1.Susceptibility to Antivirals of a Human HBV Strain with Mutations Conferring Resistance to Both Lamivudine and Adefovi.
Yun Jung CHANG ; Myung Seok LEE
The Korean Journal of Gastroenterology 2005;46(4):316-317
No abstract availble
2.Tricuspid Regurgitation in Heart Diseases in Infants and Children.
Hye Kyung HAN ; Yong Soo YUN ; Chang Yee HONG
Korean Circulation Journal 1988;18(1):127-134
Doppler echocardiography was performed to evaluate the tricuspid regurgitation in 786 infants and children with heart disease. 3 Doppler methods were used. : The duration of systolic turbulence of tricuspid regurgitation in thr right atrium was evaluated by continuous wave Doppler method, the distance of systolic turbulence within right atrium from the tricuspid plane, by pulsed Doppler method and the retrograde systolic hepatic vein regurgitation, by color Doppler method. The following results were obtained. 1) Incidence of pan systolic tricuspid regurgitation in each disease were as follows. 68% of ECD, 66% of Ebstein's anomaly, 54% of pulmonary atresia, 50% of arrhythmia, 45% of ASD, 38% of TAPVR, 15% of VSD, 26% of TOF, 12% of PDA, 13% of normal children. 2) In about 90% of children with tricuspid regurgitation, hepatic vein regurgitation was detected by color Doppler echocardiography.
Arrhythmias, Cardiac
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Child*
;
Ebstein Anomaly
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Echocardiography, Doppler
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Echocardiography, Doppler, Color
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Heart Atria
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Heart Diseases*
;
Heart*
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Hepatic Veins
;
Humans
;
Incidence
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Infant*
;
Pulmonary Atresia
;
Scimitar Syndrome
;
Tricuspid Valve Insufficiency*
3.Prevalence and subtype distribution of HPV infection among women in Beijing urban area and their correlation with age.
Ping HONG ; Pei-Chang WANG ; Yun-Xiu ZHANG ; Pin HAN
National Journal of Andrology 2014;20(8):719-722
OBJECTIVETo investigate the prevalence and subtype distribution of human papillomavirus (HPV) infection and its correlation with age among women in Beijing urban area, and provide some epidemiological evidence for the clinical application of HPV vaccines.
METHODSWe collected cervical specimens from 1999 women in the Outpatient Department of our hospital, performed genetyping of HPV-DNA, and analyzed the incidence of HPV infection in different age groups.
RESULTSHPV infection was detected in 502 (25.2%) of the 1999 women patients, with 391 (19.6%) cases of high-risk HPV, which included 326 (83.4%, 326/391) cases of single infection. HPV-16 was the most common type (21.2%, 69/326), followed by HPV-52 (19.3%, 63/326) and HPV-58 (16.0%, 52/326). The prevalence of HPV infection was the highest among the women aged 41 -50 years and the lowest among those over 60 years.
CONCLUSIONThe subtype- and age-specific distribution of HPV infection among women in Beijing urban area shows an obvious heterogeneity, which deserves due consideration in the clinical application of HPV vaccines.
Adolescent ; Adult ; Age Distribution ; Aged ; China ; epidemiology ; Female ; Genotype ; Humans ; Middle Aged ; Papillomaviridae ; classification ; genetics ; Papillomavirus Infections ; epidemiology ; Young Adult
4.Larsen's syndrome: A Case Report
Byeong Mun PARK ; Chang Dong HAN ; Yun Tae LEE
The Journal of the Korean Orthopaedic Association 1985;20(6):1202-1206
Larsen's syndrome is a very rare deformity, which is characterized by multiple congenital dislocations with a characteristic facial abnormality. The authors experienced a case of typical Larsen's syndrome that had saddle nose, hypertelorism, high-arched palate, dislocation of the hip joint, subluxation of the knee joint, dislocation of both radial heads, equinovarus deformities of both feet and winged scapulae of both shoulders. The dislocated left hip joint was reduced surgically and the result was excellent.
Clubfoot
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Congenital Abnormalities
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Dislocations
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Foot
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Head
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Hip Joint
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Hypertelorism
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Knee Joint
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Nose
;
Palate
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Scapula
;
Shoulder
5.Advances on chemical constituents and bioactivities of genus Stellera.
Yun-yun YE ; Lu HAN ; Ping WEI ; Guo-zhu SU ; Tian-tian SU ; Chang-cai BAI
China Journal of Chinese Materia Medica 2015;40(22):4324-4332
Advance on chemical constituents and pharmacological activities of Stellera plants have been conducted. The chemical constituents include terpenes, coumarins, flavonoids, lignans, volatile oils, and other compounds. Pharmacological studies showed that diterpenoids and biflavones showed strong activities, such as antitumor, anti-HIV, and immune regulations. This review hopes to provide a scientific basis for further research and explorations of the medicinal values of the genus.
Animals
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Drugs, Chinese Herbal
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chemistry
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pharmacology
;
Humans
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Molecular Sequence Data
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Molecular Structure
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Thymelaeaceae
;
chemistry
;
classification
6.The Clinical Value of Computerized Tomography in the Evaluation of Pelvic Bone Fractures
Byeong Mun PARK ; Dae Yong HAN ; Chang Dong HAN ; Yun Tae LEE
The Journal of the Korean Orthopaedic Association 1987;22(2):369-374
The clinical value of CT in the diagnosis of pelvic bone fractures is being explored. Conventional radiographic projections, including internal and external oblique views, although very helpful, often cannot provide sufficent jnformation to give a true sense of the fractures. CT conversely displays the anatomy in an axial plane, thereby providing the missing pieces of information and fascilitating classification of these fractures. From January 1983 to June 1986, 34 patients with pelvic bone fractures, admitted to Department of Orthopedic Surgery, Severance Hospital, were given both CT and conventional radiographs. Comparing the conventional radiographic findings with those of CT, the following conclusions were obtained. 1. For patients with multiple trauma who necessitate position changes during conventional radiography, no further change in position was required during CT. 2. CT clearly showed intraarticular loose bodies, anterior wall fractures of the acetabulum, and separations of the saicroiliac joint which were hardly detected on conventional radiographs. 3. CT permitted a better evaluation of the shape, extent, and degree of separation of fracture fragment, so it was very helpful in formulating the treatment plan. 4. Follow-up CT was helpful in evaluating the effectiveness of treatment.
Acetabulum
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Classification
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Diagnosis
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Follow-Up Studies
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Humans
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Joints
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Multiple Trauma
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Orthopedics
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Pelvic Bones
;
Radiography
7.Biliary Tract & Pancreas; Effectiveness of Endoscopic Ultrasonography in Detecting the Extrahepatic Choledocholithiasis.
Im Hwan ROE ; Jung Taik KIM ; Il Han SONG ; Jung Won KIM ; Yun Soo YUN ; Chang Young LIM
Korean Journal of Gastrointestinal Endoscopy 1997;17(1):23-31
BACKGROUND/AIMS: Ultrasonography is the easiest, fastest procedure for the diagnosis of choledocholithiasis, but the diagnostic failure are mostly because of the intrapancreatic level of this condition and the absence of bile duct dillatation. Endoscopic ultrasonography is a promising procedure for the diagnosis of extrahepatic cholestasis due to noninvasiveness and accuracy in the digestive gas interposition. The aim of this study was to prospectively compare the diagnostic accuracy of endoscopie ultrasonography with abdominal ultrasonography and endoscopic retrograde cholangiography in 66 patients with suspected choledocholithiasis. METHODS: All of the patients had abdominal ultrasonography, endoscopic ultrasonography ~and endoscopie retrograde cholangiography within 72 hours and final diagnosis was determined by endoseopic retrograde cholangiography with sphincterotomy. RESULTS: (l) Choledocholithiasis was confirmed in 45 patients: Thirteen patients had nondilated common bile ducts and 20 patients had stones with diamerer < 1 cm. (2) Endoscopic ultrasonography was more sensitive(95.5%) than abdominal ultrasonography (44.4%: P<0.0001) and similar to endoscopic retrograde cholangiography (97.8%). Specificity was same as 100% in 3 diagnostic tools. (3) Endoscopic ultrasonography was superior to abdommal ultrasonography for the diagnosis of choledocholithiasis with nondilated common bile duct(100% vs 15.3%, P<0.0001) and with less than 1cm sized small stone(100% vs 10.0%, P<0.0001). Endoscopic ultrasonography results did not depend on stone diameter or common bile duct dilatation. CONCLUSIONS: Endoscopic ultrasonography could be an accurate and safe diagnostic tool for the diagnosis of choledocholithiasis and could be promising especially in the cases with difficult cannulation of bile duct and gal1 stone pancreatitis.
Bile
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Bile Ducts
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Biliary Tract*
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Catheterization
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Cholangiography
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Choledocholithiasis*
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Cholestasis, Extrahepatic
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Common Bile Duct
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Diagnosis
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Dilatation
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Endosonography*
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Humans
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Pancreas*
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Pancreatitis
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Prospective Studies
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Sensitivity and Specificity
;
Ultrasonography
8.A Case of Childhood Mycosis Fungoides.
Chang Jun CHOI ; Seok Kweon YUN ; Han Uk KIM ; Chull Wan IHM
Korean Journal of Dermatology 1995;33(3):557-563
A 12-year-old boy showed a slatecolored scaly patch on h; ight face for 2 months. Histopathologic findings showed basal vacuolations and dermal me arphages with only scanty lymphoid cells in the fat tissue layer. Besides the facial lesion, lesions of edematous localized erythema were noted on his right if and left buttock with similar mi rocopical findings. 6 months later the facial lesion was aggravated like a cellulitis, of which thc bevpsy findings were consistent with mycosis fungoides. The patient received chemotherapy aftei the diagonsis for one month before his termination. Because of the rarity of mycosis fungoides in childhood age and its un common cutaneous lesions, the case is reported.
Buttocks
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Cellulitis
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Child
;
Dronabinol
;
Drug Therapy
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Erythema
;
Humans
;
Lymphocytes
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Male
;
Mycosis Fungoides*
;
United Nations
9.Tricuspid Regurgitation in Patients with Atrial Septal Defect.
Hye Kyung HAN ; Jae Il SOHN ; Yong Soo YUN ; Chang Yee HONG
Korean Circulation Journal 1988;18(3):411-417
We evaluated the accuracy of a noninvasive method for estimating right ventricular systolic pressures in patients with atrial septal defect and tricuspid regurgitation defected by two-dimensional and Doppler ultrasound. Of 54 patients with atrial septal defect, 24(44%) had jets of tricuspid regurgitation. By use of the maximum velocity(V) of the regurgitatant jet recorded by continuous wave Doppler ultrasound and the Bernoulli equation, we predicted right ventricular systolic pressure(RVP) calculated by the equation of RVP=4V2+10 proposed by Tei et al.The values correlated well with catheterization values(r=0.851, standerd error of estimate=4mmHg). In addition the relation between the Lt to Rt shunt amount and the severity of tricuspid regurgitation was assessed. The severity of tricuspid regurgitation graded on a four-pointscali by pulsed Doppler and two-dimensional echocardiography correlated with Qp/Qs ratio calculated by the Fick's method(p<0.05).
Catheterization
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Catheters
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Echocardiography
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Heart Septal Defects, Atrial*
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Humans
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Tricuspid Valve Insufficiency*
;
Ultrasonography
10.CHONDROBLSTOMA ON TEMPOROMANDIBULAR JOINT, A CASE REPORT.
Hyun Ho CHANG ; Seung Yun HAN ; Hyung Mo AHN ; Won Jong CHOI ; Jae Seung KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(4):756-762
Chondroblastoma is a rare primary bone tumor which originates from cartilage, and represents approximate 1% af all bone tumor. The chondroblastoma arises most frequently from the epiphysis of the long bones with the humerus being the commonest site. It afflicts usually the young under 25 years with greater incidence in male. As there is no cartilage cell on craniofacial bone which is mainly fromed by intramembranous ossification, the chondroblastoma on the craniofacial bone is extremely rare. But the chondroblastoma recurred frequently in craniofacial bone when the mass is excised incompletely or curretted and, as the tumor has the outstanding ability of local invasiveness, it destructs the adjacent bone. In addition, it is difficult to diagnose differentially from sarcoma or giant cell tumor histopathologically. Due to the entities described above, it is necessary to remove the entire tumor mass as complete as possible, to treat with radiation pre or postoperatively for preventing from recurrence, and to observe for a long time. The chondroblastoma on temporal bone is rare and is difficult to diagnose and treat successfully. So we'd like to present a case of chondroblastoma which was originated from temporal side of TMJ with literatural review.
Cartilage
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Chondroblastoma
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Epiphyses
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Giant Cell Tumors
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Humans
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Humerus
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Incidence
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Male
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Recurrence
;
Sarcoma
;
Temporal Bone
;
Temporomandibular Joint*