1.In-vitro cell invasiveness and cytotoxicity of CRMOX-posive and- negative strains of yersinia enterocolitica grown at 26'C and 37'C.
Seog Gee PARK ; Chul Soon CHOI ; Yun Seong JEON
Journal of the Korean Society for Microbiology 1992;27(4):313-324
No abstract available.
Yersinia enterocolitica*
;
Yersinia*
3.Safety of Surgical Tracheostomy during Extracorporeal Membrane Oxygenation.
Hye Ju YEO ; Seong Hoon YOON ; Seung Eun LEE ; Doosoo JEON ; Yun Seong KIM ; Woo Hyun CHO ; Dohyung KIM
Korean Journal of Critical Care Medicine 2017;32(2):197-204
BACKGROUND: The risk of bleeding during extracorporeal membrane oxygenation (ECMO) is a potential deterrent in performing tracheostomy at many centers. To evaluate the safety of surgical tracheostomy (ST) in critically ill patients supported by ECMO, we reviewed the clinical correlation between preoperative coagulation status and bleeding complication-related ST during ECMO. METHODS: From April 1, 2012 to March 31, 2016, ST was performed on 38 patients supported by ECMO. We retrospectively reviewed and analyzed the medical records including complications related to ST. RESULTS: Heparin was administered to 23 patients (60.5%) for anticoagulation during ECMO, but 15 patients (39.5%) underwent ECMO without anticoagulation. Of the 23 patients administered anticoagulation therapy, heparin infusion was briefly paused in 13 prior to ST. The median platelet count, international normalized ratio, and activated partial thromboplastin time before ST were 126 ×109/L (range, 46 to 434 ×109/L), 1.2 (range, 1 to 2.3) and 62 seconds (27 to 114.2 seconds), respectively. No peri-procedural clotting complications related to ECMO were observed. Two patients (5.3%) suffering from ST-related major bleeding required surgical hemostasis. Minor bleeding after ST occurred in two cases (5.3%). No significant difference was found according to anticoagulation management (P = 0.723). No fatality was attributable to ST. CONCLUSIONS: The complication rates of ST in the patients supported by ECMO were low. Therefore, ST performed by an experienced operator, and with careful optimization of coagulation status, is a relatively safe procedure; the use of ST with ECMO should thus not be dismissed on account of the potential for bleeding caused by the administration of anticoagulants.
Anticoagulants
;
Critical Illness
;
Extracorporeal Membrane Oxygenation*
;
Hemorrhage
;
Hemostasis, Surgical
;
Heparin
;
Humans
;
International Normalized Ratio
;
Medical Records
;
Partial Thromboplastin Time
;
Platelet Count
;
Retrospective Studies
;
Tracheostomy*
4.Clinical Characteristics of Respiratory Extracorporeal Life Support in Elderly Patients with Severe Acute Respiratory Distress Syndrome.
Woo Hyun CHO ; Dong Wan KIM ; Hye Ju YEO ; Seong Hoon YOON ; Seung Eun LEE ; Doo Soo JEON ; Yun Seong KIM ; Bong Soo SON ; Do Hyung KIM
Korean Journal of Critical Care Medicine 2014;29(4):266-272
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) strategy is proposed to reduce the ventilator-induced lung injury in acute respiratory distress syndrome (ARDS). As ECMO use has increased, a number of studies on prognostic factors have been published. Age is estimated to be an important prognostic factor. However, clinical evidences about ECMO use in elderly patients are limited. Therefore, we investigated clinical courses and outcomes of ECMO in elderly patients with ARDS. METHODS: We reviewed medical records of patients with severe ARDS who required ECMO support. Study patients were classified into an elderly group (> or = 65 years) and a non-elderly group (< 65 years). Baseline characteristics, ECMO related outcomes and associated factors were retrospectively analyzed according to group. RESULTS: From February 2011 to June 2013, a total of 31 patients with severe ARDS were treated with ECMO. Overall, 14 (45.2%) were weaned from ECMO, 9 (29.0%) survived to the general ward and 7 (22.6%) survived to discharge. Among the 18 elderly group patients, 7 (38.9%) were weaned from ECMO, 4 (22.2%) were survived to the general ward and 2 (11.1%) were survived to discharge. Overall intensive care unit survival was inversely correlated with concomitant acute kidney injury or septic shock. CONCLUSIONS: In this study, ECMO outcome was poor in severe ARDS patients aged over 65 years. Therefore, the routine use of ECMO in elderly patients with severe ARDS is not warranted except in highly selective cases.
Acute Kidney Injury
;
Aged*
;
Extracorporeal Membrane Oxygenation
;
Humans
;
Intensive Care Units
;
Medical Records
;
Patients' Rooms
;
Respiratory Distress Syndrome, Adult*
;
Retrospective Studies
;
Shock, Septic
;
Ventilator-Induced Lung Injury
5.Newly Diagnosed Diabetes Mellitus With Pancreatic Cancer Manifested as Hyperglycemic Hyperosmolar State.
Tae Hyung KWON ; Min Seong KIM ; Jun Ho JEON ; Dong Il JEONG ; Sang Seok YUN ; Yong Kyu LEE
Journal of the Korean Geriatrics Society 2013;17(2):95-98
Here, we report a case of newly diagnosed diabetes, with concurrent pancreatic cancer manifested as hyperglycemic crisis, and aggravated by urinary tract infection. We summarize the initial clinical manifestations and pertinent laboratory, radiologic, and clinical findings in an elderly patient with hyperglycemic emergency. A review of the documents involving pancreatic tumors and hyperglycemic hyperosmolar state, which is an acute complication of diabetes mellitus, is presented. In the absence of other identifiable conditions, it is reasonable to speculate that some factor (or factors) produced by the tumor had a role in the metabolic decompensation. In addition, this discussion should be more carefully considered in the aged people group.
Aged
;
Diabetes Mellitus
;
Emergencies
;
Humans
;
Pancreatic Neoplasms
;
Urinary Tract Infections
6.A Case of Toxic Epidermal Necrolysis Treated with High Dose Intravenous Immunoglobulin in a 2 Years Old Boy.
Se Yun JEON ; Ji Hyung NAM ; Sang Myung HAN ; Kyung Hee RHUE ; Seong Yul LEE ; Joon Soo PARK
Pediatric Allergy and Respiratory Disease 2006;16(2):171-176
Toxic epidermal necrolysis(TEN) is a severe drug induced life-threatening disease and an acute illness. This disease is characterized by rapid onset of widespread necrosis resulting in sloughing of epidermis. The incidence of TEN is very rare, with approximately 0.5 to 1.4 cases per million per year. but TEN has a high mortality rate of 25-40 percent. Therapy for TEN is primarily aimed at supportive care. Treatment with systemic corticosteroid, immunosuppresive agent such as cyclosporine, cyclophosphamide, pentoxifyllin or plasmapheresis have not been shown to improve outcome. Recently, administration of high dose intravenous immunoglobulin(IVIG) has been shown to result in rapid improvement in patients with TEN. There have been several reports of the benefit of IVIG in adult patients with TEN. However we could not find using IVIG in pediatric patient with TEN in Korea. We have experienced improvement in a 2 years old boy with TEN after using high dose IVIG.
Adult
;
Child
;
Child, Preschool*
;
Cyclophosphamide
;
Cyclosporine
;
Epidermis
;
Humans
;
Immunoglobulins*
;
Immunoglobulins, Intravenous
;
Incidence
;
Korea
;
Male*
;
Mortality
;
Necrosis
;
Plasmapheresis
;
Stevens-Johnson Syndrome*
7.The fit of zirconia core fabricated with CAD/CAM system.
Ji Yun SEONG ; Young Chan JEON ; Chang Mo JEONG ; Jang Seop LIM
The Journal of Korean Academy of Prosthodontics 2004;42(5):489-500
STATEMENT OF PROBLEM: The use of zirconia prostheses fabricated with CAD/CAM system is on an increasing trend in dentistry. However, evaluation of the fit related to internal relief and marginal reproducibility of zirconia has not been reported. PURPOSE: This study was to evaluate the fit related to internal relief and marginal reproducibility of zirconia core fabricated with CAD/CAM system. Materials and methods: The evaluation was based on 30 zirconia cores and 5 IPS-Empress2 cores. Zirconia cores were fabricated in different conditions of internal relief(0, 10, 20, 30, 40 and 50 micrometer), and IPS-Empress2 cores were fabricated in accordance with the manufacturer's instructions. Before cementation, the marginal discrepancies of cores were measured on metal die. And then, each core was cemented to stone die, embedded in an acrylic resin and sectioned in two planes(mesiodistally and labiopalatally). The internal gaps were measured at the margin and axial surface. Measurements for the marginal discrepancies, the internal marginal gaps and the internal axial gaps were performed under a measuring microscope(Compact measuring microscope STM5; Olympus, Japan) at a magnification of *100. In addition, the marginal configurations of metal die, zirconia core and IPS-Empress2 core were examined with SEM(S-2700, Hitachi, Japan). RESULTS: Within the limits of this study the results were as follows. 1. Compared with IPS-Empress2 cores, the marginal discrepancies of zirconia cores had no significant differences, the internal marginal gaps were statistically smaller and the internal axial gaps were statistically larger in each condition of internal relief. 2. The marginal discrepancies and the internal marginal gaps of zirconia cores had no significant differences related to the conditions of internal relief(P>0.05). 3. The internal axial gaps of zirconia cores with 0.20micrometer for internal relief were significantly larger than that with 50micrometer(P<0.0001). 4. SEM micrographs showed favorable marginal reproducibility of zirconia core and smooth texture on the milling surface. CONCLUSION: The marginal discrepancy and the internal gaps of zirconia core were clinically acceptable and the milling surface was showed smooth texture. For fabrication of the durable esthetic restoration, further investigations on complex design of core, milling accuracy, compatability of enamel porcelain and porcelain firing seems to be needed.
Cementation
;
Dental Enamel
;
Dental Porcelain
;
Dentistry
;
Fires
;
Prostheses and Implants
8.Evaluation of the Augmentation Cystoplasty in the Pediatric Neurogenic Bladder.
Seong Soo JEON ; Haewon LEE ; Jung Yun JUNG ; Kwan Ryun PARK ; Kyu Sung LEE ; Kwang Myung KIM ; Hwang CHOI
Korean Journal of Urology 1996;37(12):1367-1374
From 1985 to 1995, 13 children with neurogenic bladder underwent augmentation cystoplasty. Diagnosis in these 13 children included Meningomyelocele in 11 and unknown origin in 2. Indications for augmentation cystoplasty were persists incontinence in 6 patients and progressive upper urinary tract deterioration in Bowel segments were used for augmentation included sigmoid colon in 1 patient, ileocecal segments incontinence in 6 patients stomach in 3. Dilated ureter also was used in 1 patient. Postoperatively, all the patients have stable upper tracts radiographically and stable or improved renal function. Of 13 patients 12 require clean intermittent catheterization to empty bladder and 10 are completely continent. After operation, bladder capacity increased from 155 ml to 305 ml and there were significant increases in bladder compliance. Hypereflexia was present in 5 patients before operation and in 3 patients after operation. There has been no surgical mortality. Postoperative complications occurred in 4 patients included mild ileus in 2 patients, mucus obstruction in 1, mild hematuria in 1, metabolic alkalosis in 1 and superficial wound infection in All complications were transient and managed medically. the kind of bowel segments did not seem to influence results. We think that augmentation cystoplasty is a therapeutic modality that should be considered as a viable treatment option in selected patients with neurogenic bladder dysfunction.
Alkalosis
;
Child
;
Colon, Sigmoid
;
Compliance
;
Diagnosis
;
Hematuria
;
Humans
;
Ileus
;
Intermittent Urethral Catheterization
;
Meningomyelocele
;
Mortality
;
Mucus
;
Postoperative Complications
;
Stomach
;
Ureter
;
Urinary Bladder
;
Urinary Bladder, Neurogenic*
;
Urinary Tract
;
Wound Infection
9.Pregnancy Outcome of Natural and In-vitro Fertilization Twin Pregnancy.
Yun Jin KIM ; Hyung Min CHOI ; Seong Hoon HONG ; Woon Hee SUH ; Byeong Jun JUNG ; Myung Kwon JEON ; Eung Soo LEE
Korean Journal of Perinatology 2001;12(4):480-485
No abstract available.
Female
;
Fertilization*
;
Humans
;
Pregnancy
;
Pregnancy Outcome*
;
Pregnancy*
;
Pregnancy, Twin*
10.Facet Joint Injuries in Acute Cervical Spine Trauma: Evaluation with CT and MRI.
Jeon Ju HA ; Dong Hyun KIM ; Jeong Hwa LEE ; Keon LEE ; Hyeok Po KWON ; Jung Hyeok KWON ; Seong Mun YUN
Journal of the Korean Radiological Society 1999;40(5):957-963
PURPOSE: To evaluate injury patterns of facet joints and associated soft tissue injuries in patients withacute traumatic cervical facet joint injuries. MATERIALS AND METHODS: From among patients with cervical spinetrauma, 27 with facet joint injuries, as seen on CT and MRI, were chosen for this study. CT scans were analyzedwith regard to the location of facet joint injury, the presence or absence of facet dislocation or fracture, andother associated fractures. MR images were analyzed with regard to ligament injury, intervertebral disc injury,intervertebral disc herniation, and spinal cord injury. RESULTS: The most common location of facet joint injurywas C6-7 level(n=10), followed by C5-6(n=8). Among these 27 patients with facet joint injuries, 12(44%) hadbilateral injuries and 15(56%) unilateral injuries. Facet fractures were present in 17 cases(63%) and the fractureof inferior facet was more frequent than superi-or. Patterns of fracture were vertical, transverse, or comminuted,but vertical fracture was the most common. Various degrees of dislocation were observed in patients with facetfractures. Fractures other than facet includ-ed pillar(n=11), lamina(n=6), transverse process(n=14), body(n=13),and spinous process(n=3). On MR im-ages, anterior longitudinal ligament injury was found in 8 patients(30%),posterior longitudinal ligament injury in 4(15%), and interspinous ligament injury in 20(74%). Twelvepatients(44%) had spinal cord injuries includ-ing edema(n=8) and hemorrhage(n=4). Among patients with discabnormalities, 11(41%) had intervertebral disc injuries, and traumatic disc herniations were found in nine. CONCLUSION: Traumatic cervical facet joint injuries were manifested as various patterns and frequentlyassoci-ated with other fractures or soft tissue injuries. Analysis of CT and MR findings of these injury patternshelped formulate a therapeutic plan and determine of prognosis.
Dislocations
;
Humans
;
Intervertebral Disc
;
Ligaments
;
Longitudinal Ligaments
;
Magnetic Resonance Imaging*
;
Prognosis
;
Soft Tissue Injuries
;
Spinal Cord Injuries
;
Spine*
;
Tomography, X-Ray Computed
;
Zygapophyseal Joint*