1.Clinical Observation on Coronary Heart Disease.
Korean Circulation Journal 1971;1(2):1-10
One hundred and seven cases of coronary heart disease were clinically studied at Seoul National University Hospital from September 1967 to August 1971 and following results were obtained. 1. The total cases were composed with 70 cases of myocardial infarction (46 cases of acute type and 24 cases of old type), 26 cases of angina pectoris and 11 cases of coronary insufficiency. 2. The ratio of male to female was 3.5:1, and over two-thirds of patients were sixth and seventh decade in ages. 3. As the underlying diseases, hypertension was found in 38.3% of the cases, and diabetes mellitus in 10.3%. 4. Among the various symptoms, precordial pain was a most common and characteristic, which was noted in 81.1% of the cases. Pain was radiated to the left arm and/or left shoulder in 45.2% of the cases. 5. In 57.2% of the cases, serum cholesterol was more than 200mg%. 6. The ratio between anterior and posterior wall infarction on electrocardiogram was about 3.5:1. 7. Left ventricular hypertrophy was the most frequently noted finding, and sinus tachycardia, low voltage, ventricular premature beat, myocardial ischemia, and others were also observed in some cases. 8. Mortality rate was 8.4%, and the major causes of death were cardiogenic shock and ventricular fibrillation.
Angina Pectoris
;
Arm
;
Cardiac Complexes, Premature
;
Cause of Death
;
Cholesterol
;
Coronary Disease*
;
Diabetes Mellitus
;
Electrocardiography
;
Female
;
Humans
;
Hypertension
;
Hypertrophy, Left Ventricular
;
Infarction
;
Male
;
Mortality
;
Myocardial Infarction
;
Myocardial Ischemia
;
Seoul
;
Shock, Cardiogenic
;
Shoulder
;
Tachycardia, Sinus
;
Ventricular Fibrillation
2.A Study on the Serum Lipoperoxide Level in the Normal Korean and in the Cases with Various Diseases.
Jeong Sik PARK ; Yun Sik CHOI ; Young Woo LEE
Korean Circulation Journal 1979;9(2):37-42
Serum Lipoperoxide levels were studied in 50 normal Korean and in the following patients; 26 patients with diabetes mellitus, 20 patients with hypertension, 14 patients with ischemic heart disease, 8 patients with cerebrovascular accident and 6 patients with nephrotic syndrome. The results obtained are summarized as follows; 1. In normal Korean, the average serum lipoperoxide level was 2.62+/-0.27 nmoles M.D. A./ml, with no difference by the sex. 2. In the cases with various disease which in supposed to be related to abnormal lipid metabolism, that is, diabetes mellitus, hypertension, ischemic heart disease, nephrotic syndrome, the serum lipoperoxide value showed statistically significant elevation compared to that of the normal control (p<0.01), but in the patients with cerebrovascular accident the elevation was not significant (p>0.05). 3. The serum lipoperoxide level was coarsely related with the serum concentration of cholesterol and total lipid, the correlation coefficient of which were 0.34 and 0.35 respectively (p<0.05).
Cholesterol
;
Diabetes Mellitus
;
Humans
;
Hypertension
;
Lipid Metabolism
;
Myocardial Ischemia
;
Nephrotic Syndrome
;
Stroke
3.A Study on the Serum Lipoperoxide Level in the Normal Korean and in the Cases with Various Diseases.
Jeong Sik PARK ; Yun Sik CHOI ; Young Woo LEE
Korean Circulation Journal 1979;9(2):37-42
Serum Lipoperoxide levels were studied in 50 normal Korean and in the following patients; 26 patients with diabetes mellitus, 20 patients with hypertension, 14 patients with ischemic heart disease, 8 patients with cerebrovascular accident and 6 patients with nephrotic syndrome. The results obtained are summarized as follows; 1. In normal Korean, the average serum lipoperoxide level was 2.62+/-0.27 nmoles M.D. A./ml, with no difference by the sex. 2. In the cases with various disease which in supposed to be related to abnormal lipid metabolism, that is, diabetes mellitus, hypertension, ischemic heart disease, nephrotic syndrome, the serum lipoperoxide value showed statistically significant elevation compared to that of the normal control (p<0.01), but in the patients with cerebrovascular accident the elevation was not significant (p>0.05). 3. The serum lipoperoxide level was coarsely related with the serum concentration of cholesterol and total lipid, the correlation coefficient of which were 0.34 and 0.35 respectively (p<0.05).
Cholesterol
;
Diabetes Mellitus
;
Humans
;
Hypertension
;
Lipid Metabolism
;
Myocardial Ischemia
;
Nephrotic Syndrome
;
Stroke
4.Early Clinical Outcome and Complications of Tension Free Vaginal Tape Procedure in Stress Incontinent Women.
Seong Kyoo CHOI ; Jong Min YUN ; You Sik LEE
Korean Journal of Urology 2001;42(6):589-593
PURPOSE: The aim of the study was to evaluate the clinical outcome and complications of tension free vaginal tape (TVT) procedure for the surgical treatment of female stress urinary incontinence. MATERIALS AND METHODS: Between April 1999 and May 2000, 41 women with stress urinary incontinence underwent TVT procedure. Preoperative evaluation included questionnaires study, physical examination, one hour pad test and urodynamic study. Postoperative clinical outcome, patient's satisfaction and complications were checked after 3-months. RESULTS: The mean age of patients was 51.6 years (range 40-76) and mean hospital stay 2.1 days (range 1-10). The mean follow-up period was 9.9 months (range 3-15). Thirty six patients (87.8%) were cured, 2 patients (4.9%) were improved. Two of 3 patients with failed operation who developed postoperative urge incontinence had grade III cystocele. Five bladder perforations and 1 obturator nerve injury occurred. The abdominal leak point pressure (LPP) increased from 50.6cmH20 to 110.8cmH2O, detrusor pressure of maximal flow rate (Pdet.Qmax) increased from 15.8cmH2O to 28.6cmH2O and maximal flow rate (Qmax) decreased from 32.8ml/s to 22.5ml/s after operation. CONCLUSIONS: The TVT procedure is an effective and feasible surgical treatment for female stress urinary incontinence. However, in patients with grade III cystocele, postoperative urge incontinence may develop after the procedure. Since TVT procedure involves securing the mid-urethra, urinary obstruction may also occur, necessitating the need for continued follow-up as well as a careful comparison with other sling procedure.
Cystocele
;
Female
;
Follow-Up Studies
;
Humans
;
Length of Stay
;
Obturator Nerve
;
Physical Examination
;
Surveys and Questionnaires
;
Suburethral Slings*
;
Urinary Bladder
;
Urinary Incontinence
;
Urinary Incontinence, Urge
;
Urodynamics
5.Expression of E-cadherin in Experimental Bladder Carcinogenesis Induced by N-butyl-n-4-hydroxybutyl Nitrosamine.
Yun Chan CHOI ; Eun Sik LEE ; Won Hee PARK
Korean Journal of Urology 2000;41(7):838-843
No abstract available.
Cadherins*
;
Carcinogenesis*
;
Urinary Bladder*
6.Development of B-eNSP (Baptist Electronic Nutritional Screening Program) Using Integrated Medical Information System and Clinical Efficiency.
Sang Min LEE ; Jong Woo CHOI ; Yun Sik LEE
Journal of the Korean Surgical Society 2010;79(Suppl 1):S1-S6
PURPOSE: The aim of this study was to develop a baptist electronic Nutritional Screening Program (B-eNSP) that could be easily used to identify patients with nutrition at risk or malnutrition on their admission to hospital using an integrated medical information system and to evaluate validity, reliability and efficiency of B-eNSP. METHODS: From June 1 2009 to June 21 2009, we enrolled 496 patients for prospective research. We analyzed age, sex, weight, height, weight loss in the last 3 months, serum albumin, alteration of dietary intake, gastrointestinal symptom, functional capacity, diagnosis and its relationship to nutritional requirements, physical examination and Subjective Global Assessment (SGA). B-eNSP included body mass index (BMI), weight loss in the last 3 months, serum albumin. Each component was scored. Sensitivity and specificity were calculated to evaluate the validity of the B-eNSP. The receiver operating characteristic (ROC) curve was drawn by using B-eNSP to choose a cut-off value that maximizes sensitivity and specificity and Yoden Index. Comparison with SGA and the reliability of the B-eNSP was done using kappa statistics. RESULTS: The maximum Yoden Index was 0.866 and the cut-off value of the ROC curve was 2. A B-eNSP score higher than 2 was defined as nutrition at risk or malnutrition. Reliability of the B-eNSP was in accordance with SGA by kappa 0.845. CONCLUSION: The B-eNSP can be used efficiently to identify patients with nutrition at risk or malnutrition by simply using an integrated medical information system.
Body Mass Index
;
Electronics
;
Electrons
;
Humans
;
Information Systems
;
Malnutrition
;
Mass Screening
;
Nutritional Requirements
;
Physical Examination
;
Prospective Studies
;
Protestantism
;
ROC Curve
;
Sensitivity and Specificity
;
Serum Albumin
;
Weight Loss
7.A Case of Primary Adenocarcinoma of the Female Urethra.
Dong Sik CHOI ; Jang Su YUN ; Moo Sik AHN
Korean Journal of Urology 1989;30(2):270-273
We report a case of primary adenocarcinoma of the urethra in 62 years old female. Primary carcinoma of the female urethra is an uncommon malignancy that accounts for less than 0.02 per cent of all cancers occurring in women. Adenocarcinoma is rare in the literature. Whereas squamous cell carcinoma and transitional cell carcinoma, which comprise the majority of urethral malignancies, arise form the squamous or epithelial cells lining the urethra, adenocarcinoma arises form the periurethral glands.
Adenocarcinoma*
;
Carcinoma, Squamous Cell
;
Carcinoma, Transitional Cell
;
Epithelial Cells
;
Female*
;
Humans
;
Middle Aged
;
Urethra*
8.Metabolic Syndrome and Orphan Nuclear Receptor SHP.
Han Jong KIM ; Joon Young KIM ; Kwang Hun SONG ; Yun Yong PARK ; Hueng Sik CHOI
Journal of Korean Society of Endocrinology 2004;19(3):240-249
No abstract available.
Child
;
Child, Orphaned*
;
Humans
9.Coronary and Left Ventricular Angiographic Findings of Acute Myocardial Infarction in Korean Adults.
Seung Yun CHO ; Won Heum SHIM ; Nam Sik CHUNG ; Woong Ku LEE ; Heung Jai CHOI
Korean Circulation Journal 1985;15(3):381-391
To delineate the coronary anatomy and the left ventricular function during early myocardial infarction, coronary arteriography and left ventriculography were performed prospectively in 28(34%) of 83 patients who were admitted to the coronary care unit at Severance Hospital from November 1983 to August 1984 within 30 days(median : 14 days;range : 4 hours to 30 days) after the onset of symptoms. The frequency of total occlusion of the infarct related artery was evaluated in the time course of infarction. To prove spontaneous recanalization, 3 patients who had total coronary occlusion underwent serial study within 11-20 days after the first study. We categorized the patients into two comparable groups according to the infarction site, coronary angiographic findings, and age. Comparison of clinical and angiographic findings between each group was made. The following results were obained. 1) There were 23 patients with transmural myocardial infarction(82.1%) and 5 with nontransmural infarction(17.9%). Among 23 patients with transmural infarction, 14 had anterior infarction(60.9%) and 9(39.1%) inferior infarction. 2) The mean age was 51.3 years(range : 31-79 years). The ratio of male to female was 3.7:1. 3) Fifteen patients(53.6%) had one-vessel disease, 10(35.7%) two-vessel disease and 2(7.1%) three-vessel disease, One patient(3.6%) had insignificant disease(less than 50% reduction in luminal diameter). Nontransmural infarction had a tendency to be associated with higher prevalence of multivessel disease than transmural infarction(80% vs 34.8%). 4) In 23 patients with transmural infarction, 12(52.2%) had complete occlusion and 11(47.8%) incomplete occlusion of the infarct related artery. Three patients(13.0%) had subtotal occlusion(90-99%) and 4(17.4%) had lesions of 70-89% luminal diameter narrowing. Three patients(13.0%) had 50-69% lesions and the remaining 1(4.4%) had insignificant obstructive lesions. 5) Of the 23 patients with transmural infarction, 12 were studied within 14 days and 11 in 15-30 days after the onset of symptoms. The frequency of total coronary occlusion was significantly higher in the patients studied within 14 days of symptom onset vs those studied in the 15-30 days period(83.3% vs 18.2%;p<0.001). Serial studies of 3 patients with total coronary occlusion at the initial study demonstrated occurrance of spontaneous recanalization in 2 patients. 6) The left ventricular-ejection fraction was higher in the patients with nontransmural infarction, inferior infarction, and incomplete coronary occlusion(65+/-14%, 58+/-16% and 57+/-17%) than that of the patients with transmural infarction, anterior infarction, and complete coronary occlusion(51+/-15%, 47+/-14% and 46+/-13, p<0.05). But there was no significant difference in left ventricular ejection fraction between the young(<45 year) and the old(> or =45 year) age groups. And also 0-1 vessel disease and 2-3 vessel disease groups did not show significant difference in ejection fraction. The degree of congestive heart failure was more severe in the patients with anterior infarction than in those with inferior infaction. multi-vessel disease group was significantly older than 0-1 vessel disease group(55+/-8 yrs vs 46+/-12 yrs, p<0.05), and the young age group had a tendency to be associated with higher prevalence of single vessel disease. 7) As for the complications of angiocardiography in this study, there was ventricular finbrillation in 2 patients(7.1%) without mortality. It is concluded that coronary arteriography can be safely performed within one month after acute myocardial infarction;high prevalence of one-vessel disease in acute myocardial infarction in the Korean adult patients admitted to a general hospital;lower incidence of total coronary occlusion in the late time course of infarction due to spontaneous recanalization;better left ventricular function in the patient groups with nontransmural infarction, inferior infarction and incomplete coronary occlusion.
Adult*
;
Angiocardiography
;
Angiography
;
Arteries
;
Coronary Care Units
;
Coronary Occlusion
;
Female
;
Heart Failure
;
Humans
;
Incidence
;
Infarction
;
Male
;
Mortality
;
Myocardial Infarction*
;
Phenobarbital
;
Prevalence
;
Prospective Studies
;
Stroke Volume
;
Ventricular Function, Left
10.Clinical Analysis of Domestic Violence in Emergency Department.
Chul Kyu MOON ; Sung Hyuk CHOI ; Jeung Min JEUN ; Sung Woo LEE ; Yun Sik HONG
Journal of the Korean Society of Emergency Medicine 1998;9(2):311-316
BACKGROUND: Domestic violence once considered an infrequently occurring event existing only in deviant relationships, it has been more recently recognized as a widely distributed phenomenon resulting from multiple cultural, social, psycological factors. According to declining world economics, family violence rises with a simultaneous curtailment of agencies available to assist battered persons and there is increasing pressure on emergency departments to serve those who might otherwise have sought help from public agency. In Korea, we don't have any clinical data about domestic violence, and authors analysed clinical pictures of domestic violence victims who came to the emergency department of Korean University medical center. METHOD: We reviewed the victims of the domestic violence retrospectively, who visited in ED, Korean Univ. Hospital from Jan. 1996 to the Dec. 1996. We Analysed data to Age, sex, Injury severity score, location of injury, mechanism, perpetrator. RESULTS: During the study period, total 134 domestic violence victims were identified. The young, females were predominantly victimized. And married women were more commonly violated. (about 70%). ISS was relatively mild (2.491), face and head were mainly injured by punching and objects throwing. The Prevalence of domestic violence victims almost presented at Emergency department between 6:00/P.M. and 8:00 A.M.. CONCLUSION: Emergency physicians suspect domestic violence victims who injured at face and head by punching or hitted would. In these patients, we need more detail history and physical exam. And in case of repeated domestic violence, refer to neuropychatry dept and social workers with perpetratrs, and need mere concerte social programs for domestic violence.
Academic Medical Centers
;
Domestic Violence*
;
Emergencies*
;
Emergency Service, Hospital*
;
Female
;
Head
;
Humans
;
Injury Severity Score
;
Korea
;
Prevalence
;
Retrospective Studies
;
Social Workers