1.Treatment of fracture of ulna coronoid process
Yuming ZUO ; Zhiqiang WANG ; Yueguang WANG
Chinese Journal of Orthopaedics 2001;0(06):-
Objective To explore the treatment of fracture of ulna coronoid process. Methods Sixty-five patients (66 cases) of fractures of ulna coronoid process were treated between January 1997 and April 2005. There were 54 males and 11 females with an average age of 32 years old (range, 8-76 years old). 29 fractures occurred on the left extremity, 35 on the right and 1 on the bilateral. The mechanism of injury was fall in 23 sides, traffic injury in 16, wringer injury in 14, fall from a height in 10 and other trauma in 3. 60 cases were fresh fractures, 6 old fractures and 7 open fractures. 38 patient suffered multiple fractures in ipsilateral elbow. According to Regan-Morrey classification, there were 22 type Ⅰ, 30 type Ⅱ and 8 type Ⅲ. In addition, there were 6 cases with a sagittal fracture line which we defined them as "type Ⅳ". In this series, immobilization of the elbow in flexion or extension with a long arm plaster splint or cast were applied in 37 sides, open reduction and internal fixation in 23 sides, resection of fragments in 5 sides and reconstruction of coronoid process in 1. Results 43 cases(44 sides) were followed up for an average 15 months (range, 7-32 months). All the fractures healed well, and the averaged union time was 12.2 weeks with a range of 6-16 weeks. The clinical results were evaluated according to Morrey's scale, 25 sides (56.8%) were rated as excellent, 9 (20.5%) as good, 6 (13.6%) as fair and 4(9.1%) as poor. No deep infection, loosening or breakage of the internal fixators and other severe complications occurred except for 2 cases with subluxation of elbow joint and 2 cases with myositis ossificans. Conclusion For type I and some cases with a stable typeⅡand Ⅳ which have no or mildly displaced fragment of the coronoid process, conservative treatment are applicable. Open reduction and internal fixation are suitable for all type Ⅲ and some cases with an unstable typeⅡ and Ⅳ which have a obviously displaced fragment of the coronoid process.
2.Observation on proliferation and collagen secretion of the transplanted human fibroblasts in nude mice
Yuming ZHAO ; Junsheng DING ; Jin ZUO ; Fude FANG ; Jiaqi WANG
Basic & Clinical Medicine 2006;0(10):-
Objective To investigate the proliferation and collagen secretion of transplanted human fibroblasts.Methods The solution containing human fibroblasts(2?1010L-1)was prepared and 1 mL was injected into the dermis of BALB/CNU nude mice.Animals were killed by the end of the 1st,2nd and 3rd month after injection.The dermis in the injected area was taken out and stained with HE.Immunohistochemical staining for type I and type Ⅲ collagen was performed at the same time.Results Mitosis was observed by the end of the 1st,2nd and 3rd month.The concentration of type I and type Ⅲ collagen in the extra cellular matrix increased with the passing of time.Conclusion Transplanted human fibroblasts can proliferate automatically in the dermis of nude mice and manufacture the type I and type Ⅲ collagen in situ.Long period of survival and secretion will make it possible for fibroblasts to become promising option to correct minimal tissue defects.
3.Application of septal extension grafts with auricular cartilage in rhinoplasty.
Yuming SUN ; Shaorong LEI ; Fengzhen QIU ; Chenchen ZUO ; Pengju FAN ; Jianhong LONG ; Wuyuan TAN
Journal of Central South University(Medical Sciences) 2022;47(10):1392-1397
OBJECTIVES:
Rhinoplasty is one of the most common cosmetic surgeries in China. Septal extension grafts (SEG) have been widely used in rhinoplasty, but there are few reports on SEG derived from ear cartilage. This study aims to explore the effectiveness and stability of auricular cartilage nasal SEG transplantation in Chinese rhinoplasty.
METHODS:
A retrospective analysis of 35 rhinoplasty patients admitted from September 2019 to March 2022 has been conducted. Among them, 29 patients underwent rhinoplasty for the first time and 6 patients underwent rhinoplasty with the age of 18-32 (average 22.4) years old. The postoperative follow-up was 3-28 (average 18.5) months. The improvement of the nose shape was observed. The changes of the nose tip angle, nasolabial angle, and nasofrontal angle were compared between before and after the operation, and the complications were recorded.
RESULTS:
All patients who underwent rhinoplasty with a septal extension grafts constructed from the concha cavity and concha cartilage showed significant improvement in nasal contour. The preoperative nasal tip angle, nasolabial angle, and nasofrontal angle were significantly improved compared with 3 months after operation (all P<0.001), and there was no significant difference between 3 months and 14 months after operation (all P>0.05). The appearance of nasal cavity was satisfactory in 32 patients after operation. Columella deviation occurred in 2 patients and 1 patient complained of downward rotation of the nasal tip, which was satisfied after readjustment of the graft.
CONCLUSIONS
The simplified SEG derived from auricular cartilage can provide stable support for the nasal tip, the nasal shape is natural after operation, and minimal trauma of unilateral auricle cartilage transplantation remains.
Humans
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Young Adult
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Adult
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Rhinoplasty
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Ear Cartilage/transplantation*
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Retrospective Studies
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Nasal Septum/transplantation*
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Plastic Surgery Procedures