No abstract available.
Vulva

BACKGOUND: Pulsed dye laser (PDL) is recommended as a good treatment for scars and keloids. However, there has been no absolute indications and standard laser parameters. Some proposed that only hypertrophic and atrophic/flat scars were effectively treated, but others reported that all scars and even keloids responded well to PDL treatment. OBJECTIVE: To determine whether 595nm PDL treatment is effective for scars and keloids, and if so, which group responds better to treatment between the atrophic/flat scars group and hypertropic scars/keloids group. METHOD: Twenty-two patients (skin types III-V) with scars and keloids were treated with 595nm PDL (0.45 or 1.5 msec, 4-8J/cm(2), 7mm spot size). Eleven patients had hypertrophic scars/keloids (6 had hypertropic scars, 5 had keloids), and eleven patients had atrophic/flat scars. After several treatments of each lesion, the results were evaluated by extent of the patient's satisfaction and comparision of pre-and post-laser photography and divided into the four categories: excellent, good, fair and poor. RESULTS: The clinical improvement and patient's satisfaction were better in the atrophic/flat scars group than the hypertrophic scars/keloid group. With keloid potients, the result of treatment were found to be particularly poor. CONCLUSION: From our results, only atrophic/flat scars respond well to 595nm PDL treatment, and hypertrophic scars and keloids should be excluded from this treatments method.
Cicatrix* ; Cicatrix, Hypertrophic ; Humans ; Keloid* ; Lasers, Dye* ; Photography

No abstract available.
Dermatofibrosarcoma* ; Nose*

Background: Patients with undifferentiated masses on the finger are frequently encountered in the clinic. However, dermatology literature is scarce regarding these tumors. Objective: To investigate the clinical characteristics of digital benign tumors. Methods: We retrospectively reviewed clinical photographs and medical records of 139 patients who visited Kangbuk Samsung Hospital for digital tumors confirmed by skin biopsy between January 2013 and August 2019. Results: The mean patient age was 47.6 years and the male-to-female ratio was 1：1.27. The most common digital tumor was mucous cysts, accounting for 32.37% of the total number, followed by pyogenic granuloma (29.49%) and Masson’s hemangioma (7.19%). The most common digital tumors on the volar and dorsal surfaces were pyogenic granuloma (54.09%) and mucous cyst (55.12%), respectively. Conclusion Our study demonstrates that various digital tumors can occur. Further studies with larger patient groups are needed to better understand the incidence or site predilection of digital tumors.

Wolf's isotopic response is defined as the occurrence of a new skin disorder at the site of another unrelated skin disease that has already healed. In most cases of isotopic response, the initial dermatosis is herpes infection, and the most frequent second dermatoses are granulomatous reactions. Various interpretations of this phenomenon have been attempted. However, the exact mechanism has not been identified yet. Herein, we report a case in which the secondary disease was segmental vitiligo that appeared over the same dermatomes of herpes zoster. A 71-year-old woman presented with well-defined, depigmented patches on the left chest and back. She had been diagnosed with herpes zoster on the same dermatomes and treated with an antiviral agent 3 years ago. Histological examination showed decreased basal melanin pigments and melanocytes. Consequently, the patient was diagnosed with segmental vitiligo based on the clinical and histological findings.
Aged ; Female ; Herpes Zoster* ; Humans ; Melanins ; Melanocytes ; Skin ; Skin Diseases ; Thorax ; Vitiligo*

Cytomegalovirus (CMV) infections are usually diagnosed in immunocompromised patients. A 74-year-old male without any significant medical history visited our center because of abdominal pain and diarrhea which began about a month ago. Abdominal computed tomography revealed segmental enhanced bowel wall thickening on jejunum and single-balloon enteroscopy showed multiple geographic shaped ulcerations covered with exudates on proximal jejunum. Biopsy samples taken during endoscopic examination demonstrated necrotic fibrinopurulent tissue debris and benign ulcer. Nested-PCR analysis of CMV DNA from jejunal tissue was positive. The patient was finally diagnosed with CMV jejunitis and was treated by intravenous ganciclovir for 14 days after which, abdominal pain and diarrhea improved. Our case shows that CMV jejunitis can occur in an immunocompetent adult as multiple jejunal ulcers which can be diagnosed using a single-balloon enteroscope.
Aged ; Antiviral Agents/therapeutic use ; Cytomegalovirus/genetics/isolation & purification ; Cytomegalovirus Infections/complications/*diagnosis/drug therapy ; DNA, Viral/analysis ; Endoscopy, Gastrointestinal ; Enteritis/*diagnosis/etiology/virology ; Ganciclovir/therapeutic use ; Humans ; Injections, Intravenous ; Jejunal Diseases/*diagnosis/etiology/virology ; Male ; Polymerase Chain Reaction ; Tomography, X-Ray Computed

We report a case of acneiform skin eruption induced by cetuximab in a 58-year-old man. Cetuximab is a new anticancer agent, which acts as a selective epidermal growth factor receptor monoclonal antibody. Our patient had taken cetuximab for the treatment of metastatic rectal cancer and visited our clinic with multiple erythematous papules and pustules on the face, postauricular area and anterior chest. A skin biopsy from his forehead revealed destruction of the follicular structure and perifollicular inflammatory cellular infiltrations composed of neutrophils and lymphocytes.
Acneiform Eruptions* ; Biopsy ; Forehead ; Humans ; Lymphocytes ; Middle Aged ; Neutrophils ; Receptor, Epidermal Growth Factor ; Rectal Neoplasms ; Skin ; Thorax ; Cetuximab

PURPOSE: This study reports the development of the Korean Version of the Treatment Satisfaction Visual Analogue Scale (TS-VAS) and the Overactive Bladder Satisfaction with Treatment Questionnaire (OAB-SAT-q) based on the original versions, with subsequent linguistic validation by Korean patients with overactive bladder receiving active treatment from a physician. METHODS: Translation and linguistic validation were performed in 2016. The validation process included permission for translation, forward translation, reconciliation, backward translation, cognitive debriefing, and proofreading. The original versions of the TS-VAS and OAB-SAT-q were independently translated into Korean by 2 bilingual translators and were then reconciled into a single version. The third bilingual translator performed a backward translation of the reconciled version into English. A trained interviewer and 5 Korean-speaking patients with OAB carried out the cognitive debriefing. RESULTS: During the forward translation process, the terms used in the 2 questionnaires were adjusted to use more appropriate expressions in the Korean language than were used in the original versions. During the backward translation process, no changes were made in terms of semantic equivalence. In the cognitive debriefing session, 5 patients were asked to fill in the answers within 8 minutes; most of them reported that the translated questions were clear and easy to understand. CONCLUSIONS: The present study presents successful linguistic validation of the Korean version of the TS-VAS and OAB-SAT-q, which could be useful tools for evaluating treatment satisfaction in patients.
Humans ; Linguistics* ; Patient Satisfaction ; Semantics ; Urinary Bladder, Overactive*

Tacrolimus and pimecrolimus represent a new class of topical non-steroidal medication currently used in the treatment of a variety of inflammatory skin lesions. We report a case of a patient in whom topical pimecrolimus therapy resulted in tinea incognito. Mycologic examination, including a KOH smear and fungal culture, was positive for hyphae and colonies of trichophyton mentagrophytes. The lesion was treated with oral griseofulvin and topical clotrimazole.
Clotrimazole ; Griseofulvin ; Humans ; Hyphae ; Skin ; Tacrolimus ; Tinea* ; Trichophyton

BACKGROUND: Sun exposure increases skin cancer risk. However, little is known about general awareness, knowledge and behavior of skin cancer among Korean people. OBJECTIVE: We sought to determine and compare the awareness and knowledge of skin cancer and sun protection behavior among Koreans, foreigners, and doctors, excluding dermatologists. METHODS: A written questionnaire was distributed to 1,091 Koreans, 113 foreigners, and 99 doctors. RESULTS: Most people (68.9%) knew that the sun was dangerous for their skin and the majority of people (59.0%) were aware that sun exposure increased skin cancer risk. However, the general knowledge score of skin cancer for Koreans was limited to half that of foreigners. In other words, Korean people recognized skin cancer, but they had a limited knowledge of detail. The general behavior score of Korean people was about two thirds of that of foreigners. The non-dermatologic doctors' score was similar to that of foreigners. CONCLUSION: Although the majority of Koreans are aware that sun exposure increases skin cancer, they don't seem to have a detailed knowledge of skin cancer prevention or early detection. Therefore, a nation-wide skin cancer education and prevention program is strongly required and dermatologists should play a major role in this program.
Education ; Emigrants and Immigrants ; Humans ; Korea* ; Questionnaires ; Skin Neoplasms* ; Skin* ; Solar System