Total muscle mass is thought of as one of the intrinsic limiting factors of aerobic power. But it is not yet clarified how the total muscle mass limits the magnitude of aerobic power. The purpose of this study was to clarify the relationship between total muscle mass and aerobic power and to make a further discussion conscerning its limiting factors. 17 sedentary students with a mean age of 19.3 (18-23) years, and 17 varsity footballers 19.9 (19-21) years old, were measured for lean body mass, which was an approximate indicator of the total muscle mass, by underwater-weighing method and VO₂ max by bicycle ergometer. The correlationship between lean body mass and VO₂max for sedentary students was found to be higher (r=0.821) than for footballers (r=0.595) . It was also shown that footballers had a significantly larger VO₂max per 1kg of lean body mass than sedentary students. Previous studies showed that the increment of VO₂max through endurance training was caused by the increment of such factors as mitochondria, maximum cardiac output and maximum stroke volume, and was not by lean body mass. So, it was concluded that lean body mass was a reasonable limiting factor for sedentary students, but was not a stable factor of VO₂max because of lower linearlity for footballers and the significant difference on VO₂max per 1kg of lean body mass between two groups.

Esophageal cancer has one of the highest malignant potentials of any type of tumor. The 3-field lymph node dissection is the standard procedure in Japan for surgically curable esophageal cancer in the middle or upper thoracic esophagus. Minimally invasive esophagectomy is being increasingly performed in many countries, and several studies report its feasibility and curability; further, the magnifying effect of the thoracoscope is another distinct advantage. However, few studies have reported that minimally invasive esophagectomy is more beneficial than open esophagectomy. A recent meta-analysis revealed that minimally invasive esophagectomy reduces blood loss, respiratory complications, the total morbidity rate, and hospitalization duration. A randomized study reported that the pulmonary infection rate, pain score, intraoperative blood loss, hospitalization duration, and postoperative 6-week quality of life were significantly better with the minimally invasive procedure than with other procedures. In the future, sentinel lymph node mapping might play a significant role by obtaining individualized information to customize the surgical procedure for individual patients' specific needs.
Esophageal Neoplasms ; Esophagectomy ; Esophagus ; Hospitalization ; Imidazoles ; Japan ; Lymph Node Excision ; Lymph Nodes ; Nitriles ; Nitro Compounds ; Pyrethrins ; Quality of Life ; Surgical Procedures, Minimally Invasive ; Thoracic Surgery, Video-Assisted ; Thoracoscopes

Introduction: This study aimed to determine the trends in the use of medicines that can affect the recognition function of patients aged ≧70 years. Since 2015 when the “Safe Drug Treatment Guidelines for the Elderly” was revised, these medicines are dispensed at a community pharmacy located in a satellite city. Methods: We compared the dispensing results from 2014 to 2015-2019 and investigated the ratio of prescriptions containing the medicines that can affect the recognition function using the clinical department and medicine type. Results: Prescriptions containing medicines that can affect recognition function have been on a downward trend since 2015. During this period, the number of medicines per prescription did not decrease, and the medicines that can affect recognition function were replaced with other medicines. On the other hand, no decrease in the number of medicines that can affect recognition function was observed in internal medicine. In medicine type, the ratio of benzodiazepines drugs decreased; however, it increased again in 2019. Conclusion: There was a decreasing trend in the use of medicines that can affect recognition function of the elderly in departments other than internal medicine after 2015.