Low back pain patients an controls of shipyard workers were surveyed between June 1995 and september 1995 to identify risk factors of industrial low back pain. The patients were 17 male workers who had got medical treatment for over 3 days because of industrial back pain controls were 51 male workers who had not have musculoskeletal disorder for one year before the survey. By univariate analysis, the workers who did overtime work 4 times or more for the last 2 weeks showed odds ratio of 3.67 on low back pain with the workers who did less overtime work. Carrying heavy materials was also associated with the low back pain and the odds ratio increased with the increase of carrying weight. work space and work posture were not associated with the low back pain significantly. The welder had higher odds ratio than the other workers on low back pain. The duration of employment and job satisfaction did not affect the risk of low back pain. Multiple logistic regression analysis showed that frequency of overtime work for the last 2 weeks and carrying heavy materials among the risk factors were associated significantly with the low back pain. We found that important risk factors of low back pain of shipyard workers are work intensity factors such as overtime work and carrying heavy weight.
Back Pain ; Employment ; Humans ; Job Satisfaction ; Logistic Models ; Low Back Pain* ; Male ; Odds Ratio ; Posture ; Risk Factors*

Genotoxic agents can induce various DNA lesions. DNA-Protein Crosslinks(DPCs) were known as the important DNA lesions which could impair gene expression because DPCs had a high probability of resisting repair and persisting through cell cycle. This repair resistance of DPCs could have biological significance but had not been evaluated clearly yet. Most of the studies that have evaluated the repair of DPCs only compared the extent of DPCs repair with other DNA lesions. We injected K2CrO4, a genotoxic agent, into Sprague-Dawley rats intraperitoneally(5mg/kg) and isolated blood lymphocytes 12 hours later. These lymphocytes were cultured in the mitogen added growth media and mitogen free media separately. The degree of the repair of DPCs was monitored for 4 days by the K-SDS assay. 4 day later, the amount of DPCs decreased by 4.6% in the mitogen added media but in creased by 10.9% in the mitogen free media. These results showed that DPCs induced by K2CrO4 were not repaired easily and the DPCs were biologically significant DNA lesions. We thought the decrease of DPCs in the mitogen added media was not due to the repair of DPCs, but from the increase of normal cell proliferation. Therefore, it is very important to consider the proliferation of normal cells when estimating the repair of DPCs.
Animals ; Cell Cycle ; Cell Proliferation ; DNA ; Gene Expression ; Lymphocytes* ; Rats* ; Rats, Sprague-Dawley

Majolin's ulcer is a carcinomatous ulcer from degenerating burn scars. This patient is a 44 year-old man who has been suffering from pain and itching sensation on Rt. wrist of burn scars. Symptom has been developed since 18 months ago. Skin lesion is a well defined, slight brownish colored, scaly verrucous surfared plaque with reddish ringlike border and oozing tendency in small part. On physical examination, he is in within normal limit excepet burn scar on Rt. upper extremity. He was received burn with gasolin at the age of seven. Biopsy on the skin lesion revealed well differentiated squamous cell carcinoma appearance. Diagnosis was confirmed by the history and histopathological finding. Literature was briefly reviewed.
Adult ; Biopsy ; Burns ; Carcinoma, Squamous Cell ; Cicatrix ; Diagnosis ; Humans ; Physical Examination ; Pruritus ; Sensation ; Skin ; Ulcer* ; Upper Extremity ; Wrist

No abstract available.

Most insects including the honeybee cause erythema and edema at the site of a sting in non-allergic individuals. This reaction usually resolves within a few days. However, in certain cases, the persistence of inciting materials in the cutaneous tissue may promote a local inflammatory foreign body reaction. Localized nodular lesions were seen in our two patients and erythemstous patches were present in one patient due to rarely encountered complications induced by retained sting materials. In these cases histopathology showed multiple foci of foreign body granuloma containing yellow refraetile material in the center surrounded by histiocytes and foreign body giant cells. The granulomatous skin lesions in these patients were treated with intralesional injections of triamcinolone acetonide and partial excisions of the nodular masses were performed.
Bites and Stings ; Edema ; Erythema ; Foreign-Body Reaction ; Giant Cells, Foreign-Body ; Granuloma* ; Granuloma, Foreign-Body ; Histiocytes ; Humans ; Injections, Intralesional ; Insects ; Skin ; Triamcinolone Acetonide

No abstract available.
Child* ; Heart Diseases* ; Heart* ; Humans ; Mass Screening*

No abstract available.
Neurilemmoma*

Single photon emission computed tomographic(SPECT) imaging, performed at oral and maxillofacial surgery department, is valuable in assessing temporomandibular dysfunction, looking for metastases in patients with malignancies, diagnosing facial asymmetry. Conventional planar scintigraphy is limited by two-dimensional representation of three-dimensional structures. The SPECT exam, by sectioning through a distribution of tracer, eliminates the obscuring effects of tracer located outside the plane of interest. In our department, we used this image for four type cases retrospectively. 1. Those patients who have facial asymmetry 2. To find metastases in patients with malignacies 3. In combination with magnetic resonance imagine, to confirm the diagnosis of internal joint derangement 4. To evaluate the viability of grafted bone. Recently, this image is able to be used in those patients whose symptoms etiology cannot be explained by other diagnostic techniques.
Diagnosis ; Facial Asymmetry ; Humans ; Joints ; Neoplasm Metastasis ; Radionuclide Imaging ; Retrospective Studies ; Surgery, Oral ; Tomography, Emission-Computed, Single-Photon* ; Transplants

Because of advances of technologies in the field of genomic epidemiology in the recent years, specimen collection, storage and analysis became an essential part of research methodologies. DNA is now being used in epidemiologic studies to evaluate genetic risk factors and specimens other than the fresh whole blood can be used for PCR. Therefore, All nucleated cells, such as buccal swabs and urine specimens, are suitable for DNA analysis. For an unlimited source of genomic DNA, EBV transformation of lymphocytes can be used for immortalization. However, the type of specimen collected in genomic epidemiologic studies will depend on the study where the epidemiologist play a leading role for the design. We also briefly described various kinds of analysis for SNP that is an essential part of the genomic epidemiology.
Biological Specimen Banks ; DNA ; Epidemiologic Studies ; Epidemiology* ; Genome ; Herpesvirus 4, Human ; Lymphocytes ; Molecular Epidemiology ; Polymerase Chain Reaction ; Polymorphism, Single Nucleotide ; Risk Factors ; Specimen Handling

No abstract available.
Cheek*