1.Undifferentiated Gallbladder Carcinoma with Osteoclast-like Giant Cells: A Case Report.
Korean Journal of Pathology 2007;41(2):127-131
Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) is the least common type of gallbladder carcinoma. Here, the author presents a case of undifferentiated gallbladder carcinoma with OGCs in an 81-year-old male patient. Grossly, the tumor was a 10x7 cm sized, polypoid, lumen-filling mass with extensive hemorrhage and necrosis. Microscopically, the tumor was composed of pleomorphic ovoid to spindle cells admixed with numerous OGCs. There was a minute focus of mucosal dysplasia and carcinoma in situ. Immunohistochemically, the mononuclear cells were positive for cytokeratin, p53 and Ki-67, while the OGCs were negative for these markers but positive for CD68. These findings support an epithelial origin for the ovoid to spindle cells and the nonneoplastic reactive histiocytic lineage of the OGCs.
Aged, 80 and over
;
Carcinoma
;
Carcinoma in Situ
;
Gallbladder*
;
Giant Cells*
;
Hemorrhage
;
Humans
;
Keratins
;
Male
;
Necrosis
;
Osteoclasts
2.Cytologic Heterogeneity of Signet Ring Cell Carcinoma of the Stomach: Histochemical and electron microscopic observations.
Korean Journal of Pathology 1992;26(5):427-435
The cytologic heterogeneity of the tumor cells in gastric signet ring cell carcinoma was studied with 13 surgically early gastric carcinoma specimens by means of histochemical stainings on mucin(periodic acid Schiff-alcian blue at pH 2.5, paradoxical concanavalin A, high iron diamine) and electron microscopy. Of the 13 cases of early gastric cell carcinomas, 6 were mucosal type and 7 were submucosal type. Eleven cases consisted of mixture of gastric and intestinal type signet ring cells and the remaining 2 of the mucosal type were entirely made of gastric type. The colonic goblet cell type was found in 4 of the submucosal type. Within the mucosa the tumor cells showed a layering phenomenon; type A signet ring cells were distributed at the central zone and type B and C at the superficial or deeper zone. Each type of signet ring cell showed variable mucin histochemical stainability of gastric and/or intestinal nature. Above finding strongly suggest that the variable phenotypes of signet ring cells result from a heterogeneity of cytoplasmic mucin as well as different stages of differentiation of signet ring carcinoma cells.
3.Ceruminous Gland Tumors: 5 cases report.
Korean Journal of Pathology 1994;28(4):414-419
Tumors of the ceruminous gland are rare. However, careful histologic evaluation and classification are necessary for the proper treatment and ultimate prognosis. We present 5 cases of ceruminous gland tumors. Case l (73/M) and case 2 (52/M) were adenoid cystic carcinoma. They presented with protuding masses in the left external auditory canal for several months. Case 3 (76/M) was a mucoepidermoid carcinoma of auditory canal, who presented with right ear swelling. The mass recurred 3 years after the surgical resection and combined radiation therapy. Case 4 (60/F) and case 5 (2l/F) were ceruminous adenoma, which showed diffuse or focal areas of glandular structures with one-or two-layer of eosinophilic columnar to cuboidal cells and sometimes with myoepithelial cells. These tumors showed non-infil-trative growth pattern and lack of mitosis, and had no capsule.
4.Training satisfaction according to the type of family practice residency program.
Yun Ju KANG ; Mi Kyung OH ; Young Jin LEE
Journal of the Korean Academy of Family Medicine 1992;13(11):869-877
No abstract available.
Family Practice*
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Humans
;
Internship and Residency*
5.A Study of the cPR Training Course for Nurse Teachers and Ambulance Drivers.
Kyung Hee KANG ; young Soo HAN ; Jung Yun HWANG
Journal of the Korean Society of Emergency Medicine 1997;8(3):353-361
No abstract available.
Ambulances*
;
Cardiopulmonary Resuscitation*
6.Fine needle aspiration cytology of malignant ameloblastoma metastasized to the lung-a case report-.
Yun Kyung KANG ; In Ae PARK ; Chang Yun LIM ; Eui Keun HAM ; Sang Kook LEE
Korean Journal of Cytopathology 1993;4(2):167-170
No abstract available.
Ameloblastoma*
;
Biopsy, Fine-Needle*
7.Cellular Schwannoma Arising in a Facial Nerve.
Mee JOO ; Hye Sung KIM ; Yun Kyung KANG ; Hye Kyung LEE ; Jae Young PARK
Korean Journal of Pathology 1997;31(7):688-691
Cellular schwaninoma is a variant of schwannoma, which is characterized by predominance of cellular Antoni A area, presence of mitotic activity, nuclear hyperchromasia, pleomorphism, and absence of Verocay body. These pathologic features often prompted a misdiagnosis of malignancy. However, the clinical outcome has indicated the benignity of the tumor. We have experienced a case of cellular schwannoma arising from right facial nerve with right hemifacial weakness and erosion of mastoid process. Grossly, it was a 3.5 x 3 cm sized and relatively well encapsulated mass with yellowish, friable cut surface. Microscopically, cellular growth with moderate cellular pleomorphism and some mitotic activity (5/40 HPFS, up to 2/HPF) were noted. Immunostaining for S-100 protein showed diffuse strong positive reaction.
Diagnostic Errors
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Facial Nerve*
;
Mastoid
;
Neurilemmoma*
;
S100 Proteins
8.Quantitative assessment of the diameters of tricuspid valve, mitral valve and great arteries in the normal human fetus.
Jung Yun CHOI ; Kyung Hee PARK ; Chung Il NOH ; Yong Soo YUN ; I Seok KANG ; Eun Sook HAN
Journal of the Korean Pediatric Society 1992;35(11):1566-1572
No abstract available.
Arteries*
;
Echocardiography
;
Fetus*
;
Heart
;
Humans*
;
Mitral Valve*
;
Tricuspid Valve*
9.Esophagus, Stomach & Intestine; Adenocarcinoma Arising from Barrett's Esophagus: A case report.
Jin Kyung KANG ; Chung Bae KIM ; Ho Guen KIM ; Jeong Yun SHIM
Korean Journal of Gastrointestinal Endoscopy 1997;17(2):151-154
Barrett's esophagus is a metaplastic process in which the squamous epithelium of the lowet esophagus is replaced by columnar epithelium. Most cases are believed to be related to prolonged gastroesophageal reflux. Detection of Barretts esophagus is important in that it results in adenocarcinoma in about 10% of patients. We report a case of adenocarcinoma arising from Barrett's esophagus in a 56 year-old man, diagnosed incidentally at a physical check-up. Grossly, the esophagogastric junction was irregular and there were two small ulcers in the lower esophagus. Microscopically, ihe squamous epithelium of the lower hagus was replaced by specialized intesinal mucosa with a small focus of adenocarcinona confined to the submucosa in one area. Many separate dysplastic foci were also present in the nearby esophageal mucosa.
Adenocarcinoma*
;
Barrett Esophagus*
;
Epithelium
;
Esophagogastric Junction
;
Esophagus*
;
Gastroesophageal Reflux
;
Humans
;
Intestines*
;
Middle Aged
;
Mucous Membrane
;
Stomach*
;
Ulcer
10.A Case of Metastatic Adenocarcinoma on the Scalp from the Rectum.
Hun Young JANG ; Yun Seo KANG ; Hye Kyung AN ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 1995;33(1):179-182
Cutaneous metastatic tumors on the scalp from the rectum are very A 66-year-old male presented a nodule and papule an his scalp three months after surgical removal of a rectal adenocarcinorna. Biopsy specien from the scalp showed adenocarcinoma which is similar to the primary rectal carcinoma.
Adenocarcinoma*
;
Aged
;
Biopsy
;
Humans
;
Male
;
Rectum*
;
Scalp*