1.A Case of Ki-1 Positive Large-Cell Lymphoma Transformed from Mycosis Fungoides.
Young Suck RO ; Yun Suck KIM ; Chan Keum PARK
Korean Journal of Dermatology 1999;37(5):641-645
Mycosis fungoides(MF) is a cutaneous T-cell lymphoma of low-grade malignancy characterized by the proliferation of small to medium-sized cerebriform lymphoid cells confined to the skin. It usually shows favorable prognosis, but morphologic transformation occurs in some cases and is often associated with a more aggressive clinical course. Herein we report a case of Ki-1 positive large cell lyrnphoma (Ki-1 LCL) which developed in the plaque stage of mycosis fungoides. Although the lesions responded well to low-dose methotrexate therapy and there was no evidence of local or systemic recurrence until now, continuous follow-up is needed because the prognosis of transformed MF is known to be poor compared with primary cutaneous Ki-1 LCL. We also discussed the differential diagnosis of primary cutaneous Ki-1 positive lymphoproliferative disorders.
Diagnosis, Differential
;
Follow-Up Studies
;
Lymphocytes
;
Lymphoma*
;
Lymphoma, T-Cell, Cutaneous
;
Lymphoproliferative Disorders
;
Methotrexate
;
Mycosis Fungoides*
;
Prognosis
;
Recurrence
;
Skin
2.Incidence of sepsis associated with total parenteral nutrition solutions made in the nursery and pharmacy.
Moon Chan KIM ; Jin Won PARK ; Yun Joo CHUNG
Journal of the Korean Pediatric Society 1992;35(5):646-651
No abstract available.
Incidence*
;
Nurseries*
;
Parenteral Nutrition, Total*
;
Pharmacy*
;
Sepsis*
3.Expression of E-cadherin in Experimental Bladder Carcinogenesis Induced by N-butyl-n-4-hydroxybutyl Nitrosamine.
Yun Chan CHOI ; Eun Sik LEE ; Won Hee PARK
Korean Journal of Urology 2000;41(7):838-843
No abstract available.
Cadherins*
;
Carcinogenesis*
;
Urinary Bladder*
4.A Case of Larsen Syndrome.
Dong Chul PARK ; Chan Jun COE ; Duk Jin YUN
Journal of the Korean Pediatric Society 1987;30(11):1305-1310
No abstract available.
5.Clinical Significance of Double Contrast Arthrography
Key Yong KIM ; Duk Yun CHO ; Chan Il PARK ; Jae Gon SEO ; Jun Sik PARK
The Journal of the Korean Orthopaedic Association 1977;12(4):673-679
Double contrast arthrography has been widely accepted as a method to diagnose the internal derangement of the knee. It is a safe and technically simple procedure permitting accurate diagnosis of lesions of the menisci. In 20 cases operated upon, with the diagnosis of internal derangement of the knee, we performed double contrast arthrography before surgery. We analysed the cases concerning the diagnostic accuracy of arthrography, its clinical significance and discrepancies between arthrographic findings and postoperative lesions. The results were as follows: 1. The cases consisted of 16 cases of meniscal lesion, 4 cases of ligamentous lesion and 3 cases of loose body. 2. In the meniscal lesions, 14 of the 16 cases (87.5%) were diagnosed accurately by arthrography, Therefore arthrography was more useful in diagnosing meniscal lesions as compared with clincal symptoms (69%). 3. In cases of ligamentous lesions arthrography was not significant-ly helfpful, in contrast clinical signs afforded important clues. 4. We encountered 1 case of false positive and 1 case of false negative.
Arthrography
;
Diagnosis
;
Knee
;
Ligaments
;
Methods
6.Secondary primary lung carcinoma after total laryngectomy due to laryngeal carcinoma.
Hwan Kyu RHO ; Doo Yun LEE ; Sang Jin KIM ; Ki Bum LEE ; Chan Il PARK
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(1):98-105
No abstract available.
Laryngectomy*
;
Lung*
7.Echocardiographic Evaluation of Cardiac Functions in Normal Korean Adults.
Jae chan PARK ; Kyung Pyo HONG ; Chong Yun RIM ; Young Bahk KOH ; Young LEE
Korean Circulation Journal 1987;17(2):265-271
To evaluate the cardiac functions we examed the M-mode echocardiography with measurements of blood pressure, heart rate and body surface area in 55 normal Korean adults(male 30 persons, female 25 persons) of mean age, 41.7+/-12.3 years. (1) Interventricular septal thickness is 9.5+/-1.7mm and left ventricular posterior wall thickness are 8.6+/-1.5mm at end-diatole, 14.0+/-2.1mm at end-systole. (2) Diastolic and systolic left ventricular internal dimensions are 49.1+/-4.8mm and 31.3+/-5.0mm, respectively. (3) Left ventricular mass by Penn Convention method is 174.4+/-52.1g and left ventricular mass index is 103.2+/-28.8g/m2. (4) Relative wall thickness is 0.35+/-0.06. (5) Left ventricular volumes by Teichholz's method are 114.9+/-27.6ml at diastole and 40.2+/-17.2ml at systole. Therefore, stroke volume is 74.7+/-16.9ml and stroke volume index is 44.5+/-10.7 ml/m2. (6) Cardiac output is 4944+/-1058 ml/min and cardiac index is 2951+/-666 ml/min/m2. (7) Total peripheral resistance is 1454+/-356 dynes-sec-cm(-5) and total peripheral resistance index is 2472+/-623 dynes-sec-cm(-5).m2. (8) Fractional shortening is 36.5+/-6.0% and pressure-volume ratio is 3.27+/-1.19 mmHg/ml. (9) End-systolic wall stress is 61.3+/-19.7x10(3) dynes=cm2. (10) Atrial emptying index is 0.66+/-0.18.
Adult*
;
Blood Pressure
;
Body Surface Area
;
Cardiac Output
;
Diastole
;
Echocardiography*
;
Female
;
Heart Rate
;
Humans
;
Stroke Volume
;
Systole
;
Vascular Resistance
8.Metamerism in composite resins under five standard illuminants - D65, A, C, FCW and TL84.
Ki Jeong PARK ; Yun Chan HWANG ; Sun Ho KIM ; Won Mann OH ; In Nam HWANG
Journal of Korean Academy of Conservative Dentistry 2003;28(5):402-408
This study was done to present a criterion in selection of the most proper light sources and materials by measuring metamerism index(MI) of the light curing composite resins with spectrocolorimeter. Metamerism is defined when two objects appear to be the same color in one illuminant but different in another. This is due to the fact that they have different spectral curves that fail to match under the second illuminant. In this study, A1 & A3 shade of five light curing composite resins (Esthet-X, Filteck Z250, Filteck A110, Charisma, Vitalescence) were chosen based on Vita shade. Five samples were made for shade of each product with Teflon mold (diameter: 15mm, thickness: 2mm). Metamerism index of each samples on a Barium sulfate plate (L*=96.54, a*=0.19, b*=0.01) prepared for sample fixation were measured with spectrocolorimeter(Miniscan XE plus, Model 4000s, Hunter Lab, USA) by applying standard light source D65, C, Fcw, TL84 and A. Standardization was done with reference standard (X=80.8, Y=85.7, Z=90.8) and light trap. The results were as follows. 1. Different resins with same Vita shade showed recognizable color difference(DeltaE*>2). 2. All composites had MI below accepted value 0.5 between standard illuminant(D65, C, & A) and below 1.5 under fluorescent condition (Fcw & TL84). 3. MI value between D65 and A showed higher value than MI value between other source of light(p<0.01). 4. All resins except Z250 showed MI value that A3 is higher than A1 between D65 and A(p<0.05).
Barium Sulfate
;
Composite Resins*
;
Fungi
;
Polytetrafluoroethylene
9.Expression of Cyclin B1 and cdc2 in Nodal Non-Hodgkin's Lymphoma and its Prognostic Implications.
Journal of Korean Medical Science 2002;17(3):322-327
To investigate the role of cyclin B1 and cdc2 in the pathogenesis and progression of malignant lymphoma, 68 cases of nodal non-Hodgkin's lymphoma were examined about the expression of cyclin B1 and cdc2 along with p53 and Ki-67 by immunohistochemical method. The correlation of their expression with various clinicopathologic findings was also analyzed. Cyclin B1 and cdc2 were diffusely expressed in 39 cases (57.4%) and 54 cases (79.4%) out of 68 cases studied, respectively. The mean labeling indices of cyclin B1 and cdc2 in malignant lymphoma were 31.9% and 68.0%, respectively. In normal lymphoid tissues, cyclin B1 and cdc2 were expressed predominantly in the germinal center with mean labeling indices of 13.9% and 28.3%, respectively. The correlation between the expression of cyclin B1 and cdc2 was noted (p=0.013). The expression of Ki-67 was correlated with that of cyclin B1 (p=0.023) and marginally correlated with that of cdc2 (p=0.056). The expression of cdc2 and p53 in complete remission group to chemotherapy was lower than that of progressive disease group (p=0.047, p=0.049). In multivariate analysis, the clinical stage alone showed significance on overall survival (p=0.049). In conclusion, cyclin B1 and cdc2 appeared to be involved in the genesis or progression of malignant lymphoma and cdc2 can be a useful marker for response to chemotherapy.
Adolescent
;
Adult
;
Aged
;
CDC2 Protein Kinase/*biosynthesis
;
Child
;
Child, Preschool
;
Cyclin B/*biosynthesis
;
Cyclin B1
;
Female
;
Humans
;
Immunohistochemistry
;
Ki-67 Antigen/biosynthesis
;
Lymph Nodes/metabolism/pathology
;
*Lymphoma, Non-Hodgkin/metabolism/mortality/pathology
;
Male
;
Middle Aged
;
Palatine Tonsil/metabolism/pathology
;
Predictive Value of Tests
;
Prognosis
;
Survival Analysis
;
Tumor Suppressor Protein p53/biosynthesis
10.The Effect of Bupivacaine on the Methemoglobin Formation .
Korean Journal of Anesthesiology 1982;15(1):74-80
The changes of methemoglobin concentration in the blood after the use of lidocatine or Marcaine were investigated in the human and the rabbits. In the human the drugs were give by the epidural route and intramuscularly in rabbits. Lidocaine did not increase the methemoglobin concentration in humans but marcaine increased the methemoglobin concentration in the blood.
Bupivacaine*
;
Humans
;
Lidocaine
;
Methemoglobin*
;
Rabbits