was designed as a pneumatic cylinder type, was programmed to adjust the pressure and the operating time. The system was composed of culture chamber unit, environmental control unit, and monitoring unit. Skins were expanded at 200 kPa pneumatic force and the expanded skins were analyzed by immunohistochemistry and histology. Furthermore we carried out auto-grafting experiment of the expanded skins in vivo using Yucatan pigs and skins were harvested and histologically analyzed after 8 weeks. The results showed that the bioreactor expanded skins to 160% in 4 hours. Histological analysis of the expanded skins revealed that epidermal cells and dermal fibroblasts were viable and remained integrity. The results of auto-grafting experiment indicated that fibrosis and scars were not detected in the grafted skins. This study demonstrates that the newly developed skin bioreactor enabled to obtain large sized full skin rapidly and successful grating.
Bioreactors*
;
Burns
;
Cicatrix
;
Fibroblasts
;
Fibrosis
;
Humans
;
Immunohistochemistry
;
Skin*
;
Skin, Artificial
;
Swine
;
Tissue Donors
;
Transplants