1.Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults
Hyuma MAKIZAKO ; Yuki NAKAI ; Shoma AKAIDA ; Yoshiaki TANIGUCHI ; Takaki MIWA ; Shigeto MORIMOTO
Annals of Geriatric Medicine and Research 2024;28(2):178-183
Background:
This study examined the association between memory function and reduced olfactory and gustatory function among independent community-dwelling older adults.
Methods:
This cross-sectional study included 127 older adults (65.4% women). We assessed their memory, odor, and taste identification skills. Open essence (OE) test and taste strips (TS) were used to identify hyposmia (OE test ≤6) and hypogeusia (TS test ≤8), respectively.
Results:
Participants with severe hyposmia had significantly poorer memory functions compared to participants without severe hyposmia. After adjusting for covariates, multivariate logistic regression models revealed a significant association between immediate recognition performance and a decreased likelihood of severe hyposmia (odds ratio=0.65; 95% confidence interval 0.47–0.90). We observed no significant association between taste function and memory.
Conclusion
Memory function may be associated with olfactory impairment in older adults.
2.Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults
Hyuma MAKIZAKO ; Yuki NAKAI ; Shoma AKAIDA ; Yoshiaki TANIGUCHI ; Takaki MIWA ; Shigeto MORIMOTO
Annals of Geriatric Medicine and Research 2024;28(2):178-183
Background:
This study examined the association between memory function and reduced olfactory and gustatory function among independent community-dwelling older adults.
Methods:
This cross-sectional study included 127 older adults (65.4% women). We assessed their memory, odor, and taste identification skills. Open essence (OE) test and taste strips (TS) were used to identify hyposmia (OE test ≤6) and hypogeusia (TS test ≤8), respectively.
Results:
Participants with severe hyposmia had significantly poorer memory functions compared to participants without severe hyposmia. After adjusting for covariates, multivariate logistic regression models revealed a significant association between immediate recognition performance and a decreased likelihood of severe hyposmia (odds ratio=0.65; 95% confidence interval 0.47–0.90). We observed no significant association between taste function and memory.
Conclusion
Memory function may be associated with olfactory impairment in older adults.
3.Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults
Hyuma MAKIZAKO ; Yuki NAKAI ; Shoma AKAIDA ; Yoshiaki TANIGUCHI ; Takaki MIWA ; Shigeto MORIMOTO
Annals of Geriatric Medicine and Research 2024;28(2):178-183
Background:
This study examined the association between memory function and reduced olfactory and gustatory function among independent community-dwelling older adults.
Methods:
This cross-sectional study included 127 older adults (65.4% women). We assessed their memory, odor, and taste identification skills. Open essence (OE) test and taste strips (TS) were used to identify hyposmia (OE test ≤6) and hypogeusia (TS test ≤8), respectively.
Results:
Participants with severe hyposmia had significantly poorer memory functions compared to participants without severe hyposmia. After adjusting for covariates, multivariate logistic regression models revealed a significant association between immediate recognition performance and a decreased likelihood of severe hyposmia (odds ratio=0.65; 95% confidence interval 0.47–0.90). We observed no significant association between taste function and memory.
Conclusion
Memory function may be associated with olfactory impairment in older adults.
4.Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults
Hyuma MAKIZAKO ; Yuki NAKAI ; Shoma AKAIDA ; Yoshiaki TANIGUCHI ; Takaki MIWA ; Shigeto MORIMOTO
Annals of Geriatric Medicine and Research 2024;28(2):178-183
Background:
This study examined the association between memory function and reduced olfactory and gustatory function among independent community-dwelling older adults.
Methods:
This cross-sectional study included 127 older adults (65.4% women). We assessed their memory, odor, and taste identification skills. Open essence (OE) test and taste strips (TS) were used to identify hyposmia (OE test ≤6) and hypogeusia (TS test ≤8), respectively.
Results:
Participants with severe hyposmia had significantly poorer memory functions compared to participants without severe hyposmia. After adjusting for covariates, multivariate logistic regression models revealed a significant association between immediate recognition performance and a decreased likelihood of severe hyposmia (odds ratio=0.65; 95% confidence interval 0.47–0.90). We observed no significant association between taste function and memory.
Conclusion
Memory function may be associated with olfactory impairment in older adults.
5.Associations of Eating Out and Dietary Diversity with Mild Cognitive Impairment among Community-Dwelling Older Adults
Yuto KIUCHI ; Hyuma MAKIZAKO ; Yuki NAKAI ; Yoshiaki TANIGUCHI ; Shoma AKAIDA ; Mana TATEISHI ; Mika KIMURA ; Toshihiro TAKENAKA ; Takuro KUBOZONO ; Kota TSUTSUMIMOTO ; Hiroyuki SHIMADA ; Mitsuru OHISHI
Annals of Geriatric Medicine and Research 2024;28(3):266-272
Background:
Dementia is a critical late-life health issue that occurs among members of aging societies. This study examined the relationships between eating out, dietary diversity, and mild cognitive impairment (MCI) among community-dwelling older adults.
Methods:
We analyzed data from 597 older adults (median age 73.0 years, interquartile range 69.0–78.0 years; 62.6% females). We applied the food frequency score to evaluate diet variety and the weekly consumption frequencies of ten food items were determined. The National Center for Geriatrics and Gerontology Functional Assessment Tool (NCGG-FAT) was used to evaluate MCI. Finally, we asked the participants how often they ate out each month; those who replied "none" were categorized into the "non-eating out" group.
Results:
The overall prevalence of MCI was 122 (20.4%), with a higher prevalence in the low dietary diversity group than in the high dietary diversity group (28.6% vs. 18.6%). After adjusting for covariates, the participants who self-described as not eating out were independently associated with low dietary diversity (odds ratio [OR]=1.97, 95% confidence interval [CI] 1.20–3.20), while low dietary diversity was associated with MCI (OR=1.72; 95% CI 1.02–2.87). Structural equation models revealed that not eating out had no direct effect on MCI but was associated with MCI via low dietary diversity (root mean square error of approximation=0.030, goodness-of-fit index=0.999, and adjusted goodness-of-fit index=0.984).
Conclusions
Although non-eating out may not have a direct effect on MCI, an indirect relationship may exist between eating-out habits and MCI via dietary diversity status.
6.Associations of Eating Out and Dietary Diversity with Mild Cognitive Impairment among Community-Dwelling Older Adults
Yuto KIUCHI ; Hyuma MAKIZAKO ; Yuki NAKAI ; Yoshiaki TANIGUCHI ; Shoma AKAIDA ; Mana TATEISHI ; Mika KIMURA ; Toshihiro TAKENAKA ; Takuro KUBOZONO ; Kota TSUTSUMIMOTO ; Hiroyuki SHIMADA ; Mitsuru OHISHI
Annals of Geriatric Medicine and Research 2024;28(3):266-272
Background:
Dementia is a critical late-life health issue that occurs among members of aging societies. This study examined the relationships between eating out, dietary diversity, and mild cognitive impairment (MCI) among community-dwelling older adults.
Methods:
We analyzed data from 597 older adults (median age 73.0 years, interquartile range 69.0–78.0 years; 62.6% females). We applied the food frequency score to evaluate diet variety and the weekly consumption frequencies of ten food items were determined. The National Center for Geriatrics and Gerontology Functional Assessment Tool (NCGG-FAT) was used to evaluate MCI. Finally, we asked the participants how often they ate out each month; those who replied "none" were categorized into the "non-eating out" group.
Results:
The overall prevalence of MCI was 122 (20.4%), with a higher prevalence in the low dietary diversity group than in the high dietary diversity group (28.6% vs. 18.6%). After adjusting for covariates, the participants who self-described as not eating out were independently associated with low dietary diversity (odds ratio [OR]=1.97, 95% confidence interval [CI] 1.20–3.20), while low dietary diversity was associated with MCI (OR=1.72; 95% CI 1.02–2.87). Structural equation models revealed that not eating out had no direct effect on MCI but was associated with MCI via low dietary diversity (root mean square error of approximation=0.030, goodness-of-fit index=0.999, and adjusted goodness-of-fit index=0.984).
Conclusions
Although non-eating out may not have a direct effect on MCI, an indirect relationship may exist between eating-out habits and MCI via dietary diversity status.
7.Associations of Eating Out and Dietary Diversity with Mild Cognitive Impairment among Community-Dwelling Older Adults
Yuto KIUCHI ; Hyuma MAKIZAKO ; Yuki NAKAI ; Yoshiaki TANIGUCHI ; Shoma AKAIDA ; Mana TATEISHI ; Mika KIMURA ; Toshihiro TAKENAKA ; Takuro KUBOZONO ; Kota TSUTSUMIMOTO ; Hiroyuki SHIMADA ; Mitsuru OHISHI
Annals of Geriatric Medicine and Research 2024;28(3):266-272
Background:
Dementia is a critical late-life health issue that occurs among members of aging societies. This study examined the relationships between eating out, dietary diversity, and mild cognitive impairment (MCI) among community-dwelling older adults.
Methods:
We analyzed data from 597 older adults (median age 73.0 years, interquartile range 69.0–78.0 years; 62.6% females). We applied the food frequency score to evaluate diet variety and the weekly consumption frequencies of ten food items were determined. The National Center for Geriatrics and Gerontology Functional Assessment Tool (NCGG-FAT) was used to evaluate MCI. Finally, we asked the participants how often they ate out each month; those who replied "none" were categorized into the "non-eating out" group.
Results:
The overall prevalence of MCI was 122 (20.4%), with a higher prevalence in the low dietary diversity group than in the high dietary diversity group (28.6% vs. 18.6%). After adjusting for covariates, the participants who self-described as not eating out were independently associated with low dietary diversity (odds ratio [OR]=1.97, 95% confidence interval [CI] 1.20–3.20), while low dietary diversity was associated with MCI (OR=1.72; 95% CI 1.02–2.87). Structural equation models revealed that not eating out had no direct effect on MCI but was associated with MCI via low dietary diversity (root mean square error of approximation=0.030, goodness-of-fit index=0.999, and adjusted goodness-of-fit index=0.984).
Conclusions
Although non-eating out may not have a direct effect on MCI, an indirect relationship may exist between eating-out habits and MCI via dietary diversity status.
8.Associations of Eating Out and Dietary Diversity with Mild Cognitive Impairment among Community-Dwelling Older Adults
Yuto KIUCHI ; Hyuma MAKIZAKO ; Yuki NAKAI ; Yoshiaki TANIGUCHI ; Shoma AKAIDA ; Mana TATEISHI ; Mika KIMURA ; Toshihiro TAKENAKA ; Takuro KUBOZONO ; Kota TSUTSUMIMOTO ; Hiroyuki SHIMADA ; Mitsuru OHISHI
Annals of Geriatric Medicine and Research 2024;28(3):266-272
Background:
Dementia is a critical late-life health issue that occurs among members of aging societies. This study examined the relationships between eating out, dietary diversity, and mild cognitive impairment (MCI) among community-dwelling older adults.
Methods:
We analyzed data from 597 older adults (median age 73.0 years, interquartile range 69.0–78.0 years; 62.6% females). We applied the food frequency score to evaluate diet variety and the weekly consumption frequencies of ten food items were determined. The National Center for Geriatrics and Gerontology Functional Assessment Tool (NCGG-FAT) was used to evaluate MCI. Finally, we asked the participants how often they ate out each month; those who replied "none" were categorized into the "non-eating out" group.
Results:
The overall prevalence of MCI was 122 (20.4%), with a higher prevalence in the low dietary diversity group than in the high dietary diversity group (28.6% vs. 18.6%). After adjusting for covariates, the participants who self-described as not eating out were independently associated with low dietary diversity (odds ratio [OR]=1.97, 95% confidence interval [CI] 1.20–3.20), while low dietary diversity was associated with MCI (OR=1.72; 95% CI 1.02–2.87). Structural equation models revealed that not eating out had no direct effect on MCI but was associated with MCI via low dietary diversity (root mean square error of approximation=0.030, goodness-of-fit index=0.999, and adjusted goodness-of-fit index=0.984).
Conclusions
Although non-eating out may not have a direct effect on MCI, an indirect relationship may exist between eating-out habits and MCI via dietary diversity status.
9.Outcome of intradiscal condoliase injection therapy for patients with recurrent lumbar disc herniation
Noritaka SUZUKI ; Yawara EGUCHI ; Takashi HIRAI ; Takuya TAKAHASHI ; Yohei TAKAHASHI ; Kota WATANABE ; Tomohiro BANNO ; Kyohei SAKAKI ; Satoshi MAKI ; Yuuichi TAKANO ; Yuki TANIGUCHI ; Yasuchika AOKI ; Takamitsu KONISHI ; Yutaka HIRAIZUMI ; Masatsune YAMAGATA ; Akihiro HIRAKAWA ; Seiji OHTORI
Asian Spine Journal 2024;18(4):550-559
Methods:
The study participants were 249 patients who underwent intradiscal condoliase injection for LDH at nine participating institutions, including 241 patients with initial LDH (group C) and eight with recurrent LDH (group R). Patient characteristics including age, sex, body mass index, disease duration, intervertebral LDH level, smoking history, and diabetes history were evaluated. Low back pain/leg pain Numerical Rating Scale (NRS) scores and the Oswestry Disability Index (ODI) were used to evaluate clinical symptoms before treatment and at 6 months and 1 year after treatment.
Results:
Low back pain NRS scores (before treatment and at 6 months and 1 year after treatment, respectively) in group C (4.9 → 2.6 → 1.8) showed significant improvement until 1 year after treatment. Although a tendency for improvement was observed in group R (3.5 → 2.8 → 2.2), no significant difference was noted. Groups C (6.6 → 2.4 → 1.4) and R (7.0 → 3.1 → 3.2) showed significant improvement in the leg pain NRS scores after treatment. Group C (41.4 → 19.5 → 13.7) demonstrated significant improvement in the ODI up to 1 year after treatment; however, no significant difference was found in group R (35.7 → 31.7 → 26.4).
Conclusions
Although intradiscal condoliase injection is less effective for LDH recurrence than for initial cases, it is useful for improving leg pain and can be considered a minimally invasive and safe treatment method.
10.Outcome of intradiscal condoliase injection therapy for patients with recurrent lumbar disc herniation
Noritaka SUZUKI ; Yawara EGUCHI ; Takashi HIRAI ; Takuya TAKAHASHI ; Yohei TAKAHASHI ; Kota WATANABE ; Tomohiro BANNO ; Kyohei SAKAKI ; Satoshi MAKI ; Yuuichi TAKANO ; Yuki TANIGUCHI ; Yasuchika AOKI ; Takamitsu KONISHI ; Yutaka HIRAIZUMI ; Masatsune YAMAGATA ; Akihiro HIRAKAWA ; Seiji OHTORI
Asian Spine Journal 2024;18(4):550-559
Methods:
The study participants were 249 patients who underwent intradiscal condoliase injection for LDH at nine participating institutions, including 241 patients with initial LDH (group C) and eight with recurrent LDH (group R). Patient characteristics including age, sex, body mass index, disease duration, intervertebral LDH level, smoking history, and diabetes history were evaluated. Low back pain/leg pain Numerical Rating Scale (NRS) scores and the Oswestry Disability Index (ODI) were used to evaluate clinical symptoms before treatment and at 6 months and 1 year after treatment.
Results:
Low back pain NRS scores (before treatment and at 6 months and 1 year after treatment, respectively) in group C (4.9 → 2.6 → 1.8) showed significant improvement until 1 year after treatment. Although a tendency for improvement was observed in group R (3.5 → 2.8 → 2.2), no significant difference was noted. Groups C (6.6 → 2.4 → 1.4) and R (7.0 → 3.1 → 3.2) showed significant improvement in the leg pain NRS scores after treatment. Group C (41.4 → 19.5 → 13.7) demonstrated significant improvement in the ODI up to 1 year after treatment; however, no significant difference was found in group R (35.7 → 31.7 → 26.4).
Conclusions
Although intradiscal condoliase injection is less effective for LDH recurrence than for initial cases, it is useful for improving leg pain and can be considered a minimally invasive and safe treatment method.