1.The Changes in Axial and Radial Diffusivity in a Patient with Clinically Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion
Investigative Magnetic Resonance Imaging 2020;24(3):174-177
Multiple studies have established that mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) exhibits reversible diffusion restriction in the white matter, including the splenium. There have been a few previous reports of the change in fractional anisotropy (FA) of MERS cases. Herein, we report the longitudinal changes in axial and radial diffusivity (AD and RD), and FA in a 15-year-old boy patient with MERS. Our case demonstrated that a MERS lesion had a significant drop of AD in the early period and gradual recovery. On the contrary, RD did not show any significant change.
2.A Case of Terra Firma-forme Dermatosis Treated with CO₂ Laser.
Ji Won YUN ; Kyung Ho LEE ; Chul Jong PARK
Korean Journal of Dermatology 2017;55(8):547-549
No abstract available.
Skin Diseases*
3.Oncology Nurses' Knowledge of Safety Guidelines and Compliance with Safe Handling of Antineoplastic Agents in a Tertiary Hospitall.
Asian Oncology Nursing 2016;16(4):251-260
PURPOSE: The purpose of this study was to identify the knowledge and compliance of guidelines for safe handling of antineoplastic agents among the oncology nurses. METHODS: The participants were 186 nurses from oncology-hematology unit, and outpatient's infusion room in a tertiary hospital. The levels of knowledge of safety guidelines and compliance with safe handling of antineoplastic agents of oncology nurses were measured using structured questionnaires from October 1 to November 30, 2014. RESULTS: Oncology nurses' knowledge of guideline for safe handling of antineoplastic agents presented an average 79.7 out of 100 points. Compliance with safe handling of antineoplastic agents presented an average 4.28 (range: 2.9~5) out of 5 points. The knowledge of guidelines for safe handling of antineoplastic agents was related with oncology experience (F=3.78, p=.012). There were positive relationships of knowledge and compliance with safe handling of antineoplastic agents (r=0.23, p=.002). CONCLUSION: The findings showed that there was a need to establish efficient guidelines for the safe handling of antineoplastic agents and develop our structured, continuous educational program for the improvement of safe practices related to the handling of antineoplastic agents. The developed and enhanced that guideline and educational program would contribute to improvement of staff and patient safety related to the handling of antineoplastic agents.
Antineoplastic Agents*
;
Compliance*
;
Patient Safety
;
Tertiary Care Centers*
4.Pelvic, Hip, and Knee Kinematics of Stair Climbing in People with Genu Varum
Yun Won CHAE ; Seol PARK ; Ji Won PARK
Journal of Korean Physical Therapy 2018;30(1):14-22
PURPOSE: This study examined the effects of the lower limb alignment on the pelvis, hip, and knee kinematics in people with genu varum during stair walking. METHODS: Forty subjects were enrolled in this study. People who had intercondylar distance ≥4cm were classified in the genu varum group, and people who had intercondylar distance < 4cm and intermalleolar distance < 4cm were placed in the control group. 3D motion analysis was used to collect the pelvis, hip, and knee kinematic data while subjects were walking stairs with three steps. RESULTS: During stair ascent, the genu varum group had decreased pelvic lateral tilt and hip adduction at the early stance phase and decreased pelvic lateral tilt at the swing phase compared to the control group. At the same time, they had decreased minimal hip adduction ROM at the early stance and decreased maximum pelvic lateral tilt ROM and minimum hip rotation ROM at the swing phase. During stair descent, the genu varum group had decreased pelvic lateral tilt at the early stance and decreased pelvic lateral tilt and pelvic rotation at the swing phase. In addition, they had decreased pelvic frontal ROM during single limb support and increased knee sagittal ROM during the whole gait cycle. CONCLUSION: This study suggests that a genu varum deformity could affect the pelvis, hip and knee kinematics. In addition, the biomechanical risk factors that could result in the articular impairments by the excessive loads from lower limb malalignment were identified.
Biomechanical Phenomena
;
Congenital Abnormalities
;
Extremities
;
Gait
;
Genu Varum
;
Hip
;
Knee
;
Lower Extremity
;
Pelvis
;
Range of Motion, Articular
;
Risk Factors
;
Walking
5.Association between betaARK1 Level of Circulating Mononuclear Leukocytes and Left Ventrcular mass in Non-treated Hypertensive Patients.
Bong Ryong CHOI ; Eun Ji KIM ; Ji Eun LEE ; Ji Cheol YUN ; Jung Hee NAM ; Seong Ji PARK ; Jin Yong HWANG ; Dong Ju CHOI ; Bong Gwan SEO
Korean Circulation Journal 2000;30(12):1530-1539
BACKGROUND: Beta-adrenergic receptor Kinase 1(betaARK1) is a serine/threonine kinase attached, which inhibits the coupling of beta-adrenergic receptor with G-protein. Myocardial betaARK1 level is usually elevated in heart failure and hypertrophy, but it is not known whether the circulating betaARK1 level is related with the degree of cardiac hypertrophy. This study was performed to evaluate the association of the betaARK1 level in circulating mononuclear leukocytes(MNL) in untreated hypertension with left ventricular mass in hypertensive patients. Method: Nineteen non-treated hypertensive patients were included for this study. High blood pressure was confirmed when systolic BP is over 150 mmHg or diastoli BP is over 95 mmHg. Echocardiography was performed to evaluate the degree of hypertrophy by measuring the left ventricular mass index(LVMI) and relative wall thickness(RWT), and test the LV function by measuring the ejection fraction(EF) according to ASE guideline. At the same time, blood was collected from each patient and MNL were isolated by gradient centrifuge with Ficoll-400. Total RNA was purified from MNL and semi-quantitative RT-PCR was performed. After reverse transcription, PCR was done with primers for human betaARK1 and GAPDH as external control. betaARK1 levels were expressed by ratio to GAPDH level and estimated the relations with clinical and Echocardiographic parameters. Result: We studied confirmed 19 hypertensive patients(10 men and 9 women, mean age of 50.6 years). Echocardiographically measured indices(mean+/-SD) were as follows; LVMI(137.3+/-30.6g/m2), PWT(0.53+/-0.09) and EF(54.6+/-8.5%). Ratio of betaARK1 levels to GAPDH was from 0.10 to 0.96 (0.62+/-0.25). betaARK1 levels were correlated with LVMI(correlation coefficient: r=.502, p=.029) and RWT(r=.627, p=.004). But Systolic BP(r=0.009, p=.93), diastolic BP(r=.07, p=.85) or EF(r=.045, p=.84) were not related to level of betaARK1. CONCLUSIONS: The betaARK1 level of circulating MNL was correlated well with the degree of the cardiac hypertrophy estimated by LVMI and RWT. This data suggests that activation of sympatho-adrenal system would exert a major role in developing cardiac hypertrophy and we can expect the decreased responsiveness to catecholamine in the heart of hypertensive patients. betaARK1 in circulating MNL might be used as a predictor or marker for LV hypertrophy in hypertensive patients.
beta-Adrenergic Receptor Kinases
;
Cardiomegaly
;
Echocardiography
;
Female
;
GTP-Binding Proteins
;
Heart
;
Heart Failure
;
Humans
;
Hypertension
;
Hypertrophy
;
Leukocytes, Mononuclear*
;
Male
;
Phosphotransferases
;
Polymerase Chain Reaction
;
Reverse Transcription
;
RNA
6.Lower Leg Salyage Orccedure in Massive Bone & Soft Tissue Defects: Combined Free Flap&Lixarov Destraction Osteogenesis.
Dae Hyun LEW ; Ji Yung YUN ; Kwan Chul TARK ; Beyoung Yun PARK ; Hak Sun KIM ; Kyun Hyun YANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):938-944
The treatment of massive bone and soft tissue defect in the lower leg has a high complication rate of nonunion, chronic infection, and amputation without well-vascularized tissue coverage of the open fracture. Despite adequate free soft tissue coverage, massive skeletal defect may result in segmental bone defects, angulation deformity, and limb length discrepancies. In the last decade, major advances have occurred in the Ilizarov method of distraction osteogenesis in lower leg salvage as a delayed procedure or simultaneous distraction after free-tissue transfer. The authors have performed Ilizarov transport in conjunction with muscle and musculocutaneous flap coverage in nine cases of lower leg salvage. The flaps consist of rectus, gracilis, latissimus dorsi, parascapular, and serratus muscle or musculocutaneous fashioning using ipsilateral or contralateral pedicle in consideration of vessel condiation. Revision, recorticotomy and flap elevation were also used as a secondary procedure for satisfactory results. The conclusions, were as follows: 1) Multidisciplinary team approach with conjoining departments at the time of preoperative evaluation, postoperative care and rehabilitation care; 2) Muscle flap covered with split-thickness skin graft was preferred to musculocutaneous flap; 3) To reduce the total reconstructive period, simultaneous free tissue transfer with Ilizarov distraction should be considered.
Amputation
;
Congenital Abnormalities
;
Extremities
;
Fractures, Open
;
Ilizarov Technique
;
Leg*
;
Myocutaneous Flap
;
Osteogenesis*
;
Osteogenesis, Distraction
;
Postoperative Care
;
Rehabilitation
;
Skin
;
Superficial Back Muscles
;
Transplants
8.Atrophy of Multifidus Muscle on Low Back Pain Patients.
Ji Hye BAE ; Jin Kyung NA ; Ji Yun YU ; Yong Ok PARK
Journal of the Korean Academy of Rehabilitation Medicine 2001;25(4):684-691
OBJECTIVE: To investigate the correlation of multifidus muscle atrophy on MRI findings with clinical findings in low back pain patients. METHOD: Medical records of 80 patients presenting with low back pain were retrospectively reviewed. Their MR images were visually analysed to know lumbar multifidus muscle atrophy, disc herniation, disc degeneration, spinal stenosis and nerve root compression. RESULTS: Multifidus muscle atrophy increased from the upper lumbar level to the most caudal intervertebral level. It was bilateral in the majority of the cases. Multifidus muscle atrophy was well correlated with patient's age, referred leg pain, and disc degeneration. However, duration of low back pain, disc herniation, spinal stenosis, nerve root compression, sex, weight, height and BMI had no correlation with multifidus muscle atrophy. CONCLUSION: Examination of multifidus muscle atrophy should be considered when assessing MR images of lumbar spine. It may help for further evaluation and planning the treatment modalities of low back pain.
Atrophy*
;
Humans
;
Intervertebral Disc Degeneration
;
Leg
;
Low Back Pain*
;
Magnetic Resonance Imaging
;
Medical Records
;
Muscular Atrophy
;
Paraspinal Muscles*
;
Radiculopathy
;
Retrospective Studies
;
Spinal Stenosis
;
Spine
9.Antitumor components of the cultured mycelia of calvatia craniformis.
Byong Kak KIM ; Ji Yun KWUN ; Young In PARK ; Jin Woo BOK ; Eung Chil CHOI
Journal of the Korean Cancer Association 1992;24(1):1-18
No abstract available.
10.Radiographic Characteristics of Male Breast Cancer.
Shin Ho KOOK ; Ki Keun OH ; Tae Hoon KIM ; Chang Yun PARK ; Ji Hyung KIM
Journal of the Korean Radiological Society 1995;32(4):667-671
PURPOSE: Our objective was to evaluate mammographic findings of breast cancer in men. MATERIALS AND METHODS: This study includes 9 man with breast cancer diagnosed pathologically by radical mastectomy. Clinical and pathologic data were obtained by review of patients' medical record. Mammograms were analysed retrospectively. RESULTS: Of the 9 patients, eight had masses with spiculated margin or schirrous pattern with irregular margin. One patient had no specific evidence of breast cancer mammographically. Microcalcifications were seen in three patients, these calcifications were irregular in shape and were clustered. Of the 8 cases, four patients had the masses at the right breast, four at the left breast. Locations of breast cancer were subareolar(n=4) and were eccentric(n=4) from the nipple. The most common location was the upper outer quadrant. On histologic evaluation, 7 cases were infiltrating ductal carcinomas, one case was mucinous adenocarcinoma, and the remainder was proved as combined form of intraductal and infiltrating ductal carcinoma. Axillary lymph node metastasis were found in 4 cases. CONCLUSION: Mammographic findings of male breast carcinoma were that of subareolar or eccentrically located mass. Calcifications were same to the patterns of calcification as female breast cancer.
Adenocarcinoma, Mucinous
;
Breast
;
Breast Neoplasms
;
Breast Neoplasms, Male*
;
Carcinoma, Ductal
;
Female
;
Humans
;
Lymph Nodes
;
Male
;
Male*
;
Mastectomy, Radical
;
Medical Records
;
Neoplasm Metastasis
;
Nipples
;
Retrospective Studies