No abstract available.

PURPOSE: PVP using a high-power potassium-titanly-phosphate(KTP) laser offers safe and efficacious surgical therapy for men with symptomatic BPH. To demonstrate its efficacy, safety and durability, we present the results of PVP for treatment of BPH with 12 month follow-up. MATERIALS AND METHODS: 104 consecutive men with symptomatic BPH underwent PVP with an 80 W KTP laser (Laserscope) between July 2003 and August 2004. All underwent preoperative and postoperative evaluation, including assessments of international prostate symptom score(IPSS), quality of life(QOL), peak urinary flow rate(Qmax), post-void residual volume(PVR), prostate specific antigen(PSA), and ultrasound prostate volume(PV). Secondary outcome parameters included surgical time, anesthesia, and length of catheterization. Follow-up assessment occurred at 1, 3, 6, and 12 months. Data were analyzed using the Wilcoxon signed rank test. RESULTS: Preoperative mean PV was 57.2+/-4.2 ml. PV decreased to 38.9, 35.4, 32.8 and 35.8 at 1, 3, 6 and 12 months (p <0.01 versus preoperative value). Mean improvements in IPSS, QOL, Qmax, and PVR at 12 months were 67%, 81%, 138% and 94%, respectively(p <0.001). Mean operative time was 26.3+/-15.0 minutes. Anesthesia included pudendal and prostatic block(n=102) and spinal anesthesia(n=2). Ninety-nine(95%) patients were treated as outpatients( <12 hrs) and the remaining 5 patients were admitted for 1 or 2 hospital days. Mean catheterization times were 9.8+/-3.1 hours(range 0~72), with 28(27%) patients not requiring a catheter post-operatively. Minor complications included mild hematuria lasting 3 weeks(3.8%), transient post-operative retention(2.9%), urge incontinence(1.9%), transient dysuria(25%), frequency(21.2%), urgency(17.3%) and retrograde ejaculation(41%). CONCLUSIONS: These results demonstrate that PVP is safe and efficacious for the treatment of symptomatic BPH. Long follow-up will further validate this new modality as the standard for surgical treatment of BPH.
Anesthesia ; Catheterization ; Catheters ; Follow-Up Studies ; Hematuria ; Humans ; Lasers, Solid-State* ; Male ; Operative Time ; Prostate ; Ultrasonography ; Volatilization*

No abstract available.
Cystitis, Interstitial* ; Dimethyl Sulfoxide*

No Abstract Available.
Humans ; Infant* ; Korea* ; Rotavirus* ; Sequence Analysis*

BACKGROUND: The multifactorial hypothesis is proposed as a working hypothesis which encompass both the genetic and environmental factors known to participate in the etiology of congenital heart anomalies. So, at the moment, it is believed that avoidance of suspected environmental factors in early pregenancy is most certain preventive measure of congenital heart anomalies. This study has been undertaken in order to find the possible environmental risk factors for congenital heart anomalies in Korea. METHOD: A total of 320 mothers of infants with congenital heart anomalies diagnosed at Seoul National University Hospital were included in this study as case group. And 413 mothers of healthy infants, who visited well baby clinic at the hospital during the same period of 2 years from 1987, comprised the control group. Data related to environmental risk factors including drug use during the first trimester of pregnancy, any other confounders were collected by direct interview using questionmaires. RESULT: There were positive associations for lower educational level of mother, indoor smoking habit of father, number of pregnancy, and of experience of previous abortion of mother, and multiple(or twin) birth. Relative risk estimates for the first trimester exposure to anti-emetics and herb medicine were 2.1(p<0.006) and 1.4(p<0.044), respectively. Data showed a positive association between anti-inflammatory drug exposure and congenital anomalies of pulmonary valve(OR=22.7, p<0.01), and between anti-histamine exposure and coarctation of aorata(OR=12.7, p<0.017). CONCLUSION: Environmental factors such as smoking habit of father, certain drugs used in early pregnancy, plays a role in the etiology of congenital heart anomlaies. Further studies, designed to focus on specific drug and to differentiate the effect of the suspected drug and to differentiate the effect of the suspected drug form that of the underlying conditions prompting its use, should be called upon.
Abortion, Induced ; Antiemetics ; Case-Control Studies* ; Fathers ; Female ; Heart* ; Humans ; Infant ; Korea* ; Mothers ; Parturition ; Pregnancy ; Pregnancy Trimester, First ; Risk Factors ; Seoul ; Smoke ; Smoking

BACKGROUND: Adenosine has gained wide popularity in the emergency medical service system(EMS) since its approval for use in the treatment of paroxysmal supraventricular tachycardia(PSVT). But, few study about its efficacy and safety have been reported in this country. Therefore we had studied the efficacy of adenosine in the patients with PSVT in the emergency department(ED). METHOD: A prospective outcome study was performed from July, 1996 to June, 1997 at the Sanggye Paik Hospital. Inje University. PSVT was diagnosised based on emergency physician's interpretation of the 12 channel ECG. patient's age, sex, symptoms, systolic blood pressure, heart rate, elapse time to sinus rhythm and side effects were recorded. RESULTS: Twenty seven cases received adenosine for diagnosed PSVT in the ED for 1 year. The cases were 6 man and 21 women. The mean age was 53.4 years old. Three cases were considered unstable PSVT. In twenty six cases(96.3%) were converted to normal sinus rhythm after adenosine therapy. None of the patients who converted to sinus rhythm had recurrent PSVT or required additional medication. Various adverse effects of adenosine were noted in all patients but were transient and clinically insignificant. CONCLUSION: Intrvenous adenosine is an effective, safe and urgent treatment PSVT and no significant side effects were happened in emergency department.
Adenosine* ; Blood Pressure ; Diagnosis ; Electrocardiography ; Emergencies* ; Emergency Medical Services ; Emergency Service, Hospital* ; Female ; Heart Rate ; Humans ; Outcome Assessment (Health Care) ; Prospective Studies ; Tachycardia*

No abstract available.
Internet* ; Korea

BACKGROUND: Demodicosis is a parasitic skin disease caused by Demodex mites, and the determination of mite density per square centimeter is important to diagnose demodicosis. Standardized skin surface biopsy (SSSB) and direct microscopic examination (DME) are commonly used to determine Demodex mites density (Dd). However, no study has previously compared these two methods with respect to clinical types and distribution patterns of demodicosis. OBJECTIVE: The aim of this study was to compare the value of SSSB and DME findings in reference to the clinical types and distribution patterns of demodicosis. METHODS: The medical records of 35 patients diagnosed with demodicosis between December 2011 and June 2015 were retrospectively reviewed. Demodicosis was classified according to four clinical types (pityriasis folliculorum, rosacea type, acne type, and perioral type) and three distribution patterns (diffuse pattern, U-zone pattern, and T-zone pattern). Two samples, one for SSSB and one for DME, were obtained from a lesion of each patient. RESULTS: In all patients, mean Dd and the proportion with a high Dd (>5D/cm²) by DME (14.5±3.3, 80.0%, respectively) were higher than by SSSB (5.5±1.3, 37.1%, respectively; p<0.01, p=0.02, respectively). In terms of clinical types, for rosacea type, mean Dd and proportion with a high Dd by DME (12.4±3.5, 84.6%, respectively) were significantly greater than those determined by SSSB (3.6±1.2, 23.1%; p=0.04, p=0.04, respectively). In terms of distribution pattern, for the diffuse pattern, mean Dd and the proportion with a high Dd by DME (17.5±3.7, 100%, respectively) were significantly higher than those determined by SSSB (6.0±2.7, 26.7%; p<0.01, p<0.01, respectively). CONCLUSION: The results of our study revealed that DME is a more sensitive method for detecting Demodex than SSSB, especially in patients with diffuse pattern and suspected rosacea type. Further research is needed to confirm this finding.
Acne Vulgaris ; Biopsy* ; Humans ; Medical Records ; Methods ; Mites* ; Retrospective Studies ; Rosacea ; Skin Diseases, Parasitic ; Skin*

BACKGROUND: Although neuromuscular blockade can influence the bispectral index (BIS) during anesthesia, there have been contradictory reports regarding its effects. The purpose of this study was to investigate whether a muscle relaxant affected the level of BIS during propofol anesthesia. METHODS: Forty-eight healthy patients undergoing elective surgery under general anesthesia were enrolled in this prospective, randomized, double-blind study. All patients received an effect-site targeted concentration of propofol via a TCI system that was titrated until loss of consciousness occurred. The patients then received either an injection of vecuronium (relaxant group, n = 24) or normal saline as a placebo (placebo group, n = 24) at 3 minutes after loss of consciousness. The BIS and electromyogram (EMG) activity were recorded from anesthetic induction to 4 minutes after injection of the vecuronium or placebo. RESULTS: The BIS significantly decreased after injection in both groups (P < 0.05), however, the decrease in the BIS was larger in the relaxant group than in the placebo group (P < 0.05). The decrease of EMG activity was not significantly different between the two groups after administration of vecuronium or placebo. CONCLUSIONS: During propofol induction of anesthesia, a muscle relaxant decreased BIS significantly without decreasing the EMG activity.
Anesthesia ; Anesthesia, General ; Double-Blind Method ; Humans ; Muscles ; Neuromuscular Blockade ; Propofol ; Prospective Studies ; Unconsciousness ; Vecuronium Bromide

PURPOSE: In recent year, erectile dysfunction patients are increasing, and some of them want to increase their erectile function without using medication or surgical methods, In this study we attempted to find the value of electrical stimulation with electrical stimulation machine Hi-DREAM 328(TM) made in Korea as a treatment method of no definite underling disease caused erectile dysfunction patients. MATERIALS AND METHODS: In 22 cases erectile dysfunction patients we treated them two times per week for 4 weeks totally 8 times above mentioned machine, each session was spent for 1 hour 48 minutes. We checked IIEF-5 (International Index of Erectile Function-5) score repeatedly for comparing the change of IIEF-5 score pretreatment, 1 month after treatment and 3 month after treatment. And we compared the effect of treatment as comparing the IIEF-5 score changing each time. RESULTS: Total IIEF-5 score of pretreatment was 9.6+/-5.5, 1 month and 3 month after electrical stimulation were 17.9+/-2.9, 16.2+/-2.9, respectively. In the patients with venous leakage, IIEF-5 score was no increase definitely following electrical stimulation. But in the case of abnormal SPACE, pretreatment of IIEF-5 score was 12.1+/-5.2, 1 month and 3 month after electrical stimulation were 18.1+/-7.6, 16.5+/-7.4, respectively. We found that IIEF-5 score were increased in no definite organic caused erectile dysfunction patients, and there was significant correlation statistically (p<0.05) in erectile function, maintenance of erection, intercourse satisfaction, overall satisfaction. The remaining effect after treatment was decreased in time follow up. But the erectile function was preserved at comparing before treatment. CONCLUSIONS: We suggest that electrical stimulation is one of the treatment modalities in the treatment of no definite underling disease caused erectile dysfunction patients rather than vascular abnormalities as like venous leakage.
Electric Stimulation* ; Erectile Dysfunction* ; Follow-Up Studies ; Humans ; Korea ; Male