Most insects including the honeybee cause erythema and edema at the site of a sting in non-allergic individuals. This reaction usually resolves within a few days. However, in certain cases, the persistence of inciting materials in the cutaneous tissue may promote a local inflammatory foreign body reaction. Localized nodular lesions were seen in our two patients and erythemstous patches were present in one patient due to rarely encountered complications induced by retained sting materials. In these cases histopathology showed multiple foci of foreign body granuloma containing yellow refraetile material in the center surrounded by histiocytes and foreign body giant cells. The granulomatous skin lesions in these patients were treated with intralesional injections of triamcinolone acetonide and partial excisions of the nodular masses were performed.
Bites and Stings ; Edema ; Erythema ; Foreign-Body Reaction ; Giant Cells, Foreign-Body ; Granuloma* ; Granuloma, Foreign-Body ; Histiocytes ; Humans ; Injections, Intralesional ; Insects ; Skin ; Triamcinolone Acetonide

Blood glucose homeostasis is well maintained by coordinated control of various hormones including insulin and glucagon as well as cytokines under normal conditions. However, chronic exposure to diabetic environment with high fat/high sugar diets and physical/mental stress can cause hyperglycemia, one of main characteristics of insulin resistance, metabolic syndrome, and diabetes. Hyperglycemia impairs organogenesis and induces organ abnormalities such as cardiac defect in utero. It is a risk factor for the development of metabolic diseases in adults. Resulting glucotoxicity affects peripheral tissues and vessels, causing pathological complications including diabetic neuropathy, nephropathy, vessel damage, and cardiovascular diseases. Moreover, chronic exposure to hyperglycemia can deteriorate cognitive function and other aspects of mental health. Recent reports have demonstrated that hyperglycemia is closely related to the development of cognitive impairment and dementia, suggesting that there may be a cause-effect relationship between hyperglycemia and dementia. With increasing interests in aging-related diseases and mental health, diabetes-related cognitive impairment is attracting great attention. It has been speculated that glucotoxicity can result in structural damage and functional impairment of brain cells and nerves, hemorrhage of cerebral blood vessel, and increased accumulation of amyloid beta. These are potential mechanisms underlying diabetes-related dementia. Nutrients and natural food components have been investigated as preventive and/or intervention strategy. Among candidate components, resveratrol, curcumin, and their analogues might be beneficial for the prevention of diabetes-related cognitive impairment. The purposes of this review are to discuss recent experimental evidence regarding diabetes and cognitive impairment and to suggest potential nutritional intervention strategies for the prevention and/or treatment of diabetes-related dementia.
Adult ; Alzheimer Disease* ; Amyloid ; Blood Glucose ; Blood Vessels ; Brain ; Cardiovascular Diseases ; Cognition ; Cognition Disorders ; Curcumin ; Cytokines ; Dementia ; Diabetes Mellitus ; Diabetic Neuropathies ; Diet ; Glucagon ; Hemorrhage ; Homeostasis ; Humans ; Hyperglycemia ; Insulin ; Insulin Resistance ; Mental Health ; Metabolic Diseases ; Organogenesis ; Risk Factors

A rare case of uterine lipoleiomyoma is reported with presentation of computed tomography, histomorphologic and immunohistochemical findings. This tumor is predominantly lipomatous with an admixture of smooth muscle fiber and hyalinized fibrous tissue. Immunohistochemical study revealed a positive reaction of S-100 protein in fat cells and desmin in smooth muscle fibers. Its histogenesis also has been discussed.

PURPOSE: This study was designed to verify effects of perineal care with aroma essential oil on urinary tract infection(UTI) in patients with indwelling urinary catheter. METHOD: The research design was non equivalent control group pretest-post test design. The data were collected from March to August, 2005 at C university hospital in Seoul. The subjects were 43 patients who had a indwelling catheter in neurosurgery intensive care unit(NSICU). They were assigned to two groups, 21 subjects to the experimental group and 22 subjects to the control group. The experimental group received perineal care with 3% blending essential oil for 4 days. RESULTS: In the experimental group, white blood cells and bacteria in urine were significantly lower than control group. Bacteria in urine culture was lower in the experimental group at post test. CONCLUSION: Perineal care with aroma essential oil could be an effective intervention to reduce the UTI of patients in NSICU.
Aromatherapy ; Bacteria ; Catheters, Indwelling ; Humans ; Critical Care ; Leukocytes ; Neurosurgery ; Research Design ; Seoul ; Urinary Catheters* ; Urinary Tract Infections* ; Urinary Tract*

OBJECTIVE: To determine the prevalence and associated factors of kidney disease in Korean rheumatoid arthritis (RA) patient, and describe the profile of RA drugs prescribed in RA patients. METHODS: A total of 284 patients at the division of rheumatology with confirmed RA were prospectively included in this study from May 1 to August 31, 2008. Renal function was assessed using Cockcroft-Gault (CG) and abbreviated Modification of Diet in Renal Disease (aMDRD) study formulae, and classified by the National Kidney Foundation (NKF) classification. Comparisons was were performed by the two sample t-test, chi-square-test and binary logistic regression analysis. RESULTS: Of 281 patients with RA, only 7 (2.5%) patients had abnormal serum creatinine (sCr) levels. According to the NFK classification, the prevalence of kidney disease using aMDRD and CG formula was 23.8% and 31.7%, respectively. Among the patients with eGRF <60 mL/min/m2 according to aMDRD or CG formulae, 91.8~100% received at least one drug that was potentially nephrotoxic. RA patients with renal dysfunction was associated with advanced age, body mass index (BMI), antinuclear antibody (ANA). CONCLUSION: Estimation of renal function with CG or aMDRD formulae is important in RA patients, particularly in those with low BMI or old age. Also, appropriate dosage adjustment is needed in patients with renal dysfunction.
Antibodies, Antinuclear ; Arthritis, Rheumatoid ; Body Mass Index ; Creatinine ; Diet ; Humans ; Kidney ; Kidney Diseases ; Logistic Models ; Prevalence ; Prospective Studies ; Rheumatology

PURPOSE: The aim of this study was to identify the status of psychological health among boys in high school and to examine the mediating effects of social support on the relationship between anger and entrapment on psychological health. METHODS: The participants in this study were 193 high school boys from Jeju. Measurements included state-trait anger expression inventory, entrapment scale, student social support scale, and questionnaires to assess mental and physical health. Data were analyzed using independent t-test, one-way ANOVA, Scheffé test, Pearson correlation coefficient, simple and multiple regression techniques with the SPSS 21.0. Mediation analysis was performed with the Baron and Kenny's method, and Sobel test. RESULTS: Mean scores for anger experience, entrapment, social support, and psychological health were 29.81±7.34, 34.09±16.33, 45.75±7.02, 22.51±9.91, respectively. There was a significant correlation between anger experience and psychological health. Entrapment was significantly correlated with psychological health. Social support showed partial mediating effects in the relationship between anger experience and psychological health (Sobel test: Z=54.18. p<.001). Social support showed partial mediating effects in the relationship between entrapment and psychological health (Sobel test: Z=2.24. p=.025). CONCLUSION: The results indicate a need to develop social support programs for boys in high school.
Adolescent ; Anger* ; Constriction ; Humans ; Methods ; Negotiating* ; Psychology

Pigmented lesions of palmar and plantar skin may cause diagnostic problems, because some features of benign lesions in these sites may raise the suspicion of melanoma if considered alone. Transepidermal elimlnation is a mechanism by which a substance is eliminated through the epidermis, and it is apt to be confused with a feature of melanoma that tumor cells are located at all layers of the epidermis. We report a case of transepidermal elimination of nevus cells in acral letiginous nevus which needs a differential dignosis of melanoma.
Epidermis ; Melanoma ; Nevus* ; Skin

No abstract available.
Colon* ; Polyps*

PURPOSE: The purpose of this study was to develop a mentoring program for stress management among Korean adolescents and to assess the effects of the program. METHODS: The nonequivalent control group (CG) pretest-posttest design was used in this study. The mentoring intervention was delivered to 18 middle school students (males and females) but nothing was done to the control group consisting of 18 students. The mentoring intervention was conducted by seven nursing students who participated in the program as mentors using various methods such as individual meetings and group activities. The dependent variable was stress level. RESULTS: The program consisted of group and individual mentoring. At follow-up, although the mentees's satisfaction was high and they stated qualitatively positive experience, the difference of stress level between the two groups was not significant. CONCLUSION: If future mentoring programs reflect the limitation of the current program, they may have potential as developmentally appropriate interventions for stress management of adolescents, and enable nursing students to gain confidence in their professional capability.
Adolescent* ; Follow-Up Studies ; Humans ; Mentors* ; Students, Nursing

BACKGROUND: HLA-B40 is the most frequently identified HLA-B type in Koreans. Also HLA-B60 and B61 are the serologic split antigens of HLA-B40. But because of the lack of mono-specific alloantisera, cross reactivity of sera used as typing reagents, and poor antigenicity of some specific cells such as cord blood lymphocytes, discrimination between HLA-B60 and B61 has been often problematic in laboratories. In this study, authors evaluated whether the PCR-SSP method can be useful for accurate assignments of HLA-B60 and B61 or not. METHODS: Twenty-nine lymphocytes samples which were suspected as heterozygotes or homozygotes of HLA-B60 or B61 and three samples typed as HLA-B40 are selected from stored cord blood and organ transplantation donors. HLA types of these samples were defined by serologic method using a commercial typing kit. PCR that amplified exons 2 and 3 of the HLA-B gene using sequence specific primer pairs exactly matched to HLA-B60 or B61 allele making up a serological specificity was done. RESULTS: A clear discrimination between B60 and B61 was possible in all samples including 9 serologically ambiguous samples. Discrepancy between serologic typing and molecular typing was seen in three cases identified serologically as B40 positive but inable to define a split. Among three samples, two were identified as HLA-B61 and one was identified as HLA-B60. CONCLUSIONS: Molecular typing was useful in discriminating between HLA-B60 and B61. The PCR-SSP method for HLA-B60 and B61 including other cross-reactive HLA types will be helpful as a supplemental method of the serologic typing.
Alleles ; Discrimination (Psychology)* ; Exons ; Fetal Blood ; Heterozygote ; HLA-B Antigens ; HLA-B40 Antigen ; Homozygote ; Humans ; Indicators and Reagents ; Lymphocytes ; Molecular Typing ; Organ Transplantation ; Polymerase Chain Reaction* ; Sensitivity and Specificity ; Tissue Donors ; Transplants