Objective To observe the efficacy and safety of BiPAP ventilator combined with nikethamide for the chronic obstructive pulmonary disease (COPD)complicated with type II respiratory failure.Methods 76 COPD patients complicated with type II respiratory failure were selected as the research subjects,they were randomly divided into two groups by single blind and randomized method,38 cases in each group.The control group was treated with nikethamide therapy,while the observation group used BiPAP combined with mechanical ventilation therapy.The clinical therapeutic effect and adverse reactions were analyzed and compared in the two groups.Results The total effective rate in the observation group was 92.11%,which was significantly higher than 68.42% in the control group (χ2 =10.54,P <0.05).After treatment,the HR and RR of the observation group were (94.28 ±7.62)/min, (13.27 ±4.41)/min,which were significantly decreased than before treatment (t =8.02,8.04,all P <0.05),and which were significantly lower than those in the control group (t =7.54,6.88,P <0.05).After treatment,the pH (7.39 ±0.06),PaO2 (96.31 ±5.44)mmHg,SaO2 (98.42 ±6.87)% in the observation group were significantly increased (t =7.56,7.76,7.45,all P <0.05),PaCO2 (57.36 ±4.98)mmHg was significantly decreased (t =7.54, P <0.05),which had significant differences with the control group (t =6.56,7.02,6.73,7.32,all P <0.05).There was no significant difference in the incidence of adverse reactions between the two groups (χ2 =2.14,P >0.05). Conclusion BiPAP ventilator combined with nikethamide meters has remarkable curative effect and high safety in treatment of COPD patients complicated with type II respiratory failure,which is worthy of clinical reference and popularization.

ObjectiveTo investigate the value of 64-slice CT urography (CTU) in diagnosis of urologic diseases.Methods Sixty patients with suspected urinary system diseases underwent 64-slice CT volume scanning and 3D reconstructions.The diagnostic value of 64-slice CTU was evaluated.ResultsThere were 14 patients with urinary system cancers,2 with ureter polyp,9 with tuberculosis of urinary system,13 with urinary system calculus,13 with nonmalignant ureterostenosis combined with hydronephrosis,2 with ureterostenosis and hydronephrosis induced by nearby organic damage,2 with traumatism,1 with renal occlusion,as well as 4 after urinary tract surgeries and 2 without abnormality.Totally 28 cases was confirmed with surgery and pathology,the sensitivity,specificity and accuracy of MSCTU for upper tract tumor was 100％(14/14),85.71％ (12/14) and 92.86％ (26/28),respectively.ConclusionMSCTU is able to directly and clearly show urologic diseases.It can be regarded as the first choice in patients with clinically suspected urinary tract diseases,especially tumors.