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The soft tissue sarcoma ih the Orthopedic surgery is not common, occuring in less than one percent of all malignant tumors. Whille the sarcoma is comparatively highly malignant, its treatment has been varied, and the effect of the each treatment has been controversial and generally poor on statisties. We studied 58 cases of soft tissue sarcoma in the Orthopedic department of Pusan Gospei Hospital in the 6 years period from March, 1975 to March, 1981. We confirmed the sarcoma diagnosis by biopsy, and measured the size, the degree of local infilteration and occurrence of metastasis with the help of plain X-ray, angiography, lung and bone scan, and computerized tomograms. We made treatment plans according to above results. We classified the soft tissue sarcoma into 8 histologic types and obtained following conclusions: l. Among the 58 cases of soft tissue sarcoma, and majority is consisted of fibrosarcoma, liposarcoma and rhabdomyosarcoma. 2. There were 41 cases occurred in the lower extremity and 17 cases in the upper extremity. Thus soft tissue sarcoma are more frequent in the lower extremity, especially in thigh (2 patients). 3. We found 19 cases between the age of 41 to 50 years. In general, the soft tissue sarcoma are more frequent between the age of 31 to 50 years. 4. Among the 58 cases, 10 patient came to our hospital because of recurrence of soft tissue sarcoma, after receiving local excision in other hospitals. In other words 17 percent of our cases showed recurred sarcoma and duration of recurrence was within 16 months. 5. Metastasis of the soft tissue sarcoma had taken place in 17 patients (29%), most frequently metastasis to the lung in 12 cases (70%). 6. We treated 30 cases by chemotherapy and radiotherapy after excision or amputation. In 15 sarcomas that could not be excised, but the medical treatment with chemotherapy and radiotherapy. 7. The follow-up study revealed better result obtained in the group of aggresive treatment with anticancer chemotherapy and radiotherapy after excision or amputation.
Amputation ; Angiography ; Biopsy ; Busan ; Clinical Study ; Diagnosis ; Drug Therapy ; Fibrosarcoma ; Follow-Up Studies ; Humans ; Liposarcoma ; Lower Extremity ; Lung ; Neoplasm Metastasis ; Orthopedics ; Radiotherapy ; Recurrence ; Rhabdomyosarcoma ; Sarcoma ; Thigh ; Upper Extremity

6.Efficacy of 1 % Butenafine Hydrochloride Cream in the Treatment of Tinea Pedis.

Sang Tae KIM ; Kee Suck SUH ; Yun Kyew KIM

Korean Journal of Dermatology 1995;33(2):287-293

BACKGROUND: Topical 1% butenafine hydrochloride cream, a new benzylamine derivative, has been reported to have antimycotic effect. OBJECTIVE: An open trial as conducted to assess the efficacy and safety of 1% butenafine hydrochloride cream used once daily in the treatment of tinea pecis. METHODS: Of 45 patients with clinically and mycologically proertinea pedis from the department of dermatology at Kosin medical college hospital, 42 patient, who could be monitored to the end of this study were evaluated. They applied 1% butenafine hydrochloride cream once daily until clinical improvement became evident or for 4 weeks and the effects were evaluated clinically and mycologically. RESULTS: 1. From the mycological studies at the initial visit, causative organisms were isolated from 36 patients out of the 42 subjects and Trichophyton rubrum was most comnmon organism. 2. The negative conversion rate of the mycological study( negative microscopy and negative culture) was 90.5%(38/42) after 4 weeks of treatment. 3. The effective treatment vate at 4 weeks was 90.5%(38/42) 4. A adverse effects of using 1% butenafine hydrochloride cream was noted in 1 patient, who had a moderate degree of puritus, out of the 42 subjects. The presritus disappeared soon after the cessation of application of the cream. CONCLUSION: 1% butenafine lydrochloride cream is effective andafe in the treatment of tinea pedis.
Dermatology ; Humans ; Microscopy ; Tinea Pedis* ; Tinea* ; Trichophyton