No abstract available.
Korea* ; Vaccination*

No abstract available.
Anti-Bacterial Agents* ; Dysentery, Bacillary*

No abstract available.
Anemia, Hemolytic* ; Child* ; Humans

No abstract available.
Bronchiectasis* ; Humans ; Infant*

Thirty percutaneous liver biopsy and one liver necropsy were reviewed in Severance Hospital, Yonsei University from June 1979 to September 1980. This procedure is the safe and accurate means of diagnosing and studying liver diseases in the pediatric patients especially persistent conjugated hyperbilirubinemia, chronic liver disease, and some rare diseases (eg. Histiocytosis-X, Storage disease disease, Gilbert syndrome), The significance of the technique and following results were obtained. 1. Among 31 cases, 14 cases were under 1 year of age 21 cases were male. 2. Evaluation of persistent neonatal conjugated hyperbilirubinemia, chronic hepatitis, Gaucher's disease, gilbert syndrome, congenital hepatic fibrosis, portal hypertension, and Histiocytosis-X were possible by the pathologic findings of percutaneous liver biopsy speciments. 3. Pathologic findings of 10 cases of neonatal conjugated hyperbilirubinemia are Giant cell hepatitis (4), acute hepatitis (1), acute fulminant hepatitis (1), extrahepatic biliary atresia (2), intra hepatic biliary hypoplasia (2), and hepatic fibrosis (1), Causative agents are hepatitis virus B (4), toxoplasma gondii (2), herpes simplex (1), syphilis (1), unknown (2). 4. One case of acute fullminent hepatitis due to herpes simplex was confirmed by electronmicroscopic study of the specimen. 5. One case of tuberculous empyema of the liver was confirmed by the discovery of tuberculi bacilus on the direct smear of the biopsy speciments, although the pathologic findings showed non specific findings of reactive hepatitis. 6. There was nonspecific information in systemic disease and hepatomegaly with fever of unko\nown origine. 7. There was no complication in 30 cases of percutaneous liver biopsy.
Biliary Atresia ; Biopsy* ; Empyema, Tuberculous ; Fever ; Fibrosis ; Gaucher Disease ; Giant Cells ; Gilbert Disease ; Hepatitis ; Hepatitis Viruses ; Hepatitis, Chronic ; Hepatomegaly ; Herpes Simplex ; Histiocytosis, Langerhans-Cell ; Humans ; Hyperbilirubinemia ; Hypertension, Portal ; Liver Diseases ; Liver* ; Male ; Needles* ; Rare Diseases ; Syphilis ; Toxoplasma

We observed 285 cases of culture proved shigellosis from Jan. 1978 to July 1981 at W.M.B.H. in Busan. We specially observed the clinical and bacteriological response to Oxolinic acid in 59 cases from Jan. to July 1981. The following results were obtained. 1. The most commonly isolated shigella strains was Sh. flexneri (85.3%) followed by Sh. sonnei (7.4%), Sh. boydii (4.2%) and Sh. dysenteriae(3.2%). 2. Antibiotic sensitivity test revealed that more than 90% of strains were resistant to Tetracycline, Chloramphenicol and Ampicillin. Resistance strains to Gentamycin and Oxocid were found in less than 12.2% and 14.3% respectively. 3. The multiple antibiotic resistant strains were observed in about 80% of 59 strains, which were resistant to 3~5 antibiotics. The most of these strains were resistant to Ampicillin, Chloramphenicol and Tetracycline. In 3 cases it was resistant to all kinds of antibiotics but oxolinic acid. 4. Oxolinic acid showed growth-inhibitory zone of more than 11 mm with the concentration of 2mcg/ml in 95% and M.I.C. value of less than 0.76mcg/ml in 90%. 5. After administration of Oxolinic acid, there was clinical response within 2 days in 76.5% and conversion to negative stool culture within 2days in 68.8%. 6. Compared with placebo group, there was parallel clinical and bacteriologic effectiveness between Oxolinic acid and Rifampin.
Ampicillin ; Anti-Bacterial Agents ; Asthma* ; Busan ; Chloramphenicol ; Dermatitis, Atopic* ; Dysentery, Bacillary ; Gentamicins ; Oxolinic Acid ; Rifampin ; Shigella ; Tetracycline

We observed 285 cases of culture proved shigellosis from Jan. 1978 to July 1981 at W.M.B.H. in Busan. We specially observed the clinical and bacteriological response to Oxolinic acid in 59 cases from Jan. to July 1981. The following results were obtained. 1. The most commonly isolated shigella strains was Sh. flexneri (85.3%) followed by Sh. sonnei (7.4%), Sh. boydii (4.2%) and Sh. dysenteriae(3.2%). 2. Antibiotic sensitivity test revealed that more than 90% of strains were resistant to Tetracycline, Chloramphenicol and Ampicillin. Resistance strains to Gentamycin and Oxocid were found in less than 12.2% and 14.3% respectively. 3. The multiple antibiotic resistant strains were observed in about 80% of 59 strains, which were resistant to 3~5 antibiotics. The most of these strains were resistant to Ampicillin, Chloramphenicol and Tetracycline. In 3 cases it was resistant to all kinds of antibiotics but oxolinic acid. 4. Oxolinic acid showed growth-inhibitory zone of more than 11 mm with the concentration of 2mcg/ml in 95% and M.I.C. value of less than 0.76mcg/ml in 90%. 5. After administration of Oxolinic acid, there was clinical response within 2 days in 76.5% and conversion to negative stool culture within 2days in 68.8%. 6. Compared with placebo group, there was parallel clinical and bacteriologic effectiveness between Oxolinic acid and Rifampin.
Ampicillin ; Anti-Bacterial Agents ; Asthma* ; Busan ; Chloramphenicol ; Dermatitis, Atopic* ; Dysentery, Bacillary ; Gentamicins ; Oxolinic Acid ; Rifampin ; Shigella ; Tetracycline

A 13-year-old boy was diagnosed as having primary nephrogenic diabetes insipidus, and symptoms developed at 3 years of age. Subsequently he developed bilateral hydronephrosis and a neurogenic bladder. His pedigree could be explored back 5 generations and represented an inheritance as an X-linked recessive transmission factor. He was treated with indomethacin 2 mg/kg/day plus chlorothiazide 500 mg/day and this new treatment showed a markedly decreased urine output and increased urine osmolarity. (Nephrogenic diabetes insipidus, Hydronephrosis, Indomethacin)
Adolescent ; Bladder, Neurogenic/etiology ; Chlorothiazide/therapeutic use ; Diabetes Insipidus/complications ; Diabetes Insipidus/congenital* ; Diabetes Insipidus/drug therapy ; Diabetes Insipidus/genetics ; Drug Therapy, Combination ; Human ; Hydronephrosis/etiology* ; Indomethacin/therapeutic use* ; Male

No abstract available.
Angioplasty* ; Child* ; Humans ; Takayasu Arteritis*

A 13 year old boy was diagnosed as primary nephrotic diabetesinsipidus, whose symptom has been devloped from 3 years of age, subsequetly he developed bilateral hydronephrosis and neurogenic bladder. His pedigree could be explored 5 generations and represented inheritace as X-linked recesslive transmission, He was treated with indomethacin 2mg/Kg/day plus chlorothiazid 500mg/dau and this new method shows markedly decreased urine outpur and increased urine osmolarity.
Adolescent ; Diabetes Insipidus, Nephrogenic* ; Family Characteristics ; Humans ; Hydronephrosis ; Indomethacin ; Male ; Osmolar Concentration ; Pedigree ; Urinary Bladder, Neurogenic