1.Experimental Study on Tissue Mast Cell Change of Ratskin Elicited by Mechanical Irritation Under General and Local Ansthesia.
Korean Journal of Dermatology 1972;10(1):11-22
Normal albino rats weighing 180-200 gm were used for a series of this investigation on change of skin mast cell under general and local anesthesia. At first, left side abdominal skin was prepared by hair cutting with scissors about 3cm square and eight irritations by mean of biting with tip of forceps mosquito were applied along the prepared skin margin. Skin specimens were submitted from central area which surrounded by irritated points and also from intact contra-lateral area in 15, 30, 60 and l20 minutes invervals. Submiitted skin specimens were fixed in 10% formalin solution, then were stained with 1% toluidine blue. The number of mast cell was counted under 450X of microscopic examination. CONCLUSION l. There were two stages in changes of skin tissue mast cell number on normal saline solution injected area and irritated area by mean of biting with tip of forceps without any types of anesthesia. i) Decreasing stage: Number of skin tissue mast cell was decreascd and reached to the lowest level at 30 minutes after each irritation. ii) Increasing stage: Number of skin tissue mast cell was increased to the highest level at 120 minutes after each irritation. 2. General ether anesthesia could not infIuence on the change of mast cell number after mechanical biting irritation. 3, Local anesthesia with 2% procaine hydrochloride solution revealed slightly suppressing effect to increasing number of mast cell at 60 and 120 minutes after mechanical irritation. Hnwever, it was not evidence at 15 and 30 minutes after mechanical irritation. 4. There was no significant change of rnast cell number in the intact contralateraI skin area within 120 minutes under gencral and local anesthesia. 5. The number of degranulated mast cells did not correlated with counted total number of mast cells.
Anesthesia
;
Anesthesia, Local
;
Animals
;
Cell Count
;
Culicidae
;
Ether
;
Formaldehyde
;
Hair
;
Mast Cells*
;
Procaine
;
Rats
;
Skin
;
Sodium Chloride
;
Surgical Instruments
;
Tolonium Chloride
2.131I-MIBG scintigraphy in the evaluation of suspected pheochromocy-toma.
Sei Jung OH ; Hyung Sik YOO ; Chang Yun PARK ; So Jin LEE
Korean Journal of Nuclear Medicine 1992;26(2):365-370
No abstract available.
Radionuclide Imaging*
3.Ultrasonographic pseudokidney sign in gastrointestinal diseases
Jong Doo LEE ; Jeong Hee PARK ; Hyung Sik YOO ; Ki Whang KIM ; Chang Yun PARK
Journal of the Korean Radiological Society 1982;18(2):333-339
A characteristic sonographic pattern that suggest a bowel lesion, called "Pseudokidney Sign" because itresembles the ultrasonic appearance of the kidney
Barium
;
Gastrointestinal Diseases
;
Kidney
;
Mucous Membrane
;
Mucus
;
Neoplasm Metastasis
;
Ultrasonics
;
Ultrasonography
4.Radiological aspect of pancreatic pseudocysts
Tae Sub CHUNG ; Sue Jin LIM ; Hyung Sik YOO ; Jung Ho SUH ; Chang Yun PARK
Journal of the Korean Radiological Society 1982;18(2):306-315
Pancreatic pseudocyst occurs as a complication of pancreatitis or trauma, which results in the escape of pancreatic enzymes from the parenchyma or ductal system of pancreas. At that time, serum amylase may have returned to normal level, and the patient may be subjectively asymptomatic. In this phase, the radiologic findings are relatively greater significance than laboratory data. In the conventional radiologic study, pancreatic pseudocyst have been frequently confused with other retroperitoneal mass, but recently with clinical application of ultrasound and CT scan, more accurate diagnosis can be obtained. The brief results are as follows; 1. Male to female ratio was 3:2 in 15 patients. Incidence was most common in young adult age. Most frequent symptom was epigastic pain, and which was noted in 11 cases of patients. 7 cases of patients had past history of abdominal trauma and past history of pancreatitis was only in 1 case. Most common laboratory finding was leukocytosis in 8cases of patients and elevated serum amylase was also noted in 7 cases. 2. In each 5 cases of patients, plain chest roentgenologic evidence of left side pleural effusion and hemidiaphragm elevation were observed. 3. On flat abdomen film, soft mass shadow was visualized in 8 cases of patients. On UGI series, evidence of retrogastric space widening was observed in 11 cases of patients. 4. The location of pseudocyst is mainly in body and tail of pancrease in 11 cases of patients. 5. More accruable diagnosis can be obtained through application of ultrasound and CT scan.
Abdomen
;
Amylases
;
Diagnosis
;
Female
;
Humans
;
Incidence
;
Leukocytosis
;
Male
;
Pancreas
;
Pancreatic Pseudocyst
;
Pancreatitis
;
Pancrelipase
;
Pleural Effusion
;
Tail
;
Thorax
;
Tomography, X-Ray Computed
;
Ultrasonography
;
United Nations
;
Young Adult
5.Ultrasonographic findings of pelvic masses
Youn Jin KIM ; In Soo HONG ; Hyung Sik YOO ; Chang Yun PARK
Journal of the Korean Radiological Society 1982;18(3):610-617
Ultrasonography affords an accurate assessment of the presence, size, location and internal consistency of apelvic mass. We present our experience of 105 cases of pelvic masses in female patients by ultrasonography, andthe results are as described; 1. Ultrasonography is nonspecific, however, the possibility of mucinous cystadenomaof ovary, teratoma(dermoid cyst), uterine leiomyoma and trophoblastic disease can be suggested due to theircharacteristic internal consistency. 2. This smooth internal septation seen within mucinous cystadenoma, eccentricsolidmural component of dermoid cyst, enlarged uterine wall with lobulated outer margin of leiomyoma, andyesicular appearance of trophoblastic disease were the specific sonographic features. 3. Loculated ascites and hydronephrosis were identified with malignant ovarian neoplasm and pelvic metastasis. 4. Accurate ultrasonographicdiagnosis was made in 88 cases (83.7%) and it may be improved with clinical history of the mass in question.
Ascites
;
Cystadenoma, Mucinous
;
Dermoid Cyst
;
Female
;
Humans
;
Hydronephrosis
;
Leiomyoma
;
Mucins
;
Neoplasm Metastasis
;
Ovarian Neoplasms
;
Ovary
;
Trophoblasts
;
Ultrasonography
6.Evaluation of radionuclide testicular scan
Nam Yoon HUH ; Youn Jin KIM ; Hyung Sik YOO ; Chang Yun PARK
Journal of the Korean Radiological Society 1983;19(2):441-448
There has been no adequate diagnostic method for the diagnosis of intrascrotal lesions until recent days. Butafter the development of radionuclide testicular scan, early and relatively accurate diagnosis of the testicularlesions are possible. So the authors analyzed the 32 cases of patients who were examined by testicular scan andconfirmed by follow up study or operation, and the results are as follows; 1. These 32 cases consists of 13 casesod epididymitis, 7 cases of testicular torsion, 4 of cryptorchism, 2 of testicular tumor and etc. The over alldiagnostic accuracy is about 69%. 2. In epididymitis, the diagnostic accuracy is 85%(11/13) and the findings ofscan are increased perfusion in radionuclide angiogram and hot activity noted mainly in peripheral portion of thetesticle in static image. 3. In cases o testicular torsion, diagnostic accuracy is 86%(6/7). Acute torsion showsnormal perfusion in angiogram and round cold area instatic image. But in missed torsion, perfusion is increasedand round cold area wit surrounding hyperemia is noted in static image. Radionuclide testicular scan seems to benoninvasive, inexpensive, easily available and simple to perform with low gonadal radiation dose. So it can bevery useful as the first study in patients with acute testicular symptoms.
Cryptorchidism
;
Diagnosis
;
Epididymitis
;
Follow-Up Studies
;
Gonads
;
Humans
;
Hyperemia
;
Male
;
Methods
;
Perfusion
;
Spermatic Cord Torsion
7.Transcatheter hepatic artery embolization of liver cancer
Jong Tae LEE ; Hyung Sik YOO ; Jung Ho SUH ; Heun Yung YUN
Journal of the Korean Radiological Society 1985;21(6):849-857
From March 1985 to Sep.1985, Transcatheter hepatic arterial embolization was perfromed in 17 primary heptomaand 8 metstasis of liver in Department of Radiology, Yonsei University College of Medicine. Metastatic cancers ofliver were one nasopharyngeal cancer, one small bowel leiomyosarcoma, one gall bladder cancer and 5 colon cancers.The used embolization materials were the followings: Gelfoam particles for one primary hepatoma, 95% absoluteethanol for 4 patients, Ivalon(250-590micro m) for 19 patients and autologous blood clots for one metastasis, Theresults were summarized as the follows: 1. The devascularization of tumor vessels in post-emblization hepaticangiogram was complete in 6 primary hepatom and one metastasis and partial in 11 primary hepatoma and 7metastasis. 2. In the follow-up CT evaluation 3 to 4 weeks after embolization, well necrotic density was revealedin 8 primary hepatoma and one metastasis. 3. The complications were fever with higher than 38 degrees C(92%),abdominal pain (72%) and nausia or vomiting(40%). They were subsided wtihin one to 7 days after embolization. 4.In liver function study, sGOT and sGPT were elevated in 80% of total cases and returned to normal within 15 to 30days. LDH was variable. In 4 cases of absolute ethanol infusion, above liver enzymes were markedly elvated as 10times or more as normal range.
Alanine Transaminase
;
Aspartate Aminotransferases
;
Carcinoma, Hepatocellular
;
Colon
;
Ethanol
;
Fever
;
Follow-Up Studies
;
Gallbladder Neoplasms
;
Gelatin Sponge, Absorbable
;
Hepatic Artery
;
Humans
;
Leiomyosarcoma
;
Liver Neoplasms
;
Liver
;
Nasopharyngeal Neoplasms
;
Neoplasm Metastasis
;
Reference Values
8.Evaluation of abdominal trauma by computed tomography and ultrasonography
Do Yun LEE ; Sang Jin KIM ; Jong Tae LEE ; Hyung Sik YOO
Journal of the Korean Radiological Society 1986;22(3):392-397
Out of 75 patients who were admitted to our hospital because of abdominal trauma and were undergone theprocedures such as ultrasonography and/or CT scan within 24 hours of abdominal trauma due to suspected abdominalorgan injury. We analyzed the results of 38 patients who were confiremd of diagnosis by operation, follow-up CTscan or ultrasonography. 1. In the abdominal organ injury, solid organ injury consists of 8 cases of spleenlaceration, 1 of splenic subcapsular hematoma, 7 of hepatic laceration, 7 of pancreas laceration, 3 of renallaceration, and 3 of subcapsular hematoma of kidney. 2. In addition, there were 7 bowel and/or mesentericlaceration, 2 diaphragmatic hernia, and 1 urethral rupture. 3. 2 cases fo retroperitoneal hematoma and 1 case inwhich hemoperitoneum occurred without abdominal organ injury were confirmed by follow-up CT or ultrasonography. 4.In all of the 4 patients with multiple organ injury, pancreatic laceration was associated. 5. In abdominal traumapatients, ultrasonography or CT can be used to survey rapidly the entire abdomen for possible associated injury,and be of great help to clinicians in identifying the patients who need immediate surgery or in minimizing theincidence of unnecessary emergency abdominal exploration.
Abdomen
;
Diagnosis
;
Emergencies
;
Follow-Up Studies
;
Hematoma
;
Hemoperitoneum
;
Hernia, Diaphragmatic
;
Humans
;
Kidney
;
Lacerations
;
Pancreas
;
Rupture
;
Tomography, X-Ray Computed
;
Ultrasonography
9.The influence of dentin desensitizer to shear bond strength of dental cements.
Yun Ho NA ; Nam Sik OH ; Jae Heung YOO
The Journal of Korean Academy of Prosthodontics 2007;45(5):579-588
STATEMENT OF PROBLEM: A tenderness of the dentin after tapering of teeth for dental prosthesis is a common phenomenon. In practice, the alternative desensitizer may be used for minor pain after tapering of teeth. PURPOSE: In this study, the desensitizers were used to investigate the affect decreasing of shear bond strength according to the use of various cement, such as resin, Glass Ionomer, and phosphate cement. MATERIAL AND METHOD: Three different desensitizers were used on this study. Compositions of two dentin desensitizers were HEMA(hydroxyethylmethacrylate) and glutaraldehyde. The other one is oxalic acid. Three dentin desensitizers applied on 12 degrees taper teeth. Then, Ni-Cr crowns were bonded with Resin cement, Zinc Phosphate (ZPC) cement and Glass Ionomer (GIC) cement. 120 human premolar teeth were used for specimens. The specimens were divided into four group as the reference and the empirical each with thirty specimens, then further divided into 12 group according to type of desensitizers and cement types. The shear bond strength were measured by Instron multi task instrument. RESULTS: According to the result, the measured shear bond strength in order from the weakest to the strongest in general was ZPC, Resin, and GIC. And it is found that the application of desensitizers on dentin surface does not affect the shear bond strength. CONCLUSION: Dentin desensitizers that alleviate or prevent a dentin tenderness, usually contains HEMA and glutaraldehyde compounds. Such desensitizers are widely used in clinical studies. By applying the dentin desensitizer on the exposed dentin surface, the dentin capillary are blocked and periodontal membrane and cementum can not be drawn in pulp cavity. Since HEMA and glutaraldehyde may cause harm to the pulp cavity, an alternative desensitizer was developed.
Bicuspid
;
Capillaries
;
Crowns
;
Dental Cements*
;
Dental Cementum
;
Dental Prosthesis
;
Dentin*
;
Glass
;
Glutaral
;
Humans
;
Membranes
;
Oxalic Acid
;
Resin Cements
;
Tooth
;
Zinc
10.The Clinical Investigation of the Neonatal Gastric Acidity .
Mi Yun KIM ; Min Ho SUK ; Sin Yoo CHANG ; Wan Sik KIM
Korean Journal of Anesthesiology 1980;13(1):54-57
It is well known that increasing tendency of emergency surgery of congenital snomalies such as tracheoesophageal fistu1a, esophageal atresia, esophageal hiatal hernia, hypertrophic pyloric stenosis,intestinal obstruction, imperforated anus, omphalocele, and meconium ileus by virtue of improvement of pediatric surgical procedure, anesthetic agent, and anesthetic method. The possibility of a low gastric pH and the resultant pulmonary damage if aspirated must be considered in the initial care of the newborn with poor muscle tone or reflex activity as well as in the anesthetic management of neonates. We became interested in the factors determining neonatal gastric pH in this point of view, and have measured gastric pH in 75 unselected neonates, 55 of whom were born vaginally and 20 by cesarean section. In premature infants, pH was high regardless of mode of delivery. In mature infants, pH was 1) significantly lower after vaginal delivery than after cesarean section; 2) tended to be lower after section preceded by labor than after elective section; and 3) was lowest after precipitate delivery. There was no correlation between neonatal gastric pH and duration of rupture of membranes, birth weight, or Apgar score. It was concluded that the mature human fetus produces gastric acidity in response to stresses associated with labor and vaginal delivery.
Anal Canal
;
Apgar Score
;
Birth Weight
;
Cesarean Section
;
Emergencies
;
Esophageal Atresia
;
Female
;
Fetus
;
Gastric Acid*
;
Hernia, Hiatal
;
Hernia, Umbilical
;
Humans
;
Hydrogen-Ion Concentration
;
Ileus
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Meconium
;
Membranes
;
Pregnancy
;
Reflex
;
Rupture
;
Virtues