1.Clinical study on the treatment of radiodermatitis with acupoint massage and wet compress of Chinese medicine
Yumei XING ; Xiuna YU ; Yuanfang JIANG ; Chao SUI
International Journal of Traditional Chinese Medicine 2010;32(5):427-
Objective To study the clinical effects of treating radiodermatis with acupoint massage and wet compress of Chinese medicine. Methods 104 patients with radiodermatis were randomly recruited into a control group and a treatment group, with 52 patients in each group. The treatment group was treated with acupoint massage plus wet compress of chiense medicines; with the treatment group was externally applied with Kangbao Shaoshang moistening ointment. The result was compared after the treatment. Results The time for easement of pain in the treatment group was obvious reduced than the control group after the treatment. The total effective rate was 96.1% and 57.69% in the treatment group and the control group respectively, the difference showing statistical significance (χ2=27.3, P<0.01). Conclusion It was effective to treat radiodermatitis with acupoint massage and wet compress of Chinese medicine.
2.Roles of galanin peptide in tumorigenesis and tumor progression
Yumei SUI ; Penghua FANG ; Mingyi SHI ; Ping BU
Journal of International Oncology 2012;39(10):738-741
Galanin is a peptide with wide-ranging effects,especially within the central,peripheral nervous system and endocrine system.Many tumors of neuroendocrine origin,and also an increasing number of non-neuroendocrine cancers,have been shown to express galanin and/or its receptors.Expression of galanin peptide has been detected in pheochromocytoma,squamous cell carcinoma,pituitary adenoma,gastrointestinal cancers and so on.Galanin peptide plays an important role in tumori-genesis and progression of many kinds of tumors.Therefore,studying the roles of galanin and its receptors are helpful for diagnosis and treatment of tumors.
3.The study on hepatocarcinoma cells cotransfected with B7.1 and SEA genes
Yumei ZHANG ; Yanfang SUI ; Quanjian YAN ; Zengshan LI ; Jun YU
Journal of Cellular and Molecular Immunology 2001;17(4):313-314,340
Aim To obtain the HCC cell lines which could coexpressed the B7.1 and SEA. Methods The positive clones expressing the B7.1 and SEA were screened by immunohistochemical staining. The amount of SEA in culture supernatant was detected by ELISA. Results HCC cell clones coexpressing B7.1 and SEA were obtained, and expression amount of SEA in culture supernatant reached 10~ 14× 10-8g/L. Conclusion The co-rec-ogenition immune effective system of SEA and B7.1 on HCC cells is established.
4.The Impact of Severity of Psoriasis on Quality of Life in Psoriatic Patients
Jihai SHI ; Longqing XIA ; Qun WANG ; Daguang WANG ; Qiang JU ; Yan XIN ; Xiaojing KANG ; Xiuzhen HE ; Lianjin SUI ; Yumei ZHONG ; Changgeng SHAO
Chinese Journal of Dermatology 1995;0(03):-
Objective To investigate the impact of severity of psoriasis on quality of life in patients with psoriasis vulgaris.Methods A questionnaire interview was carried out to the outpatients with psoriasis vulgaris(n=504)from Dec.2000to Sept.2001.All the patients were more than18years old.The content of questionnaire included daily life and activities,work and school performance,social activities and personal relationships,and psychologic status.Disease severity was assessed with psoriasis area and severity index(PASI).498patients were included for the final analysis.Statistical analysis was performed with SPSS software package.Results63.3%patients were restricted in their food selection.40.2%had bad sleep,59.0%could not dress short clothes in the summer.26.5%were restricted in use of public traffic and services.15.1%were rejected in haircut and cosmetic service.31.2%had decreased income along with severity of the disease.58.8%felt uncomfortable in social activities and public places.25.8%avoided handshaking with others.43.3%were reluctant in social intercourse.29.0%were not willing to take part in social activities,especially for moderate and severe cases.54.9%felt that their self-esteem was injured.26.6%thought that other peoples always avoided to meet them.64.4%felt anxiety for their disease.83.1%often worried about relapse or exacerbation of psoriasis.15.9%showed a tendency to commit suicide.Conclusions The more severe the disease is the more impact it may have on the daily life,work and school performance,social activities and personal relationship,and psychologic status in patients with psoriasis vulgaris.It is reccommended that besides the conventional treatment bio-psychic and social medical management be given to the patients especially for moderate and severe cases.